Abstract:
:Innovative fermentation processes are necessary for the cost-effective production of bulk chemicals from renewable resources. Current microbial processes are either anaerobic processes, with high yield and productivity, or less-efficient aerobic processes. Oxygen utilization plays an important role in energy generation and redox metabolism that is necessary for product formation. The aerobic productivity, however, is relatively low because of rate-limiting volumetric oxygen transfer; whereas the product yield in the presence of oxygen is generally low because part of the substrate is completely oxidized to CO₂. Hence, new microbial conversion processes for the production of bulk chemicals should be anaerobic. In this opinion article, we describe different scenarios for the development of highly efficient microbial conversion processes for the anaerobic production of bulk chemicals.
journal_name
Trends Biotechnoljournal_title
Trends in biotechnologyauthors
Weusthuis RA,Lamot I,van der Oost J,Sanders JPdoi
10.1016/j.tibtech.2010.12.007subject
Has Abstractpub_date
2011-04-01 00:00:00pages
153-8issue
4eissn
0167-7799issn
1879-3096pii
S0167-7799(10)00218-0journal_volume
29pub_type
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