Considerations for controlling invasive meningococcal disease in high income countries.

abstract：:Vaccination of health-care workers (HCWs) against seasonal influenza has been consistently recommended worldwide in order to prevent nosocomial transmission and ensure delivery of health-care services during outbreaks. We describe the effects of a nationwide campaign to promote influenza vaccination among HCWs working...

journal_title：Vaccine

authors： Dedoukou X,Nikolopoulos G,Maragos A,Giannoulidou S,Maltezou HC

更新日期：2010-08-23 00:00:00

abstract：:Schistosomiasis is an important parasitic disease for which there is no available vaccine. We have focused on a functionally important antigen of Schistosoma mansoni, Sm-p80, as a vaccine candidate because of its consistent immunogenicity, protective potential and antifecundity effect observed in murine models; and fo...

journal_title：Vaccine

authors： Ahmad G,Zhang W,Torben W,Damian RT,Wolf RF,White GL,Chavez-Suarez M,Kennedy RC,Siddiqui AA

更新日期：2009-05-11 00:00:00

abstract：:Measles remains a major cause of worldwide infant mortality despite the use of current live attenuated vaccines. New approaches to measles virus (MV) vaccine development are critical to interrupt the spread of MV. In this study, we report the results using a DNA vaccine expressing a fusion of the measles hemagglutinin...

journal_title：Vaccine

authors： Green TD,Newton BR,Rota PA,Xu Y,Robinson HL,Ross TM

更新日期：2001-10-12 00:00:00

abstract：BACKGROUND AND AIM:Evidence is accumulating that several markers in the human leukocyte antigen (HLA) region have been associated with decreased or increased antibody response to hepatitis B vaccine in different individuals. This meta-analysis is to assess the associations of HLA class II DRB1 and DQB1 alleles with imm...

journal_title：Vaccine

authors： Li ZK,Nie JJ,Li J,Zhuang H

更新日期：2013-09-13 00:00:00

abstract：:In future, a policy of "vaccinate-to-live" may be included in the repertoire of foot-and-mouth disease (FMD) control measures and in support of this approach, we have investigated the hypothesis that vaccine-induced reduction in virus replication and excretion from pigs can be correlated to the severity of clinical si...

journal_title：Vaccine

authors： Parida S,Fleming L,Oh Y,Mahapatra M,Hamblin P,Gloster J,Doel C,Gubbins S,Paton DJ

更新日期：2007-11-07 00:00:00

abstract：:A substantial rise in the number of AIDS cases has been observed during the past year in many African countries, and HIV-2 indigenous transmission and increased disease have since gained importance in Senegal. Both for HIV-1 and HIV-2 diagnosis, ELISA positivity is followed by a Western blot test for specific antibodi...

journal_title：Vaccine

authors： Arya SC

更新日期：1988-06-01 00:00:00

abstract：:Clinical leprosy is characterized by varying manifestations between tuberculoid and lepromatous leprosy. In the former state the patient is able to elicit a cell-mediated immune response whereas in the latter, there is usually a humoral response. An understanding of this immunological balance is crucial in the search ...

journal_title：Vaccine

authors： Stewart-Tull DE

更新日期：1984-12-01 00:00:00

abstract：:A gene encoding the mature Escherichia coli heat-labile enterotoxin B subunit (LTB) was introduced in a vector pNU212 and expressed at high levels in Bacillus brevis HPD31. The maximum amount of recombinant LTB (rLTB) secreted into the modified 5PY medium containing erythromycin was about 350 mg l(-1) when cultivated ...

journal_title：Vaccine

authors： Kozuka S,Yasuda Y,Isaka M,Masaki N,Taniguchi T,Matano K,Moriyama A,Ohkuma K,Goto N,Udaka S,Tochikubo K

更新日期：2000-03-06 00:00:00

abstract：:To prevent premature dismissal of promising vaccine programs, it is critical to determine if lack of efficacy in the field is due to allele specific-efficacy, rather than to the lack of immunogenicity of the candidate antigen. Here we use samples collected during a field trial of the AMA1-based FMP2.1/AS02A malaria va...

journal_title：Vaccine

authors： Ouattara A,Niangaly A,Adams M,Coulibaly D,Kone AK,Traore K,Laurens MB,Tolo Y,Kouriba B,Diallo DA,Doumbo OK,Plowe CV,Djimdé A,Thera MA,Laufer MK,Takala-Harrison S,Silva JC

更新日期：2020-07-31 00:00:00

abstract：:We demonstrated earlier that immunization with recombinant Leptospira immunoglobulin like protein A (LigA) induced significant protection against virulent Leptospira interrogans serovar Pomona challenge in hamsters. However, the protective immune mechanism remains unclear. In the present study we demonstrated the prot...

journal_title：Vaccine

authors： Faisal SM,Yan W,Chen CS,Palaniappan RU,McDonough SP,Chang YF

更新日期：2008-01-10 00:00:00

abstract：:The frequent outbreak of respiratory infectious diseases such as influenza and pulmonary tuberculosis calls for new immunization strategies with high effectiveness. Nasal immunization is one of the most potential methods to prevent the diseases infected through the respiratory tract. In this study, we designed a water...

