Abstract：
:Bronchiectasis is an uncommon pulmonary manifestation of systemic sclerosis (SSc). We report the case of a 70-year-old woman with CREST syndrome and vasculitis who developed multifocal symptomatic bronchiectasis. The bronchiectasis and immunosuppressive therapy precipitated severe lower respiratory tract infection, which was fatal within a few months. The concomitant occurrence of bronchiectasis and SSc raises the possibility of a pathophysiological relationship. Several hypotheses can be put forward to explain the occurrence of bronchial wall damage leading to bronchiectasis. Whatever the mechanism, cases of bronchiectasis in patients with SSc should be reported to make physicians aware of the substantial risk associated with this combination.
journal_name
Joint Bone Spinejournal_title
Joint bone spineauthors
Lavie F,Rozenberg S,Coutaux A,Koeger AC,Bourgeois P,Fautrel Bdoi
10.1016/s1297-319x(02)00441-4subject
Has Abstractpub_date
2002-10-01 00:00:00pages
515-8issue
5eissn
1297-319Xissn
1778-7254journal_volume
69pub_type
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