Abstract：
:Osteoarthritis is a major public health burden. The incidence of osteoarthritis increases with advancing age. Symptomatic treatments aimed at alleviating the pain and thereby restoring joint function form the basis of the treatment. The chronic course requires long-term treatment with special attention to minimizing the side effects of drugs. Acetaminophen has a good risk/benefit ratio that has prompted international consensus panels to recommend its use as first-line therapy in dosages of up to 4 g/day. This review discusses safety and efficacy data from randomized double-blind trials of acetaminophen used to alleviate pain caused by osteoarthritis.
journal_name
Joint Bone Spinejournal_title
Joint bone spineauthors
Bertin P,Keddad K,Jolivet-Landreau Idoi
10.1016/j.jbspin.2003.09.010subject
Has Abstractpub_date
2004-07-01 00:00:00pages
266-74issue
4eissn
1297-319Xissn
1778-7254pii
S1297319X03002094journal_volume
71pub_type
杂志文章,评审相关文献
JOINT BONE SPINE文献大全abstract：:Macrophage activation syndrome (MAS) is a rare and serious complication of adult-onset Still's disease. We describe a case in a 49-year-old woman with Still's disease refractory to glucocorticoids, methotrexate, and infliximab. Anakinra provided satisfactory disease control for 1 year, after which escape phenomenon oc...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2013.04.011
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVES:To determine the prevalence and the associations of anti-neutrophil cytoplasmic antibodies (ANCA) and subtypes with clinical, biological, and radiological findings in patients with rheumatoid arthritis (RA). MATERIALS AND METHODS:This is a transversal study of 85 patients with RA (followed in Ibn-i Sina Hos...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2003.04.002
更新日期：2004-05-01 00:00:00
abstract：:Familial arthropathy associated with congenital camptodactyly has been previously recognized as a definite clinical entity in the literature. The clinical spectrum of this disease seems to be variable. The typical features of congenital camptodactyly, arthropathy, coxa vara and pericarditis (CACP syndrome) appear to b...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2013.01.010
更新日期：2013-10-01 00:00:00
abstract：UNLABELLED:IgD myeloma, which is particularly severe, accounts for only 1-3% of all myeloma cases, and the kappa subtype contributes only 10-30% of IgD myelomas. We report a new case. CASE-REPORT:A 59-year-old man was admitted for inflammatory low back pain with L5 sciatica and diffuse bone pain. The symptoms had been...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2003.05.004
更新日期：2004-07-01 00:00:00
abstract：:Disseminated extrapulmonary tuberculosis is uncommon, particularly among immunocompentent individuals. We report the case of a 38-year-old woman from the Ivory Coast who had osteomyelitis in the right humerus, a cold abscess in the pectoralis major muscle, T11 spondylitis, deep lymphadenopathies, peritoneal nodules, a...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2004.05.005
更新日期：2005-05-01 00:00:00
abstract：:Conventional chemotherapies are no longer the only treatment in multiple myelomatosis. High-dose chemotherapy and autologous transplantation are not curative but do increase relapse-free survival time in young patients. Thalidomide is efficacious in refractory and relapsing myeloma and its evaluation is going on. Cura...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/s1297-319x(03)00018-6
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVES:Patients with acromegaly appear to be at increased risk of vertebral fractures despite normal bone mineral density. We investigated the prevalence of vertebral fractures in a cohort of acromegalic patients under 80 years of age. METHODS:Monocentric cross-sectional study performed at Nantes University Hospit...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2020.04.020
更新日期：2020-12-01 00:00:00
abstract：:Once remission or low disease activity (LDA) is attained in established rheumatoid arthritis (RA) patients, attempting disease-modifying anti-rheumatic drug (DMARD) tapering appears to be a viable option to avoid patient overtreatment. Potential benefits include reduction in the treatment burden and the risk of advers...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2018.02.002
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:To analyze the influence of anthropometry at birth on bone status and physical activity aptitudes of adult women. METHODS:Our population was composed of 70 women (17-29 years): 40 athletes and 30 controls. Athletes participated in various long-lasting and high-level weight-bearing sports (10.2 ± 2.2h ours/we...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2010.07.020
