F0F1-ATPase of plant mitochondria: isolation and polypeptide composition.

abstract：:The placenta releases syncytiotrophoblast-derived extracellular vesicles (STB-EV) into the maternal circulation throughout gestation. STB-EV dependent signalling is believed to contribute to the widespread maternal adaptive physiological changes seen in pregnancy. Transfer RNA (tRNA) halves have been identified in ves...

journal_title：Biochemical and biophysical research communications

authors： Cooke WR,Cribbs A,Zhang W,Kandzija N,Motta-Mejia C,Dombi E,Ri R,Cerdeira AS,Redman C,Vatish M

更新日期：2019-10-08 00:00:00

abstract：:Tubulointerstitial nephritis antigen (TIN-ag) is an extracellular matrix basement protein which was originally identified as a target antigen involved in anti-tubular basement membrane (TBM) antibody-mediated interstitial nephritis (TIN). Further investigations elucidated that TIN-ag plays a role in renal tubulogenesi...

journal_title：Biochemical and biophysical research communications

authors： Ikeda M,Takemura T,Hino S,Yoshioka K

更新日期：2000-02-05 00:00:00

abstract：:The beta-subunit of human chorionic gonadotropin (beta-hCG) is secreted by many kinds of tumors and it has been used as an ideal target antigen to develop vaccines against tumors. In view of the low immunogenicity of this self-peptide,we designed a method based on isocaudamer technique to repeat tandemly the 10-residu...

journal_title：Biochemical and biophysical research communications

authors： Yankai Z,Rong Y,Yi H,Wentao L,Rongyue C,Ming Y,Taiming L,Jingjing L,Jie W

更新日期：2006-07-14 00:00:00

abstract：:Interleukin-6 (IL-6) signal is transduced through a membrane glycoprotein gp130, which associates with the IL-6 receptor alpha chain (IL-6R alpha) in the presence of IL-6. We prepared monoclonal antibodies (mAbs) specific to murine gp130 by immunizing rats and hamsters with a chimeric molecule consisting of the extrac...

journal_title：Biochemical and biophysical research communications

authors： Matsuda T,Hirano T

更新日期：1994-07-15 00:00:00

abstract：:Hydrophobic modifications of transducin (T) gamma, such as farnesyl-and carboxyl-methylation, are essential for the association of T beta gamma with the photoreceptor disc membrane, and MEKA/phosducin is known to inhibit the association. In this study, we examined the effect of MEKA on the hydrophobicity of T beta gam...

journal_title：Biochemical and biophysical research communications

authors： Tanaka H,Kuo CH,Matsuda T,Fukada Y,Hayashi F,Ding Y,Irie Y,Miki N

更新日期：1996-06-25 00:00:00

abstract：:We previously reported synergistic induction of apoptosis by IFN-gamma plus either cyclosporin A (CsA) or tacrolimus (FK506) in gastric carcinoma cells. In this study, we aimed to elucidate the mechanism for this synergistic induction of apoptosis. IFN-gamma plus CsA synergistically induced caspase-3 mediated apoptosi...

journal_title：Biochemical and biophysical research communications

authors： Beppu K,Morisaki T,Matsunaga H,Uchiyama A,Ihara E,Hirano K,Kanaide H,Tanaka M,Katano M

更新日期：2003-06-13 00:00:00

abstract：:Factors affecting Ins(1,3,4,5)P4-mediated nuclear Ca2+ uptake are investigated, which include Ins(1,3,4,5)P4 receptor ligand specificity and free external Ca2+ concentrations. Among various inositol phosphates examined, Ins(1,3,4,5)P4, Ins(3,4,5,6)P4, and Ins(1,3,4,5,6)P5 can also stimulate 45Ca2+ influx into isolated...

