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Compliance and schizophrenia: the predictive potential of insight into illness, symptoms, and side effects.

Abstract：

BACKGROUND:Personal beliefs about medication compliance have been reliably associated with emotional and behavioral response to mental health problems and health outcomes. This notion has been extensively explored in relation to mental illness. In the current study, a questionnaire designed to assess beliefs about medication compliance (the medication adherence rating scale [MARS]) was translated into Taiwanese to explore beliefs about compliance in schizophrenic patients. METHODS:In this cross-sectional study, 104 patients who met Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria for schizophrenic disorders were recruited and independently interviewed. We first determined the psychometric properties of the translated MARS, including internal consistency, test-retest reliability, and construct validity. In addition, we investigated the relationships between medication compliance and clinical variables through correlation and regression analyses. RESULTS:We found that the translated MARS was a simple and reliable self-reported compliance scale. Furthermore, in this exploratory study, we found that patients with better medication compliance had better insight into mental illness, less severe psychopathologic condition, and less negative subjective response to side effects of antipsychotics. CONCLUSIONS:Additional research focusing on these patient outcomes will be of great interest and value in elucidating the role of medication compliance in management of schizophrenic patients.

journal_name

Compr Psychiatry

journal_title

Comprehensive psychiatry

authors

Kao YC,Liu YP

doi

10.1016/j.comppsych.2010.03.007

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

557-65

issue

6

eissn

0010-440X

issn

1532-8384

pii

S0010-440X(10)00029-5

journal_volume

51

pub_type

杂志文章

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