Abstract：
:Natural products are evolutionarily designed and chemically distinct from most synthetic library molecules. In addition to their role as drugs, they are successfully used as molecular probes to identify disease relevant targets. Novel natural products are still routinely discovered from traditional sources through cultivation of microorganisms. Complementary approaches based on genome sequence information and subsequent annotation of biosynthetic pathways are emerging technologies. However, to be of practical use for drug discovery, these concepts must be advanced beyond their current state.
journal_name
Curr Opin Chem Bioljournal_title
Current opinion in chemical biologyauthors
Schmitt EK,Moore CM,Krastel P,Petersen Fdoi
10.1016/j.cbpa.2011.05.018subject
Has Abstractpub_date
2011-08-01 00:00:00pages
497-504issue
4eissn
1367-5931issn
1879-0402pii
S1367-5931(11)00087-1journal_volume
15pub_type
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journal_title：Current opinion in chemical biology
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journal_title：Current opinion in chemical biology
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journal_title：Current opinion in chemical biology
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journal_title：Current opinion in chemical biology
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journal_title：Current opinion in chemical biology
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journal_title：Current opinion in chemical biology
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journal_title：Current opinion in chemical biology
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journal_title：Current opinion in chemical biology
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journal_title：Current opinion in chemical biology
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journal_title：Current opinion in chemical biology
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journal_title：Current opinion in chemical biology
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journal_title：Current opinion in chemical biology
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