journal_title：Biochemical and biophysical research communications

authors： Hsu AL,Lu PJ,Chen CS

更新日期：1998-02-24 00:00:00

abstract：:Previous studies have demonstrated an important interaction between angiotension II type 1 receptor (AT1R) and angiotension II (Ang II) -induced capillary formation from endothelial cells and vascular endothelial growth factor (VEGF). However, the underlying mechanism remains elusive. Recent studies revealed that the ...

journal_title：Biochemical and biophysical research communications

authors： Wang X,Bai YP,Hong D,Gao HC,Li LF,Li CC,Zhu LP,Sun Q,Zhang GG

更新日期：2013-05-10 00:00:00

abstract：:Five different receptor subtypes for neuropeptide Y (NPY) have recently been cloned in mammals. We have discovered three distinct subtypes by PCR in the zebrafish, Danio rerio, and describe here one of these called zYc. The protein sequence identity is 46-51% to mammalian subtypes Y1, Y4 and Y6 and to zebrafish Ya, i....

journal_title：Biochemical and biophysical research communications

authors： Ringvall M,Berglund MM,Larhammar D

更新日期：1997-12-29 00:00:00

abstract：:E3b1, a binding partner of Eps8, plays a critical role in receptor tyrosine kinase (RTK)-mediated Rac activation by facilitating the interaction of Eps8 with Sos-1 and the consequent activation of the Rac-specific guanine nucleotide exchange factor activity of Sos-1. Here we present evidence that E3b1 levels are regul...

journal_title：Biochemical and biophysical research communications

authors： Chi S,Chang S,Park D

更新日期：2004-06-25 00:00:00

abstract：:Endothelin (ET)-related peptides including ET-1 (1-39) were synthesized, and their constricting activity in rat pulmonary artery rings and pressor activity in unanesthetized rat were measured to elucidate their structure-activity relationship. The vasoconstrictor activities of ET-2, ET-3 and sarafotoxin S6b were one-h...

journal_title：Biochemical and biophysical research communications

authors： Nakajima K,Kubo S,Kumagaye S,Nishio H,Tsunemi M,Inui T,Kuroda H,Chino N,Watanabe TX,Kimura T

更新日期：1989-08-30 00:00:00

abstract：:The Rex-family repressors sense redox levels by alternative binding to NADH or NAD(+). RSP is the homologue of Rex in Thermoanaerobacter ethanolicus JW200(T) and regulates ethanol fermentation in this obligate anaerobe. The dimeric repressor binds to DNA by an open conformation. The crystal structure of RSP/α-NAD(+) c...

journal_title：Biochemical and biophysical research communications

authors： Zheng Y,Ko TP,Yang Y,Shao W,Guo RT

更新日期：2015-01-16 00:00:00

abstract：:The profile of primary dioxygenation products of arachidonic acid catalyzed by lipoxygenase isolated from hairy root cultures of Solanum tuberosum treated with a fungal elicitor was compared to that obtained for the enzyme from potato tubers. 11-Hydroperoxyeicosatetraenoic acid (11-HPETE) was the most abundant dioxyge...

journal_title：Biochemical and biophysical research communications

authors： Reddy GR,Reddanna P,Reddy CC,Curtis WR

更新日期：1992-12-30 00:00:00

abstract：:The 3' untranslated region (UTR) of the hepatitis C virus (HCV) is believed to function in the initiation and regulation of viral RNA replication and protein translation by interacting with the viral and host components. To examine host proteins interacting with the HCV 3'UTR, biotinylated 3'(+)UTR, and its reverse co...

journal_title：Biochemical and biophysical research communications

authors： Tingting P,Caiyun F,Zhigang Y,Pengyuan Y,Zhenghong Y

更新日期：2006-09-01 00:00:00

abstract：:Platelet adhesion to VLDL, LDL, HDL, and to a mixture of purified apolipoproteins was examined. Platelets adhered to all the classes of lipoproteins tested. VLDL and the apolipoprotein mixture promoted the greatest degree of adhesion. Platelet adhesion was inhibited by addition of EDTA, RGD-containing peptides and ant...

