当前位置： SCI文献检索 > JOURNAL OF CLINICAL IMMUNOLOGY期刊下所有文献 > Lysophosphatidylethanolamine is the antigen to which apparent antibody to phosphatidylethanolamine binds.

Lysophosphatidylethanolamine is the antigen to which apparent antibody to phosphatidylethanolamine binds.

Abstract：

:Because binding of antiphospholipid antibody (aPL) to phosphatidylethanolamine (PE) is central to the definition of the antigenic epitope targeted by aPLs, we examined the binding of aPL-positive SLE sera to PE under various conditions. No serum bound to PE uncontaminated with lysophosphatidylethanolamine (1PE), but many aPL-positive sera bound to 1PE-contaminated PE and to 1PE coated onto an ELISA plate. Absorption studies indicated partial cross-reactivity between PE containing 1PE and cardiolipin. We conclude that clinical aPLs do not bind to PE. Prior reports to the contrary most likely represent binding of aPL to PE's degradation product, 1PE.

journal_name

J Clin Immunol

journal_title

Journal of clinical immunology

authors

Qamar T,Gharavi AE,Levy RA,Lockshin MD

doi

10.1007/BF00918652

subject

Has Abstract

pub_date

1990-07-01 00:00:00

pages

200-3

issue

4

eissn

0271-9142

issn

1573-2592

journal_volume

10

pub_type

杂志文章

相关文献

JOURNAL OF CLINICAL IMMUNOLOGY文献大全
  • Effect of lidocaine on neutrophil chemotaxis in newborn infants.

    abstract：:Anesthetic drugs can influence the immune system, particularly granulocyte function. The goal of the present study was to evaluate if lidocaine used for epidural anesthesia during cesarean section can influence neonatal neutrophil chemotaxis. We measured chemotaxis and plasma cord lidocaine and cortisol levels in (A) ...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1023/a:1020583022614

    authors： Gasparoni A,De Amici D,Ciardelli L,Autelli M,Regazzi-Bonora M,Bartoli A,Chirico G,Rondini G

    更新日期：1998-05-01 00:00:00

  • NK 1.1+ T cell: a two-faced lymphocyte in immune modulation of the IL-4/IFN-gamma paradigm.

    abstract：:T lymphocytes expressing NK1.1 marker (NK1.1+) have been suggested as being important in peripheral immune modulation. Alteration of the balance between Th1 proinflammatory and Th2 anti-inflammatory cytokine-producing cells can ameliorate immune-mediated disorders. The aim of the study was to determine the role of NK1...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1023/a:1019974005134

    authors： Trop S,Ilan Y

    更新日期：2002-09-01 00:00:00

  • Neurological Involvement in Childhood Evans Syndrome.

    abstract：PURPOSE:Immune thrombocytopenic purpura (ITP) and autoimmune hemolytic anemia (AIHA) are associated in the definition of Evans syndrome (ES). The occurrence of neurological involvement in this population is poorly described and suggests an underlying primary immunodeficiency (PID). We aimed to describe the clinical man...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-019-0594-3

    authors： Pincez T,Neven B,Le Pointe HD,Varlet P,Fernandes H,Gareton A,Leverger G,Leblanc T,Chambost H,Michel G,Pasquet M,Millot F,Hermine O,Mathian A,Hully M,Zephir H,Hamidou M,Durand JM,Perel Y,Landman-Parker J,Rieux-Lauc

    更新日期：2019-02-01 00:00:00

  • Altered miRNAs expression profiles and modulation of immune response genes and proteins during neonatal sepsis.

    abstract：PURPOSE:The dysregulated expression of miRNAs in the immune system may be critical for immune responses to pathogens and evolve into the inflammation seen in sepsis. The aim of this study is to explore the important role of miRNAs in the regulation of the immune response during neonatal sepsis. METHODS:Using a microar...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-014-0004-9

    authors： Chen J,Jiang S,Cao Y,Yang Y

    更新日期：2014-04-01 00:00:00

  • The presence of anti-carcinoembryonic antigen (CEA) antibodies in the sera of patients with gastrointestinal malignancies.

