Current role for radioisotope synovectomy.

Abstract:

:Radioisotope synovectomy has been extensively used to treat patients with chronic inflammatory joint disease but has moved to a less prominent position since the introduction of new and highly effective drugs. Remaining indications are refractory synovitis, pigmented villonodular synovitis as an adjunct to surgery, and hemophilic arthropathy. The three main radioisotopes used are yttrium-90, rhenium-186, and erbium-189. Radioisotope synovectomy should be performed only by highly experienced professionals, to minimize the risk of injection-related complications. The available safety data, in particular regarding the risk of malignancy, are reassuring. The efficacy of yttrium-90 in chronic inflammatory joint disease remains controversial.

journal_name

Joint Bone Spine

journal_title

Joint bone spine

authors

André V,Dalibard V,Dernis E,Varin S,Cormier G

doi

10.1016/j.jbspin.2017.06.002

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

295-299

issue

3

eissn

1297-319X

issn

1778-7254

pii

S1297-319X(17)30128-8

journal_volume

85

pub_type

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