Abstract:
:The immunopathogenesis of systemic lupus erythematosus has been thoroughly investigated recently, and genome-wide association studies have identified genes statistically associated with lupus. However, the progression to overt disease is dependent on the activation of environmental factors ('triggers'), among which oestrogen stimulation is prominent. Here we report the case of a mother with long-standing SLE entering into long term drug-free remission following intensive, menopause-inducing chemoradiotherapy for cancer, and the opposite case of her daughter, who developed SLE following the initiation of her menstrual cycle.
journal_name
Lupusjournal_title
Lupusauthors
Catania G,Rossi E,Marmont Adoi
10.1177/0961203311433138subject
Has Abstractpub_date
2012-05-01 00:00:00pages
672-4issue
6eissn
0961-2033issn
1477-0962pii
0961203311433138journal_volume
21pub_type
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