journal_title：Biochemical and biophysical research communications

authors： Kowalska MA,Tuszynski GP,Capuzzi DM

更新日期：1990-10-15 00:00:00

abstract：:The 32/20-kDa two-chain form of protective protein/cathepsin A (CathA) secreted by human platelets was thermostable in the aggregation supernatant at acidic pH, but was denatured at neutral pH. Leupeptin partly protected the CathA against denaturation, which was not observed in the supernatant after depletion of the c...

journal_title：Biochemical and biophysical research communications

authors： Itoh K,Naganawa Y,Kamei S,Shimmoto M,Sakuraba H

更新日期：1998-12-18 00:00:00

abstract：:RBM39, also known as splicing factor HCC1.4, acts as a transcriptional coactivator for the steroid nuclear receptors JUN/AP-1, ESR1/ER-α and ESR2/ER-β. RBM39 is involved in the regulation of the transcriptional responses of these steroid nuclear receptors and promotes transcriptional initiation. In this paper, we repo...

journal_title：Biochemical and biophysical research communications

authors： Mai S,Qu X,Li P,Ma Q,Liu X,Cao C

更新日期：2016-04-22 00:00:00

abstract：:Adipose tissue is an endocrine organ that produces and secretes adipokines. The aim of this study was to identify genes predominantly expressed in human subcutaneous adipocytes. For this purpose, an algorithm was developed and DNA microarray expression profiles from 33 human tissues and cell types were used to select ...

journal_title：Biochemical and biophysical research communications

authors： Sjöholm K,Palming J,Lystig TC,Jennische E,Woodruff TK,Carlsson B,Carlsson LM

更新日期：2006-06-16 00:00:00

abstract：:A two fold stimulation in the incorporation of [3H-methyl] groups from [3H-methyl] methionine into phospholipids was seen in intact pancreatic islets within six minutes of exposure to a glucose concentration that stimulates insulin release. Nonstimulatory sugars, L-glucose and D-galactose, as well as dibutyryl cAMP, d...

journal_title：Biochemical and biophysical research communications

authors： Kowluru A,Rana RS,MacDonald MJ

更新日期：1984-07-31 00:00:00

abstract：:Stimulation of leucine uptake by addition of concanavalin A, mediated by increase of intracellular free Ca2+ concentration [( Ca2+]), in lymphocytes (Mitsumoto, Y., Sato, K. and Mohri, T. (1988) Biochim. Biophys. Acta 968, 353-358) was abolished by N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) and chlorprom...

journal_title：Biochemical and biophysical research communications

authors： Sato K,Mitsumoto Y,Mohri T

更新日期：1988-06-16 00:00:00

abstract：:Glucose-dependent insulinotropic polypeptide is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions. The glucose-dependent action of GIP on pancreatic beta-cells has attracted attention towards its exploitation as a potential drug for type 2 diabetes. Use of NMR or X-ray...

journal_title：Biochemical and biophysical research communications

authors： Alaña I,Hewage CM,Malthouse JP,Parker JC,Gault VA,O'Harte FP

更新日期：2004-12-03 00:00:00

abstract：:Vasodilator-stimulated phosphoprotein (VASP) is an actin regulatory protein that functions in adhesion and migration. In epithelial cells, VASP participates in cell-cell adhesion. At the molecular level, VASP drives actin bundling and polymerization. VASP activity is primarily regulated by phosphorylation. Three physi...

journal_title：Biochemical and biophysical research communications

authors： Thomson DM,Ascione MP,Grange J,Nelson C,Hansen MD

更新日期：2011-10-14 00:00:00

abstract：:We have studied the convergence of the biosynthetic lysosomal route marked by the newly synthesized lysosomal enzyme arylsulfatase A (ASA) with the endosomal/prelysosomal compartment in ASA overexpressing baby hamster kidney (BHK) cells. A monoclonal antibody against ASA conjugated to transferrin (Tf-alpha ASA) was us...

