Hydrogen breath test in schoolchildren.

Abstract:

:The frequency of negative hydrogen breath tests due to colonic bacterial flora which are unable to produce hydrogen was determined after oral lactulose challenge in 98 healthy Dutch schoolchildren. There was a negative result in 9.2%. The probability of a false normal lactose breath test (1:77) was calculated from these results together with those from a separate group of children with lactose malabsorption (also determined by hydrogen breath test). A study of siblings and mothers of subjects with a negative breath test did not show familial clustering of this condition. Faecal incubation tests with various sugars showed an increase in breath hydrogen greater than 100 parts per million in those with a positive breath test while subjects with a negative breath test also had a negative faecal incubation test. The frequency of a false negative hydrogen breath test was higher than previously reported, but this does not affect the superiority of this method of testing over the conventional blood glucose determination.

journal_name

Arch Dis Child

authors

Douwes AC,Schaap C,van der Klei-van Moorsel JM

doi

10.1136/adc.60.4.333

subject

Has Abstract

pub_date

1985-04-01 00:00:00

pages

333-7

issue

4

eissn

0003-9888

issn

1468-2044

journal_volume

60

pub_type

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