Effects of aminoguanidine and vitamin C on collagen type IV in diabetic nephropathy rats.

abstract：:The treatment of acromegaly is based on surgery, drugs, and radiotherapy as a third-line option. Fractionated stereotactic radiotherapy (FSRT) is a new technique with a need for long-term evaluation. The purpose of the study was to evaluate long-term results of FSRT in acromegaly. Overall, 34 patients [sex ratio 1.12,...

journal_title：Endocrine

authors： Diallo AM,Colin P,Litre CF,Diallo MM,Decoudier B,Bertoin F,Higel B,Patey M,Rousseaux P,Delemer B

更新日期：2015-12-01 00:00:00

abstract：:Inflammation is associated with several tumor development and progression. However, these associations are not clear in well-differentiated thyroid carcinomas. We assessed whether NLR is a useful prognostic marker in patients with papillary thyroid carcinomas (PTC). The medical records of all patients who underwent th...

journal_title：Endocrine

authors： Kim JY,Park T,Jeong SH,Jeong CY,Ju YT,Lee YJ,Hong SC,Ha WS,Choi SK,Jung EJ

更新日期：2014-08-01 00:00:00

abstract：:Prolactinomas are the most common secretory pituitary tumors; however, their pathogenesis is unclear. In order to explore the pathogenesis of prolactinomas, we used fiber-optic BeadArray to examine gene expression profiles in five prolactinomas compared with three normal pituitaries. Three down-regulated genes and one...

journal_title：Endocrine

authors： Jiang Z,Gui S,Zhang Y

更新日期：2010-12-01 00:00:00

abstract：:To further understand the role of ovarian hormones in the function of the serotonin neural system, we investigated the effects of estradiol (E), progesterone (P), and raloxifene on 5HT 1A and 2C receptor protein expression in the dorsal raphe region using Western blot analysis. Adult rhesus macaques (Macaca mulatta) w...

journal_title：Endocrine

authors： Henderson JA,Bethea CL

更新日期：2008-06-01 00:00:00

abstract：:Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. It is characterized by a progressive loss of dopamine in the substantia nigra and striatum. However, over 70% of dopaminergic neuronal death occurs before the first symptoms appear, which makes either early diagnos...

journal_title：Endocrine

authors： Mayo JC,Sainz RM,Tan DX,Antolín I,Rodríguez C,Reiter RJ

更新日期：2005-07-01 00:00:00

abstract：:Central circuits known to regulate food intake and energy expenditure also affect central cardiovascular regulation. For example, both the melanocortin and neuropeptide Y (NPY) peptide families, known to regulate food intake, also produce central hypertensive effects. Members of both families share a similar C-termina...

journal_title：Endocrine

authors： Gruber KA,Fan W,Akerberg H,Larhammar D,Chee MJ,Colmers WF,Cone RD

更新日期：2009-06-01 00:00:00

abstract：:In all mammalian species, the 20 amino acids of the genetic code are required for net protein accretion. The nutritional supply of amino acids for growth is defined as the net umbilical uptake of amino acids, representing the net transfer from maternal circulation, through the placenta and then to the fetus, of essent...

journal_title：Endocrine

authors： Regnault TR,de Vrijer B,Battaglia FC

更新日期：2002-10-01 00:00:00

abstract：:Increasing evidence suggests that inflammatory response may be a critical component of different brain pathologies. However, the role played by this reaction is not fully understood. The present findings suggest that neuroinflammtory mediators such as cytokines may be involved in a number of key steps in the pathologi...

journal_title：Endocrine

authors： Członkowska A,Ciesielska A,Gromadzka G,Kurkowska-Jastrzebska I

更新日期：2006-04-01 00:00:00

abstract：INTRODUCTION AND AIM:Hyperprolactinaemia in pregnancy leads to mild and reversible changes in the maternal skeletal system, and medicamentous hyperprolactinemia causes more detrimental effects. We conducted an experimental study to evaluate differences between Prlr gene expression in the duodenum, vertebrae and kidneys...

journal_title：Endocrine

authors： Radojkovic D,Pesic M,Radojkovic M,Dimic D,Vukelic Nikolic M,Jevtovic Stoimenov T,Radenkovic S,Velojic Golubovic M,Radjenovic Petkovic T,Antic S

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Pseudoacromegaly describes conditions with an acromegaly related physical appearance without abnormalities in the growth hormone (GH) axis. Acromegaloid facies, together with hypertrichosis, are typical manifestations of Cantú syndrome. CASE DESCRIPTION:We present a three-generation family with 5 affected memb...

journal_title：Endocrine

authors： Marques P,Spencer R,Morrison PJ,Carr IM,Dang MN,Bonthron DT,Hunter S,Korbonits M

