Norepinephrine overflow and re-uptake in perfused mesenteric arteries of Dahl salt-sensitive and salt-resistant rats.

abstract：OBJECTIVES:To assess the influence of sodium intake on the two components of arterial blood pressure [mean blood pressure (MBP) and pulse pressure] and left ventricular mass (LVM) in normotensive subjects and never-treated hypertensive patients. METHODS:Blood pressure, LVM (M-mode echocardiography) and sodium excretio...

journal_title：Journal of hypertension

authors： du Cailar G,Mimran A,Fesler P,Ribstein J,Blacher J,Safar ME

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVES:Studies regarding the effects of parity on blood pressure in later life produced conflicting results. The aim of our study is to analyse whether parity influences the prevalence of hypertension in perimenopausal and postmenopausal women. METHODS:One thousand perimenopausal and postmenopausal women (mean age...

journal_title：Journal of hypertension

authors： Giubertoni E,Bertelli L,Bartolacelli Y,Origliani G,Modena MG

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To explore the repercussion of cardiac denervation on the short-term blood pressure variability in humans, in order to assess the extent to which the variability of blood pressure is linked to the variability of heart rate. METHODS:Beat-to-beat blood pressure and RR interval time were recorded in 16 heart-tr...

journal_title：Journal of hypertension

authors： van de Borne P,Schintgen M,Niset G,Schoenfeld P,Nguyen H,Degré S,Degaute JP

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVES:Recent studies in homogenized hearts suggest that chymase rather than angiotensin converting enzyme (ACE) is responsible for cardiac angiotensin I to angiotensin II conversion. We investigated in intact rat hearts whether (i) enzymes other than ACE contribute to angiotensin I to angiotensin II conversion and...

journal_title：Journal of hypertension

authors： de Lannoy LM,Schuijt MP,Saxena PR,Schalekamp MA,Danser AH

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Chronic diabetes is associated with alterations in autonomic modulation of the cardiovascular system. Although the rat has been used extensively in studies of experimental diabetes, there have been no reports on the changes in autonomic modulation of the cardiovascular function in chronic diabetic rats. OBJ...

journal_title：Journal of hypertension

authors： Fazan R Jr,Dias da Silva VJ,Ballejo G,Salgado HC

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:We examined the relation between cardiovascular reactivity (the response of the cardiovascular system to psychological stress) and the severity and progression of carotid atherosclerosis. METHODS:Using duplex ultrasonography, we measured the change in the area of all detectable plaques in the extracranial c...

journal_title：Journal of hypertension

authors： Barnett PA,Spence JD,Manuck SB,Jennings JR

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:High blood pressure is known to be associated with higher cardiovascular risk. The emphasis has shifted over time from diastolic pressure to systolic pressure and variability in blood pressure. This study examined the impact of transient and sustained diastolic hypertension on later mortality. METHODS:In th...

journal_title：Journal of hypertension

authors： Peters R,Wells F,Bulpitt C,Beckett N

更新日期：2013-01-01 00:00:00

abstract：:To assess the role of renal prostaglandin E in the hypotensive mechanism of MK-421, we evaluated the effects of chronic infusion of MK-421 (6 mg/kg/day i.p.) on systolic blood pressure and urinary prostaglandin E excretion in conscious rats in states of sodium repletion or depletion and also during chronic infusion of...

journal_title：Journal of hypertension

authors： Yasujima M,Abe K,Tanno M,Kasai Y,Sato K,Tajima J,Kudo K,Tsunoda K,Yoshinaga K

更新日期：1984-12-01 00:00:00

abstract：:This study focuses on the relationship between some aspects of intra-erythrocytic sodium metabolism (intra-erythrocytic Na content, Na,Li-countertransport), blood pressure, and family history of hypertension, in a group of 84 randomly selected school children (45 males, 39 females). Na,Li-countertransport was signific...

journal_title：Journal of hypertension

authors： Trevisan M,Strazzullo P,Cappuccio FP,Di Muro MR,De Colle S,Franzese A,Iacone R,Krogh V

更新日期：1988-03-01 00:00:00

abstract：:Conscious male beagle dogs were given constant intravenous infusions of noradrenaline for 14 days, four receiving 125 ng/kg/min and four 250 ng/kg/min. Before, during and after these infusions dose-response studies were done in which additional noradrenaline was infused at 500, 1000 and 2000 ng/kg/min, each rate for 1...

