Prophylactic and therapeutic efficacy of the epitope vaccine CTB-UA against Helicobacter pylori infection in a BALB/c mice model.

abstract：:Reducing the enzyme loadings for enzymatic saccharification of lignocellulose is required for economically feasible production of biofuels and biochemicals. One strategy is addition of small amounts of synergistic proteins to cellulase mixtures. Synergistic proteins increase the activity of cellulase without causing s...

journal_title：Applied microbiology and biotechnology

authors： Kim IJ,Lee HJ,Choi IG,Kim KH

更新日期：2014-10-01 00:00:00

abstract：:Biosurfactant rhamnolipids have been claimed to show biological activities of inhibiting the proliferation of cancer cells. In this study, the cytotoxicity of rhamnolipids was examined on four cancer cells (HepG2, Caco-2, Hela, MCF-7 cells) and two normal cells (HK-2 cell, primary hepatocyte). Interestingly, both canc...

journal_title：Applied microbiology and biotechnology

authors： Jiang L,Shen C,Long X,Zhang G,Meng Q

更新日期：2014-12-01 00:00:00

abstract：:L-Ribose is a rare and expensive sugar that can be used as a precursor for the production of L-nucleoside analogues, which are used as antiviral drugs. In this work, we describe a novel way of producing L-ribose from the readily available raw material L-arabinose. This was achieved by introducing L-ribose isomerase ac...

journal_title：Applied microbiology and biotechnology

authors： Helanto M,Kiviharju K,Granström T,Leisola M,Nyyssölä A

更新日期：2009-05-01 00:00:00

abstract：:The main objective of this work was the optimization of the production of the beta-ketolase, acetopyruvate hydrolase, from Pseudomonas putida O1. Orcinol was used as an inducer for enzyme production. The growth medium was optimized in two steps. In the first step, screening for optimal glucose concentration was perfor...

journal_title：Applied microbiology and biotechnology

authors： Hofer H,Mandl T,Steiner W

更新日期：2002-11-01 00:00:00

abstract：:Yeast is widely used in the baking, biocontrol, brewing, and bio manufacturing industries. In the baking industry alone, around two million tons of yeast are consumed worldwide every year. While yeast brings delicious and healthy lives to humans, we find that stress resistance of yeast is essential for the development...

journal_title：Applied microbiology and biotechnology

authors： Qiu X,Zhang J,Zhou J,Fang Z,Zhu Z,Li J,Du G

更新日期：2019-08-01 00:00:00

abstract：:The impact of glucose on glycerol metabolism, especially on 3-hydroxypropionaldehyde (3-HPA) accumulation by resting cells of Lactobacillus reuteri has been investigated. Two systems were used in the study: MRS(-) (modified MRS - omitting glucose, acetate and Tween 80) and distilled water (H(2)O). In MRS(-), addition ...

journal_title：Applied microbiology and biotechnology

authors： Lüthi-Peng Q,Dileme FB,Puhan Z

更新日期：2002-07-01 00:00:00

abstract：:Two-stage technologies have been developed for anaerobic digestion of waste-activated sludge. In this study, the archaeal and bacterial community structure dynamics and bioprocess performance of a bench-scale two-stage anaerobic digester treating urban sewage sludge have been studied by the means of high-throughput se...

journal_title：Applied microbiology and biotechnology

authors： Gonzalez-Martinez A,Garcia-Ruiz MJ,Rodriguez-Sanchez A,Osorio F,Gonzalez-Lopez J

更新日期：2016-07-01 00:00:00

abstract：:The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel β-coronavirus, is the main pathogenic agent of the rapidly spreading pneumonia called coronavirus disease 2019 (COVID-19). SARS-CoV-2 infects much more people, especially the elder population, around the world than other coronavirus, such as SAR...

journal_title：Applied microbiology and biotechnology

authors： Chen X,Liao B,Cheng L,Peng X,Xu X,Li Y,Hu T,Li J,Zhou X,Ren B

更新日期：2020-09-01 00:00:00

abstract：:Environmental research delivers valuable bacterial resources for biotechnology. We believe that systematic long-term preservation of bacteria will promote future biotechnological innovations, by safeguarding the accessibility of bacteria already recognized to have interesting features and providing a "pool" of bacteri...

journal_title：Applied microbiology and biotechnology

authors： Heylen K,Hoefman S,Vekeman B,Peiren J,De Vos P

更新日期：2012-05-01 00:00:00

abstract：:Aptamers are single-stranded nucleic acids or peptides identified from a randomized combinatorial library through specific interaction with the target of interest. Targets can be of any size, from small molecules to whole cells, attesting to the versatility of aptamers for binding a wide range of targets. Aptamers sho...

journal_title：Applied microbiology and biotechnology

authors： Gopinath SC,Lakshmipriya T,Chen Y,Arshad MK,Kerishnan JP,Ruslinda AR,Al-Douri Y,Voon CH,Hashim U

