Mycophenolate mofetil as a maintenance therapy for lupus-related diffuse alveolar hemorrhage: a case report.

abstract：:Several studies have investigated the potential of various autoantibody tests in the diagnosis of systemic lupus erythematosus (SLE). Many lupus patients initially present with glomerulonephritis. In that clinical situation the main differential diagnosis are other forms of glomerulonephritis. In this study the diagno...

journal_title：Lupus

authors： Heidenreich U,Mayer G,Herold M,Klotz W,Stempfl Al-Jazrawi K,Lhotta K

更新日期：2009-12-01 00:00:00

abstract：:The object of this study was to compare patients with familial versus sporadic systemic lupus erythematosus (SLE) with respect to clinical, laboratory variables and outcome. The familial SLE group comprised 12 patients while the comparative group comprised 24 patients selected by systemic sampling from our pediatric r...

journal_title：Lupus

authors： Al-Mayouf SM,Al Sonbul A

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Ferritin is an iron storage protein considered also as an acute phase reactant with high levels in various inflammatory conditions. Recently, a plausible role for ferritin in the pathogenesis of immune-mediated and especially autoimmune diseases has been suggested. However, the link between ferritin and the ...

journal_title：Lupus

authors： Agmon-Levin N,Rosário C,Katz BS,Zandman-Goddard G,Meroni P,Cervera R,Stojanovich L,Blank M,Pierangeli S,Praprotnik S,Meis Ed,Seguro LP,Ruffatti A,Pengo V,Tincani A,Doria A,Shoenfeld Y

更新日期：2013-11-01 00:00:00

abstract：:Lupus nephritis (LN) is usually associated with widespread effacement of the podocytes' foot processes leading to proteinuria. Induction of urokinase receptor (uPAR) signaling in podocytes leads to foot process effacement and urinary protein loss via promoting podocytes' motility and kidney permeability in the glomeru...

journal_title：Lupus

authors： Cheng CC,Lee YF,Lan JL,Wu MJ,Hsieh TY,Lin NN,Wang JM,Chiu YT

更新日期：2013-05-01 00:00:00

abstract：:The aim of this study was to determine the frequency of anti-prolactin autoantibodies and the relationship among anti-prolactin autoantibodies, serum prolactin (PRL) levels and lupus activity in paediatric patients with systemic lupus erythematosus (SLE) using a transversal study. One-hundred and three consecutive pae...

journal_title：Lupus

authors： Blanco-Favela F,Quintal MaG,Chavez-Rueda AK,Leaños-Miranda A,Berron-Peres R,Baca-Ruiz V,Lavalle-Montalvo C

更新日期：2001-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE), a disorder of the immune system, is potentially curable by allogeneic bone marrow transplantation (alloBMT). Until recently, alloBMT was limited by donor availability and toxicity. Reduced intensity conditioning (RIC) combined with post-transplantation cyclophosphamide (PTCy) has im...

journal_title：Lupus

authors： Gladstone DE,Petri M,Bolaños-Meade J,Dezern AE,Jones RJ,Fine D,Brodsky RA

更新日期：2017-06-01 00:00:00

abstract：:Cyclophosphamide (CYC) is used in severe neuropsychiatric systemic lupus erythematosus (NPSLE), but long-term data regarding its efficacy and safety are lacking. We identified NPSLE cases who received CYC from two centres during the period 1999-2013 and had regular follow-up. General and neuropsychiatric outcome at la...

journal_title：Lupus

authors： Fanouriakis A,Pamfil C,Sidiropoulos P,Damian L,Flestea A,Gusetu G,Rednic S,Bertsias G,Boumpas DT

更新日期：2016-05-01 00:00:00

abstract：:Objective The lupus impact tracker (LIT) is a 10-item patient reported outcome tool to measure the impact of systemic lupus erythematosus or its treatment on patients' daily lives. Herein, we describe the responsiveness of the LIT and LupusQoL to changes in disease activity, using the systemic lupus erythematosus resp...

journal_title：Lupus

authors： Devilliers H,Bonithon-Kopp C,Jolly M

更新日期：2017-04-01 00:00:00

abstract：:The objective of this study was to determine the vitamin D status and its relationship with disease and therapy features and with bone mineral density in women with systemic lupus erythematosus. Non-pregnant systemic lupus erythematosus women with dual-energy X-ray absorptiometry and vitamin D measurements performed b...

journal_title：Lupus

authors： Toloza SM,Cole DE,Gladman DD,Ibañez D,Urowitz MB

更新日期：2010-01-01 00:00:00

abstract：:An assessment of prevalence for systemic lupus erythematosus (SLE) has been attempted for the population of far north Queensland in Australia. This huge area has a majority Caucasian population living in a tropical environment. Roughly 10% of the population comprises people of Australian Aboriginal or Torres Strait Is...