    abstract：:Using an enzyme-linked immunoassay we tested the sera of 71 patients with digestive system cancer, 35 patients with various nonmalignant disorders, and 28 normal individuals for anti-CEA activity. Antibodies were found in the sera of 51% of the patients. Most of the patients positive for the antibodies (70%) had no ev...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/BF01540984

    authors： Konstadoulakis MM,Syrigos KN,Albanopoulos C,Mayers G,Golematis B

    更新日期：1994-09-01 00:00:00

  • N-acetylcysteine administration is associated with reduced activation of NF-kB and preserves lung dendritic cells function in a zymosan-induced generalized inflammation model.

    abstract：PURPOSE:In severe sepsis, functional impairment and decreased numbers of dendritic cells (DCs) are essential reasons for immune function paralysis, secondary organ infection, and organ failure. We investigated the effects of N-acetylcysteine (NAC) administration on protecting lung DCs function in a zymosan-induced gene...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-012-9852-3

    authors： Wang HW,Yang W,Lu JY,Li F,Sun JZ,Zhang W,Guo NN,Gao L,Kang JR

    更新日期：2013-04-01 00:00:00

  • Frequent anti-V-region immune response to mouse B72.3 monoclonal antibody.

    abstract：:The immune response of 56 colorectal cancer patients to a single infusion of 1 mg of radiolabeled (111In) mouse B72.3-GYK-DTPA immunoconjugate was examined using a double-antigen radiometric assay system. The incidence of antibody response was 48% to polyclonal mouse IgG, 71% to mouse B72.3, and 62% to chimeric B72.3....

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/BF00918141

    authors： Khazaeli MB,Saleh MN,Liu T,Kaladas PM,Gilman SC,LoBuglio AF

    更新日期：1992-03-01 00:00:00

  • Disorders of apoptosis: mechanisms for autoimmunity in primary immunodeficiency diseases.

    abstract：:A number of primary immunodeficiency diseases represent a paradox of immunodeficiency and autoimmunity. In this minireview, we present basic concepts of apoptosis and disorder of apoptosis as one of the mechanisms to explain such a paradox between immunodeficiency and autoimmunity, which is exemplified by autoimmune l...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章,评审

    doi：10.1007/s10875-007-9161-4

    authors： Oliveira JB,Gupta S

    更新日期：2008-05-01 00:00:00

  • Phagocyte chemotaxis in the perinatal period.

    abstract：:Cross-sectional and limited sequential studies of neutrophil and monocyte chemotaxis were done using cells isolated from cord blood and peripheral blood of 2- to 6-day-old neonates and infants at 4 and 6 months of age. These studies show that cord blood phagocyte chemotaxis is comparable to adult values, whereas phago...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/BF00915228

    authors： Raghunathan R,Miller ME,Everett S,Leake RD

    更新日期：1982-07-01 00:00:00

  • Disparity in FcεRI-induced degranulation of primary human lung and skin mast cells exposed to adenosine.

    abstract：:Inhaled and intravenously administered adenosine induces mast cell-mediated (histamine-dependent) bronchospasm in asthmatics without causing urticaria. A differential response to adenosine by human lung and skin mast cells is shown: low concentrations potentiate FcεRI-induced degranulation of human lung mast cells but...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-011-9517-7

    authors： Gomez G,Zhao W,Schwartz LB

    更新日期：2011-06-01 00:00:00

  • Immunological functions and phenotypes of peripheral blood lymphocytes from human T-cell leukemia virus-I carriers.

    abstract：:We studied immunological functions of peripheral blood lymphocytes (PBL) from human T-cell leukemia virus type I (HTLV-I)-seropositive healthy carriers in vitro. Proliferative responses of PBL to T-cell and B-cell mitogens such as concanavalin A (Con A), pokeweed mitogen (PWM), and Staphylococcus aureus Cowan I (SAC) ...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/BF00918017

    authors： Tanaka Y,Oda S,Nagata K,Mori N,Sakamoto H,Eto S,Yamashita U

    更新日期：1989-11-01 00:00:00

  • Current state of the hybridoma technology.