journal_title：Journal of hypertension

authors： Casals-Stenzel J,Tree M,Brown JJ,Fraser R,Lever AF,Millar JA,Morton JJ,Robertson JI,Reid JL,Hamilton C

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism-related differences in ACE concentration do not result in differences in angiotensin levels. METHODS AND RESULTS:To investigate whether this relates to differences in the contribution of the ACE C-domain and N-domain, we quantified, u...

journal_title：Journal of hypertension

authors： van Esch JH,van Gool JM,de Bruin RJ,Payne JR,Montgomery HE,Hectors M,Deinum J,Dive V,Jan Danser AH

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:To determine prevalence, awareness, treatment, and control of hypertension, and its risk factors in an urban Korean population. DESIGN AND SETTING:A cross-sectional survey in Ansan-city, Korea. SUBJECTS AND METHODS:Population-based samples of people aged 18-92 years in Ansan-city, Korea, were selected, yie...

journal_title：Journal of hypertension

authors： Jo I,Ahn Y,Lee J,Shin KR,Lee HK,Shin C

更新日期：2001-09-01 00:00:00

abstract：:Hypertension is associated with thickening of the wall of resistance vessels, but the cellular or genetic basis of this is unclear. Cell proliferation and intracellular alkalinization via increased Na+/H+ exchange are linked in the response of tissues to growth factors. To define a possible cellular basis for vascular...

journal_title：Journal of hypertension

authors： Ng LL,Dudley C,Bomford J,Hawley D

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence of episodes of ST-segment depression in a population of consecutive patients with mild-to-moderate essential hypertension who are free of clinical signs of coronary artery disease. METHODS:The study involved 28 Italian centers that enrolled 414 hypertensive patients (aged 50-70 year...

journal_title：Journal of hypertension

authors： Stramba-Badiale M,Bonazzi O,Casadei G,Dal Palù C,Magnani B,Zanchetti A

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the association of angiotensinogen (AGT) gene with AGT level and hypertension based on the overall genetic variation of the AGT gene in among African-Americans. METHODS:All non-rare single nucleotide polymorphisms (SNPs) in AGT were identified by resequencing 24 individuals. Five tagging SNPs wer...

journal_title：Journal of hypertension

authors： Wu X,Luke A,Rieder M,Lee K,Toth EJ,Nickerson D,Zhu X,Kan D,Cooper RS

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:To determine whether vigorous exercise and alcohol restriction have additive and independent effects in reducing blood pressure in sedentary male alcohol drinkers. Also to assess whether 4 weeks of vigorous exercise could offset the fall in high-density lipoprotein cholesterol (HDL-cholesterol) usually obser...

journal_title：Journal of hypertension

authors： Cox KL,Puddey IB,Morton AR,Beilin LJ,Vandongen R,Masarei JR

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVE:To examine the effect on quality of life in hypertensive men of a multiple risk factor intervention programme compared with that of usual care. DESIGN:A prospective, open, randomized, parallel-group study with allocation either to a comprehensive multiple risk factor modification programme or to usual care. ...

journal_title：Journal of hypertension

authors： Agewall S,Wikstrand J,Dahlöf C,Fagerberg B

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Fibromuscular dysplasia (FMD) and atherosclerotic renal artery stenosis (ARAS) are the most common causes of renovascular hypertension. So far, FMD is believed to cause hypertension via similar mechanisms as in ARAS, that is, a decrease in renal blood flow, which subsequently leads to increased renin secreti...

journal_title：Journal of hypertension

authors： van Twist DJ,Houben AJ,de Haan MW,de Leeuw PW,Kroon AA

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND AND AIM:Central blood pressure (BP) is increasingly considered as a better estimator of hypertension associated risks. We aimed to evaluate the association of 24-h central BP, in comparison with 24-h peripheral BP, with the presence of target organ damage (TOD). METHODS:Cross-sectional study of 208 hyperten...

journal_title：Journal of hypertension

authors： de la Sierra A,Pareja J,Fernández-Llama P,Armario P,Yun S,Acosta E,Calero F,Vázquez S,Blanch P,Sierra C,Oliveras A

更新日期：2017-10-01 00:00:00

abstract：:Ca2+ pump kinetics were investigated in erythrocytes from 22 essential hypertensive patients and 20 normotensive controls (under initial-rate and steady-state conditions, using Sr2+ as a Ca2+ analogue). The mean value of the apparent dissociation constant for total internal Ca2+ (KCa) was slightly but significantly in...

