Duration of red blood cell storage and outcomes in pediatric cardiac surgery: an association found for pump prime blood.

abstract：BACKGROUND:Early identification of predictors for a poor long-term outcome in patients who survive the initial phase of out-of-hospital cardiac arrest (OHCA) may facilitate future clinical research, the process of care and information provided to relatives. The aim of this study was to determine the association between...

journal_title：Critical care (London, England)

authors： Martinell L,Nielsen N,Herlitz J,Karlsson T,Horn J,Wise MP,Undén J,Rylander C

更新日期：2017-04-13 00:00:00

abstract：INTRODUCTION:The purpose of the present study was to critically review the existing body of evidence on ventilation modes for infants and children up to the age of 18 years. METHODS:The PubMed and EMBASE databases were searched using the search terms 'artificial respiration', 'instrumentation', 'device', 'devices', 'm...

journal_title：Critical care (London, England)

authors： Duyndam A,Ista E,Houmes RJ,van Driel B,Reiss I,Tibboel D

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Mechanically ventilated critically ill patients frequently develop ventilator-associated pneumonia (VAP), a life-threatening complication. Proposed preventive measures against VAP include, but are not restricted to, selective decontamination of the digestive tract (SDD), selective oropharyngeal decontamina...

journal_title：Critical care (London, England)

authors： Schultz MJ,Haas LE

更新日期：2011-01-01 00:00:00

abstract：:Institutionally based research ethics review is a form of peer review that has - for better or worse - become the norm throughout the world. The vast majority of research ethics review takes the form of protocol review alone, conducted in advance of the research. Although oversight and monitoring in clinical research ...

journal_title：Critical care (London, England)

authors： Lavery JV,Van Laethem ML,Slutsky AS

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Middle East respiratory syndrome coronavirus infection is associated with high mortality rates but limited clinical data have been reported. We describe the clinical features and outcomes of patients admitted to an intensive care unit (ICU) with Middle East respiratory syndrome coronavirus (MERS-CoV) infecti...

journal_title：Critical care (London, England)

authors： Almekhlafi GA,Albarrak MM,Mandourah Y,Hassan S,Alwan A,Abudayah A,Altayyar S,Mustafa M,Aldaghestani T,Alghamedi A,Talag A,Malik MK,Omrani AS,Sakr Y

更新日期：2016-05-07 00:00:00

abstract：BACKGROUND:The shock index (SI), defined as heart rate (HR) divided by systolic blood pressure (SBP), is reported to be a more sensitive marker of shock than traditional vital signs alone. In previous literature, use of the reverse shock index (rSI), taken as SBP divided by HR, is recommended instead of SI for hospital...

journal_title：Critical care (London, England)

authors： Kimura A,Tanaka N

更新日期：2018-04-11 00:00:00

abstract：:The impressive benefits related to the use of tight glucose control by intensive insulin therapy have not been reproduced until now in multicenter large-scale prospective randomized trials. Although the reasons for these failures are not entirely clear, we suggest the use of a stepwise approach - Safe, Effective Gluco...

journal_title：Critical care (London, England)

authors： Krinsley JS,Preiser JC

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Critical illness myopathy is an acquired skeletal muscle disorder with severe myosin loss and muscle weakness frequently seen in intensive care unit (ICU) patients. It is unknown if impaired excitation-contraction coupling contributes to the muscle weakness. METHODS:We used a unique ICU model where rats wer...

journal_title：Critical care (London, England)

authors： Llano-Diez M,Cheng AJ,Jonsson W,Ivarsson N,Westerblad H,Sun V,Cacciani N,Larsson L,Bruton J

更新日期：2016-08-10 00:00:00

abstract：:BACKGROUND: In recent years, rural hospitals have expanded their scope of specialized services, which has led to the development and staffing of rural intensive care units (ICUs). There is little information about the breadth, quality or outcomes of these services. This is particularly true for specialized ICU service...

journal_title：Critical care (London, England)

authors： Fieselmann JF,Bock MJ,Hendryx MS,Wakefield D,Helms CM,Bentler SE

更新日期：1999-01-01 00:00:00

abstract：:Recent studies challenge the utility of central venous pressure monitoring as a surrogate for cardiac preload. Starting with Starling's original studies on the regulation of cardiac output, this review traces the history of the experiments that elucidated the role of central venous pressure in circulatory physiology. ...

