Cardiovascular consequences of extreme prematurity: the EPICure study.

Abstract:

OBJECTIVES:The long-term consequences of extreme prematurity are becoming increasingly important, given recent improvements in neonatal intensive care. The aim of the current study was to examine the cardiovascular consequences of extreme prematurity in 11-year-olds born at or before 25 completed weeks of gestation. METHODS:Age and sex-matched classmates were recruited as controls. Information concerning perinatal and maternal history was collected, and current anthropometric characteristics were measured in 219 children born extremely preterm and 153 classmates. A subset of the extremely preterm children (n = 68) and classmates (n = 90) then underwent detailed haemodynamic investigations, including measurement of supine blood pressure (BP), aortic pulse wave velocity (aPWV, a measure of aortic stiffness) and augmentation index (AIx, a measure of arterial pressure wave reflections). RESULTS:Seated brachial systolic and diastolic BP were not different between extremely preterm children and classmates (P = 0.3 for both), although there was a small, significant elevation in supine mean and diastolic BP in the extremely preterm children (P < 0.05 for both). Arterial pressure wave reflections were significantly elevated in the extremely preterm children (P < 0.001) and this persisted after adjusting for confounding variables. However, aortic stiffness was not different between the groups (P = 0.1). CONCLUSIONS:These data suggest that extreme prematurity is associated with altered arterial haemodynamics in children, not evident from the examination of brachial BP alone. Moreover, the smaller, preresistance and resistance vessels rather than large elastic arteries appear to be most affected. Children born extremely preterm may be at increased future cardiovascular risk.

journal_name

J Hypertens

journal_title

Journal of hypertension

authors

McEniery CM,Bolton CE,Fawke J,Hennessy E,Stocks J,Wilkinson IB,Cockcroft JR,Marlow N

doi

10.1097/HJH.0b013e328347e333

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

1367-73

issue

7

eissn

0263-6352

issn

1473-5598

journal_volume

29

pub_type

杂志文章
  • Variation in cuff blood pressure in untreated outpatients with mild hypertension--implications for initiating antihypertensive treatment.

    abstract::Thirty-two patients with mildly elevated blood pressure (BP), but without target organ damage, attended a BP measuring clinic where duplicate BP measurements were made on 12 visits. During visits 1-3, BP showed a systematic decrease which varied from patient to patient. During visits 4-12, no further systematic change...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198704000-00012

    authors: Watson RD,Lumb R,Young MA,Stallard TJ,Davies P,Littler WA

    更新日期:1987-04-01 00:00:00

  • Relationship of renal histological damage to glomerular hypertension in patients with immunoglobulin A nephropathy.

    abstract:OBJECTIVE:Studies of experimental animals show glomerular hypertension to be important in the progression of glomerular disease. We evaluated this connection clinically by examining the relationship between glomerular hemodynamics and histological changes in patients with immunoglobulin (Ig)A nephropathy. METHODS:The ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200018010-00015

    authors: Konishi Y,Imanishi M,Okamura M,Yoshioka K,Okumura M,Okada N,Tanaka S,Fujii S,Kimura G

    更新日期:2000-01-01 00:00:00

  • Patterns of treatment modifications among newly treated hypertensive patients: does choice of modification strategy affect likelihood of treatment discontinuation?

    abstract:OBJECTIVES:Treatment modifications--addition, uptitration, switching, and downtitration--are necessary to address issues such as unattained blood pressure goals, adverse drug events, drug cost, or patient dissatisfaction which lead to treatment discontinuation. This study assessed the patterns of treatment modification...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000000806

    authors: Sonawane KB,Qian J,Garza KB,Wright BM,Zeng P,Ganduglia-Cazaban CM,Hansen RA

    更新日期:2016-03-01 00:00:00

  • Pressor responses to laboratory stresses and daytime blood pressure variability.

    abstract::We studied 56 patients with essential hypertension to determine whether responses to standardized laboratory mental and physical challenges accurately reflect blood pressure variability during routine daily activities. Four activities were performed in the laboratory: mental arithmetic, a reaction time test, isometric...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198712000-00014

    authors: Floras JS,Hassan MO,Jones JV,Sleight P

    更新日期:1987-12-01 00:00:00

  • Evidence that human endothelial cells express different isoforms of Na,K-ATPase.

