Abstract：
OBJECTIVE:Rheumatoid arthritis is associated with increased cardiovascular morbidity and mortality. We performed a systematic review of the literature and a meta-analysis to look for differences in the prevalence of traditional cardiovascular risk factor between RA patients and controls. METHODS:Medline database was searched to identify studies evaluating the prevalence of traditional cardiovascular risk factors in rheumatoid arthritis patients and controls. Studies were selected and reviewed by two investigators. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated and pooled using a random-effects model. Statistical heterogeneity was evaluated through the use of Chi2 and I2 statistics. RESULTS:Fifteen case-control studies with a total of 2956 patients and 3713 controls met the inclusion criteria. The prevalence of smoking was increased in RA patients in comparison with controls: OR (95%CI) 1.56 (1.35-1.80) (P < 0.00001). The prevalence of hypertension did not differ: OR (95% CI) 1.09 (0.91-1.31) (P = 0.35). The prevalence of diabetes mellitus was increased in RA: OR (95%CI) 1.74 (1.22-2.50) (P = 0.003). The prevalence of hypercholesterolemia did not differ: OR (95%CI) 0.84 (0.67-1.04) (P = 0.11). HDL cholesterol levels were lower in RA patients: weighted mean difference -17.72 mg/dl (-18.35 - -17.08) (P < 0.00001). Significant heterogeneity among studies was found for diabetes mellitus and HDL cholesterol levels. CONCLUSIONS:Some traditional cardiovascular risk factors, such as smoking, diabetes mellitus or lower HDL cholesterol levels, appear more prevalent in rheumatoid arthritis patients and could contribute to the increased cardiovascular morbidity and mortality observed in rheumatoid arthritis.
journal_name
Joint Bone Spinejournal_title
Joint bone spineauthors
Boyer JF,Gourraud PA,Cantagrel A,Davignon JL,Constantin Adoi
10.1016/j.jbspin.2010.07.016subject
Has Abstractpub_date
2011-03-01 00:00:00pages
179-83issue
2eissn
1297-319Xissn
1778-7254pii
S1297-319X(10)00212-5journal_volume
78pub_type
杂志文章,meta分析,评审相关文献
JOINT BONE SPINE文献大全abstract：OBJECTIVES:To compare the differences or correlation between the results obtained from a generic and a disease-specific instrument for the study group and to assess the short-term effects of spa therapy on quality of life of patients with knee osteoarthritis. PATIENTS AND METHODS:Fifty patients with knee osteoarthriti...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2003.09.008
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVE:To investigate the prevalence of diffuse idiopathic skeletal hyperostosis (DISH) in ancient populations. MATERIAL AND METHODS:We studied 38 women and 61 men aged at least 30 years at death, whose remains were recovered from four cemeteries of the High Middle Ages (VIth to VIIIth century) located in Lorraine ...
journal_title：Joint bone spine
pub_type： 历史文章,杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:Histone deacetylase inhibitors (HDIs) are a new class of compounds that are being developed for the treatment of malignancies such as cutaneous T-cell lymphoma. HDIs inhibit the removal of acetyl groups from histones. The histone acetylation process is dependent on two enzymes, histone acetyl transferase (HAT) and his...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2010.03.009
更新日期：2010-10-01 00:00:00
abstract：:In the 20-50-year age group, hip pain usually indicates dysplasia. Chronic mechanical pain is the usual pattern, although acute pain caused by avulsion or degeneration of the labrum may occur. The morphological characteristics of the dysplastic hip should be evaluated, and the link between the dysplasia and the osteoa...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2006.09.001
更新日期：2006-12-01 00:00:00
abstract：OBJECTIVES:Some immunological abnormalities have been described in seronegative spondyloarthropathies (SpA). The aim of this study is to determine the serum levels of IL-1beta, TNF-alpha and IL-8, which are proinflammatory cytokines in active and inactive patients with SpA, to compare the results with those of controls...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/s1297-319x(02)00431-1
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the geoepidemiology of Sjögren's syndrome (SS) in Latin America. METHODS:This was a three phase study in which original data from a Colombian cohort of patients with SS is presented, followed by a systematic review of Colombian and Latin American studies. Lastly, the geoepidemiology of SS in Lati...