journal_title：Lupus

authors： Bossingham D

更新日期：2003-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a severe chronic inflammatory autoimmune connective tissue disease. Despite major efforts, SLE remains a poorly understood disease with unpredictable course, unknown etiology and complex pathogenesis. Apoptosis combined with deficiency in clearing apoptotic cells is an important e...

journal_title：Lupus

authors： Delfani P,Sturfelt G,Gullstrand B,Carlsson A,Kassandra M,Borrebaeck CA,Bengtsson AA,Wingren C

更新日期：2017-04-01 00:00:00

abstract：:Pericardial effusions causing pericardial tamponade are rare in patients with systemic lupus erythematosus (SLE). The goal of this study is to describe in detail the clinical and laboratory characteristics of a group of patients with pericardial effusions and pericardial tamponade secondary to SLE. We retrospectively ...

journal_title：Lupus

authors： Rosenbaum E,Krebs E,Cohen M,Tiliakos A,Derk CT

更新日期：2009-06-01 00:00:00

abstract：:Glycans (sugars or carbohydrates) are predominant surface components of cells such as erythrocytes, immune cells and microorganisms. As such, they give rise to high levels of anti-glycan antibodies of all classes. Antibodies to certain defined mono, di and oligosaccharides that are common in bacterial, fungal and para...

journal_title：Lupus

authors： Dotan N,Altstock RT,Schwarz M,Dukler A

更新日期：2006-01-01 00:00:00

abstract：:Due to recent acquisitions, diagnostic criteria for the antiphospholipid/cofactors syndrome need to be improved. In the absence of a "common biological denominator", the best approach should be based on a scoring system mixing clinical and immunological items. APS might be composed of different biological subsets char...

journal_title：Lupus

authors： Piette JC

更新日期：1996-10-01 00:00:00

abstract：:The purpose of this study was to evaluate the clinical characteristics of women with systemic lupus erythematosus (SLE) sent for a dual energy X-ray absorptiometry (DEXA) study, and to analyse the factors associated with a lower bone mineral density in these patients. Women with SLE who had a DEXA done between 1 Janua...

journal_title：Lupus

authors： Pineau CA,Urowitz MB,Fortin PJ,Ibanez D,Gladman DD

更新日期：2004-01-01 00:00:00

abstract：:We have previously shown that elevation of anticardiolipin antibodies (aCL) at the first prenatal visit is associated with increased fetal loss in normal pregnancy. The variation in aCL levels during normal pregnancy has not been established. To examine this question we measured IgG, IgM and IgA aCL levels five times ...

journal_title：Lupus

authors： Lynch AM,Rutledge JH,Stephens JK,Murphy JR,Marlar RA,Davila GH,Santos ME,Emlen W

更新日期：1995-10-01 00:00:00

abstract：INTRODUCTION:Anti-ganglioside antibodies (AGA) have been associated with several peripheral neuropathies, such as Miller-Fisher syndrome, Guillain-Barré syndrome and multifocal motor neuropathy. They have also been studied in patients with systemic lupus erythematosus (SLE), focusing on neuropsychiatric manifestations ...

journal_title：Lupus

authors： Labrador-Horrillo M,Martinez-Valle F,Gallardo E,Rojas-Garcia R,Ordi-Ros J,Vilardell M

更新日期：2012-05-01 00:00:00

abstract：:HIN200 is a human IFN-inducible gene and homologous to murine IFI202 gene, which was identified as a candidate gene for SLE susceptibility in lupus mouse model. We determined these gene expressions in leukocytes from 20 SLE patients and 10 healthy controls and in renal biopsies from 29 SLE patients and 15 kidney donor...

journal_title：Lupus

authors： Kimkong I,Avihingsanon Y,Hirankarn N

更新日期：2009-10-01 00:00:00

abstract：:Allergic disorders commonly occur in patients with systemic lupus erythematosus (SLE) and allergies to some drugs may occasionally be related to disease flares. We evaluated the prevalence of several types of allergy in 132 patients with SLE and their families and compared the SLE patients with a control group of 66 p...

journal_title：Lupus

authors： Sequeira JF,Cesic D,Keser G,Bukelica M,Karanagnostis S,Khamashta MA,Hughes GR

更新日期：1993-06-01 00:00:00

abstract：:Although the importance of the anticardiolipin test in diagnosis of antiphospholipid syndrome (APS) is widely accepted, there remains much misunderstanding about the strengths and weaknesses of this assay. Several disorders result in formation of low levels of the antibody, hence the anticardiolipin test is not specif...

