Lung aerosol deposition in suckling infants.

abstract：:Tuberculosis rarely presents in the neonatal period. Though treatable, it may be fatal despite modern treatment. The diagnosis of congenital tuberculosis should be considered in any neonate with pneumonia that fails to respond to conventional treatment, particularly in a child from an ethnic or socioeconomic environme...

journal_title：Archives of disease in childhood

authors： Bate TW,Sinclair RE,Robinson MJ

更新日期：1986-05-01 00:00:00

abstract：:When prescribing drugs for children, it is fundamental to acknowledge that they are distinct from adults with a different physiology and metabolism. They are also still maturing. The development of drugs with a primarily paediatric indication thus requires the trialling of these drugs in a paediatric population to ass...

journal_title：Archives of disease in childhood

authors： Prasad S

更新日期：2005-02-01 00:00:00

abstract：AIMS:To investigate socioeconomic inequalities in the risk of congenital anomalies, focusing on risk of specific anomaly subgroups. METHODS:A total of 858 cases of congenital anomaly and 1764 non-malformed control births were collected between 1986 and 1993 from four UK congenital malformation registers, for the purpo...

journal_title：Archives of disease in childhood

authors： Vrijheid M,Dolk H,Stone D,Abramsky L,Alberman E,Scott JE

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Cerebral venous sinus thrombosis (CVST) in children is associated with a high incidence of serious morbidity and mortality. The presenting features are variable. It can be diagnostically challenging and the optimal treatment is uncertain. AIM:To describe the features of a series of children with CVST treate...

journal_title：Archives of disease in childhood

authors： Mallick AA,Sharples PM,Calvert SE,Jones RW,Leary M,Lux AL,O'Callaghan FJ,Osborne JP,Patel JS,Prendiville AT,Renowden S,Jardine PE

更新日期：2009-10-01 00:00:00

abstract：AIM:To determine the outcome and identify predictive factors in children with psychogenic non-epileptic seizures (PNES). METHOD:The biographies of 35 children with PNES, attending a tertiary paediatric neurology centre, were reviewed. RESULTS:Thirty five children attending the department between 1987 and 1997 were ev...

journal_title：Archives of disease in childhood

authors： Irwin K,Edwards M,Robinson R

更新日期：2000-06-01 00:00:00

abstract：:Malaria, as a key disease of poverty, was singled out for special attention in the Millennium Project of 2000. Recent data suggest that malaria incidence and mortality are now declining all over the world. While these figures are cause for celebration, they must be interpreted carefully and with caution, particularly ...

journal_title：Archives of disease in childhood

authors： Owens S

更新日期：2015-02-01 00:00:00

abstract：AIM:Childhood arthritis arises from several causes. The aim of this observational study is to compare the clinical and biological features and short-term outcome of different types of arthritis because they have different treatment and prognoses. METHODS:Children <16 years of age hospitalised in a French tertiary care...

journal_title：Archives of disease in childhood

authors： Aupiais C,Basmaci R,Ilharreborde B,Blachier A,Desmarest M,Job-Deslandre C,Faye A,Bonacorsi S,Alberti C,Lorrot M

更新日期：2017-04-01 00:00:00

abstract：:Copper deficiency is reported in an infant of very low birthweight. It was characterised by extensive bone changes, severe neutropenia, and hypocupraemia. These manifestations could have been missed but for an intercurrent pneumonia which led to an x-ray of the chest. ...

journal_title：Archives of disease in childhood

authors： Yuen P,Lin HJ,Hutchinson JH

更新日期：1979-07-01 00:00:00

abstract：:Total DNA was estimated in the lungs of 80 fetuses and newborn infants varying in gestation from 14 weeks to term. In fetuses of appropriate weight for gestational age total lung DNA increased at a constant rate from about 35 mg at 17 weeks' gestation to 480 mg at term. The lungs of immature fetuses were heavier and c...

journal_title：Archives of disease in childhood

authors： Wigglesworth JS,Desai R

更新日期：1981-08-01 00:00:00

abstract：OBJECTIVE:Obesity is considered a polygenic and multifactorial disorder and different single nucleotide polymorphisms (SNP) are involved. Studies concerning their impact on weight loss in lifestyle intervention are scarce. METHODS:The effect of two different SNP (INSIG2: rs7566605, FTO: rs9939609) was analysed on the ...