    abstract:BACKGROUND:The catalytic alpha and smaller beta subunits of the plasma membrane Na,K-ATPase occur in various molecular forms (alpha1, alpha2, alpha3, beta1 and beta2). The alpha isoforms of the enzyme have varying affinities for ouabain and exist in different tissues with particular distribution patterns. OBJECTIVE:To...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199816020-00003

    authors: Mayol V,Dignat-George F,Gerbi A,Martin-Vasallo P,Lesaule G,Sampol J,Maixent JM

    更新日期:1998-02-01 00:00:00

  • Dipyridamole-atropine stress echocardiography versus exercise SPECT scintigraphy for detection of coronary artery disease in hypertensives with positive exercise test.

    abstract:OBJECTIVES:Many different stress echocardiographic and radionuclide perfusion imaging tests have been proposed for detecting epicardial coronary artery disease (CAD) in hypertensive patients. Their relative diagnostic and prognostic value has not been exactly established. BACKGROUND:A positive exercise electrocardiogr...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200103000-00018

    authors: Astarita C,Pálinkás A,Nicolai E,Maresca FS,Varga A,Picano E

    更新日期:2001-03-01 00:00:00

  • Exercise training delays renal disorders with decreasing oxidative stress and increasing production of 20-hydroxyeicosatetraenoic acid in Dahl salt-sensitive rats.

    abstract:OBJECTIVE:Exercise training has antihypertensive and renoprotective effects in humans and rats. However, the effects of exercise training on renal disorders that occur with salt-sensitive hypertension remains unclear. The study aim was to investigate the effects and mechanisms of exercise training on renal function in ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000002409

    authors: Ogawa Y,Takahashi J,Sakuyama A,Xu L,Miura T,Muroya Y,Ito D,Kohzuki M,Ito O

    更新日期:2020-07-01 00:00:00

  • Optimizing observer performance of clinic blood pressure measurement: a position statement from the Lancet Commission on Hypertension Group.

    abstract::: High blood pressure (BP) is a highly prevalent modifiable cause of cardiovascular disease, stroke, and death. Accurate BP measurement is critical, given that a 5-mmHg measurement error may lead to incorrect hypertension status classification in 84 million individuals worldwide. This position statement summarizes pro...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,实务指引

    doi:10.1097/HJH.0000000000002112

    authors: Padwal R,Campbell NRC,Schutte AE,Olsen MH,Delles C,Etyang A,Cruickshank JK,Stergiou G,Rakotz MK,Wozniak G,Jaffe MG,Benjamin I,Parati G,Sharman JE

    更新日期:2019-09-01 00:00:00

  • Renal angioplasty: better for treating hypertension or for rescuing renal function?

    abstract::Angioplasty of renal artery stenosis has been used extensively in the last two decades for treating renovascular hypertension, and, more recently, for preserving the jeopardized renal function. A large body of evidence has accumulated indicating that this approach is by far the most convenient for patients with fibrom...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,评审

    doi:10.1097/00004872-199917120-00001

    authors: Morganti A

    更新日期:1999-12-01 00:00:00

  • Chronic antioxidant treatment improves sympathetic functions and beta-adrenergic pathway in the spontaneously hypertensive rats.

    abstract:BACKGROUND:Correlations have been found between oxidative stress and hypertension. OBJECTIVE:To determine whether antioxidants can normalize sympathetic dysfunction at pre- or postsynaptic levels in spontaneously hypertensive rats (SHRs). METHODS AND RESULTS:Untreated SHRs and Wistar-Kyoto (WKY) rats were compared wi...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200301000-00028

    authors: Girouard H,Chulak C,LeJossec M,Lamontagne D,de Champlain J

    更新日期:2003-01-01 00:00:00

  • Effects of urban noise pollution on blood pressure and heart rate in preschool children.