journal_title：Lupus

authors： Harris EN,Pierangeli SS

更新日期：2002-01-01 00:00:00

abstract：:Our objective was to investigate whether quality of life in systemic lupus erythematosus (SLE) differs across ethnoracial groups and to identify factors that may explain race-related differences. Self-administered questionnaire data from 335 White, 40 Black, and 30 Asian women with SLE were obtained from a multi-cente...

journal_title：Lupus

authors： Devins GM,Edworthy SM

更新日期：2000-01-01 00:00:00

abstract：:The Systemic Lupus International Collaborating Clinics/American College of Rheumatology (ACR) Damage Index (SDI) is an accepted instrument to ascertain damage. It has been shown to vary among different SLE populations. The aim of this study was to assess SDI score, pattern and factors related to damage in Brazilian SL...

journal_title：Lupus

authors： Soares M,Reis L,Papi JA,Cardoso CR

更新日期：2003-01-01 00:00:00

abstract：:Objectives We analyzed the clinical follow-up results of 88 lupus nephritis patients to find prognostic factors for the development of chronic kidney disease in ethnically homogeneous Korean patients with biopsy-proven lupus nephritis. Methods Sociodemographic, clinical, laboratory, and treatment-related data at the t...

journal_title：Lupus

authors： Park DJ,Kang JH,Lee JW,Lee KE,Kim TJ,Park YW,Lee JS,Choi YD,Lee SS

更新日期：2017-10-01 00:00:00

abstract：:Tumour necrosis factor (TNFalpha) is a cytokine with a wide range of diverse and at times paradoxical effects. These include immunoregulatory, lymphoid organogenesis and pro-inflammatory effects. In recent years, TNFalpha has become a focus of interest more for its inflammatory effects in a number of chronic autoimmun...

journal_title：Lupus

authors： Mageed RA,Isenberg DA

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:The feed-forward loop of type I interferons (IFNs) production and subsequent immunopathology of systemic lupus erythematosus (SLE) has been hypothesised to be disrupted with inhibition of IFNα or type I IFN receptor subunit 1 (IFNAR). This systematic review and meta-analysis present the treatment efficacy and...

journal_title：Lupus

authors： Koh JWH,Ng CH,Tay SH

更新日期：2020-12-01 00:00:00

abstract：:Anti-phospholipid antibodies are common in patients in the Hopkins' Lupus Cohort: 47% have anti-cardiolipin, 32.5% anti-beta(2)-glycoprotein I and 26% lupus anticoagulant (by dRVVT confirmatory testing). Systemic lupus erythematosus patients with the lupus anticoagulant at baseline have a 50% chance of a deep venous t...

journal_title：Lupus

authors： Petri M

更新日期：2010-04-01 00:00:00

abstract：:The objective of this study was to determine the HLA class II associations of the anticardiolipin (aCL) and anti-beta2GPI (abeta2GPI) antibodies in a large series of European patients with systemic lupus erythematosus (SLE). A cohort of 577 European SLE patients was enrolled. aCL and abeta2GPI were measured by ELISA m...

journal_title：Lupus

authors： Galeazzi M,Sebastiani GD,Tincani A,Piette JC,Allegri F,Morozzi G,Bellisai F,Scorza R,Ferrara GB,Carcassi C,Font J,Passiu G,Smolen J,Papasteriades C,Houssiau F,Nebro AF,Ramon Garrido ED,Jedryka-Goral A,Marcolongo R

更新日期：2000-01-01 00:00:00

abstract：:The F(1) progeny of the (SWR × NZB) cross develop a lupus-like disease with high serum titers of autoantibodies, and increased frequency and severity of immune complex-mediated glomerulonephritis in females. In previous work, we found that an idiotypic peptide corresponding to aa62-73 (p62-73) of the heavy chain varia...

journal_title：Lupus

authors： Nyland JF,Stoll ML,Jiang F,Feng F,Gavalchin J

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:The heterogeneous spectrum of systemic lupus erythematosus (SLE) often presents with secondary complications such as cardiovascular disease (CVD), infections and neoplasms. Our study assessed whether the presence of SLE independently increases or reduces the disparities, accounting for the already higher risk...

journal_title：Lupus

authors： Falasinnu T,Chaichian Y,Li J,Chung S,Waitzfelder BE,Fortmann SP,Palaniappan L,Simard JF

更新日期：2019-12-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with a suggested genetic basis. The newly identified human programmed cell death 1 gene could be associated with SLE susceptibility. We aimed to investigate the association between programmed cell death 1 polymorphism (PD1.3G/A (rs11568821) and PD1...

journal_title：Lupus

authors： Abo El-Khair SM,Sameer W,Awadallah N,Shaalan D

更新日期：2019-10-01 00:00:00