journal_title：Biochemical and biophysical research communications

authors： Diesner F,Sommerlade HJ,Braulke T

更新日期：1993-11-30 00:00:00

abstract：:Pyruvate kinase M2 (PKM2) is a key enzyme of glycolysis which is highly expressed in many tumor cells, and plays an important role in the Warburg effect. In previous study, we found PIM2 phosphorylates PKM2 at Thr454 residue (Yu, etl 2013). However, the functions of PKM2 Thr454 modification in cancer cells still remai...

journal_title：Biochemical and biophysical research communications

authors： Yu Z,Huang L,Qiao P,Jiang A,Wang L,Yang T,Tang S,Zhang W,Ren C

更新日期：2016-05-13 00:00:00

abstract：:Studies were made on the mechanism of the effect of parathyroid hormone (PTH) on the activity of (Ca2++Mg2+)-ATPase, a membrane bound Ca2+-extrusion pump enzyme from the basolateral membranes (BLM) of canine kidney (Km for free Ca2+ = 1.3 X 10(-7) M, Vmax = 200 nmol Pi/mg/min). At 1 X 10(-7) M free Ca2+, both PTH (10(...

journal_title：Biochemical and biophysical research communications

authors： Itoh K,Morimoto S,Shiraishi T,Taniguchi K,Onishi T,Kumahara Y

更新日期：1988-01-15 00:00:00

abstract：:Using red cells as an experimental model, we previously showed that a limited degradation of certain membrane proteins by calpain (Ca2+-activated thiol protease) was a necessary prerequisite for cell fusion and that fusibility depended on the ratio of calpain to its endogenous inhibitor calpastatin. Here we show that ...

journal_title：Biochemical and biophysical research communications

authors： Barnoy S,Glasner T,Kosower NS

更新日期：1996-03-27 00:00:00

abstract：:In most animal species and many prokaryotes, methylmalonyl CoA mutase catalyzes isomerization between methylmalonyl CoA and succinyl CoA using adenosylcobalamin as a cofactor. We describe the absence of this enzyme in Aspergillus nidulans based on the absence of enzyme activity in vitro and the failure to metabolize m...

journal_title：Biochemical and biophysical research communications

authors： Ledley FD,Crane AM,Klish KT,May GS

更新日期：1991-06-28 00:00:00

abstract：:p120-Catenin is known to play important roles in cell-cell adhesion stability by binding to cadherin and morphological changes of cells by regulating small RhoGTPase activities. Although the expression and binding states of p120-catenin are thought to dynamically change due to morphological adaptation of endothelial c...

journal_title：Biochemical and biophysical research communications

authors： Sakamoto N,Segawa K,Kanzaki M,Ohashi T,Sato M

更新日期：2010-07-30 00:00:00

abstract：:Human bladder carcinoma cell line EJ-1 secreted a protein of 30 kDa as a major component. This protein was purified from the serum-free conditioned medium of EJ-1. Its N-terminal amino acid sequence was identical to that of fibroblast-derived endothelial cell growth factor (f-ECGF), but there were differences in their...

journal_title：Biochemical and biophysical research communications

authors： Akaogi K,Okabe Y,Funahashi K,Yoshitake Y,Nishikawa K,Yasumitsu H,Umeda M,Miyazaki K

更新日期：1994-02-15 00:00:00

abstract：:The levels of the anti-aging protein α-Klotho, in its soluble form (s-Klotho), are depressed in the circulation of patients with type 1 diabetes (T1D) or type 2 diabetes (T2D). Gene transfer experiments have suggested a protective role for β-cell specific expression of α-Klotho in murine models of T1D and T1D, but the...

journal_title：Biochemical and biophysical research communications

authors： Prud'homme GJ,Glinka Y,Kurt M,Liu W,Wang Q

更新日期：2020-05-07 00:00:00