    abstract：:The first description of the hybridoma technology in 1975 seemed to hold enormous promise for the treatment of a variety of human disease. The ability to produce monoclonal antibodies led to the availability of large amounts of homogeneous and predictable preparations of antibody. The potential to renew indefinitely a...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章,评审

    doi：10.1007/BF00918686

    authors： Pirofski L,Casadevall A,Rodriguez L,Zuckier LS,Scharff MD

    更新日期：1990-11-01 00:00:00

  • Endogenously activated interleukin-4 differentiates disease progressors and non-progressors in tuberculosis susceptible families: a 2-year biomarkers follow-up study.

    abstract：OBJECTIVE:Dynamic cytokine profiles from endogenously activated T cells in transit from lymph node to the infected sites via the blood compartment after recent exposure to Mycobacterium tuberculosis may differentiate disease progressors from non-disease progressors in a BCG-vaccinated population. METHODS:Household con...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-011-9566-y

    authors： Hussain R,Talat N,Ansari A,Shahid F,Hasan Z,Dawood G

    更新日期：2011-10-01 00:00:00

  • Reduced type 1 and type 2 cytokines in antiviral memory T helper function among women coinfected with HIV and HCV.

    abstract：:Bias in cytokine responses has been proposed as a contributing mechanism to pathogenesis in persistent HIV or hepatitis C virus (HCV) infections. We investigated whether coinfection with HCV modifies the profile of antigen-specific cytokine secretion in women persistently infected with HIV compared to women with singl...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-005-2819-x

    authors： Villacres MC,Literat O,Degiacomo M,Du W,La Rosa C,Diamond DJ,Kovacs A

    更新日期：2005-03-01 00:00:00

  • Nocardiosis Associated with Primary Immunodeficiencies (Nocar-DIP): an International Retrospective Study and Literature Review.

    abstract：PURPOSE:Nocardiosis is a life-threatening infectious disease. We aimed at describing nocardiosis in patients with primary immunodeficiency diseases (PID). METHODS:This international retrospective cohort included patients with PID and nocardiosis diagnosed and/or published from Jan 1, 2000, to Dec 31, 2016. To identify...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-020-00866-8

    authors： Lafont E,Marciano BE,Mahlaoui N,Neven B,Bustamante J,Rodriguez-Nava V,Rawat A,Unzaga MJ,Fischer A,Blanche S,Lortholary O,Holland SM,Lebeaux D

    更新日期：2020-11-01 00:00:00

  • Complement Activation in 22q11.2 Deletion Syndrome.

    abstract：:The 22q11.2 deletion syndrome (22q11.2 del), also known as DiGeorge syndrome, is a genetic disorder with an estimated incidence of 1:3000 to 1:6000 births. These patients may suffer from affection of many organ systems with cardiac malformations, immunodeficiency, hypoparathyroidism, autoimmunity, palate anomalies, an...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-020-00766-x

    authors： Grinde D,Øverland T,Lima K,Schjalm C,Mollnes TE,Abrahamsen TG

    更新日期：2020-04-01 00:00:00

  • The Use of Salmonella Typhim Vaccine to Diagnose Antibody Deficiency.

    abstract：PURPOSE:The specific antibody response to the unconjugated 23-valent pneumococcal polysaccharide vaccine is one of the most common tests used to assess for possible humoral immunodeficiency. The results can be difficult to interpret because most people have been immunized with one or more of the pneumococcal vaccines a...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-017-0406-6

    authors： Bausch-Jurken MT,Verbsky JW,Gonzaga KA,Elms NP,Hintermeyer MK,Gauld SB,Routes JM

    更新日期：2017-07-01 00:00:00

  • Infectious and immunologic phenotype of MECP2 duplication syndrome.

    abstract：:MECP2 (methyl CpG binding protein 2) duplication causes syndromic intellectual disability. Patients often suffer from life-threatening infections, suggesting an additional immunodeficiency. We describe for the first time the detailed infectious and immunological phenotype of MECP2 duplication syndrome. 17/27 analyzed ...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-015-0129-5

    authors： Bauer M,Kölsch U,Krüger R,Unterwalder N,Hameister K,Kaiser FM,Vignoli A,Rossi R,Botella MP,Budisteanu M,Rosello M,Orellana C,Tejada MI,Papuc SM,Patat O,Julia S,Touraine R,Gomes T,Wenner K,Xu X,Afenjar A,Toutain