journal_title：Journal of hypertension

authors： de la Sierra A,Hannaert P,Ollivier JP,Senn N,Garay R

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVE:A number of potential interactions between angiotensin-converting enzyme inhibitors and lithium have been described in the literature. In the present study, we investigated the effects of a low-dose combination treatment with lithium and captopril on survival and stroke prevention in salt-loaded, stroke-prone...

journal_title：Journal of hypertension

authors： Xu J,Scholz A,Rösch N,Blume A,Unger T,Kreutz R,Culman J,Gohlke P

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVES:Nonsteroidal anti-inflammatory drugs vary in their impact on blood pressure and the effect of lumiracoxib 100 mg once daily has not been studied previously. To examine whether lumiracoxib 100 mg once daily would result in lower 24-h mean systolic ambulatory blood pressure than ibuprofen 600 mg three times da...

journal_title：Journal of hypertension

authors： MacDonald TM,Reginster JY,Littlejohn TW,Richard D,Lheritier K,Krammer G,Rebuli R

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVES:Local atrial tissue angiotensin II (AngII) level is elevated in atrial fibrillation (AF), but the mechanism is unknown. We hypothesized that atrial myocytes express all components of the renin-angiotensin system (RAS) and investigated whether rapid depolarization alone is sufficient to increase paracrine Ang...

journal_title：Journal of hypertension

authors： Tsai CT,Lai LP,Hwang JJ,Chen WP,Chiang FT,Hsu KL,Tseng CD,Tseng YZ,Lin JL

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:Adenosine dilates rabbit renal arteries by an endothelium-dependent, nitric oxide (NO)- and prostaglandin-independent mechanism. The aim was to identify the responsible P1-purinoceptor subtype and to investigate the involvement of K+-channels. METHODS:Rabbit renal arteries were perfused with medium containin...

journal_title：Journal of hypertension

authors： Rump LC,Jabbari-T J,von Kügelgen I,Oberhauser V

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To determine whether a diuretic can also reverse the clinical, systemic, renal and glomerular haemodynamic and pathological changes caused by nephrosclerosis. METHODS:Three groups of 20-week-old spontaneously hypertensive rats (SHR) were investigated: control male SHR; a similar group, administered 50 mg/l N...

journal_title：Journal of hypertension

authors： Ono Y,Ono H,Frohlich ED

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:Different radiologists may show considerable variation in their interpretation of renal angiograms. We therefore wished to establish the reliability of their interpretation. DESIGN:Assessment of the intra- and inter-observer agreement of the interpretation of renal angiograms. SETTING:Tertiary referral univ...

journal_title：Journal of hypertension

authors： Schreij G,de Haan MW,Oei TK,Koster D,de Leeuw PW

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus is associated with an increased risk of hypertension, and cardiovascular and renal disease, and it has been recommended that management of hypertension should be more aggressive in presence than in absence of diabetes mellitus, but the matter is controversial at present. OBJECTIVES:...

journal_title：Journal of hypertension

authors： Thomopoulos C,Parati G,Zanchetti A

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:The genes responsible for obesity are also candidate genes for obesity-related conditions, such as hypertension and type 2 diabetes. A functional polymorphism in the uncoupling protein 2 (UCP2) promoter has been reported to be associated with obesity in Caucasians. To clarify the contribution of this polymor...

journal_title：Journal of hypertension

authors： Ji Q,Ikegami H,Fujisawa T,Kawabata Y,Ono M,Nishino M,Ohishi M,Katsuya T,Rakugi H,Ogihara T

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:It is not well known which exercise intensity is needed to obtain blood pressure reductions in response to endurance training. We therefore compared the effect of training at lower and higher intensity on blood pressure, and, in addition on other cardiovascular risk factors, in at least 55-year-old sedentary ...

journal_title：Journal of hypertension

authors： Cornelissen VA,Arnout J,Holvoet P,Fagard RH

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND AIM:Ambulatory blood pressure monitoring (ABPM) is superior to conventional BP measurement in predicting outcome, with baseline 24-h, daytime and night-time absolute values, as well as relative nocturnal decline, as powerful determinants of prognosis. We aimed to evaluate ABPM estimates on the appearance...

journal_title：Journal of hypertension

authors： de la Sierra A,Banegas JR,Segura J,Gorostidi M,Ruilope LM,CARDIORISC Event Investigators.

更新日期：2012-04-01 00:00:00