Improved prediction of palmitoylation sites using PWMs and SVM.

abstract：:Marine species are comprising about a half of the whole global biodiversity; the sea offers an enormous resource for novel bioactive compounds. Several of the marine origin species show multifunctional bioactivities and characteristics that are useful for a discovery and/or reinvention of biologically active compounds...

journal_title：Protein and peptide letters

authors： Chandra R,Parra R,Iqbal HM

更新日期：2017-01-01 00:00:00

abstract：:Mastoparans are tetradecapeptides found to be the major component of wasp venoms. These peptides possess a variety of biological activities. Three related mastoparans, mastoparan from Polistes jadwagae (MP-PJ), mastoparanX (MP-X) and its carboxyl-free C-terminal form (MP-X-COO-), were crystallized. X-ray diffraction d...

journal_title：Protein and peptide letters

authors： Wang F,Liu X,Li H,Lang X,Peng H,Liu S,Jiang T

更新日期：2006-01-01 00:00:00

abstract：:Discriminating cell wall lytic enzymes from non lytic enzymes is a very important task for curing bacterial infections. In this paper, based on Chou's amphiphilic pseudo amino acid composition, we develop fisher-discriminant based classifier to predict cell wall lytic enzymes. Experiments show that 66.7% sensitivity w...

journal_title：Protein and peptide letters

authors： Ding H,Luo L,Lin H

更新日期：2009-01-01 00:00:00

abstract：:The renin-angiotensin system (RAS) has two different axes, the classical one with the effector peptide angiotensin II and the new one with the effector peptide angiotensin (1-7). Both peptides have been shown to be involved in the pathogenesis of diabetes mellitus and its consequences, nephropathy, retinopathy and car...

journal_title：Protein and peptide letters

authors： Rein J,Bader M

更新日期：2017-11-17 00:00:00

abstract：:In recent years, therapeutic proteins have become an important growing class of drugs in the pharmaceutics industry. The development of recombinant DNA technology has caused to appreciation of therapeutic value of many proteins and peptides in medicine. Currently, approximately 100 therapeutic proteins obtained approv...

journal_title：Protein and peptide letters

authors： Ozgur A,Tutar Y

更新日期：2013-12-01 00:00:00

abstract：:Coordination of cell growth and cell division is very important for living organisms in order for these to develop harmonically. The present research is concerned with the purification and characterization of a new peptide hormone, namely ZmIGF (Zea mays insulin-like growth factor), which regulates growth and cell div...

journal_title：Protein and peptide letters

authors： Rodríguez-López CD,Rodríguez-Romero A,Aguilar R,de Jiménez ES

更新日期：2011-01-01 00:00:00

abstract：:A new galactose-specific lectin, named BBL, was purified from seeds of Bauhinia bauhinioides by precipitation with ammonium sulfate, followed by two steps of ion exchange chromatography. BBL haemagglutinated rabbit erythrocytes (native and treated with proteolytic enzymes) showing stability even after exposure to 60 °...

journal_title：Protein and peptide letters

authors： Silva HC,Bari AU,Pereira-Jénior FN,Simões RC,Barroso-Neto IL,Nobre CB,Pereira MG,Nascimento KS,Rocha BA,Delatorre P,Nagano CS,Assreuy AM,Cavada BS

更新日期：2011-04-01 00:00:00

abstract：:Behcet's disease (BD) is a recurrent pathema with a typical symptom of inflammation involved in many organs. Previous report indicated that the serum of Korean patients with BD stimulates membrane expression of hnRNP A2/B1 in endothelial cells. In this study, the target 35 kDa recombinant human hnRNP A2/B1 were over-e...

journal_title：Protein and peptide letters

authors： Liang J,Yang W,Meng X,Chen P,Du H

更新日期：2015-01-01 00:00:00

abstract：:Loxosceles intermedia spider venom was subjected to proteomic analysis through a MudPIT shot-gun approach to identify the protein composition. Were identified 39 proteins which seem to responsible by the lesion of different types of tissues, to some physiopathological actions and by the prevention of structural damage...

journal_title：Protein and peptide letters

authors： dos Santos LD,Dias NB,Roberto J,Pinto AS,Palma MS

更新日期：2009-01-01 00:00:00

abstract：:The interaction of nickel tetra sulfunated phthalocyanine( NiTSPc) with human serum albumin (HSA), in 20 mM phosphate buffer pH 7.4 was investigated using advanced techniques including fluorescence, synchronous fluorescence, Fourier transform infrared (FT-IR), circular dichroism (CD) spectroscopy and molecular docking...

