Abstract：
:Bone resorption and formation in terms of milligram of calcium deposited into and released from whole humerus of 15-23 weeks old male rats were assessed, via linear least-squares regression analysis of change in calcium content and 3H-tetracycline kinetics of the bone. The rate of resorption was 0.376 mg calcium per day, while formation was 0.758 mg calcium per day. The data indicate that the computation results in a simultaneous and explicit measurement of bone resorption and formation at the organ level.
journal_name
Calcif Tissue Intjournal_title
Calcified tissue internationalauthors
Li XQ,Klein Ldoi
10.1007/BF02555009subject
Has Abstractpub_date
1990-04-01 00:00:00pages
282-3issue
4eissn
0171-967Xissn
1432-0827journal_volume
46pub_type
杂志文章abstract：:Osteoporosis is a common age-related disease with a strong genetic influence. COLIA1 is one of the most extensively studied candidate genes and has consistently been associated with BMD and fracture. We examined the effects of the polymorphisms -1997G>T, -1663indelT, and +1245G>T and their haplotypes on vertebral frac...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-008-9199-1
更新日期：2009-02-01 00:00:00
abstract：:Vit-D-Dependent calcium binding protein and parvalbumin have both been detected in ameloblasts and calcified cartilage by immunohistochemical techniques. These two Ca2+ binding proteins may play a crucial role in the local accumulation of Ca2+ ions during the process of mineralization. The mechanisms underlying the de...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02405306
更新日期：1984-01-01 00:00:00
abstract：:In 11 postmenopausal women with histologically proven osteoporosis and normal lactose tolerance, a direct correlation between calcium absorption and intestinal lactase activity was observed. The results suggest that varying degrees of relative deficiencies in intestinal lactase might contribute to the graded decrease ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02557688
更新日期：1985-01-01 00:00:00
abstract：:Quantitative computed tomography (QCT) was compared to dual X-ray absorptiometry (DXA) measured in the lumbar spine of 508 European women defined as normal without fracture (NoF), or osteoporotic (OP), with either vertebral fracture (VF), or peripheral fracture (PF). The correlations between QCT and DXA BMD measuremen...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02678144
更新日期：2001-02-01 00:00:00
abstract：:Enhanced osteoclast formation and function is a fundamental cause of alterations to bone structure and plays an important role in several diseases impairing bone quality. Recent work revealed that TRP calcium channels 3 and 6 might play a special role in this context. By analyzing the bone phenotype of TRPC6-deficient...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-020-00673-8
更新日期：2020-06-01 00:00:00
abstract：:Thyroparathyroidectomized rats fed a diet containing 1.2% calcium, 0.55% phosphorus maintain normal serum levels of these ions. Treatment of such rats with parathyroid extract (PTE; 20 U/100 g twice daily; 10 days) has no statistically significant effect on rates of bone formation, matrix apposition, or osteoid matura...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02408051
更新日期：1979-11-01 00:00:00
abstract：:The aim of this study was to investigate the effect of transplanted chondrocytes on endochondral bone formation in cartilage repair tissue. In the knee joint of miniature pigs, cartilage lesions were treated by microfracturing and were then either left empty, covered with a collagen membrane, or treated by matrix-asso...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-009-9288-9
更新日期：2009-11-01 00:00:00
abstract：:Previous studies have indicated that children with inflammatory bowel disease (IBD) may not achieve optimal bone mass. We evaluated the skeletal characteristics in children and adolescents with IBD. This cross-sectional cohort study comprised 80 IBD patients (median age 14.9 years, range 5-20) with a median disease du...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-012-9617-2
更新日期：2012-08-01 00:00:00