journal_title：Critical care (London, England)

authors： Berlin DA,Bakker J

更新日期：2015-02-16 00:00:00

abstract：INTRODUCTION:The FloTrac/Vigileo (Edwards Lifesciences, Irvine, CA, USA) allows pulse pressure-derived cardiac output measurement without external calibration. Software modifications were performed in order to eliminate initially observed deficits. The aim of this study was to assess changes in cardiac output determine...

journal_title：Critical care (London, England)

authors： Senn A,Button D,Zollinger A,Hofer CK

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Although activation of A3 adenosine receptors attenuates reperfusion lung injury and associated apoptosis, the signaling pathway that mediates this protection remains unclear. Adenosine agonists activate mitogen-activated protein kinases, and these kinases have been implicated in ischemia/reperfusion injur...

journal_title：Critical care (London, England)

authors： Matot I,Weiniger CF,Zeira E,Galun E,Joshi BV,Jacobson KA

更新日期：2006-01-01 00:00:00

abstract：:Great white sharks are responsible for about 10 cases of death annually worldwide, as compared with millions of deaths caused by sepsis. However, the basic principles of avoiding shark attacks and fighting sepsis seem to be similar: avoidance, attention, and speed, if necessary. The present review discusses the curren...

journal_title：Critical care (London, England)

authors： Westphal M,Kampmeier T

更新日期：2015-01-01 00:00:00

abstract：:Developments in recent years have placed powerful new tools of diagnosis, therapy, and communication at the disposal of medicine in general, and of critical care in particular. The art of healing requires not only technical proficiency, but also personal connection, multidisciplinary teamwork, and commitment to the ve...

journal_title：Critical care (London, England)

authors： Marini JJ

更新日期：2015-01-01 00:00:00

abstract：:In this month's issue of Critical Care, Determann and colleagues report the results of a randomized controlled trial comparing the effects of mechanical ventilation (MV) with two tidal volumes (6 versus 10 ml/kg predicted body weight) on cytokine levels in lung lavage fluid and plasma as a surrogate for early identifi...

journal_title：Critical care (London, England)

authors： Villar J,Slutsky AS

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Survival after cadaveric lung transplantation (LTx) in respiratory failure recipients who were already dependent on ventilation support prior to transplantation is poor, with a relatively high rate of surgical mortality and morbidity. In this study, we sought to describe the short-term outcomes of bilatera...

journal_title：Critical care (London, England)

authors： Hsu HH,Chen JS,Ko WJ,Huang SC,Kuo SW,Huang PM,Chi NH,Chang CC,Chen RJ,Lee YC

更新日期：2009-01-01 00:00:00

abstract：:Two international multicentre randomised controlled trials of drotrecogin alfa (activated) (DrotAA), the Recombinant Human Activated Protein C Worldwide Evaluation of Severe Sepsis (PROWESS) and Administration of Drotrecogin Alfa (Activated) in Early Stage Severe Sepsis (ADDRESS) trials, have produced inconsistent res...

journal_title：Critical care (London, England)

authors： Friedrich JO,Adhikari NK,Meade MO

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Staphylococcus (S.) aureus has emerged as an important cause of necrotizing pneumonia. Lung injury during S. aureus pneumonia may be enhanced by local release of damage associated molecular patterns such as high-mobility group box 1 (HMGB1). In the current study we sought to determine the functional role o...

journal_title：Critical care (London, England)

authors： Achouiti A,van der Meer AJ,Florquin S,Yang H,Tracey KJ,van 't Veer C,de Vos AF,van der Poll T

更新日期：2013-12-16 00:00:00

abstract：BACKGROUND:Recurrent delivery of tidal mechanical energy (ME) inflicts ventilator-induced lung injury (VILI) when stress and strain exceed the limits of tissue tolerance. Mechanical power (MP) is the mathematical description of the ME delivered to the respiratory system over time. It is unknown how ME relates to underl...

journal_title：Critical care (London, England)

authors： Kneyber MCJ,Ilia S,Koopman AA,van Schelven P,van Dijk J,Burgerhof JGM,Markhorst DG,Blokpoel RGT

更新日期：2020-10-07 00:00:00

abstract：INTRODUCTION:Severe acute pancreatitis (SAP) requiring admission to a critical care unit is associated with high mortality and long lengths of stay. We describe the case mix, outcome, and activity of admissions with SAP who were identified from a high-quality clinical database. METHODS:We conducted a secondary analysi...

journal_title：Critical care (London, England)

authors： Harrison DA,D'Amico G,Singer M

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to investigate whether common variants across the nuclear factor erythroid 2-like 2 (NFE2L2) gene contribute to the development of the acute respiratory distress syndrome (ARDS) in patients with severe sepsis. NFE2L2 is involved in the response to oxidative stress, and it has ...

journal_title：Critical care (London, England)

authors： Acosta-Herrera M,Pino-Yanes M,Blanco J,Ballesteros JC,Ambrós A,Corrales A,Gandía F,Subirá C,Domínguez D,Baluja A,Añón JM,Adalia R,Pérez-Méndez L,Flores C,Villar J,GRECIA and GEN-SEP networks.