journal_title：Joint bone spine
pub_type： 杂志文章,meta分析
doi：10.1016/j.jbspin.2019.02.004
更新日期：2019-10-01 00:00:00
abstract：:Musculoskeletal symptoms are not infrequent in leprosy and, when inaugural, may be difficult to differentiate from other conditions, most notably rheumatoid arthritis. We report the case of a 24 year-old man with a 5 year history of intermittent inflammatory arthritis and fever. Physical findings and radiographs were ...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2005.03.014
更新日期：2006-05-01 00:00:00
abstract：:Bronchiectasis is an uncommon pulmonary manifestation of systemic sclerosis (SSc). We report the case of a 70-year-old woman with CREST syndrome and vasculitis who developed multifocal symptomatic bronchiectasis. The bronchiectasis and immunosuppressive therapy precipitated severe lower respiratory tract infection, wh...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/s1297-319x(02)00441-4
更新日期：2002-10-01 00:00:00
abstract：:Osteoarthritis is a major public health burden. The incidence of osteoarthritis increases with advancing age. Symptomatic treatments aimed at alleviating the pain and thereby restoring joint function form the basis of the treatment. The chronic course requires long-term treatment with special attention to minimizing t...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2003.09.010
更新日期：2004-07-01 00:00:00
abstract：:Nitric oxide (NO) is attracting considerable interest because it mediates many functions. This gas is ubiquitously produced in the body by three enzymes, called NO synthases. Two NO synthases are constitutively expressed, one in the nervous system and the other in the blood vessels, where it regulates tissue perfusion...
journal_title：Joint bone spine
pub_type： 社论,评审
doi：10.1016/s1297-319x(01)00308-6
更新日期：2001-12-01 00:00:00
abstract：:Calcification of the ligamentum flavum is a rare manifestation of the calcium pyrophosphate dihydrate deposition disease (CPPD). In CPPD deposition disease, spinal involvement is rare. Until now, thoracic spine CPPD causing thoracic cord compression has been reported in only sporadic cases. We report a new case of tho...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2007.01.029
更新日期：2007-10-01 00:00:00
abstract：:We report three new cases of longitudinal femoral shaft fracture due to bone insufficiency and review the eight cases reported in the literature. The typical patient is a woman older than 65 years of age who present with mechanical pain in the thigh and/or groin. Palpation of the thigh may reproduce the pain. The diag...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/s1297-319x(03)00051-4
更新日期：2003-12-01 00:00:00
abstract：OBJECTIVE:To assess if the use of biological marker of bone resorption (CTX) feedback is a mean to improve persistence on monthly oral ibandronate. METHODS:One year prospective multicenter study using a cluster randomisation design with physicians as randomized units into two groups, A and B; in group B, physicians us...
journal_title：Joint bone spine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.jbspin.2011.05.001
更新日期：2012-07-01 00:00:00
abstract：:Demonstration of amyloid deposits in biopsy specimens is the only means of confirming the diagnosis of amyloidosis. In experienced hands, nonsurgical biopsies of the rectal mucosa or, preferably, of the abdominal fat pad or labial salivary glands provide the diagnosis in 80 to 85% of cases. Immunolabeling studies help...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/s1297-319x(02)00449-9
更新日期：2002-12-01 00:00:00
abstract：:Osteoarthritis is the most common joint disease affecting roughly one sixth of the human population. It is also the most common arthritis affecting the temporomandibular joint, often leading to severe pain and the inability to masticate. Animal models are essential to investigate the disease in part because they lend ...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2016.05.016
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:Previous studies reported that anti-CCP antibody positivity predicts good response to rituximab (RTX) in rheumatoid arthritis (RA). A quantitative approach to such possibility could be a good way to detect the subset of patients most likely to respond. We investigated whether serum anti-CCP antibody titres co...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2014.06.001
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:Experimental and clinical data suggest that statins may protect bone by inhibiting bone resorption and/or stimulating bone formation. Interleukin-6 (IL-6) is produced by osteoblasts, and potently stimulates osteoclast activation playing a key role in normal bone resorption as well as in post-menopausal and in...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2012.07.007
更新日期：2013-03-01 00:00:00
abstract：:Recent data suggest that group B streptococcal arthritis is being increasingly diagnosed. We retrospectively reviewed the records of patients admitted to our Teaching Hospital Rheumatology Department for septic arthritis between May 2000 and May 2004 and we reviewed the relevant literature to determine the characteris...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2005.08.007
