Abstract:
:The anti-plasmodial activity of different solvent extracts of Adhatoda vasica (root), Caesalpinia pulcherrima (leaf), Carica papaya (pulp), Erythroxylum monogynum (leaf), Lantana camara (whole plant), Ocimum sanctum (root) and Phyllanthus niruri (whole plant) were studied against Plasmodium falciparum. Of the 35 extracts tested, seven extracts showed good anti-plasmodial activity. Methanol extract of C. pulcherrima showed the lowest IC50 value (10.96 μg/mL) followed by methanol extract of A. vasica (IC(50)=11.1 μg/mL), chloroform extract of O. sanctum (IC(50)=11.47 μg/mL), methanol extract of E. monogynum (IC(50)=12.23 μg/mL), acetone extract of C. pulcherrima (IC(50)=12.49 μg/mL), methanol extract of O. sanctum and acetone extract of A. vasica (IC(50)=14.04 μg/mL). The results of the present study justify the use of these medicinal plants in traditional practice, and also, a further study on the isolation of anti-plasmodial molecules from their active crude extracts is in progress.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Venkatesalu V,Gopalan N,Pillai CR,Singh V,Chandrasekaran M,Senthilkumar A,Chandramouli Ndoi
10.1007/s00436-012-2834-9subject
Has Abstractpub_date
2012-07-01 00:00:00pages
497-501issue
1eissn
0932-0113issn
1432-1955journal_volume
111pub_type
杂志文章abstract::Numerous species of Sarcocystis have been reported from wild ruminants, but none has been named from the Rocky Mountain goat (Oreamnos americanus). Mature sarcocysts were found in frozen muscle samples of three of seven mountain goats from Alaska, USA. Two morphological types of sarcocysts were found; one had Sarcocys...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-015-4644-3
更新日期:2015-11-01 00:00:00
abstract::We have identified the 2-Cys peroxiredoxin (Prx) from a bovine Babesia parasite, B. bovis. Prx is a recently described family of antioxidant enzymes that are highly conserved in eukaryotes and prokaryotes. B. bovis 2-Cys Prx (BbTPx-1) contained two conserved cysteine residues that corresponded to Cys47 and Cys170 of t...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-009-1587-6
更新日期:2009-10-01 00:00:00
abstract::Toxoplasma gondii, the agent of toxoplasmosis, is an intracellular parasite that can infect a wide range of vertebrate hosts. Toxoplasmosis causes severe damage to immunocompromised hosts and its treatment is mainly based on the combination of pyrimethamine and sulfadiazine, which causes relevant side effects primaril...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-019-06493-6
更新日期:2019-12-01 00:00:00
abstract::According to the genetic characterization by the analysis of the miniexon gene, strains of Trypanosoma cruzi can be classified into six discrete typing units (DTUs), and the DTU 1 into four distinct genotypes associated with different life cycles. While Chagas disease is endemic in Costa Rica, T. cruzi isolates from t...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-012-3000-0
更新日期:2012-10-01 00:00:00
abstract::With climate warming, malaria in humans and birds at upper elevations is an emerging infectious disease because development of the parasite in the mosquito vector and vector life history are both temperature dependent. An enhanced-mosquito-movement model from climate warming predicts increased transmission of malaria ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3578-x
更新日期:2013-11-01 00:00:00
abstract::The C57BL/6J strain of Mus musculus is susceptible to the terrestrial trematode Brachylaima cribbi. The duration of infection in these mice is generally 9-12 weeks with a peak excretion of eggs at 4 weeks post-infection (wpi). The effects of age and sex on the course of infection were investigated by comparing infecti...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-002-0642-3
更新日期:2002-07-01 00:00:00
abstract::Murine immunological responses to experimental infection with Trichuris muris and the effects of the resident microbiota on these responses are of increasing interest. For these studies, accurate dose delivery and improved sterilization of inocula are essential to prevent co-infection with unknown contaminants. We fou...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-010-1978-8
更新日期:2010-10-01 00:00:00
abstract::Two hundred forty feral domestic cats trapped between 2004 and 2008 in the city centre and the suburb districts of Dubai, as well as in desert biotopes, were subjected to a complete parasitological dissection. The established parasite fauna consisted of Cystoisospora felis (12.9%), Cystoisospora rivolta (9.2%), Toxopl...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-009-1372-6
