Abstract:
:Phenolic composition and antioxidant activities of the aqueous extract of Arisaema cum Bile, which is widely used as a folk medicine in Korea, were determined. Phenolic composition profile revealed that the aqueous extract is rich in sinapic acid (13.14 mg/100 g extract), catechin (9.88 mg/100 g extract), neohesperidin (7.38 mg/100 g extract), and chlorogenic acid (3.64 mg/100 g extract). The aqueous extract effectively scavenged toward 2,2-diphenyl-1-picrylhydrazyl (90.63%), hydrogen peroxide (98.13%), and hydroxyl radical (59.62%) at 2.0 mg/mL, and also showed high reducing power. In cytotoxic evaluation, the aqueous extract exhibited no significant cytotoxicity in human fibroblast, and it also exhibited appreciable suppression of intracellular reactive oxygen species and inhibition of lipid peroxidation. In addition, the aqueous extract upregulated the level of glutathione in a dose-dependent manner. Taken together, the aqueous extract of Arisaema cum Bile could be considered as a potential natural source that may be useful for curing diseases arising from oxidative deterioration.
journal_name
Immunopharmacol Immunotoxicoljournal_title
Immunopharmacology and immunotoxicologyauthors
Ahn CB,Shin TS,Seo HK,Je JYdoi
10.3109/08923973.2011.649289subject
Has Abstractpub_date
2012-08-01 00:00:00pages
661-6issue
4eissn
0892-3973issn
1532-2513journal_volume
34pub_type
杂志文章abstract:CONTEXT:Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by autoreactive antibodies. Recent findings revealed the importance of innate immune responses, especially Toll-like receptors (TLRs) in the pathogenesis of SLE. OBJECTIVE:In this study, the level of TLR9 expression on peripheral...
journal_title:Immunopharmacology and immunotoxicology
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journal_title:Immunopharmacology and immunotoxicology
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pub_type: 临床试验,杂志文章
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journal_title:Immunopharmacology and immunotoxicology
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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