Abstract:
:The frequency of negative hydrogen breath tests due to colonic bacterial flora which are unable to produce hydrogen was determined after oral lactulose challenge in 98 healthy Dutch schoolchildren. There was a negative result in 9.2%. The probability of a false normal lactose breath test (1:77) was calculated from these results together with those from a separate group of children with lactose malabsorption (also determined by hydrogen breath test). A study of siblings and mothers of subjects with a negative breath test did not show familial clustering of this condition. Faecal incubation tests with various sugars showed an increase in breath hydrogen greater than 100 parts per million in those with a positive breath test while subjects with a negative breath test also had a negative faecal incubation test. The frequency of a false negative hydrogen breath test was higher than previously reported, but this does not affect the superiority of this method of testing over the conventional blood glucose determination.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Douwes AC,Schaap C,van der Klei-van Moorsel JMdoi
10.1136/adc.60.4.333subject
Has Abstractpub_date
1985-04-01 00:00:00pages
333-7issue
4eissn
0003-9888issn
1468-2044journal_volume
60pub_type
杂志文章abstract::The age at which retinopathy of prematurity was first seen was determined in 143 infants. In all, the initial ophthalmological examination was normal. Birth weights varied from 630 to 2700 g and gestational ages from 24.5 to 40.0 weeks. The median postnatal age at which acute retinopathy of prematurity was first seen ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.61.8.774
更新日期:1986-08-01 00:00:00
abstract::Because the incidence of both neonatal respiratory distress syndrome and neonatal mortality can be reduced by giving corticosteroids to women expected to deliver preterm and by giving surfactant to babies at high risk of developing hyaline membrane disease, we have considered what effects the adoption of one or both o...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.66.7_spec_no.757
更新日期:1991-07-01 00:00:00
abstract:BACKGROUND:Children with type 1 diabetes should be encouraged to participate in physical activity because exercise can benefit insulin sensitivity and improve known risk factors for atherosclerosis. METHODS:Physical activity patterns of 127 children and adolescents with stable type 1 diabetes were investigated by 24 h...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2005.075283
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:The number of children admitted to hospital is increasing year on year, with very short-stay admissions doubling in the last decade. Childhood head injury accounts for half a million emergency department attendances in the UK every year. The National Institute for Health and Care Excellence (NICE) has issued...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2015-308615
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:Early diagnosis and treatment initiation are important factors for successful treatment of mucopolysaccharidosis type I (MPS I). The purpose of this observational study was to assess whether age at diagnosis and time to first treatment for individuals with MPS I have improved over the last 15 years. STUDY DE...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2020-319040
更新日期:2020-11-02 00:00:00
abstract::Ten intubated neonates (weights 0.90 to 2.58 kg) recovering from respiratory disease had lung mechanics, respiratory patterns, and functional residual capacity measured at 0 cmH2O continuous positive airways pressure and then after application of serially increasing levels of external expiratory resistance. At an exte...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.56.11.869
更新日期:1981-11-01 00:00:00
abstract::Thirty seven healthy infants (18 born at full term and 19 preterm) were studied serially with cross sectional and Doppler echocardiography to compare their postnatal circulatory adaptation. Pulmonary artery pressure was assessed by its inverse relationship with the ratio of pulmonary artery time to peak velocity and r...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.65.1_spec_no.24
更新日期:1990-01-01 00:00:00
abstract::We describe a 21 month old male infant who presented with failure to thrive associated with severe hypokalaemia and metabolic acidosis, together with hypomagnesaemia. Evaluation revealed marked renal and probable faecal potassium wasting, distal renal tubular acidosis, mild urinary magnesium wasting, and a normal gast...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.84.6.504
更新日期:2001-06-01 00:00:00
abstract::Twice daily sustained release theophylline gave satisfactory steady serum theophylline concentrations in asthmatic children aged 7 to 14 years. The children showed improvement in symptoms, less frequent waking at night, reduced use of beta agonist inhalers, and improved early morning peak flows while being treated wit...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.59.12.1159
更新日期:1984-12-01 00:00:00
abstract::During a meningococcal (group A) epidemic, 47 Nigerian children with acute meningococcaemia without meningitis were studied. Their mortality rate was 43% compared with 8% during the whole epidemic. Those presenting with coma and shock had a mortality of 93%, but without shock or coma mortality was only 6%. Coma or sho...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.54.1.44
更新日期:1979-01-01 00:00:00
abstract::The case is reported of an infant with hyperammonaemia secondary to severe distal renal tubular acidosis. A clinical association between increased concentrations of ammonia in serum and renal tubular acidosis has not previously been described. In response to acidosis the infant's kidneys presumably increased ammonia s...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.77.5.441
更新日期:1997-11-01 00:00:00
abstract:AIMS:To document the patterns of presentation and outcome of severe anticholinesterase insecticide poisoning in children requiring intensive care. METHODS:Retrospective case note review of all 5541 children admitted to the paediatric intensive care unit (PICU) of a university hospital during the 10 years from January ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.86.5.352
更新日期:2002-05-01 00:00:00
abstract::Patient triggered ventilation was assessed in 14 neonates (gestational age 24-40 weeks). Inspiratory changes in airflow, monitored by a pneumotachograph, were used to trigger the ventilator and this was not associated with complications. Patient triggered ventilation was maintained for up to eight hours (mean duration...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.63.4.394
更新日期:1988-04-01 00:00:00
