Pulmonary metastasectomy in patients with renal cell carcinoma: a single-institution experience.

abstract：BACKGROUND:Some childhood cancer survivors experience employment difficulties. This study aimed to describe pediatric brain-tumor survivors' employment status. METHODS:A cross-sectional, observational study was conducted, with questionnaires distributed to 101 pediatric brain-tumor survivors (aged 15 years or older) a...

journal_title：International journal of clinical oncology

authors： Sato I,Higuchi A,Yanagisawa T,Murayama S,Kumabe T,Sugiyama K,Mukasa A,Saito N,Sawamura Y,Terasaki M,Shibui S,Takahashi J,Nishikawa R,Ishida Y,Kamibeppu K

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:UFT is composed of tegafur, a prodrug of 5-fluorouracil, and uracil, at a fixed ratio of 1: 4. UFT is widely used with leucovorin as adjuvant chemotherapy in patients with colon cancer. As reported, UFT/leucovorin should not be taken simultaneously with food because a high fat content will reduce the systemi...

journal_title：International journal of clinical oncology

authors： Furuhata T,Meguro M,Nishidate T,Okita K,Ishiyama G,Iwayama Y,Hosokawa Y,Tsuruma T,Kimura Y,Mizuguchi T,Sasaki K

更新日期：2009-12-01 00:00:00

abstract：:Brachytherapy is an important radio-therapeutic modality for a variety of malignancies, including prostate cancer, cervix cancer, breast cancer, vagina cancer, endometrium cancer, head and neck cancer, and many more. This technique has been shown to be an effective and safe non-pharmaceutical treatment with fewer seri...

journal_title：International journal of clinical oncology

authors： Deng X,Wu H,Gao F,Su Y,Li Q,Liu S,Cai J

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:We conducted a phase I dose escalation study to determine the maximum tolerated dose (MTD), the recommended dose (RD) and the safety profile of amrubicin (AMR) plus paclitaxel (PTX) combination regimen for patients with previously treated non-small cell lung cancer (NSCLC). PATIENTS AND METHODS:PTX was admi...

journal_title：International journal of clinical oncology

authors： Kaira K,Sunaga N,Imai H,Kamide Y,Koga Y,Ono A,Kuwako T,Masuda T,Hisada T,Ishizuka T,Yamada M

更新日期：2016-04-01 00:00:00

abstract：:We report the case of a 65-year-old man with recurrent prostate cancer who presented with meningeal carcinomatosis. In September 2007, he had been diagnosed with mixed type small cell carcinoma and adenocarcinoma at clinical stage T4N1M1 (primary prostate tumor with multiple bone, liver, and lymph node metastases) and...

journal_title：International journal of clinical oncology

authors： Yamada T,Ohtsubo K,Mouri H,Yamashita K,Yasumoto K,Izumi K,Zen Y,Watanabe H,Yano S

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:In this phase I/II study, we assessed the safety and initial efficacy of stereotactic body radiotherapy (SBRT) for lung tumors with real-time tumor tracking using CyberKnife based on the Monte Carlo algorithm. METHODS:Study subjects had histologically confirmed primary non-small-cell lung cancer staged as T...

journal_title：International journal of clinical oncology

authors： Iwata H,Ishikura S,Murai T,Iwabuchi M,Inoue M,Tatewaki K,Ohta S,Yokota N,Shibamoto Y

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:High-risk factors for recurrence of head and neck squamous cell carcinoma after surgical resection include involvement of ≥ 2 regional lymph nodes, extracapsular spread, and microscopic involvement of resected mucosal margins. Adjuvant chemoradiotherapy is thought to improve postoperative locoregional contro...

journal_title：International journal of clinical oncology

authors： Yokota T,Onitsuka T,Kusafuka K,Ogawa H,Onozawa Y,Nakagawa M,Iida Y,Kamijo T,Nishimura T,Nakajima T,Boku N,Yasui H

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Evaluation of the prognosis in patients with spinal metastases is important in decision making regarding surgical treatment. The purpose of this study was to investigate overall survival in patients with spinal metastases from lung cancer by histological subtype, and to investigate prognostic factors in pati...

journal_title：International journal of clinical oncology

authors： Dohzono S,Sasaoka R,Takamatsu K,Nakamura H

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:When soft-tissue sarcomas occur near neurovascular structures, preoperative images cannot always reveal the accurate relationship between the tumor and these structures. Therefore, in some patients, neurovascular structures are sacrificed unnecessarily. In other patients, neurovascular structures are preserv...

journal_title：International journal of clinical oncology

authors： Matsumoto S,Kawaguchi N,Manabe J,Matsushita Y

更新日期：2002-02-01 00:00:00

abstract：:A 45-year-old woman with HER2(-)/HER1(-) breast cancer underwent radical mastectomy, followed by radiation and chemotherapy. However, her symptoms progressed rapidly owing to meningitis carcinomatosa and she was fitted with a urethral catheter. She also had difficulty in walking. However, immediately after treatment w...