更新日期：2018-03-01 00:00:00

abstract：:Quality of life (QoL) is an important aspect that reflects the way people feel and function. The assessment of QoL quality of life is an essential tool for estimating the efficacy of any therapy in different pathophysiological conditions. In normal, healthy women, the perception of QoL can be significantly modified du...

journal_title：Endocrine

authors： Gambacciani M

更新日期：2004-08-01 00:00:00

abstract：:A cohort of nine patients, mostly young adults, presented with a new sign/symptom of pheochromocytoma/paraganglioma: exercise-induced nausea and vomiting. The aims of this article are to introduce this sign/symptom and offer a possible hypothesis for the observation. Following a 2000 report from a paraganglioma patien...

journal_title：Endocrine

authors： King KS,Darmani NA,Hughes MS,Adams KT,Pacak K

更新日期：2010-06-01 00:00:00

abstract：:Urocortin 3 (Ucn3) is recognized as a member of the corticotropin-releasing factor (CRF) family, which plays an important role in regulating food intake. We investigated the effects of centrally administered Ucn3 on food intake and gastric emptying in mice. Intracerebroventricular (ICV)administration of Ucn3 (0.1–1 nm...

journal_title：Endocrine

authors： Ushikai M,Asakawa A,Sakoguchi T,Tanaka C,Inui A

更新日期：2011-04-01 00:00:00

abstract：:Taking metformin with a meal has been shown to decrease bioavailability of metformin. We hypothesized that taking metformin 30 min before a meal improves glucose metabolism. As an animal model, 18 Zucker-rats were divided into three groups as follows: no medication (Control), metformin (600 mg/kg) with meal (Met), and...

journal_title：Endocrine

authors： Hashimoto Y,Tanaka M,Okada H,Mistuhashi K,Kimura T,Kitagawa N,Fukuda T,Majima S,Fukuda Y,Tanaka Y,Yamada S,Senmaru T,Hamaguchi M,Asano M,Yamazaki M,Oda Y,Hasegawa G,Nakamura N,Fukui M

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:Octreotide (OCT) has been successfully used for treatment of acromegaly and neuroendocrine tumors for more than 30 years. However, long-term safety of OCT has not been documented in placebo-controlled setting. This present analysis pooled safety data from two similarly-designed, randomized, and placebo-controll...

journal_title：Endocrine

authors： Pivonello R,Muscogiuri G,Holder G,Paul M,Sarp S,Lesogor A,Jordaan P,Eisinger J,Colao A

更新日期：2018-04-01 00:00:00

abstract：:Acromegaly is a debilitating disease usually caused by a growth-hormone secreting pituitary adenoma. Therapeutic goals include improvement of symptoms, reduction in tumor mass, biochemical normalization, and preservation of pituitary function. Treatment options include transsphenoidal surgery, radiation, and pharmacot...

journal_title：Endocrine

authors： Danoff A,Kleinberg D

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:Hormonal status and menopause affect human macrophage function and cardiometabolic risk. In polycystic ovary syndrome (PCOS) patients the cardiometabolic risk increases through mechanisms that are largely unknown. We tested the hypotheses that macrophage activation is influenced by menstrual cycle and that ovar...

journal_title：Endocrine

authors： Tedesco S,Adorni MP,Ronda N,Cappellari R,Mioni R,Barbot M,Pinelli S,Plebani M,Bolego C,Scaroni C,Bernini F,Fadini GP,Cignarella A

更新日期：2019-11-01 00:00:00

abstract：:We validated the effect of prolactin-releasing peptide (PrRP) on prolactin (PRL) secretion from rat anterior pituitary cells in in vitro culture. We found that culture conditions considerably influenced the response of the anterior pituitary cells to PrRP. Longer culture term (4 d) was required to obtain better respon...

journal_title：Endocrine

authors： Kawamata Y,Fujii R,Fukusumi S,Habata Y,Hosoya M,Hinuma S,Kitada C,Onda H,Nishimura O,Fujino M

更新日期：2000-06-01 00:00:00

abstract：PURPOSE:The study aimed to disclose mortality pattern and quantitatively evaluate risks for cause-specific mortality among thyroid cancer survivors. METHODS:We included 173,710 patients from the Surveillance, Epidemiology, and End Results (SEER) database with thyroid cancer diagnosed between 1975 and 2015. Standardize...

journal_title：Endocrine

authors： Du B,Wang F,Wu L,Wang Z,Zhang D,Huang Z,Gao L,Li Y,Liang C,Li P,Yao R

更新日期：2020-08-08 00:00:00

abstract：:Both osteoporosis and cardiovascular disease (CVD) are major public health problems leading to increased morbidity and mortality. Although traditionally viewed as separate disease entities that increase in prevalence with aging, accumulating evidence indicates that there are similar pathophysiological mechanisms under...