    abstract:OBJECTIVE:To investigate the association between long-term exposure to high-level urban traffic noise and blood pressure in preschool children. DESIGN:Normotensive children (n = 1542), aged 3-7 years and attending kindergartens, had their blood pressures and heart rate measured. Mean values of these circulatory variab...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:

    authors: Regecová V,Kellerová E

    更新日期:1995-04-01 00:00:00

  • Spectral analysis of the systolic blood pressure signal in secondary hypertension: a method for the identification of phaeochromocytoma.

    abstract:OBJECTIVE:To seek in hypertensive patients rhythmic variations of the systolic blood pressure signal obtained by ambulatory blood pressure monitoring of any inherent cycle of intermediate value between 1 and 24 h. DESIGN:Subjects (62 hypertensive, 39 normotensive) were evaluated by 24-h ambulatory blood pressure monit...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:

    authors: Meisel SR,Mor-Avi V,Rosenthal T,Akselrod S

    更新日期:1994-03-01 00:00:00

  • Genetic heterogeneity of familial hyperkalaemic hypertension.

    abstract:BACKGROUND:Familial hyperkalaemic hypertension (FHH) is a Mendelian form of low-renin hypertension characterized by hyperkalaemia and hyperchloraemic acidosis despite a normal glomerular filtration rate. To date, three different loci have been identified, on chromosomes 1, 17 and 12. OBJECTIVE:To test for genetic link...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200111000-00005

    authors: Disse-Nicodeme S,Desitter I,Fiquet-Kempf B,Houot AM,Stern N,Delahousse M,Potier J,Ader JL,Jeunemaitre X

    更新日期:2001-11-01 00:00:00

  • Contribution of reactive oxygen species to the pathogenesis of left ventricular failure in Dahl salt-sensitive hypertensive rats: effects of angiotensin II blockade.

    abstract:OBJECTIVE:We investigated the contribution of reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase-dependent reactive oxygen species (ROS) generation to the pathogenesis of diastolic heart failure (DHF) in Dahl salt-sensitive (DS) hypertensive rats, with the aim of testing our hypothesis that the cardiop...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000226200.73065.5d

    authors: Guo P,Nishiyama A,Rahman M,Nagai Y,Noma T,Namba T,Ishizawa M,Murakami K,Miyatake A,Kimura S,Mizushige K,Abe Y,Ohmori K,Kohno M

    更新日期:2006-06-01 00:00:00

  • Identification of salt-sensitive genes in the kidneys of Dahl rats.

    abstract:OBJECTIVE:Inherited differences in renal function underlie the effect of high salt diets on blood pressure in Dahl rats. We probed the kidneys of inbred Dahl SS/Jr and SR/Jr for anonymous and candidate genes whose expression was regulated by dietary sodium. METHODS:mRNA quantitation of both candidate genes implicated ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000133719.94075.e2

    authors: Lighthall GK,Hamilton BP,Hamlyn JM

    更新日期:2004-08-01 00:00:00

  • Norepinephrine overflow and re-uptake in perfused mesenteric arteries of Dahl salt-sensitive and salt-resistant rats.

    abstract::We compared the overflow of endogenous norepinephrine (NE) upon electrical stimulation, the associated pressor response and rate of initial neuronal uptake of 3H-I-NE in the perfused mesenteric arteries of Dahl salt-sensitive (DS) and salt-resistant (DR) rats on two dietary NaCl regimens (0.4 and 8.0% for 2 weeks) fro...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-198901000-00007

    authors: Hano T,Jeng Y,Rho J

    更新日期:1989-01-01 00:00:00

  • Effect of anticipation and cuff inflation on blood pressure during self-measurement.

    abstract:BACKGROUND:Self-measurement of blood pressure (BP) is increasingly being used for the diagnosis of hypertension and to monitor BP at home. Whenever compared with ambulatory BP measurements, home BP values are frequently higher and less predictive for incident cardiovascular events. We hypothesized that this could be ca...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001775

    authors: Gazzola K,Honingh M,Truijen J,Zuliani G,Van Den Born BH

    更新日期:2018-09-01 00:00:00

  • Assessment of prevalence of left ventricular hypertrophy in hypertension.