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the influence of tumor necrosis factor (TNF) blocker on the radiographic progression in ankylosing spondylitis (AS) patients. METHODS:A total of 610 patients were recruited. We stratified two groups (TNF blocker naïve and exposure patients). After then, we analyzed the radiographic spinal progres...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2015.09.006
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVES:Severe hidradenitis suppurativa (HS), under infliximab, can be associated with different forms of arthritis whose mechanism is unclear. Our objective is to establish the frequency and clinical presentation of new-onset arthritis in HS under infliximab. METHODS:Severe HS patients under infliximab were follow...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2015.01.020
更新日期：2015-10-01 00:00:00
abstract：:The objective of this article is to review data on joint distraction used to treat knee osteoarthritis. Joint distraction is a surgical procedure in which the two bony ends of the joint are gradually pulled apart then kept separated for 2 months in an external fixation frame. Weight bearing is continued to ensure vari...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2016.03.004
更新日期：2017-03-01 00:00:00
abstract：:Stickler syndrome is a group of rare genetic conditions (incidence, 1/7500 births) related to mutations in the collagen genes. Both the mutations and the clinical features vary widely across affected patients. The main manifestations are craniofacial birth defects, bone and joint symptoms, ocular abnormalities, and he...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2010.03.012
更新日期：2011-01-01 00:00:00
abstract：:Parkinson's disease is the most common neurodegenerative disease after Alzheimer's disease. On the long term, it may be complicated by various musculoskeletal problems, such as osteoporotic fractures, that have significant socioeconomic consequences. Indeed, patients suffering from Parkinson's disease have a higher fr...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2015.03.009
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:To investigate plasma and synovial fluid (SF) periostin of knee osteoarthritis (OA) patients and to determine the relationship between periostin levels and the radiographic severity. METHODS:A total of 110 subjects (90 knee OA patients and 20 healthy controls) were enrolled in this study. Plasma and SF perio...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2015.01.023
更新日期：2015-10-01 00:00:00
abstract：OBJECTIVES:To assess in one time window cardiovascular risks for both patients with gout and patients with rheumatoid arthritis in a Dutch primary care population. METHODS:Retrospective matched cohort study with data from the electronic health records of 51 Dutch general practices. Participants were patients aged 30 y...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2015.12.003
更新日期：2017-01-01 00:00:00
abstract：:Retroperitoneal fibrosis is a rare inflammatory and fibrotic process in the retroperitoneal peri-aortic tissues, associated with ureters and other abdominal organs' entrapment. Here we report an original observation of a 55-year-old patient presenting with chronic lombalgia disclosing idiopathic retroperitoneal fibros...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2006.12.005
更新日期：2007-10-01 00:00:00
abstract：OBJECTIVE:To describe echographic abnormalities on the proximal (PIP) and distal (DIP) interphalangeal joints of healthy subjects. METHODS:Healthy asymptomatic volunteers under forty were enrolled. Ultrasonography was performed on PIP and DIP 2-5 in the presence of two operators. In B mode, synovial hypertophy and eff...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2008.06.017
更新日期：2009-05-01 00:00:00
abstract：INTRODUCTION:Soccer is a highly osteogenic sport in pubescent adolescents and adults, particularly in weight-bearing bones. However, little is known about its effects in children despite the fact that soccer practice usually starts before puberty. The aim of this study was to verify whether soccer was able to increase ...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2006.12.008
更新日期：2008-01-01 00:00:00
abstract：:Osteoarthritis (OA) is the most common human joint disorder. Its complex pathogenesis remains poorly understood but appears multifactorial. To date, no specific pharmacological agent has been identified to alter the disease course of OA. Calcification of articular cartilage is a hallmark of OA and evidence suggests it...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2010.10.008
更新日期：2011-07-01 00:00:00
abstract：PURPOSE:FRAX™ is a fracture prediction algorithm to determine a patient's absolute fracture risk. There is a growing consensus that osteoporosis treatment should be based on individual 10-year fracture probability, as calculated in the FRAX™ algorithm, rather than on T-scores alone. OBJECTIVE:Our objective was to eval...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2012.01.001
更新日期：2013-01-01 00:00:00
