Disorders of apoptosis: mechanisms for autoimmunity in primary immunodeficiency diseases.

Abstract:

:A number of primary immunodeficiency diseases represent a paradox of immunodeficiency and autoimmunity. In this minireview, we present basic concepts of apoptosis and disorder of apoptosis as one of the mechanisms to explain such a paradox between immunodeficiency and autoimmunity, which is exemplified by autoimmune lymphoproliferative syndrome (ALPS).

journal_name

J Clin Immunol

authors

Oliveira JB,Gupta S

doi

10.1007/s10875-007-9161-4

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

S20-8

eissn

0271-9142

issn

1573-2592

journal_volume

28 Suppl 1

pub_type

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