Abstract:
:Radioisotope synovectomy has been extensively used to treat patients with chronic inflammatory joint disease but has moved to a less prominent position since the introduction of new and highly effective drugs. Remaining indications are refractory synovitis, pigmented villonodular synovitis as an adjunct to surgery, and hemophilic arthropathy. The three main radioisotopes used are yttrium-90, rhenium-186, and erbium-189. Radioisotope synovectomy should be performed only by highly experienced professionals, to minimize the risk of injection-related complications. The available safety data, in particular regarding the risk of malignancy, are reassuring. The efficacy of yttrium-90 in chronic inflammatory joint disease remains controversial.
journal_name
Joint Bone Spinejournal_title
Joint bone spineauthors
André V,Dalibard V,Dernis E,Varin S,Cormier Gdoi
10.1016/j.jbspin.2017.06.002subject
Has Abstractpub_date
2018-05-01 00:00:00pages
295-299issue
3eissn
1297-319Xissn
1778-7254pii
S1297-319X(17)30128-8journal_volume
85pub_type
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