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVES:This study was performed to investigate whether leptin mRNA expression is increased from peripheral blood mononuclear cells (PBMCs) of patients with active ankylosing spondylitis (AS) and whether it stimulates the production of pro-inflammatory cytokines. METHODS:Twenty patients with active AS were enrolled...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2008.04.018
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVE:To report our single centre experience in treating 4 children affected by childhood primary central nervous system vasculitis (cPACNS) using mycophenolate mofetil (MMF). METHODS:From December 2011 to August 2015, 4 patients (3 males; age range: 9 months-13 years) affected by cPACNS were collected. Enrolled c...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2016.12.004
更新日期：2017-05-01 00:00:00
abstract：INTRODUCTION:In recent years, studies have boosted our knowledge about the biology and disorders of articular cartilage. In this regard, the design of hydrogel-based scaffolds has advanced to improve cartilage repair. However, the efficacy of knee cartilage repair using hydrogels remains unclear. The aim of systematic ...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2020.105096
更新日期：2020-11-03 00:00:00
abstract：OBJECTIVE:To evaluate the role of endogenous sex steroids on bone mineral density (BMD) in healthy Turkish men. METHODS:Serum total testosterone (TT), free testosterone (FT), dehydroepiandrosterone sulfate and estradiol levels were assayed in 174 healthy men of 240 volunteers, aged 22-76 years. Dual-energy X-ray absor...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2005.04.003
更新日期：2006-01-01 00:00:00
abstract：UNLABELLED:The role of epidural fibrosis in postoperative sciatica is unclear. Few therapeutic trials have been published. We evaluated the mechanical effects of forceful saline injections through the sacrococcygeal hiatus comparatively with glucocorticoid injections. PATIENTS AND METHODS:Forty-seven patients with pos...
journal_title：Joint bone spine
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s1297-319x(00)00234-7
更新日期：2001-02-01 00:00:00
abstract：:Primary hyperparathyroidism is common, particularly in postmenopausal women. Since the introduction of routine automated serum calcium assays and the development of assays for intact 1-84 parathyroid hormone, the diagnosis is usually made fortuitously in asymptomatic patients or during evaluation for osteoporosis. As ...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2007.03.004
更新日期：2008-03-01 00:00:00
abstract：:We present a case of giant chronic expanding hematoma occurring in the left lateral thigh without any history of trauma or chronic medical disease. In our case, a diagnosis was unable to perform through conventional diagnosis method, which was confirmed by histopathological examination after successful surgical treatm...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2007.01.041
更新日期：2008-01-01 00:00:00
abstract：:During the last decade, articular ultrasonography (US) has been found effective in evaluating inflammatory, degenerative, and traumatic abnormalities of articular and periarticular tissues. In clinical practice, US used in combination with a thorough clinical evaluation can help rheumatologists to confirm or to refute...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/s1297-319x(02)00394-9
更新日期：2002-05-01 00:00:00
abstract：:Retroperitoneal fibrosis is a rare inflammatory and fibrotic process in the retroperitoneal peri-aortic tissues, associated with ureters and other abdominal organs' entrapment. Here we report an original observation of a 55-year-old patient presenting with chronic lombalgia disclosing idiopathic retroperitoneal fibros...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2006.12.005
更新日期：2007-10-01 00:00:00
abstract：:Interferons (IFNs) play essential roles in regulating osteoclast differentiation and bone resorption. Over the last decade, we have seen tremendous developments in our understanding of the mechanisms by which interferons regulate osteoclastogenesis. Of the type I interferons, IFN-β inhibits osteoclastogenesis via auto...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2015.07.010
更新日期：2016-05-01 00:00:00