更新日期：2016-08-01 00:00:00

abstract：:Biobutanol can be indigenously synthesized by solventogenic Clostridium species; however, these microorganisms possess inferior capability of utilizing abundant and renewable organic wastes, such as starch, lignocellulose, and even syngas. The common strategy to achieve direct butanol production from these organic was...

journal_title：Applied microbiology and biotechnology

authors： Jiang Y,Zhang T,Lu J,Dürre P,Zhang W,Dong W,Zhou J,Jiang M,Xin F

更新日期：2018-07-01 00:00:00

abstract：:A mixed methane-oxidizing biofilm was characterized, concurrently using a number of advanced techniques. Community analysis results by microarray exhibited that type II members dominated the methanotrophic community, in which Methylocystis was most abundant, followed by Methylosinus. Observation results by fluorescent...

journal_title：Applied microbiology and biotechnology

authors： Kim TG,Yi T,Lee EH,Ryu HW,Cho KS

更新日期：2012-08-01 00:00:00

abstract：:Heterologous biosynthesis of tetrahydrocannabinolic acid (THCA) in yeast is a biotechnological process in Natural Product Biotechnology that was recently introduced. Based on heterologous genes from Cannabis sativa and Streptomyces spp. cloned into Saccharomyces cerevisiae, the heterologous biosynthesis was fully embe...

journal_title：Applied microbiology and biotechnology

authors： Thomas F,Schmidt C,Kayser O

更新日期：2020-11-01 00:00:00

abstract：:Acid tolerance and aroma profile are crucial factors for wine production in Saccharomyces cerevisiae. However, most wine yeasts to date fail to endure low-pH environments, therefore resulting in problems such as lengthened fermentation and poor flavor during acidic fruit wine production. In the present study, we estab...

journal_title：Applied microbiology and biotechnology

authors： Tian T,Wu D,Ng CT,Yang H,Sun J,Liu J,Lu J

更新日期：2020-04-01 00:00:00

abstract：:The efficient fermentation of xylose can improve biofuel production. We previously developed a two-stage transcriptional reprogramming (TSTR) strategy (including a glucose fermentation stage and a xylose fermentation stage) and demonstrated its application for the construction of Saccharomyces cerevisiae strains with ...

journal_title：Applied microbiology and biotechnology

authors： Zhang X,Wang J,Zhang W,Hou JY,Xiao W,Cao L

更新日期：2018-08-01 00:00:00

abstract：:Steroid phosphate esters are very rare natural lipids that have been comparatively recently isolated from fractions of polar lipids of marine sponges and starfish. These steroids exhibit interesting biological activities. When using the PASS computer program, we showed that many of steroid phosphate esters showed anti...

journal_title：Applied microbiology and biotechnology

authors： Dembitsky VM,Gloriozova TA,Savidov N

更新日期：2018-09-01 00:00:00

abstract：:The Gram-positive Corynebacterium glutamicum is widely used for fermentative production of amino acids. The world production of L-lysine has surpassed 2 million tons per year. Glucose uptake and phosphorylation by C. glutamicum mainly occur by the phosphotransferase system (PTS) and to lesser extent by inositol permea...

journal_title：Applied microbiology and biotechnology

authors： Pérez-García F,Peters-Wendisch P,Wendisch VF

更新日期：2016-09-01 00:00:00

abstract：:The process of succinic acid (SA) production represents the combination of microbial synthesis of α-ketoglutaric acid from rapeseed oil by yeast Yarrowia lipolytica VKM Y-2412 and subsequent decarboxylation of α-ketoglutaric acid by hydrogen peroxide to SA that leads to the production of 69.0 g l(-1) of SA and 1.36 g ...

journal_title：Applied microbiology and biotechnology

authors： Kamzolova SV,Vinokurova NG,Dedyukhina EG,Samoilenko VA,Lunina JN,Mironov AA,Allayarov RK,Morgunov IG

更新日期：2014-05-01 00:00:00

abstract：:A Saccharomyces-cerevisiae-based simultaneous saccharification and fermentation (SSF) of lignocellulosic biomass is limited to an operating temperature of about 37 degrees C, and even a small increase in temperature can have a deleterious effect. This points to a need for a more thermotolerant yeast. To this end, S. c...

journal_title：Applied microbiology and biotechnology

authors： Kadam KL,Schmidt SL

更新日期：1997-12-01 00:00:00

abstract：:Poly(butanediol succinate) (PBS), a biodegradable polymer, was used as both solid carbon source and biofilm carrier for biological nitrate removal process, in which PBS was filled in a packed-bed bioreactor. The denitrification performance and the microbial diversity of biofilm attached on the surface of PBS were inve...