    abstract::The reported prevalence of left ventricular hypertrophy (LVH) in human hypertension is much lower than that among animals with experimental hypertension. With current methods of determining left ventricular mass by M-mode echocardiography, the standard error of a single estimate is high and consequently so is the SD o...

    journal_title:Journal of hypertension

    pub_type: 社论,评审

    doi:10.1097/00004872-199816060-00001

    authors: Korner PI,Jennings GL

    更新日期:1998-06-01 00:00:00

  • Alcohol intake and cardiovascular mortality in hypertensive patients: report from the Department of Health Hypertension Care Computing Project.

    abstract:OBJECTIVE:To determine the benefits and risks of drinking alcohol in treated hypertensives. DESIGN:A prospective study of 6,369 hypertensives (3,161 men) attending primarily hospital clinics in the UK. METHODS:Relative risks both for drinkers compared with non-drinkers and for level of alcohol consumption were calcul...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199509000-00004

    authors: Palmer AJ,Fletcher AE,Bulpitt CJ,Beevers DG,Coles EC,Ledingham JG,Petrie JC,Webster J,Dollery CT

    更新日期:1995-09-01 00:00:00

  • The treatment of obese hypertensive black women: a comparative study of chlorthalidone versus clonidine.

    abstract:OBJECTIVE:We attempted to determine a valid pharmacological approach for the control of high blood pressure in obese hypertensive patients using two antihypertensive agents with different pharmacological actions. DESIGN:Thirty-two obese hypertensive black women were randomly treated with chlorthalidone or clonidine to...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004872-199205000-00013

    authors: Reisin E,Weed SG

    更新日期:1992-05-01 00:00:00

  • Molecular forms of plasma and urinary adrenomedullin in normal, essential hypertension and chronic renal failure.

    abstract:OBJECTIVES:Human adrenomedullin precursor is converted to glycine-extended adrenomedullin (AM-Gly), an intermediate inactive form of adrenomedullin. Subsequently, AM-Gly is converted to active form of mature adrenomedullin (AM-m). The aim of the present study was to investigate (i) whether sex or age influences plasma ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-200104000-00014

    authors: Nishikimi T,Horio T,Kohmoto Y,Yoshihara F,Nagaya N,Inenaga T,Saito M,Teranishi M,Nakamura M,Ohrui M,Kawano Y,Matsuo H,Ishimitsu T,Takishita S,Matsuoka H,Kangawa K

    更新日期:2001-04-01 00:00:00

  • Effect of self-measurement of blood pressure on adherence to treatment in patients with mild-to-moderate hypertension.

    abstract:BACKGROUND:Poor adherence to treatment is one of the major problems in the treatment of hypertension. Self blood pressure measurement may help patients to improve their adherence to treatment. METHOD:In this prospective, randomized, controlled study coordinated by a university hospital, a total of 228 mild-to-moderate...

    journal_title:Journal of hypertension

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/HJH.0b013e328334f36b

    authors: van Onzenoort HA,Verberk WJ,Kroon AA,Kessels AG,Nelemans PJ,van der Kuy PH,Neef C,de Leeuw PW

    更新日期:2010-03-01 00:00:00

  • P2X7 receptor polymorphisms do not influence endothelial function and vascular tone in neo-diagnosed, treatment-naive essential hypertensive patients.

    abstract:OBJECTIVE:Endothelial dysfunction and arterial stiffness are early vascular alterations, linked to oxidative stress and inflammation, with prognostic significance in essential hypertensive patients. P2X7 receptors (P2X7R), responding to extracellular ATP, are encoded by a highly polymorphic gene and modulate inflammato...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e3283653ff5

    authors: Ghiadoni L,Rossi C,Duranti E,Santini E,Bruno RM,Salvati A,Taddei S,Solini A

    更新日期:2013-12-01 00:00:00

  • Changes of blood pressure patterns and target organ damage in patients with chronic kidney disease: results of the APrODiTe-2 study.