更新日期:2009-07-01 00:00:00
abstract::Benzimidazole anthelmintics are widely used against nematode, cestode and trematode parasites. The drugs undergo several enzyme-mediated reactions within the host animal that produce a number of metabolites. Although it has been shown that certain helminths, including Fasciola hepatica, can metabolise albendazole, not...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-003-1003-6
更新日期:2004-02-01 00:00:00
abstract::Physaloptera rara (Spirurida: Physalopteridae) has been found in dogs, coyotes, raccoons, wolves, foxes, cats, and bobcats in North America. The parasites' developmental cycles involve insects, including beetles, cockroaches, and crickets, as intermediate hosts. The nematodes firmly attach to the wall of the stomach a...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3356-9
更新日期:2013-05-01 00:00:00
abstract::Infection with helminth parasites or the administration of their antigens can prevent or attenuate autoimmune diseases. To date, the specific molecules that prime the amelioration are only limited. In this study, recombinant Schistosoma japonicum cystatin (rSjcystatin) and fructose-1,6-bisphosphate aldolase (rSjFBPA) ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-019-06511-7
更新日期:2020-01-01 00:00:00
abstract::Parasites from Flensburg fjord, northern German Baltic coast, were investigated under regard of the component, guild, and supra community level. At least, 28 host species of the guilds snails, planktonic and benthic crustaceans, and fish (exclusively small-sized species) were infected by 53 parasite species (28 autoge...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-008-1218-7
更新日期:2009-01-01 00:00:00
abstract::Sheep infected with the triclabendazole-susceptible Cullompton isolate of Fasciola hepatica were dosed with 15 mg/kg of compound alpha at 12 weeks post-infection. Adult flukes were recovered from the bile ducts at 24, 48, and 72 h post-treatment (p.t.). Changes to the spermatogenic cells in the testis were examined by...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-009-1649-9
更新日期:2010-01-01 00:00:00
abstract::Following infection of rats with Angiostrongylus cantonensis, occurrence of anti-parasite antibody in the serum was determined with special reference to the antigens recognized by host IgG antibodies, using SDS-PAGE combined with an immunoblotting technique. Three saline extracts of digestive organ, reproductive organ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00531092
更新日期:1987-01-01 00:00:00
abstract::NADH-ubiquinone oxidoreductase activity is present in mitochondrial lysates of Phytomonas serpens. Rotenone at 2-10 microM inhibited the activity 50-75%, indicating that it belongs to respiratory complex I. The activity was also inhibited 50-60% in the presence of 10-30 nM atovaquone suggesting that inhibition of comp...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-003-1058-4
更新日期:2004-03-01 00:00:00
abstract::The sequence, genomic organization, and transcription of the gene encoding the H2A histone protein of the protozoan parasite Trypanosoma rangeli is described in this paper. The locus encoding the T. rangeli H2A protein is formed by at least 11 gene units measuring 790 nucleotides in length, organized in tandem, and lo...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s004360000270
更新日期:2000-11-01 00:00:00
abstract::The protozoan parasite Giardia duodenalis is known to infect humans and a wide range of animals globally. However, no studies on G. duodenalis infection in Bactrian camels have been reported. In the present study, in order to examine the prevalence and genetic diversity of G. duodenalis in Bactrian camels, 852 fecal s...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-020-06905-y
更新日期:2020-11-01 00:00:00
abstract::Spermiogenesis of the monozoic cestode Caryophyllaeus laticeps (Pallas, 1781) (Caryophyllidea: Caryophyllaeidae), a parasite of Abramis brama (Pisces: Cyprinidae), has been investigated by means of transmission electron microscopy and cytochemical staining with periodic acid-thiosemicarbazide-silver proteinate for gly...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-011-2463-8
更新日期:2012-01-01 00:00:00
abstract::The Culicinomyces clavisporus is a fungal pathogen of a wide range of mosquito larvae. The C. clavisporus was isolated from the larvae of Culiseta inornata. We have investigated into potential pathogenicity against the adults of Culex quinquefasciatus, Aedes aegypti and Anopheles stephensi. The culture filtrates relea...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-011-2482-5