journal_title：International journal of clinical oncology

authors： Onishi H,Morisaki T,Nakafusa Y,Nakashima Y,Yokohata K,Katano M

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Increase of the Ca2+-activated chloride channel TMEM16A is contribute to tumorigenesis. However, the expression level of TMEM16A and its underlying molecular mechanism for TMEM16Apromotingliver carcinogenesis is remains unknown. METHODS:In the present study, the expression of TMEM16A in hepatocellular carci...

journal_title：International journal of clinical oncology

authors： Zhang C,Liu J,Han Z,Cui X,Peng D,Xing Y

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:This study was conducted to determine the efficacy and safety of low-dose chemotherapy with methotrexate (MTX) and vinblastine (VBL) for patients with desmoid tumors refractory to meloxicam treatment, focusing in particular on the relationship between the efficacy of this chemotherapy and catenin β-1 (CTNNB1...

journal_title：International journal of clinical oncology

authors： Nishida Y,Tsukushi S,Urakawa H,Hamada S,Kozawa E,Ikuta K,Ando Y,Ishiguro N

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that somatic mutations in the AT-rich interactive domain 1A (SWI-like) gene (ARID1A) are the most common genetic changes in clear cell carcinoma of the ovary (CCC). A gene mutation of ARID1A was found in approximately half of CCC cases, and led to absence of the encoded protein and ...

journal_title：International journal of clinical oncology

authors： Itamochi H,Oumi N,Oishi T,Shoji T,Fujiwara H,Sugiyama T,Suzuki M,Kigawa J,Harada T

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the predictive value of preoperative hydronephrosis for pathological outcome and prognosis in patients with upper tract urothelial carcinoma treated with nephroureterectomy. METHODS:167 patients with UTUC treated with nephroureterectomy at our two institutions in Japan between 2002 and 2017 were ...

journal_title：International journal of clinical oncology

authors： Fukui T,Kanno T,Kobori G,Moroi S,Yamada H

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:SmithKline Beecham synthesized camptothecin analogs and identified nogitecan hydrochloride (topotecan) with a broad spectrum of antitumor activity and less toxicity than camptothecin. Because preclinical and overseas clinical data indicated the antitumor effect of nogitecan hydrochloride with a 5-day repeat-...

journal_title：International journal of clinical oncology

authors： Kobayashi K,Hino M,Fukuoka M,Takeuchi K,Furuse K,Yoneda S,Hasegawa K,Noda K,Kinoshita H,Kimura I,Taguchi T,Kanamaru R,Horikoshi N,Niitani H

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:We evaluated the longer-term efficacy and safety of concurrent chemoradiotherapy (CCRT) incorporating high-dose-rate intracavitary brachytherapy (HDR-ICBT) with a lower cumulative radiotherapy (RT) protocol and analyzed prognostic risk factors for survival among patients with FIGO stage III-IVA squamous cell...

journal_title：International journal of clinical oncology

authors： Kudaka W,Nagai Y,Toita T,Inamine M,Asato K,Nakamoto T,Wakayama A,Ooyama T,Tokura A,Murayama S,Aoki Y

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The influence of resection of the primary lesion on the prognosis of patients with incurable stage IV colorectal cancer is unclear. METHODS:We retrospectively analyzed 158 asymptomatic patients with incurable stage IV colorectal cancer who received systemic chemotherapy in our center from 2002 to 2009, eith...

journal_title：International journal of clinical oncology

authors： Watanabe A,Yamazaki K,Kinugasa Y,Tsukamoto S,Yamaguchi T,Shiomi A,Tsushima T,Yokota T,Todaka A,Machida N,Fukutomi A,Onozawa Y,Yasui H

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Pleural effusion is one of the most common complications of lung adenocarcinoma and is diagnostically challenging. This study aimed to investigate the diagnostic performance of carcinoembryonic antigen (CEA), cytokeratin fragment (CYFRA) 21-1, and cancer antigen (CA) 19-9 for lung adenocarcinoma-associated m...

journal_title：International journal of clinical oncology

authors： Feng M,Zhu J,Liang L,Zeng N,Wu Y,Wan C,Shen Y,Wen F

更新日期：2017-04-01 00:00:00

abstract：:Recent advances in molecular biology have identified the responsible genes for many hereditary cancer syndromes (familial tumors). Therefore, now, the final diagnosis of familial tumors can be done by molecular methods to detect the genetic alteration in the disease-causing responsible gene(s) in the patient. So-calle...

journal_title：International journal of clinical oncology

authors： Tomita N,Oto M

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Pulmonary wedge resection is an option for lung cancer patients with limited cardiopulmonary preservation. As the impact of underlying lung status on the prognosis of such patients remains unclear, we assessed this issue. METHODS:A total of 149 borderline surgical candidates with localized lung cancer who h...

