Androgens and bone metabolism.

Abstract:

:The gradual reductions in bone mass and skeletal calcium density seen throughout adulthood occur in parallel with changes in the production of bioactive sex hormones in both men and women. The long-held belief that osteoporosis is dependent on androgens in men and estrogens in women has been challenged by recent reports of osteoporosis in young men with normal testosterone levels but extremely low estrogen levels. A review of the literature indicates that estrogens have a far greater influence on bone mass than do androgens. This may suggest new approaches to the treatment of male osteoporosis. Furthermore, osteoporosis induced by prostate cancer treatment should receive greater medical attention.

journal_name

Joint Bone Spine

journal_title

Joint bone spine

authors

Alexandre C

doi

10.1016/j.jbspin.2004.04.004

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

202-6

issue

3

eissn

1297-319X

issn

1778-7254

pii

S1297319X04001010

journal_volume

72

pub_type

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    pub_type: 杂志文章

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