更新日期:2012-01-01 00:00:00
abstract::Exposure to viable Acanthamoeba may cause fatal encephalitis and blinding keratitis in humans. Quantification of environmental Acanthamoeba by a reliable analytical assay is essential to assess the risk of human exposure and efficacy of control measures (e.g., superheating). Two DNA binding dyes (ethidium monoazide (E...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3556-3
更新日期:2013-11-01 00:00:00
abstract::Analysis of the influence of horse-keeping conditions by contamination of the environment (pastures, paddocks, and stalls) by the strongylid infective larvae (L(3)) was carried out at various types of horse farms, hippodromes, and riding clubs in Ukraine. A total of 1,237 horses from three types of horse-keeping condi...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-011-2684-x
更新日期:2012-05-01 00:00:00
abstract::The var-gene encoding Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is known to play a major role in the pathogenicity of the P. falciparum parasite. The protein enables the parasite to adhere to the endothelial linings of small blood vessels (cytoadherence) as well as to non-infected erythrocytes (ros...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-009-1583-x
更新日期:2009-11-01 00:00:00
abstract::Canine demodicosis is a severe and highly prevalent dermatologic disease in dogs. Pet dogs can be affected by three recognized Demodex species that can produce clinical effects. In this paper, three morphological types of Demodex mites have been isolated from Spanish dogs. A complete morphobiometrical study of each on...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-012-3067-7
更新日期:2012-11-01 00:00:00
abstract::Cystic echinococcosis is a worldwide zoonosis caused by Echinococcus granulosus. Because the methods of diagnosis and treatment for cystic echinococcosis were limited, it is still necessary to screen target proteins for the development of new anti-hydatidosis vaccine. In this study, the triosephosphate isomerase gene ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-016-5166-3
更新日期:2016-10-01 00:00:00
abstract::Entamoeba histolytica infection in humans is still one of the leading causes of parasitic diseases among the developing countries, including India. It therefore becomes extremely important to characterize this parasite with the aim of preventing and controlling the amoebiasis which it causes. The present study describ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s004360000363
更新日期:2002-02-01 00:00:00
abstract::In this study, we screened field-caught mosquitoes for presence of Dirofilaria spp. by using a polymerase chain reaction (PCR) assay. Potential occurrence of Dirofilaria repens and Dirofilaria immitis microfilariae was examined in 3,600 mosquitoes of eight species (Aedes vexans, Aedes cinereus, Aedes rossicus, Culex p...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3526-9
更新日期:2013-10-01 00:00:00
abstract::The effect on the tegument of adult Fasciola hepatica of incubation in the sodium ionophore monensin, the Na+/K+-ATPase inhibitor ouabain and ouabain pretreatment followed by monensin has been determined in vitro by scanning and transmission electron microscopy (SEM, TEM). With monensin incubation alone (1 x 10(-6) M)...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931280
更新日期:1989-01-01 00:00:00
abstract::Trypanosoma cruzi proteinases are very likely involved in host-cell invasion. Physiological plasma-proteinase inhibitors from the macroglobulin (MG) family, among them alpha-2-macroglobulin (A2M), are found in tissues and in the plasma of mammals. By complexing to all classes of proteinases, MGs inhibit their action o...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931729
更新日期:1992-01-01 00:00:00
abstract::The uptake of amino acids is mediated by active transporters located on the basolateral and brush border membranes of intestinal epithelial cells. The current study investigated the expression of amino acid transporters (AAT) and other genes in the intestine of chicks infected with Eimeria maxima. At 7-day postinfecti...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-014-4114-3
更新日期:2014-10-01 00:00:00
abstract::In 2001, an international surveillance initiative was established, utilising a validated larval development inhibition assay to track the susceptibility of cat flea isolates to imidacloprid. In 2009, an Australian node was incorporated into the programme, joining laboratories in the United States and Europe. Field iso...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3280-z
更新日期:2013-08-01 00:00:00