Abstract:
:Ketamine hydrochloride 2 mg/kg, together with atropine 0.2 mg, has been given intravenously on 100 occasions on a general paediatric ward. No serious side effects occurred. Dreams followed in 4 children but did not reduce acceptability of the drug. In our hands it has greatly reduced the pain and distress of children undergoing many routine medical procedures, particularly the dread which builds up when these have to be repeated in the same child. It has also produced close to ideal conditions for the operator, and probably increased his efficiency by reducing the emotional strain which occurs when doing painful things to a frightened patient.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Elliott E,Hanid TK,Arthur LJ,Kay Bdoi
10.1136/adc.51.1.56subject
Has Abstractpub_date
1976-01-01 00:00:00pages
56-9issue
1eissn
0003-9888issn
1468-2044journal_volume
51pub_type
杂志文章abstract::A volumetric Doppler technique was used to measure net ductus arteriosus shunt during the first 48 hours of life in 30 infants of less than 33 weeks' gestation, and in 10 full term infants. In the full term infants a left to right shunt of 62 ml/kg/minute (95% confidence limits 43-82) shortly after birth decreased rap...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.62.10.1030
更新日期:1987-10-01 00:00:00
abstract::Concerns have been expressed in recent years about the decline in children's clinical and biomedical research in the UK, and in the paediatric academic workforce. Here I consider the extent to which these concerns are justified, the sweeping changes that have taken place in research funding, governance and organisatio...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2009.178160
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVES:To assess the potential effect of two guideline discharge oxygen saturation (SpO(2)) recommendations (≥90% and ≥94%) in recovering bronchiolitis. METHODS AND PATIENTS:Infants aged up to 18 months requiring therapeutic oxygen for SpO(2) (≤93%) had SpO(2) assessed in air every 2 h. Time from admission to re-e...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2010.205211
更新日期:2012-04-01 00:00:00
abstract::This paper describes 48 children, aged 14 years or less, who met diagnostic criteria for anorexia nervosa modified from Morgan and Russell. The characteristics of the sample (13 boys and 35 girls) are described along with features of the illness, associated family characteristics, treatment in hospital, and a brief de...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/adc.62.2.114
更新日期:1987-02-01 00:00:00
abstract::A method for securing umbilical catheters is described. It has been used successfully in over 350 babies. It is a simple and rapid method that allows for easy repositioning and, unlike some established techniques, has no potential for damage to the preterm baby's skin. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.63.7_spec_no.750
更新日期:1988-07-01 00:00:00
abstract::Blood lead concentrations and body iron status were investigated in 279 children. Blood lead concentrations showed no increase during iron depletion phase (stage I) but markedly increased from the phase of iron deficient erythropoiesis (stage II). Increased blood lead concentrations in anaemic subjects significantly d...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.88.9.791
更新日期:2003-09-01 00:00:00
abstract::Children with cystic fibrosis have variable degrees of exocrine pancreatic insufficiency which, if untreated, is the main cause of fat malabsorption. The impact of pancreatic enzyme supplementation on fat digestion was measured in 41 children with cystic fibrosis, 11 healthy controls, and five children with mucosal di...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.76.4.349
更新日期:1997-04-01 00:00:00
abstract::A standard acid resistant microsphere pancreatic enzyme preparation was compared with identical capsules half filled with mini-tablets of a new high lipase preparation in a randomised double blind crossover study in children with cystic fibrosis. Each patient received his/her usual number of capsules and the same dose...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.68.2.227
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND:Varicella universal vaccination (UV) has been implemented in many countries for several years. Nevertheless, varicella UV remains debated in Europe and few data are available on the real burden of infection. We assessed the burden of varicella in Belgium through analysis of hospitalised cases during a 1-year...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/archdischild-2015-308283
更新日期:2016-01-01 00:00:00
abstract::Three of five children who were born to consanguineous parents developed Guillain-Barré syndrome before they were 3 years old. The syndrome is rare in early childhood and we suggest that there may be a genetic element in the pathogenesis. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.66.9.1078
更新日期:1991-09-01 00:00:00
abstract:AIMS:To examine the disease burden and epidemiology of community acquired rotavirus gastroenteritis in Austrian children treated in a paediatric practice. METHODS:A prospective, population based, multicentre study in four paediatric practices and two children's hospitals (Innsbruck and Leoben). Children = 48 months ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/adc.84.5.393
更新日期:2001-05-01 00:00:00
abstract::Whole body protein synthesis and catabolism were measured using the [ring-2H5]phenylalanine and [1-13C]leucine primed constant infusion technique in 32 paediatric patients with cancer at different stages of treatment. Rates of synthesis (S) and catabolism (C) derived from the [ring-2H5]phenylalanine and [1-13C]leucine...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.75.4.273
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVE:There is a body of published research on the effectiveness of home visiting for the prevention of child maltreatment, but little in the peer reviewed literature on cost-effectiveness or value to society. The authors sought to determine the cost-effectiveness of alternative home visiting programmes to inform p...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/archdischild-2011-300795
更新日期:2012-09-01 00:00:00
abstract::We report a child with Down's syndrome in whom metrorrhagia and precocious puberty revealed primary autoimmune hypothyroidism. The patient had a decreased growth velocity, exaggerated weight gain, bone age delay, and bilaterally enlarged multicystic ovaries. Delays in the diagnosis and treatment of hypothyroidism can ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.88.4.330
更新日期:2003-04-01 00:00:00
abstract::The relation between intraventricular haemorrhage (IVH) and hyaline membrane disease (HMD) was studied in singletons that came to necropsy at Hammersmith Hospital over the years 1966-73. The incidence of IVH in singleton live births was 3-22/1000 and of HMD 4-44/1000. Although the high figures were partily due to the ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.10.755
更新日期:1976-10-01 00:00:00
abstract::349 Maasai children younger than 6 years old were randomised by alternate household to drink water either left in plastic bottles exposed to sunlight on the roof of the house or kept indoors (control). The trial was run in Maasai by Maasai community elders. Children drinking solar disinfected water had a significantly...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.81.4.337
更新日期:1999-10-01 00:00:00
abstract::Two hundred children with glass injuries were investigated; 48 were injured in falls through architectural glass and 87 by broken bottles. Nine children had serious lacerations--7 of which were sustained at home. Radiographs were important in diagnosing retained fragments but prophylactic antibiotics were unnecessary....