更新日期：2015-06-16 00:00:00

abstract：BACKGROUND:There is increasing interest in the timely administration of concentrated sources of fibrinogen to patients with major traumatic bleeding. Following evaluation of early cryoprecipitate in the CRYOSTAT 1 trial, we explored the use of fibrinogen concentrate, which may have advantages of more rapid administrati...

journal_title：Critical care (London, England)

authors： Curry N,Foley C,Wong H,Mora A,Curnow E,Zarankaite A,Hodge R,Hopkins V,Deary A,Ray J,Moss P,Reed MJ,Kellett S,Davenport R,Stanworth S

更新日期：2018-06-18 00:00:00

abstract：:Base deficit has frequently been utilized as an informal adjunct in the initial evaluation of trauma patients to assess the extent of their physiologic derangements. However, the current Advanced Trauma Life Support (ATLS) classification system for hypovolemic shock does not include base-deficit measurements and relie...

journal_title：Critical care (London, England)

authors： Privette AR,Dicker RA

更新日期：2013-03-13 00:00:00

abstract：:Facilitation of early spontaneous breathing activity is the most important measure to shorten weaning and avoid ventilator-induced lung injury and diaphragmatic injury in mechanically ventilated patients. However, the optimal degree of spontaneous muscle activity and ventilator support remains to be determined. Furthe...

journal_title：Critical care (London, England)

authors： Calzia E,Dembinski R

更新日期：2013-11-19 00:00:00

abstract：INTRODUCTION:The present study assessed the opinion of general practitioners (GPs) concerning their relationships with intensivists. METHODS:An anonymous questionnaire was mailed to 7,239 GPs. GPs were asked about their professional activities, postgraduate intensive care unit (ICU) training, the rate of patient admit...

journal_title：Critical care (London, England)

authors： Etesse B,Jaber S,Mura T,Leone M,Constantin JM,Michelet P,Zoric L,Capdevila X,Malavielle F,Allaouchiche B,Orban JC,Fabbro-Peray P,Lefrant JY,AzuRéa Group.

更新日期：2010-01-01 00:00:00

abstract：:Considerable progress has been made recently in the understanding of how best to accomplish safe and effective ventilation of patients with acute lung injury. Mechanical and nonmechanical factors contribute to causation of ventilator-associated lung injury. Intervention timing helps determine the therapeutic efficacy ...

journal_title：Critical care (London, England)

authors： Marini JJ

更新日期：2015-01-01 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2020. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2020. Further information about the Annual Update in Intensive Care and Emergency Medicine is available ...

journal_title：Critical care (London, England)

authors： Bassetti M,Bandera A,Gori A

更新日期：2020-03-24 00:00:00

abstract：:Mechanotransduction holds the underlying mechanisms of ventilator-induced lung injury. Research on this subject, however, could be difficult for clinicians, especially when results are controversial. A recent study by Li and co-workers is used as an example, to explain how to critically read literatures related to bas...

journal_title：Critical care (London, England)

authors： Liu M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Despite quick implementation of reperfusion therapies, a few patients with high-risk, acute, massive, pulmonary embolism (PE) remain highly hemodynamically unstable. Others have absolute contraindication to receive reperfusion therapies. Venoarterial-extracorporeal membrane oxygenation (VA-ECMO) might lower ...

journal_title：Critical care (London, England)

authors： Corsi F,Lebreton G,Bréchot N,Hekimian G,Nieszkowska A,Trouillet JL,Luyt CE,Leprince P,Chastre J,Combes A,Schmidt M

更新日期：2017-03-28 00:00:00

abstract：INTRODUCTION:Angiopoietin-2 (ang-2), an angiogenic peptide released by endothelial cell Weibel-Palade bodies (WPBs), increases endothelial activation and vascular permeability. Ang-2 is raised in severe sepsis but the mechanisms underlying this are not known. Nitric oxide (NO) inhibits WPB exocytosis, and bioavailabili...

journal_title：Critical care (London, England)

authors： Davis JS,Yeo TW,Piera KA,Woodberry T,Celermajer DS,Stephens DP,Anstey NM

更新日期：2010-01-01 00:00:00