    abstract:OBJECTIVE:Blood pressure (BP) control is the most established practice for preventing the progression of chronic kidney disease (CKD). We examined the BP control and nocturnal dipping pattern changes in hypertensive patients with CKD and their effects on target organ damages. METHODS:We recruited 378 hypertensive CKD ...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0000000000001185

    authors: Cha RH,Lee H,Lee JP,Kang E,Song YR,Kim YS,Kim SG

    更新日期:2017-03-01 00:00:00

  • Early cardiac gene transcript levels in peripheral blood mononuclear cells in patients with untreated essential hypertension.

    abstract:OBJECTIVES:To assess the expression of early cardiac genes, implicated in the hypertrophic growth response of the adult heart, in peripheral blood mononuclear cells in patients with essential hypertension and its relationship to ambulatory blood pressure monitoring (ABPM) parameters and to echocardiographic left ventri...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e3283424bc4

    authors: Kontaraki JE,Marketou ME,Zacharis EA,Parthenakis FI,Vardas PE

    更新日期:2011-04-01 00:00:00

  • The response of renal plasma flow to angiotensin II infusion in a population-based sample and its association with the parental history of essential hypertension.

    abstract:BACKGROUND:Results from previous studies suggested that a blunted response of renal plasma flow (RPF) to angiotensin II infusion during a high-sodium diet (a phenotype associated with nonmodulation) is an intermediate phenotype for essential hypertension. OBJECTIVE:To determine whether RPF traits used to investigate n...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/00004872-199715050-00003

    authors: Kardia SL,Sing CF,Turner ST

    更新日期:1997-05-01 00:00:00

  • Insulin resistance in hypertensives: effect of salt sensitivity, renin status and sodium intake.

    abstract:OBJECTIVE:Homeostasis Model Assessment (HOMA index) is predictive of insulin sensitivity in normal and diabetic patients. This study was designed to see if insulin resistance in hypertensives, measured using the HOMA index, differs, based on salt sensitivity, renin status and sodium intake. METHODS:Fasting insulin and...

    journal_title:Journal of hypertension

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1097/00004872-200101000-00013

    authors: Raji A,Williams GH,Jeunemaitre X,Hopkins PN,Hunt SC,Hollenberg NK,Seely EW

    更新日期:2001-01-01 00:00:00

  • Blood pressure and the global burden of disease 2000. Part II: estimates of attributable burden.

    abstract:OBJECTIVES:To provide estimates of the global burden of disease attributable to non-optimal blood pressure by age and sex for adults aged > or = 30 years, by WHO subregion. METHODS:Estimates of attributable burden were made using population impact fractions, which used data on mean systolic blood pressure levels, dise...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000209973.67746.f0

    authors: Lawes CM,Vander Hoorn S,Law MR,Elliott P,MacMahon S,Rodgers A

    更新日期:2006-03-01 00:00:00

  • Pulse wave velocity is increased in patients with transient myocardial ischemia.

    abstract:OBJECTIVE:We have recently shown that mean pulse pressure is higher in patients with transient myocardial ischemia. Pulse pressure elevation might be an important consequence of increased arterial stiffness. The aim of this study was to prove if arterial stiffness is changed in patients with transient myocardial ischem...

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/01.hjh.0000244959.92856.7e

    authors: Baulmann J,Homsi R,Uen S,Düsing R,Fimmers R,Vetter H,Mengden T

    更新日期:2006-10-01 00:00:00

  • Blood pressure in early adolescence in the offspring of preeclamptic and normotensive pregnancies.

    abstract:OBJECTIVE:To compare blood pressure (BP) in adolescence (11-12 years) among the offspring of preeclamptic and normotensive pregnancies. METHOD:SBP and DBP of 181 girls and boys born after pregnancies with preeclampsia were measured and compared with the BP of 356 age-matched girls and boys of normotensive pregnancies....

    journal_title:Journal of hypertension

    pub_type: 杂志文章

    doi:10.1097/HJH.0b013e328330052a

    authors: Øglaend B,Forman MR,Romundstad PR,Nilsen ST,Vatten LJ

    更新日期:2009-10-01 00:00:00