    更新日期：2015-02-01 00:00:00

  • Augmentation of natural and antibody-dependent cell-mediated cytotoxicity by pure human leukocyte interferon.

    abstract：:Augmentation of the cytolytic activity of human natural killer cells and of antibody-dependent cell-mediated cytotoxicity has been attributed to human interferons. With the purification to homogeneity of human leukocyte interferon, it became possible to test directly whether pure interferon could increase the activity...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/BF00922756

    authors： Herberman RB,Ortaldo JR,Rubinstein M,Pestka S

    更新日期：1981-07-01 00:00:00

  • Matrix metalloproteinase-9 and autoimmune diseases.

    abstract：:Matrix metalloproteinases (also named matrixin or MMPs) are a major group of enzymes that regulate cell-matrix composition by using zinc for their proteolytic activities. They are essential for various normal biological processes such as embryonic development, morphogenesis, reproduction tissue resorption, and remodel...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章,评审

    doi：10.1007/s10875-006-9022-6

    authors： Ram M,Sherer Y,Shoenfeld Y

    更新日期：2006-07-01 00:00:00

  • Quantification of immunoglobulin free light chains in cerebrospinal fluid by nephelometry.

    abstract：:Oligoclonal free light chains (FLC) banding has been described in multiple sclerosis (MS) and should be correlated with disease activity. However, discrepancies between studies have been reported because of differences in methods. A new quantitative, rapid, and automated method using nephelometry is now available. Our...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-005-5371-9

    authors： Desplat-Jégo S,Feuillet L,Pelletier J,Bernard D,Chérif AA,Boucraut J

    更新日期：2005-07-01 00:00:00

  • Anti-ribosomal ribonucleoprotein autoantibodies in systemic lupus erythematosus.

    abstract：:Sera from systemic lupus erythematosus (SLE) patients giving a fluorescent ribosomal pattern on tissue and cell preparations also showed precipitating autoantibodies against purified rat liver ribosomes. Ribosomal antigen is also present in rabbit thymus cellular extract (RTE), since the same sera gave precipitin line...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/BF00915287

    authors： Meroni PL,de Bartolo G,Barcellini W,Riboldi PS,Basile R,Betterle C,Zanussi C

    更新日期：1984-01-01 00:00:00

  • Health-Related Quality of Life and Health Resource Utilization in Patients with Primary Immunodeficiency Disease Prior to and Following 12 Months of Immunoglobulin G Treatment.

    abstract：PURPOSE:Health-related quality of life (HRQOL) has not been examined in patients with predominant antibody deficiency both pre- and post-immunoglobulin G (IgG) treatment initiation. HRQOL and health resource utilization (HRU) were assessed in newly diagnosed patients with primary immunodeficiency disease (PIDD) pre- an...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-016-0279-0

    authors： Routes J,Costa-Carvalho BT,Grimbacher B,Paris K,Ochs HD,Filipovich A,Hintermeyer M,de Melo KM,Workman S,Ito D,Ye X,Bonnet P,Li-McLeod J

    更新日期：2016-07-01 00:00:00

  • DNA methylation and the expression of IL-4 and IFN-gamma promoter genes in patients with bronchial asthma.

    abstract：:Although CpG methylation is thought to be a negative regulator of gene transcription, its relationship with cytokine expression remains unclear. Interleukin (IL)-4 and interferon (IFN)-gamma are major cytokines that affect the differentiation of naïve CD4+ T lymphocytes into the Th1 and Th2 lineage. We used bisulfite ...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-007-9148-1

    authors： Kwon NH,Kim JS,Lee JY,Oh MJ,Choi DC

    更新日期：2008-03-01 00:00:00

  • Distinctive patterns of release of neuroendocrine peptides after nasal challenge of allergic subjects with ryegrass antigen.