journal_title：Vaccine

authors： Liu Q,Zhang C,Zheng X,Shao X,Zhang X,Zhang Q,Jiang X

更新日期：2014-05-07 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is the major viral cause of infant and childhood lower respiratory tract disease worldwide. Defining the optimal target product profile (TPP) is complicated due to a wide range of possible vaccine properties, modalities and an incomplete understanding of the mechanism of nat...

journal_title：Vaccine

authors： Pan-Ngum W,Kinyanjui T,Kiti M,Taylor S,Toussaint JF,Saralamba S,Van Effelterre T,Nokes DJ,White LJ

更新日期：2017-01-05 00:00:00

abstract：:Generating broadly neutralizing antibodies with candidate vaccines has remained an elusive goal. Consequently, vaccine candidates developed have aimed at eliciting cell-mediated immune effector activities (CMI) that could delay disease progression, and maybe also limit secondary transmission, by controlling virus repl...

journal_title：Vaccine

authors： Gurunathan S,Habib RE,Baglyos L,Meric C,Plotkin S,Dodet B,Corey L,Tartaglia J

更新日期：2009-03-23 00:00:00

abstract：:Measles, mumps and rubella (MMR) vaccination coverage in Italy has been decreasing starting from 2012 and, at the present, none of the Italian regions has achieved the goal of 95% coverage target. A decision of the Court of Justice of Rimini in March 2012 that awarded vaccine-injury compensation for a case of autism h...

journal_title：Vaccine

authors： Aquino F,Donzelli G,De Franco E,Privitera G,Lopalco PL,Carducci A

更新日期：2017-08-16 00:00:00

abstract：OBJECTIVE:To evaluate whether the social media strategy developed for the campaign Stop HPV - stop cervical cancer was successful at engaging target groups in communication regarding HPV vaccination. INTRODUCTION:In 2009, the Human Papillomavirus (HPV) vaccine became part of the Danish childhood vaccination program to...

journal_title：Vaccine

authors： Pedersen EA,Loft LH,Jacobsen SU,Søborg B,Bigaard J

更新日期：2020-06-26 00:00:00

abstract：:To evaluate the safety and immunogenicity of a diphtheria, tetanus, acellular pertussis and Haemophilus infuenzae Type b (DTaP/Hib) combination vaccine first developed by a Chinese manufacturer, a randomized, two-stage, parallel controlled, single center clinical trial was conducted in Dafeng, Jiangsu Province of Chin...

journal_title：Vaccine

authors： Li G,Zhang H,Zhou W,Ye Q,Li F,Wang H,Hou Q,Xu Y,Ma X,Tan Y,Wang L,Li Y,Li H,Meng F,Liang Q,Liu A,Qin C,Wei W,Liu J,Ruan C,Tao W,Zhang S,Zheng H,Zhu F

更新日期：2010-06-07 00:00:00

abstract：:Gram-negative bacterial outer membrane proteins (Omps) have an important role in pathogenesis and signal reception. We previously reported that Acinetobacter OmpA (AbOmpA) induced maturation of bone marrow-derived dendritic cells (BMDCs) and that AbOmpA-primed DCs produced IL-12 which generated Th1 CD4(+) T-cells. We ...

journal_title：Vaccine

authors： Jang MJ,Kim JE,Chung YH,Lee WB,Shin YK,Lee JS,Kim D,Park YM

更新日期：2011-03-16 00:00:00

abstract：:Clinical trials with pandemic influenza vaccine candidates have focused on aluminium hydroxide as an adjuvant to boost humoral immune responses. In this study we investigated the effect of aluminium hydroxide on the magnitude and type of immune response induced by whole-inactivated virus (WIV) vaccine. Balb/c mice wer...

journal_title：Vaccine

authors： Bungener L,Geeraedts F,Ter Veer W,Medema J,Wilschut J,Huckriede A

更新日期：2008-05-02 00:00:00

abstract：:On July 9, 2014, Aeras and the Max Planck Institute for Infection Biology convened a workshop entitled "Whole Mycobacteria Cell Vaccines for Tuberculosis" at the Max Planck Institute for Infection Biology on the grounds of the Charité Hospital in Berlin, Germany, close to the laboratory where, in 1882, Robert Koch fir...

journal_title：Vaccine

authors： Whole Mycobacteria Cell Vaccines for Tuberculosis Summary Group.