journal_title：Applied microbiology and biotechnology

authors： Shen Z,Yin Y,Wang J

更新日期：2016-07-01 00:00:00

abstract：:Transcription factors have been studied as an important drug candidate. Ever since the successful generation of induced pluripotent stem cells (iPSCs), there has been tremendous interest in reprogramming transcription factors. Because of the safety risks involved in a virus-based approach, many researchers have been t...

journal_title：Applied microbiology and biotechnology

authors： Ryu J,Park HH,Park JH,Lee HJ,Rhee WJ,Park TH

更新日期：2016-04-01 00:00:00

abstract：:In this work, fermentation and formulation aspects of the nematophagous fungus Hirsutella rhossiliensis BBA were investigated. When incubated in 2% (w/w) glucose and 0.5% (w/w) yeast extract medium in a 1-L Erlenmeyer flask without baffles, heavy pellet formation was observed. Only 40% of the mycelium had a size less ...

journal_title：Applied microbiology and biotechnology

authors： Patel AV,Jakobs-Schönwandt D,Rose T,Vorlop KD

更新日期：2011-03-01 00:00:00

abstract：:Saccharomyces cerevisiae was transformed with the Pichia stipitis CBS 6054 XYL1 and XYL2 genes encoding xylose reductase (XR) and xylitol dehydrogenase (XDH) respectively. The XYL1 and XYL2 genes were placed under the control of the alcohol dehydrogenase 1 (ADH1) and phosphoglycerate kinase (PGK1) promoters in the yea...

journal_title：Applied microbiology and biotechnology

authors： Walfridsson M,Anderlund M,Bao X,Hahn-Hägerdal B

更新日期：1997-08-01 00:00:00

abstract：:In industry, filamentous fungi have a prominent position as producers of economically relevant primary or secondary metabolites. Particularly, the advent of genetic engineering of filamentous fungi has led to a growing number of molecular tools to adopt filamentous fungi for biotechnical applications. Here, we summari...

journal_title：Applied microbiology and biotechnology

authors： Kluge J,Terfehr D,Kück U

更新日期：2018-08-01 00:00:00

abstract：:The cultivated and uncultivated bacterial communities of an activated sludge plant were studied. Two samples were taken and a total of 516 bacterial isolates were classified into groups using their whole-cell protein patterns. The distribution of bacteria into protein-pattern groups differed significantly between the ...

journal_title：Applied microbiology and biotechnology

authors： Vainio EJ,Moilanen A,Koivula TT,Bamford DH,Hantula J

更新日期：1997-07-01 00:00:00

abstract：:Red koji or red mold rice is prepared by growing a genus Monascus on steamed rice. For centuries, it has been used in Asia for the production of fermented foods including red rice wine and fermented tofu. Although red koji is an important source of various hydrolytic enzymes critical for food fermentation, information...

journal_title：Applied microbiology and biotechnology

authors： Yasuda M,Tachibana S,Kuba-Miyara M

更新日期：2012-10-01 00:00:00

abstract：:Production of volatile sulphur compounds (VSC) was assessed in culture media supplemented with L-methionine or L-methionine/L-cysteine mixtures, using five cheese-ripening yeasts: Debaryomyces hansenii DH47(8), Kluyveromyces lactis KL640, Geotrichum candidum GC77, Yarrowia lipolytica YL200 and Saccharomyces cerevisiae...

journal_title：Applied microbiology and biotechnology

authors： López Del Castillo-Lozano M,Delile A,Spinnler HE,Bonnarme P,Landaud S

更新日期：2007-07-01 00:00:00

abstract：:Cyanophycin is non-ribosomally synthesized protein-like copolymer. Synthesis of cyanophycin is catalyzed by cyanophycin synthetase (CphA). In this study, a novel cyanophycin synthetase CphA49 belonging to NOR5 clade of Gammaproteobacteria was identified with primer-based screening from a deep-sea sediment metagenomic ...

journal_title：Applied microbiology and biotechnology

authors： Du J,Li L,Ding X,Hu H,Lu Y,Zhou S

更新日期：2013-10-01 00:00:00

abstract：:Shikimic acid is an industrially important chiral compound used as a key ingredient in formulation of drug Oseltamivir phosphate (Tamiflu) for the treatment of swine/avian flu. The high cost and limited availability of shikimic acid isolated from plants has detained the use of this valuable building block of the drug....

journal_title：Applied microbiology and biotechnology

authors： Rawat G,Tripathi P,Saxena RK

更新日期：2013-05-01 00:00:00

abstract：:The production of the anticoagulant drug heparin from non-animal sources has a number of advantages over the current commercial production of heparin. These advantages include better source material availability, improved quality control, and reduced concerns about animal virus or prion impurities. A bioengineered hep...

journal_title：Applied microbiology and biotechnology

authors： Wang Z,Yang B,Zhang Z,Ly M,Takieddin M,Mousa S,Liu J,Dordick JS,Linhardt RJ

更新日期：2011-07-01 00:00:00