    abstract：:The concentrations of the neuropeptides substance P, somatostatin, and calcitonin gene-related peptide in human nasal secretions were quantified by radioimmunoassays, concurrently with that of histamine, in the course of nasal challenge of allergic and control subjects with ryegrass antigen to examine contributions of...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/BF00917898

    authors： Walker KB,Serwonska MH,Valone FH,Harkonen WS,Frick OL,Scriven KH,Ratnoff WD,Browning JG,Payan DG,Goetzl EJ

    更新日期：1988-03-01 00:00:00

  • Subset markers of CD8(+) cells and their relation to enhanced cytotoxic T-cell activity during human immunodeficiency virus infection.

    abstract：:Using fresh whole blood or isolated lymphocytes, the activity of in vivo generated cytotoxic T-lymphocytes (CTL) was measured as the OKT3-specific lysis of HL-60 targets, in a cross-sectional study of 53 HIV (+) patients. CTL activity in the entire HIV(+) group was two to three times higher than in HIV(-) controls, wi...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/BF00918800

    authors： Vanham G,Kestens L,Penne G,Goilav C,Gigase P,Colebunders R,Vandenbruaene M,Goeman J,van der Groen G,Ceuppens JL

    更新日期：1991-11-01 00:00:00

  • Modulation of the proteome of peripheral blood mononuclear cells from HIV-1-infected patients by drugs of abuse.

    abstract：INTRODUCTION:We used proteomic analyses to assess how drug abuse modulates immunologic responses to infections with the human immunodeficiency virus type 1 (HIV-1). METHODS:Two-dimensional difference gel electrophoresis was utilized to determine changes in the proteome of peripheral blood mononuclear cells (PBMC) isol...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-009-9309-5

    authors： Reynolds JL,Mahajan SD,Aalinkeel R,Nair B,Sykes DE,Agosto-Mujica A,Hsiao CB,Schwartz SA

    更新日期：2009-09-01 00:00:00

  • Clinical and molecular characteristics of 35 Chinese children with Wiskott-Aldrich syndrome.

    abstract：BACKGROUND:Wiskott-Aldrich syndrome (WAS) is a rare primary immunodeficiency disease, with an incidence of 4/1,000,000 live male births. In China, an estimated number of 35 babies with WAS are born each year, but likely many remain undiagnosed. OBJECTIVES:The objectives of study were to review the clinical and molecul...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-009-9285-9

    authors： Lee PP,Chen TX,Jiang LP,Chen J,Chan KW,Lee TL,Ho MH,Nong SH,Yang Y,Fang YJ,Li Q,Wang XC,Yang XQ,Lau YL

    更新日期：2009-07-01 00:00:00

  • A Unique Presentation of Infantile-Onset Colitis and Eosinophilic Disease without Recurrent Infections Resulting from a Novel Homozygous CARMIL2 Variant.

    abstract：PURPOSE:This study aimed to characterize the clinical phenotype, genetic basis, and consequent immunological phenotype of a boy with severe infantile-onset colitis and eosinophilic gastrointestinal disease, and no evidence of recurrent or severe infections. METHODS:Trio whole-exome sequencing (WES) was utilized for pa...

    journal_title：Journal of clinical immunology

    pub_type： 杂志文章

    doi：10.1007/s10875-019-00631-6

    authors： Kurolap A,Eshach Adiv O,Konnikova L,Werner L,Gonzaga-Jauregui C,Steinberg M,Mitsialis V,Mory A,Nunberg MY,Wall S,Shaoul R,Overton JD,Regeneron Genetics Center.,Shuldiner AR,Zohar Y,Paperna T,Snapper SB,Shouval DS,Bari

    更新日期：2019-05-01 00:00:00

  • Cervical concentrations of interleukin-10 and interleukin-12 do not correlate with plasma levels.

    abstract：:Human papillomavirus (HPV) infects the transformation zone of the cervix and is the primary cause of cervical cancer. The infection is localized to the cervix and mucosal immunity is likely to be an important determinant for viral clearance. Previous studies of immunity to HPV have measured immune markers in the blood...

    journal_title：Journal of clinical immunology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1023/a:1014252402630

    authors： Castle PE,Hildesheim A,Bowman FP,Strickler HD,Walker JL,Pustilnik T,Edwards RP,Crowley-Nowick PA

    更新日期：2002-01-01 00:00:00