Anthelmintic activities of chloroform and methanol extracts of Buchholzia coriacea Engler seed.

Abstract:

:The anthelmintic potentials of the chloroform and methanol extracts of Buchholzia coriacea Engler seed were investigated. In folklore medicine, B. coriacea (Capparidaceae) is believed to be useful in the treatment of various kinds of ailments and diseases. At doses of 10 mg/kg, 25 mg/kg and 50 mg/kg, the extracts were tested against Eudrilus eugeniae (earthworm) and Bunostomum phlebotomum (cattle hookworm). The extracts exhibited dose-dependent anthelmintic effects on the earthworms and hookworms. The methanol extract at 50 mg/kg was the most active extract against the helminths, and the activity of the methanol extract was not significantly different from that of piperazine hydrate (reference drug, 10 mg/kg) against the earthworms.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

Fred-Jaiyesimi AA,Adepoju A,Egbebunmi O

doi

10.1007/s00436-011-2274-y

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

441-4

issue

2

eissn

0932-0113

issn

1432-1955

journal_volume

109

pub_type

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