journal_title：Endocrine

authors： McFarlane SI,Muniyappa R,Shin JJ,Bahtiyar G,Sowers JR

更新日期：2004-02-01 00:00:00

abstract：:MicroRNAs (miRNAs) have been identified to play important functions during osteoblast proliferation, differentiation, and apoptosis. The miR-17~92 cluster is highly conserved in all vertebrates. Loss-of-function of the miR-17-92 cluster results in smaller embryos and immediate postnatal death of all animals. Germline ...

journal_title：Endocrine

authors： Zhou M,Ma J,Chen S,Chen X,Yu X

更新日期：2014-03-01 00:00:00

abstract：:Fibromyalgia (FM) is a disease entity consisting of a heterogeneous cluster of symptoms that has thus far eluded identification of a causative etiology. The disease onset appears to follow physiological and/or psychological stressors and involves a subset of symptoms that are consistent with varied disorders found in ...

journal_title：Endocrine

authors： Shuer ML

更新日期：2003-10-01 00:00:00

abstract：:The effects of endomorphin-1 (EM1) on behavioral responses and on the hypothalamic-pituitary-adrenal system were investigated in mice. Locomotor activity was measured in an "open-field" apparatus, with parallel recording of the numbers of rearings and groomings. Different doses of the peptide (250 ng to 5 microg) were...

journal_title：Endocrine

authors： Bujdosó E,Jászberényi M,Tömböly C,Tóth G,Telegdy G

更新日期：2001-03-01 00:00:00

abstract：:Follicle-stimulating hormone (FSH) is a key stimulant for the development of the ovarian follicle, while luteinizing hormone (LH) plays a major role in triggering ovulation and luteinization. Both FSH and LH are glycoprotein hormones that share the same alpha subunit but bind to specific seven transmembrane-domain G c...

journal_title：Endocrine

authors： Friedmann S,Dantes A,Amsterdam A

更新日期：2005-04-01 00:00:00

abstract：:To investigate the adrenal effect of a phytosterol (PS) additive, 80 male Japanese quail were divided into four sub-groups and fed 0, 40, 400, and 4,000 ppm of PS, respectively, for 21 days. Subsequently, 50% of the birds from each dosage group were subjected to a 6-day adrenal function test, whereby they were injecte...

journal_title：Endocrine

authors： Liu F,Chen J,Shi F,Wang T,Watanabe G,Taya K

更新日期：2012-04-01 00:00:00

abstract：:Hypopituitarism reduces life expectancy and increases the risk of cardiovascular and cerebrovascular diseases, as well as death. Abnormalities in the cardiovascular system may be independently related to GH deficiency (GHD). The aim of this study was to prospectively investigate coronary flow reserve and diastolic fun...

journal_title：Endocrine

authors： Boschetti M,Agosti S,Albanese V,Casalino L,Teti C,Bezante GP,Brunelli C,Albertelli M,Ferone D

更新日期：2017-02-01 00:00:00

abstract：:Our aim was to evaluate the effectiveness of off-label use of sunitinib in patients with advanced differentiated thyroid carcinoma (DTC) refractory to radioactive iodine (RAI) therapy. We performed a retrospective analysis of patients treated in the setting of clinical practice in a University General Hospital. Eleven...

journal_title：Endocrine

authors： Díez JJ,Iglesias P,Alonso T,Grande E

更新日期：2015-03-01 00:00:00

abstract：:Interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) are synthesized and released from adrenal cells. Therefore, the effects of TNF-alpha and IL-6 on cortisol release from bovine zona fasciculata (ZF) cells were investigated. IL-6 (10-1000 pg/mL) significantly increased basal and adrenocorticotropic hormon...

journal_title：Endocrine

authors： Barney M,Call GB,McIlmoil CJ,Husein OF,Adams A,Balls AG,Oliveira GK,Miner EC,Richards TA,Crawford BK,Heckmann RA,Bell JD,Judd AM

更新日期：2000-12-01 00:00:00

abstract：:RU486 has been reported to be a glucocorticoid receptor (GR) and a progesterone receptor (PR) antagonist. We have analysed RU486 activity on the GR in WCL-2 (CHO) cells and in COS-7 cells transiently transfected with the mouse GR and with the reporter MMTVCAT (MCAT). These cell lines do not contain any active progeste...

journal_title：Endocrine

authors： Zhang S,Danielsen M

更新日期：1995-01-01 00:00:00

abstract：:Adrenocorticotropin-secreting pituitary tumor represents about 10 % of pituitary adenomas and at the time of diagnosis most of them are microadenomas. Transsphenoidal surgery is the first-line treatment of Cushing's disease and accurate localization of the tumor within the gland is essential for selectively removing t...

journal_title：Endocrine

authors： Vitale G,Tortora F,Baldelli R,Cocchiara F,Paragliola RM,Sbardella E,Simeoli C,Caranci F,Pivonello R,Colao A,A.B.C. Group.

更新日期：2017-03-01 00:00:00