abstract:AIM:To determine the association between allergic rhinitis, bottle feeding, non-nutritive sucking habits, and malocclusion in the primary dentition. METHODS:Data were collected on 1160 children aged 4-5 years, who had been longitudinally followed since the age of 4 months, when they were admitted to nurseries in a sub...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2005.088484
更新日期:2006-10-01 00:00:00
abstract:AIMS:To investigate whether sagittal synostosis (SS) has consequences for children's mental and psychomotor development, and whether surgery has any impact on this. METHODS:The study involved 28 children with SS who underwent corrective surgery at a mean age of 8.0 (SD 7.16) months, and 28 normal controls. All the chi...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2003.035824
更新日期:2005-04-01 00:00:00
abstract::Samples of saliva (4 in 24 hours), collected at monthly intervals for the first 6 months of life in 8 term infants by their mothers, were analysed for cortisol by radioimmunoassay. Values in the first month were more variable, daily mean values were greater, and amplitudes of variation were greater than in subsequent ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.58.6.454
更新日期:1983-06-01 00:00:00
abstract::Blood pressure (BP) values and the phenomenon of tracking were evaluated in a group of 481 schoolchildren over a nine year period starting at age 6 years. BP values were obtained yearly by taking the mean of two measurements at one visit, measurements were taken by only two observers during the study. For both systoli...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.81.2.169
更新日期:1999-08-01 00:00:00
abstract:AIM:To evaluate gastric emptying in girls with Turner's syndrome to detect if gastrointestinal motor dysfunction was present. SUBJECTS:Thirteen girls (mean age 8.1 years) with Turner's syndrome, seven girls with familial short stature (6.1 years), and eight control girls (7.6 years). METHODS:Gastric emptying studies ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.75.5.440
更新日期:1996-11-01 00:00:00
abstract::Sleep related arterial oxygen desaturation has been described in clinically stable young adults with cystic fibrosis. The incidence and severity of nocturnal oxygen desaturation in children during infective exacerbations and the changes that occur with treatment were examined. Forty five children with proved cystic fi...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.69.2.197
更新日期:1993-08-01 00:00:00
abstract:OBJECTIVE:To determine if exploratory factor analysis can identify subtypes comprising recognisable clinical patterns of the presenting signs and symptoms of children with joint hypermobility syndrome (JHS). PATIENTS:Eighty-nine children with JHS aged 6-16 years. METHODS:Twelve tests comprising anthropometric, muscul...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2013-305304
更新日期:2015-01-01 00:00:00
abstract::Over a two year period 100 infants with histories of wheeze were challenged with nebulised water. They were sedated and lung function measured by total body plethysmography. Thirteen of the 53 infants who developed bronchoconstriction after challenge with nebulised water were given nebulised sodium cromoglycate and re...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.65.4.404
更新日期:1990-04-01 00:00:00
abstract::The effect on deep body temperature of infants co-sleeping (with either or both parents) is investigated in this case control study. Overnight continuous recordings of rectal temperature were made from 34 babies co-sleeping with one or both parents throughout the night and 34 infants matched for age, feeding regimen, ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.75.3.249
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:Long term growth hormone (GH) treatment in children with idiopathic short stature (ISS) results in a relatively small mean gain in final height of 3-9 cm, which may not justify the cost of treatment. As it is unknown whether GH treatment during puberty adds to final height gain, we sought to improve the cost...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.87.3.215
更新日期:2002-09-01 00:00:00
abstract::We describe the results of a prospective study in which 120 women who developed hypertension in the last trimester of pregnancy were randomly allocated in double blind manner to atenolol or placebo. The mean duration of treatment was five weeks. The only difference between groups during the neonatal period was in resp...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.59.11.1061
更新日期:1984-11-01 00:00:00
abstract::The poor prognosis of patients with trisomy 13 has long been accepted and has been ascribed to brain and heart malformations. It has been suggested, however, that the long term survival is better than was previously thought and that cardiac surgery may be justified. This population based study reviews the incidence, a...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.71.4.343
更新日期:1994-10-01 00:00:00
abstract:OBJECTIVE:To establish whether changes of lung transfer for carbon monoxide (TLCO) are related to the phase of IgA nephropathy. METHODS:Respiratory function was tested in 12 children with IgA nephropathy assessed by percutaneous renal biopsy. This was done during acute exacerbations or haematuria-free phases of the di...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章
doi:10.1136/adc.74.3.236
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVES:To investigate outcome, management, and prevention in Munchausen syndrome by proxy, non-accidental poisoning, and non-accidental suffocation. DESIGN:Ascertainment through British Paediatric Surveillance Unit and questionnaires to responding paediatricians. SETTING:The UK and Republic of Ireland, September ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/adc.78.3.217
更新日期:1998-03-01 00:00:00
abstract::When children are considered for participation in research, British and international guidelines suggest that they should provide assent in addition to their parents' consent. However, examination of these guidelines shows there is confusion regarding the concept of assent. Furthermore, the need for assent may cause p...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2011.211342
更新日期:2011-10-01 00:00:00
abstract::Plasma amino acids were measured in 35 preterm infants, of whom 11 weighed less than 1000 g and 24 weighed between 1000 g and 1500 g at the time of sampling. Repeat samples were obtained in 18 at least seven days later. Seventeen infants were fed with preterm formula milk and 18 with expressed maternal breast milk at ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.62.12.1257
更新日期:1987-12-01 00:00:00
abstract:OBJECTIVE:To examine whether behavioural or cognitive sequelae of otitis media with effusion (OME) continue into late childhood and the early teens (11-18 years). SETTING:Data from a large multipurpose birth cohort study: the Dunedin multidisciplinary health and development study. PARTICIPANTS:Around 1000 children fr...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.85.2.91
更新日期:2001-08-01 00:00:00