journal_title：Protein and peptide letters

authors： Dezhampanah H,Firouzi R,Hasani L

更新日期：2016-01-01 00:00:00

abstract：:The high technical standard of current peptide chemistry, which has evolved over the past three decades, has profoundly facilitated the investigation of proteins and their interactions with other molecules at the level of individual amino acids. Using currently available peptide synthesis methods, sequentially continu...

journal_title：Protein and peptide letters

authors： Eichler J

更新日期：2004-08-01 00:00:00

abstract：:A thermostable uricase identified in Bacillus firmus DWD-33, which was isolated for the first time from soil, with an apparent molecular weight of 33.5 kDa was stable against oxidants and SDS. The highest expression yields were obtained in medium containing 0.8% maltose and 1.2% soybean powder as carbon and nitrogen s...

journal_title：Protein and peptide letters

authors： Kotb E

更新日期：2015-01-01 00:00:00

abstract：:We used a de novo designed, beta-hairpin forming T1 peptide as a model to investigate the kinetics of peptide fibrogenesis by a combination of light scattering (LS), circular dichroism (CD), fluorescence, and atomic force microscopy (AFM). The results demonstrate that the T1 fibrogenesis undergoes a consecutive stepwi...

journal_title：Protein and peptide letters

authors： Wang C,Sha Y

更新日期：2010-04-01 00:00:00

abstract：:Antimicrobial peptides (AMPs) represent a large and ubiquitous group of peptides. The current crisis in antibiotic therapy has led to an intensified search for new antimicrobial agents. In this regard, scorpion venom constitutes a rich source of biologically active peptides including AMPs. In the present study, the pu...

journal_title：Protein and peptide letters

authors： Dueñas-Cuellar RA,Kushmerick C,Naves LA,Batista IF,Guerrero-Vargas JA,Pires OR Jr,Fontes W,Castro MS

更新日期：2015-01-01 00:00:00

abstract：:The study of rat proteins is an indispensable task in experimental medicine and drug development. The function of a rat protein is closely related to its subcellular location. Based on the above concept, we construct the benchmark rat proteins dataset and develop a combined approach for predicting the subcellular loca...

journal_title：Protein and peptide letters

authors： Shi R,Xu C

更新日期：2011-06-01 00:00:00

abstract：:A pivotal feature that underlies the development of neurodegeneration is the accumulation of protein aggregates. In response, eukaryotic cells have evolved sophisticated quality control mechanisms to identify, repair and/or eliminate the misfolded abnormal proteins. Chaperones identify any otherwise abnormal conformat...

journal_title：Protein and peptide letters

authors： Eldeeb MA,Ragheb MA,Esmaili M,Hussein F

更新日期：2020-01-01 00:00:00

abstract：:The superoxide anion radical is a highly reactive toxic species produced during the metabolic processes. A number of copper (II) complexes with amino acids and peptides are known to show superoxide dismutase (SOD) like activity. The design and application of synthetic low molecular weight metal complexes as SOD mimics...

journal_title：Protein and peptide letters

authors： Singh RK,Srivastava VC,Singh UP

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:In the last years, Antimicrobial Peptides (AMPs) and lipopeptides have received attention as promising candidates to treat infections caused by resistant microorganisms. OBJECTIVE:The main objective of this study was to investigate the effect of repetitive KLFK motifs and the attachment of aliphatic acids t...

journal_title：Protein and peptide letters

authors： Húmpola MV,Rey MC,Spontón PG,Simonetta AC,Tonarelli GG

更新日期：2019-01-01 00:00:00

abstract：:Background. Obesity is a major health problem in both developed and emerging countries. Obesity is a complex disease whose etiology involves genetic factors in strong interplay with environmental determinants and lifestyle. The discovery of genetic factors and biological pathways underlying human obesity is hampered b...

journal_title：Protein and peptide letters

authors： Martelli PL,Fontanesi L,Piovesan D,Fariselli P,Casadio R

更新日期：2014-01-01 00:00:00

abstract：:Red blood cell (RBC) encapsulated L-asparaginase is a novel therapeutic for the treatment of asparagine auxotrophic malignancies. The enzyme-loaded red blood cells function as bioreactors to deplete bloodstream substrate. This delivery system provides improved pharmacodynamics with protection from circulating proteoly...