journal_title：Archives of disease in childhood

authors： Reinehr T,Hinney A,Toschke AM,Hebebrand J

更新日期：2009-12-01 00:00:00

abstract：:During June and July 1977 5 junior boys in a boarding school for 800 pupils became ill with a mild infection caused by Coxsackie B1. The school had been taking part in a vaccine trial, and paired blood samples had been taken from new entrants in October 1976 and October 1977. 18% of the boys susceptible to the infecti...

journal_title：Archives of disease in childhood

authors： Hoskins TW,Davies JR,Smith AJ,Collingham K,Chamberlain RN

更新日期：1979-04-01 00:00:00

abstract：:A retrospective study of Scottish hospital inpatients aged 15 years or less has revealed, over a 4-year period, 36 cases of venous thrombosis or phlebitis. Of these 10 were considered to have deep venous thrombosis; 2 cases were associated with obvious pulmonary embolism and 2 cases developed chronic venous insufficie...

journal_title：Archives of disease in childhood

authors： Jones DR,Macintyre IM

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:In volume guarantee ventilation with the Dräger Babylog 8000 ventilator, inspiratory and expiratory flows are monitored and the expiratory tidal volume calculated following each inflation. The pressure for the next inflation is modified to ensure the expired tidal volume is close to the set value. AIM:To in...

journal_title：Archives of disease in childhood

authors： McCallion N,Lau R,Dargaville PA,Morley CJ

更新日期：2005-08-01 00:00:00

abstract：:The frequency of negative hydrogen breath tests due to colonic bacterial flora which are unable to produce hydrogen was determined after oral lactulose challenge in 98 healthy Dutch schoolchildren. There was a negative result in 9.2%. The probability of a false normal lactose breath test (1:77) was calculated from the...

journal_title：Archives of disease in childhood

authors： Douwes AC,Schaap C,van der Klei-van Moorsel JM

更新日期：1985-04-01 00:00:00

abstract：:The characteristics of nine children with community acquired pneumonia with evidence of Streptococcus pneumoniae and Mycoplasma pneumoniae coinfection are described. ...

journal_title：Archives of disease in childhood

authors： Toikka P,Juvén T,Virkki R,Leinonen M,Mertsola J,Ruuskanen O

更新日期：2000-11-01 00:00:00

abstract：:Flow velocities in the basal cerebral arteries were studied by transcranial Doppler sonography. A longitudinal study was undertaken on 25 healthy newborn babies during the first 20 days of life, and a cross sectional study was performed on 112 healthy children between 1 day and 18 years of age. A rapid linear increase...

journal_title：Archives of disease in childhood

authors： Bode H,Wais U

更新日期：1988-06-01 00:00:00

abstract：:A postal survey of recently appointed consultant paediatricians was undertaken to determine whether they perceived their training had adequately equipped them for their current job. The response rate was 69% (207/299). After excluding replies from consultants trained outside the UK the analysis was carried out on 167 ...

journal_title：Archives of disease in childhood

authors： Lenton SW,Dison PJ,Haines LC

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:The number of trips to the tropics taken by children with chronic health disorders (CHDs) is increasing. METHODS:All of the children with CHDs who attended two international vaccination centres in France before travelling to the tropics were included in a prospective, exposed/unexposed study. Each child was...

journal_title：Archives of disease in childhood

authors： Ducrocq C,Sommet J,Levy D,Trieu TV,Quercia F,Morin L,Belletre X,Koehl B,Sorge F,Alberti C,de Pontual L,Faye A

更新日期：2016-11-01 00:00:00

abstract：:Ketamine hydrochloride 2 mg/kg, together with atropine 0.2 mg, has been given intravenously on 100 occasions on a general paediatric ward. No serious side effects occurred. Dreams followed in 4 children but did not reduce acceptability of the drug. In our hands it has greatly reduced the pain and distress of children ...

journal_title：Archives of disease in childhood

authors： Elliott E,Hanid TK,Arthur LJ,Kay B

更新日期：1976-01-01 00:00:00

abstract：AIMS:To review the results of long term high dose intravenous immunoglobulin treatment. METHODS:162 treatment years in 18 patients with hypogammaglobulinaemia who received intravenous immunoglobulin treatment between 1973 and 1993 were reviewed. RESULTS:A mean dose of 0.42 g/kg immunoglobulin resulted in a mean troug...