abstract：:We investigated whether polymorphisms in PTHR1 are associated with bone mineral density (BMD), to determine whether the association of this gene with BMD was due to effects on attainment of peak bone mass or effects on subsequent bone loss. The PTHR1 gene, including its 14 exons, their exon-intron boundaries, and 1,50...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-007-9072-7
更新日期：2007-10-01 00:00:00
abstract：:The effect of long-chain n-3 polyunsaturated fatty acid (PUFA) on bone measurements was evaluated in gonad-intact middle-aged male rats. Seven rats were killed on day 0 of dietary intervention to determine bone parameters at baseline. Experimental rats (7/group) were fed one of the following lipid treatments (g/kg die...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-007-9010-8
更新日期：2007-04-01 00:00:00
abstract：:Radioiodination of synthetic human 37-49 osteocalcin requires optimal labeling conditions in order to obtain a maximum of mono- and di-iodinated tracer with little contamination by tri- and tetra-iodinated products or "radio-damage." The antibody raised against osteocalcin(h37-49) had the highest affinity for the C-te...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02555196
更新日期：1986-11-01 00:00:00
abstract：:Bone tissue is a source of growth factors; among them, insulinlike growth factor I (IGF-I) is probably an important local regulator of bone formation. This study has been carried out in order to assess the effects of natural menopause on plasma concentrations of IGF-I in the first 6 years after the cessation of gonada...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF01352006
更新日期：1993-07-01 00:00:00
abstract：:The extracellular protein matrix of developing enamel includes a major class of proteins, the amelogenins, which are believed to be concerned in regulating enamel biomineralization. Previous studies have shown the amelogenins of the extracellular matrix to be a complex of proline-rich hydrophobic proteins which, it is...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02556044
更新日期：1989-10-01 00:00:00
abstract：:The purpose of this study was to determine whether total serum calcium, parathyroid gland structure, and/or levels of parathyroid hormone, 1,25 and 24,25 DHCC, are altered in pigs with dental and skeletal fluorosis. Eight experimental animals receiving 2 mg F-/kg b.w. per day from age 8-14 months were compared with ei...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02556714
更新日期：1986-04-01 00:00:00
abstract：:Cross-sectional and case-control studies are efficient and inexpensive approaches to the study of osteoporosis; their validity depends primarily on how the subjects are sampled. Retrospective studies of fractures may be biased if measurements change as a result of the fracture. Prospective cohort studies are less pron...
journal_title：Calcified tissue international
pub_type： 杂志文章,评审
doi：10.1007/BF02555081
更新日期：1991-01-01 00:00:00
abstract：:The small leucine-rich bone proteoglycans, biglycan and decorin, can be purified by chromatography on hydroxyapatite columns, demonstrating their potential affinities for bone apatite. To determine their effects on in vitro apatite formation and growth, a mixture of the chondroitin-sulfate (CS) bone proteoglycans, or ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900339
更新日期：1997-10-01 00:00:00
abstract：:In several studies on patients with rheumatoid arthritis, an association of bone loss with a persistently high disease activity has been found. The aim of our study was to investigate the relation between disease activity and serum levels of vitamin D metabolites, parathyroid hormone (PTH), and parameters of bone turn...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900416
更新日期：1998-03-01 00:00:00
abstract：:A number of osteoporotic patients under bisphosphonate treatment present persistent fragility fractures and bone loss despite good compliance. The objective of this 18-month prospective study was to investigate the effect of teriparatide [rhPTH(1-34)] in 25 female osteoporotics who were inadequate responders to oral b...