更新日期：2015-06-12 00:00:00

abstract：BACKGROUND:During the past decade, in the United States, an increasing number of hepatitis B outbreaks have been reported in assisted living facilities (ALFs) as a result of breaches in infection control practices. We evaluated the seroprotection rates conferred by hepatitis B vaccine among older adults during a respon...

journal_title：Vaccine

authors： Tohme RA,Awosika-Olumo D,Nielsen C,Khuwaja S,Scott J,Xing J,Drobeniuc J,Hu DJ,Turner C,Wafeeg T,Sharapov U,Spradling PR

更新日期：2011-11-21 00:00:00

abstract：:Livestock production is a fundamental source of revenue and nutrition, wherein cattle-farming constitutes one of the major agricultural industries. Vectors and vector-borne diseases constitute one of the major factors that decrease the livelihood of all farming communities, more so in resource-poor communities and dev...

journal_title：Vaccine

authors： Robbertse L,Richards SA,Stutzer C,Olivier NA,Leisewitz AL,Crafford JE,Maritz-Olivier C

更新日期：2020-10-14 00:00:00

abstract：:Previous noninvasive vaccine submission approaches including respiratory tract-based methods are limited to specific pathogens. Recent developments on ultrasound biology suggest that ultrasound-mediated molecule submission (sonoporation) could be an effective noninvasive approach for gene therapy as well as drug submi...

journal_title：Vaccine

authors： Yuan TF

更新日期：2008-08-05 00:00:00

abstract：BACKGROUND:Despite its high worldwide morbidity and mortality, there is yet no licensed vaccine for shigellosis. We reported the safety and immunogenicity of Shigella O-specific polysaccharide-protein conjugates in adults and young children and efficacy of Shigella sonnei conjugate in young adults. METHODS:A double-bl...

journal_title：Vaccine

authors： Passwell JH,Ashkenazi S,Banet-Levi Y,Ramon-Saraf R,Farzam N,Lerner-Geva L,Even-Nir H,Yerushalmi B,Chu C,Shiloach J,Robbins JB,Schneerson R,Israeli Shigella Study Group.

更新日期：2010-03-02 00:00:00

abstract：:The objective of the present study was to investigate the feasibility of a subunit vaccine and a live bacteria vaccine to protect chickens against infectious bursal disease virus (IBDV) infection. The gene for VP2 of a new wild-type very virulent IBDV (vvIBDV) strain was cloned into an Escherichia coli expression syst...

journal_title：Vaccine

authors： Rong J,Cheng T,Liu X,Jiang T,Gu H,Zou G

更新日期：2005-09-23 00:00:00

abstract：:The severe acute respiratory syndrome coronavirus nucleocapsid protein (SARS-CoV N) is one of the major targets for SARS vaccine due to its high potency in triggering immune responses. In this study, we have identified a novel HLA-A*0201 restricted epitope, N220 (LALLLLDRL), of the SARS-CoV N-protein through bioinform...

journal_title：Vaccine

authors： Cheung YK,Cheng SC,Sin FW,Chan KT,Xie Y

更新日期：2007-08-10 00:00:00

abstract：:Measles virus (MV) vaccine strains use CD46, signaling lymphocyte activation molecule, and nectin-4 in human cells as receptors. Meanwhile, many of them are propagated in primary chicken embryonic fibroblasts (CEFs). Our data revealed that CEFs express a nectin-4 homologous molecule (CEF nectin-4) containing well-cons...

journal_title：Vaccine

authors： Seki F,Someya K,Komase K,Takeda M

更新日期：2016-01-02 00:00:00

abstract：:In anticipation of the implementation of new prophylactic HPV vaccines, the WHO is supporting the establishment of a global WHO HPV Laboratory Network whose mission is to "contribute to improving the quality of laboratory services for effective surveillance and monitoring of HPV vaccination impact through enhanced, st...

journal_title：Vaccine

authors： Ferguson M,Wilkinson DE,Zhou T

更新日期：2009-01-14 00:00:00

abstract：:Chlamydia trachomatis causes respiratory and sexually transmitted infections. Here, we tested a vaccine formulated with the recombinant major outer membrane protein from C. trachomatis mouse pneumonitis (CT-MoPn) for its ability to protect mice against an intranasal (i.n.) challenge. The adjuvants CpG and Montanide we...

journal_title：Vaccine

authors： Ralli-Jain P,Tifrea D,Cheng C,Pal S,de la Maza LM

更新日期：2010-11-10 00:00:00

abstract：:Peptidoglycan monomer (PGM) originating from Brevibacterium divaricatum is a non-toxic, non-pyrogenic, water-soluble immunostimulator. It potentiates humoral immune response to ovalbumin (OVA) in mice upregulating both immunoglobulin (IgG) 1 and IgG2a antibody subclasses. This study concerns the influence of PGM on T ...

journal_title：Vaccine

authors： Halassy Spoljar B,Cimbora T,Hanzl-Dujmović I,Dojnović B,Sabioncello A,Krstanović M,Tomasić J

更新日期：2002-10-04 00:00:00

abstract：:A catch-up campaign targeting children aged 8-16 years using measles-rubella (MR) vaccine was conducted during 2001 in Korea. To evaluate the impact of the campaign and assess mumps immunity, human IgG antibodies were detected using ELISA for measles (5826 samples) and mumps (5890 samples) in a national sample of oppo...

journal_title：Vaccine

authors： Kim SS,Han HW,Go U,Chung HW

更新日期：2004-12-02 00:00:00