journal_title：International journal of clinical oncology

authors： Kawaguchi T,Sawabata N,Miura S,Kawai N,Yasukawa M,Tojo T,Taniguchi S

更新日期：2019-04-01 00:00:00

abstract：:Ovarian clear cell carcinoma (OCCC) is a histological subtype of epithelial ovarian carcinoma prevalent in Asians. No clear therapeutic selection based on molecular profile has been implemented for this disease. Oncogenic PIK3CA mutation, which activates the PIK3CA/AKT/mTOR signaling pathway, is a promising druggable ...

journal_title：International journal of clinical oncology

authors： Kuroda T,Kohno T

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:This retrospective study was carried out to ascertain the extent of efficacy of nonsurgical salvage modalities, mainly chemotherapy (CT) alone or chemoradiotherapy (CTRT), for loco-regional failures in head and neck cancer (HNC). METHODS:Between 1991 and 1999, 131 patients with HNC, mostly stages III and IV...

journal_title：International journal of clinical oncology

authors： Datta NR,Nagar YS,Singh S,Naryan L

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Based on the results of the SPIRITS trial, combination chemotherapy of S-1 plus cisplatin (SP) is now considered the standard treatment for patients with advanced gastric cancer (AGC) in Japan. On the other hand, several non-Japanese studies have shown the efficacy of capecitabine plus cisplatin (XP), which ...

journal_title：International journal of clinical oncology

authors： Shitara K,Sawaki A,Matsuo K,Kondo C,Takahari D,Ura T,Tajika M,Niwa Y,Muro K

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Although several reports have discussed the potential of the indocyanine green (ICG) fluorescence technique, its effectiveness and limitations have not been fully evaluated. For the accurate detection of sentinel lymph node (SLN) in cutaneous melanoma, which can arise in a wide variety of sites throughout th...

journal_title：International journal of clinical oncology

authors： Namikawa K,Tsutsumida A,Tanaka R,Kato J,Yamazaki N

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The combination of a new oral dihydropyrimidine dehydrogenase-inhibitory fluoropyrimidine (S-1) and cisplatin (CDDP) is one of the most active chemotherapy regimens for gastric cancer. However, the optimum schedule for this combination has not yet been determined. This study was conducted to establish the ma...

journal_title：International journal of clinical oncology

authors： Sato Y,Kondo H,Honda K,Takahari D,Sumiyoshi T,Tsuji Y,Yoshizaki N,Niitsu Y

更新日期：2005-02-01 00:00:00

abstract：:A case of mantle cell lymphoma (MCL) associated with multiple lymphomatous polyposis (MLP) is reported is a 62-year-old woman, with special reference to the patient's clinical features and response to treatment. There were multiple widespread polypoid lesions in the entire gastrointestinal tract, with ileocecal masses...

journal_title：International journal of clinical oncology

authors： Tsujimura H,Takagi T,Tamaru J,Sakai C

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:This study searched for extra capsular tumour spread (ECS) as a prognostic factor for recurrence in terms of Disease Free Survival (DFS) and Overall Survival (OS). PATIENTS AND METHODS:For this study, from a retrospective database of the Doubs cancer registry, 823 eligible women with node positive breast ca...

journal_title：International journal of clinical oncology

authors： Dobi E,Bazan F,Dufresne A,Demarchi M,Villanueva C,Chaigneau L,Montcuquet P,Ivanaj A,Sautière JL,Maisonnette-Escot Y,Cals L,Algros MP,Woronoff AS,Pivot X

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the screening rate for hepatitis B virus (HBV) infection, which is recommended by some guidelines for the prevention of HBV reactivation, in patients undergoing chemotherapy for malignancy in Japan. METHODS:The study subjects were 3302 patients who had received first...

journal_title：International journal of clinical oncology

authors： Ikeda M,Yamamoto H,Kaneko M,Oshima H,Takahashi H,Umemoto K,Watanabe K,Hashimoto Y,Ohno I,Mitsunaga S,Okusaka T

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Hypofractionated proton therapy (HFPT) is expected to become an effective treatment approach for localized prostate cancer (PCa). The purpose of this study was to evaluate differences in acute toxicity among patients with localized PCa treated with either conventional fractionated proton therapy (CFPT) or HF...

journal_title：International journal of clinical oncology

authors： Nakajima K,Iwata H,Ogino H,Hattori Y,Hashimoto S,Nakanishi M,Toshito T,Umemoto Y,Iwatsuki S,Shibamoto Y,Mizoe JE

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Neoadjuvant cisplatin-based chemotherapy for patients with muscle-invasive bladder cancer (BC) has better survival benefit than radical cystectomy (RC) alone. However, optimal dosing schedule, including drug selection, number of cycles, and interval between chemotherapy and cystectomy, as well as acceptable ...

journal_title：International journal of clinical oncology

authors： Koie T,Ohyama C,Hashimoto Y,Hatakeyama S,Yamamoto H,Yoneyama T,Kamimura N

更新日期：2013-08-01 00:00:00