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.59.7.672
更新日期:1984-07-01 00:00:00
abstract::Concentrations of chorionic somatomammotrophin (hCS) in maternal plasma at the time of delivery and in placental extracts were determined by radioimmunoassay and related to neonatal growth in 111 normal pregnancies. Mean maternal plasma hCS concentration was lower in association with small-for-dates infants, defined b...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.2.120
更新日期:1976-02-01 00:00:00
abstract::Metabolites of vitamin D were measured in plasma from 83 patients with idiopathic infantile hypercalcaemia syndrome who were mentally handicapped but had normal calcium values at the time of the study. No significant difference was detected in the mean plasma concentrations of 25-hydroxyvitamin D2, 1,25-dihydroxyvitam...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.60.12.1140
更新日期:1985-12-01 00:00:00
abstract::Fine needle aspiration biopsy (FNAB) offers a simple outpatient technique for specimen collection in child tuberculosis suspects with peripheral lymphadenopathy. To perform FNAB with mycobacterial culture on an outpatient basis requires use of a sterile transport medium to facilitate bedside inoculation, maintain orga...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2009.164038
更新日期:2010-01-01 00:00:00
abstract::The long term results of treatment of inhalation of foreign bodies in a district children's hospital and in a tertiary referral centre were reviewed by clinical assessment, chest radiography, and standard four view 81mKr ventilation/99mTc macroaggregated albumin perfusion imaging (V/Q lung scan). The overall incidence...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.65.6.619
更新日期:1990-06-01 00:00:00
abstract:AIM:To document the impact that rapid increases in HIV infection in hospitalised children at Chris Hani Baragwanath Hospital has had on in-hospital mortality. METHODS:Hospital discharge summaries from January 1992 to the end of 1996 were reviewed. RESULTS:There were 20 733 admissions in the five year period; 7985 (39...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.83.3.227
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To examine information needs and preferences of parents regarding food allergy. DESIGN:Qualitative study including in-depth semi-structured interviews and focus group discussions. Data were audio-recorded, transcribed verbatim and analysed using the constant comparative method, aided by participant checking ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/adc.2006.114975
更新日期:2007-09-01 00:00:00
abstract::Moderate and severe malnutrition are endemic in much of the developing world and in association with pockets of deprivation in the developed world. The cost in terms of individual and social development is high. The principles of effective management are clearly documented. A low cost, community based treatment progra...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.71.4.297
更新日期:1994-10-01 00:00:00
abstract::Cystic fibrosis is a disease that still causes a reduced life expectancy. The treatment burden remains high for affected individuals with often a combination of multiple oral and inhaled medications, as well as physiotherapy, required on a daily basis. In this article, we look at an overview of the pathogenesis, how t...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/archdischild-2013-304400
更新日期:2014-11-01 00:00:00
abstract:AIM:To evaluate the risk factors for breakthrough varicella in a follow up study of a cohort of 181 healthy children immunised when aged 9-24 months with a reformulated Oka strain varicella vaccine (SmithKline Beecham Biologicals/Oka). DESIGN:The children were randomised in a double blind manner into one of four group...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.79.6.478
更新日期:1998-12-01 00:00:00
abstract::Plasma testosterone was estimated by radioimmunoassay in 60 children with disorders of sexual development before and after stimulation with human chorionic gonadotrophin (HCG). In 21 children the testosterone levels after 3 and 5 daily injections of 1000 units HCG were compared and good correlation was found between t...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.51.8.596
更新日期:1976-08-01 00:00:00
abstract::Of the 265 children aged between 6 and 18 months admitted to hospital in a 26-month period each with his first febrile convulsion, there were 64 who satisfied our criteria for a simple febrile convulsion. Of these, 43 (random) were entered into a double-blind trial of continuous sodium valproate versus phenobarbitone,...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章
doi:10.1136/adc.55.3.171
更新日期:1980-03-01 00:00:00
abstract::This study was carried out on the way in which children's beds were used by the specialty of paediatrics in a district general hospital. Five differing ways were found of interpreting the present Department of Health guidelines on health services information (Körner recommendations). These gave bed occupancy figures v...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.66.4.504
更新日期:1991-04-01 00:00:00
abstract:OBJECTIVE:To study the effect of body composition on average daily metabolic rate (ADMR) and basal metabolic rate (BMR) in adolescence, and to examine current BMR prediction equations. STUDY:Dutch adolescents were pooled with previously reported American and British subjects (n = 90 overall). BMR and ADMR were analyse...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.85.1.73
更新日期:2001-07-01 00:00:00