journal_title：Archives of disease in childhood

authors： Skull S,Kemp A

更新日期：1996-06-01 00:00:00

abstract：:Twenty two babies who developed bronchopulmonary dysplasia were compared with 22 babies matched for gestational age who did not. Those with bronchopulmonary dysplasia weighed less at birth and had lower energy intakes from day 7 to day 56. Undernutrition before and after birth is a major problem in babies who develop ...

journal_title：Archives of disease in childhood

authors： Wilson DC,McClure G,Halliday HL,Reid MM,Dodge JA

更新日期：1991-01-01 00:00:00

abstract：:Plasma amino acids were measured in 35 preterm infants, of whom 11 weighed less than 1000 g and 24 weighed between 1000 g and 1500 g at the time of sampling. Repeat samples were obtained in 18 at least seven days later. Seventeen infants were fed with preterm formula milk and 18 with expressed maternal breast milk at ...

journal_title：Archives of disease in childhood

authors： Ventura V,Brooke OG

更新日期：1987-12-01 00:00:00

abstract：:The efficacy of an absorbable antimicrobial agent trimethoprim-sulphamethoxazole (TMP-SMX) in the management of children with persistent diarrhoea was evaluated in a double blind, randomised, and placebo controlled trial. Of the 55 patients studied, 28 received TMP-SMX, and 27 received placebo. A trend in stool weight...

journal_title：Archives of disease in childhood

authors： Alam NH,Bardhan PK,Haider R,Mahalanabis D

更新日期：1995-06-01 00:00:00

abstract：:36 parents of infants who had died suddenly did not differ in frequency of atopic symptoms, immediate skin tests, IgE, IgE antibody, immunoglobulin G, A, and M, or yeast opsonisation, from 36 matched controls, although atopy was common (about half had atopy in both groups. ...

journal_title：Archives of disease in childhood

authors： Warnasuriya N,Downham MA,Skelton A,Turner MW,Soothill JF

更新日期：1980-11-01 00:00:00

abstract：:Three clinically normal sibs were discovered to have type II hyperprolinaemia in a routine serum amino acid screening programme in Sicily. In addition to the basic biochemical features of type II hyperprolinaemia, all 3 children had marked hyperglycinaemia, whereas their parents had both normal blood proline and glyci...

journal_title：Archives of disease in childhood

authors： Pavone L,Mollica F,Levy HL

更新日期：1975-08-01 00:00:00

abstract：:The USA has a long-standing paediatric influenza vaccination programme, including use of live attenuated influenza vaccine (LAIV). Following US evidence of apparent lack of vaccine effectiveness (VE) of LAIV in 2015/2016, particularly against A(H1N1)pdm09, the USA suspended the use of LAIV in the 2016/2017 season. The...

journal_title：Archives of disease in childhood

authors： Pebody R,McMenamin J,Nohynek H

更新日期：2018-01-01 00:00:00

abstract：:Dubowitz et al. have offered a scoring system for estimating the gestational age of newborn babies. If the system is applied to twin pairs, the heavier twin is generally estimated to have a greater gestational age than the lighter one. Previously this has been interpreted as a flaw in the scoring system. However, it m...

journal_title：Archives of disease in childhood

authors： James WH

更新日期：1980-04-01 00:00:00

abstract：:Eight hospitals reported 781 non-iatrogenic accidents occurring to patients and visitors under 16 years of age during an 18 month period up to October 1989. Accidents more often involved boys and children aged 3 to 5 years old. Falls from a height, slips, and striking accidents were common by day and falls by night. A...

journal_title：Archives of disease in childhood

authors： Levene S,Bonfield G

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:A paucity of evidence regarding the natural history of congenital pulmonary airway malformations (CPAMs) and pulmonary sequestration (PS) has resulted in a divergence in management strategy of asymptomatic cases. METHODS:We describe the long-term clinical course of 119 children diagnosed with these lesions ...

journal_title：Archives of disease in childhood

authors： Cook J,Chitty LS,De Coppi P,Ashworth M,Wallis C

更新日期：2017-09-01 00:00:00

abstract：:This study evaluated the accuracy of the interpretation of the chest film in delineating localised abnormalities of ventilation and perfusion, as well as the overall severity of airways obstruction, exercise tolerance, and clinical condition in children with cystic fibrosis. Radiographic findings in various regions of...

journal_title：Archives of disease in childhood

authors： Coates AL,Boyce P,Shaw DG,Godfrey S,Mearns M

更新日期：1981-02-01 00:00:00