journal_title：Calcified tissue international
pub_type： 临床试验,杂志文章
doi：10.1007/s00223-011-9500-6
更新日期：2011-08-01 00:00:00
abstract：:We compared indices of three-dimensional microstructure of iliac trabecular bone between 26 patients with vertebral compression fractures due to postmenopausal osteoporosis and 24 control subjects without vertebral fracture, who were matched for age, sex, race, menopausal status, and several densitometric and histolog...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02554913
更新日期：1985-12-01 00:00:00
abstract：:Changes in the acidity of osteoclasts were evaluated by direct measurement of the fluorescent intensity of osteoclasts exposed to acridine orange, a fluorescent weak base which becomes concentrated in acid-containing subcellular compartments. Parathyroid hormone (PTH) produced dose-dependent increases in fluorescent i...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02554924
更新日期：1985-12-01 00:00:00
abstract：:Bone and mineral metabolism has been reported to affect the development of the ossification of the posterior longitudinal ligament (OPLL). The aim of this study was to compare bone mineral densities (BMD) and rate of osteoporosis between cervical OPLL and a matched control group. We also investigated the correlation o...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-012-9662-x
更新日期：2013-01-01 00:00:00
abstract：:A whole-body counter was used to measure the retention and distribution of radioactivity along the longitudinal axis of the body during 10 days after the intravenous injection of 50 microCi of 47Ca. These data and the simultaneous measurements of the serum specific activity allowed us to calculate, by the Bauer-Carlss...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02405001
更新日期：1983-01-01 00:00:00
abstract：:Vitamin D supplements are often recommended to restore sufficiency, although the adherence to treatment is low. This study assessed vitamin D status at different time intervals following the cessation of treatment. The database of Clalit-Health-Services (CHS), a not-for-profit HMO covering more than half of the Israel...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-011-9536-7
更新日期：2011-11-01 00:00:00
abstract：:It has recently been demonstrated that calcium ionophore A23187 mimics certain of the effects of parathyroid hormone (PTH) on bone in vitro, including stimulation of 45Ca release and cAMP formation. To further examine the relative effects of these two agents on bone cell metabolism, we compared the effects of syntheti...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02411291
更新日期：1982-09-01 00:00:00
abstract：:MicroRNAs (miRNAs/miRs) are important biomarkers for the progression of intervertebral disc degeneration (IDD). We investigated the role of miR-30d in IDD progression through its interactions with forkhead box O3 (FOXO3) and C-X-C motif ligand 10 (CXCL10). We first measured the expression of miR-30d, FOXO3, and CXCL10...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-020-00760-w
更新日期：2021-02-01 00:00:00
abstract：:At 4 and 24 hours after injection of (35S)sulfate, there were 22-67% fewer silver grains on conventionally fixed sections than on sections fixed by cryotechniques. Differences were smaller when (3H) glucosamine was chosen as precursor. The number of silver grains increased between 4 and 24 hours in predentine and in a...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/BF02557834
更新日期：1985-09-01 00:00:00
abstract：:Biochemical markers applicable to the ovariectomized rat model can provide important tools for studying the bone remodeling process in this animal model of postmenopausal osteoporosis. We describe the development and application of two biochemical markers, a C-telopeptide (of type-I collagen) enzyme-linked immunosorbe...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002230010088
更新日期：2000-06-01 00:00:00
abstract：:The bone anabolic effect of parathyroid hormone (PTH) therapy is blunted when used in patients who were previously on bisphosphonate treatment. Osteocytes may play a role in the bisphosphonate silencing effect on PTH therapy since bisphosphonates have been shown to reach the lacunocanalicular system. In vivo osteocyte...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-013-9720-z
更新日期：2013-06-01 00:00:00
abstract：:To study the risk of fractures associated with anxiolytics, sedatives, and hypnotics, we conducted a case-control study. Cases were all subjects with any fracture during the year 2000 (n = 124,655). For each case, three controls (n = 373,962) matched on age and gender were randomly drawn from the background population...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s00223-007-9095-0
更新日期：2008-01-01 00:00:00
abstract：:A 56 year-old man with a 2-year history of transitional-cell carcinoma of the urinary bladder presented with back pain and diffuse radiological osteosclerosis. Laboratory studies revealed borderline-low ionized serum calcium, and markedly elevated serum alkaline phosphatase (ALP) activity and serum osteocalcin. Serum ...
journal_title：Calcified tissue international
pub_type： 杂志文章
doi：10.1007/s002239900560
更新日期：1998-12-01 00:00:00