journal_title：Protein and peptide letters

authors： Agrawal V,Woo JH,Borthakur G,Kantarjian H,Frankel AE

更新日期：2013-04-01 00:00:00

abstract：:Bromelain inhibitor, "bromein", is a proteinase-inhibitor specific to the cysteine proteinase bromelain from pineapple stem. In the stem, eight bromein isoforms are known to exist, and each isoform has a short peptide (light chain) and a long one (heavy chain) with five disulfide bonds. The three-dimensional structure...

journal_title：Protein and peptide letters

authors： Hatano KI,Takahashi K,Tanokura M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Ciprofloxacin (Cip) is the most commonly used quinolone in clinical practice; however large-scale use has favored the increase of multiresistant pathogenic microorganisms. Antimicrobial peptides (AMPs) appear to be a promising alternative in potentiating these conventional drugs. OBJECTIVE:The aim of this s...

journal_title：Protein and peptide letters

authors： Carneiro VA,de Oliveira ST,Silva RL,de Sousa Duarte H,Silva ML,Matos MNC,Cavalcante RMB,Figueira CS,Lorenzón EN,Cilli EM,da Cunha RMS

更新日期：2020-01-01 00:00:00

abstract：:Oblique orientated alpha-helices are highly specialised protein structural elements that penetrate membranes at a shallow angle and are used to promote membrane destabilisation by a number of protein classes. Here, the use of extended hydrophobic moment methodology shows that the amphibian extrudates, aurein 1.2 and c...

journal_title：Protein and peptide letters

authors： Dennison SR,Harris F,Phoenix DA

更新日期：2005-01-01 00:00:00

abstract：:Identification on protein folding types is always based on the 27-class folds dataset, which was provided by Ding & Dubchak in 2001. But with the avalanche of protein sequences, fold data is also expanding, so it will be the inevitable trend to improve the existing dataset and expand more folding types. In this paper,...

journal_title：Protein and peptide letters

authors： Liu L,Hu XZ,Liu XX,Wang Y,Li SB

更新日期：2012-04-01 00:00:00

abstract：:Bacterial ADP-ribosyltransferases (BADPRTs) are extensively contributed to determine the strain-specific virulence state and pathogenesis in human hosts. Understanding molecular evolution and functional diversity of the BADPRTs is an important standpoint to describe the fundamental behind in the vaccine designing for ...

journal_title：Protein and peptide letters

authors： Chellapandi P,Sakthishree S,Bharathi M

更新日期：2013-09-01 00:00:00

abstract：:In this article we review the current status of our understanding of membrane mediated interactions from theory and experiment. Phenomenological mean field and molecular models will be discussed and compared to recent experimental results from dynamical neutron scattering and atomic force microscopy. ...

journal_title：Protein and peptide letters

authors： Armstrong CL,Sandqvist E,Rheinstädter MC

更新日期：2011-04-01 00:00:00

abstract：:Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 A resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered alpha-neurotoxin posses...

journal_title：Protein and peptide letters

authors： Murakami MT,Kini RM,Arni RK

更新日期：2009-01-01 00:00:00

abstract：:Currently, prion phenomena have been detected in various organisms, in addition to mammals affected by transmissible spongiform encephalopathies. In the budding yeast Saccharomyces cerevisiae, various proteins have prion properties and adopt atypical phenotypes as genetic elements, such as the Sup35 and Ure2 proteins,...

journal_title：Protein and peptide letters

authors： Inoue Y

更新日期：2009-01-01 00:00:00

abstract：:An alternative method for expressing the recombinant proteins in Escherichia coli is proposed. Unlike the ordinary induction protocol where the cells in the early- to mid-log phase are induced for the protein production, this alternative protocol utilizes the cells in the stationary phase. By using a glutathione S-tra...

journal_title：Protein and peptide letters

authors： Chae YK,Cho KS,Chun W,Lee K

更新日期：2003-08-01 00:00:00

abstract：:Hepatitis C virus and related viruses in the Flaviviridae family (such as dengue virus, yellow fever virus or West Nile virus) are amongst the most important human pathogens, causing substantial morbidity and mortality world-wide. The production of viral progeny in Flaviviridae is orchestrated by the small, multifunct...

journal_title：Protein and peptide letters

authors： Ivanyi-Nagy R,Darlix JL

更新日期：2010-08-01 00:00:00