abstract：:We report the use of intra-articular Botulinum toxin A in two RA patients with persistently painful monoarthritis in ankle/feet joints. Both patients had monarticular pain despite a good response of all other joints to a combination therapy that included anti-tumor necrosis factor therapy. Both patients had failed int...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2008.05.006
更新日期：2009-03-01 00:00:00
abstract：:Biotherapies and other new treatments introduced over the last few years have considerably enriched the therapeutic armamentarium for rheumatoid arthritis. Nevertheless, primary refractoriness or secondary escape phenomenon may occur, indicating a need for identifying new treatment targets. Promising candidates can be...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2004.03.004
更新日期：2004-11-01 00:00:00
abstract：:Recent progress in the management of rheumatoid arthritis (RA) is turning attention toward comorbidities, such as diabetes. The objectives of this review are to clarify the links between RA and diabetes and to assess potential effects of disease-modifying antirheumatic drugs (DMARDs) on diabetes. The increased insulin...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2016.09.001
更新日期：2017-07-01 00:00:00
abstract：OBJECTIVES:To investigate the diagnostic accuracy of ultrasound and conventional radiography in the evaluation of calcium pyrophosphate crystal deposits at wrist level. METHODS:Consecutive patients with a "definite" diagnosis of calcium pyrophosphate deposition disease and disease-controls were prospectively included ...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2020.04.012
更新日期：2020-12-01 00:00:00
abstract：:Vertebral Paget's disease produces a large panel of radiologic appearances sometimes atypical and pseudotumoral. Classical classifications of bone alterations based on pathophysiological hypotheses do not always match the imaging findings. This article will review the computed tomography (CT) and magnetic resonance im...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2014.07.009
更新日期：2015-01-01 00:00:00
abstract：:Rheumatology deals with many different entities among which dys/autoimmune diseases occupy a position of preponderance. This review focuses on the concept of complex genetic disease, which is illustrated by three different chronic inflammatory joint diseases: rheumatoid arthritis, systemic lupus erythematosus, and sys...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2009.10.002
更新日期：2009-12-01 00:00:00
abstract：:Reported here is a 21-year-old female with isolated contracture of the rectus femoris muscle. Its possible relation to breech positioning, and the role of sonography for its diagnosis and close follow-up are discussed in the light of the relevant literature. ...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2010.07.013
更新日期：2011-01-01 00:00:00
abstract：:The gradual reductions in bone mass and skeletal calcium density seen throughout adulthood occur in parallel with changes in the production of bioactive sex hormones in both men and women. The long-held belief that osteoporosis is dependent on androgens in men and estrogens in women has been challenged by recent repor...
journal_title：Joint bone spine
pub_type： 杂志文章,评审
doi：10.1016/j.jbspin.2004.04.004
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVES:Only a few studies have identified prognostic factors indicating risk of future knee arthroplasty in patients with osteoarthritis (OA) of the knee. The Osteoarthritis Initiative (OAI) is a National Institutes of Health and privately funded cohort study of 4796 persons with or at high risk of knee OA. The OAI...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/j.jbspin.2011.05.005
更新日期：2012-05-01 00:00:00
abstract：:Gout secondary to lead-induced nephropathy is a long-term complication of occupational lead exposure. We report a case of this now-rare condition. The patient was a 63-year-old man who had been a miner from 1950 to 1970. Thirty years after cessation of his exposure to lead, he experienced onset of inflammatory symmetr...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/s1297-319x(02)00420-7
更新日期：2002-06-01 00:00:00
abstract：:A case of severe hyperparathyroidism (HPT), secondary to chronic renal failure, with massive distal phalangeal osteolysis is reported. After parathyroidectomy, brachydactyly and osteosclerosis of the distal phalanges were observed; the phalanx of the thumbs healed with shortened and sclerotic beaked appearance. These ...
journal_title：Joint bone spine
pub_type： 杂志文章
doi：10.1016/s1297-319x(03)00023-x
更新日期：2003-03-01 00:00:00
