Thalidomide: a comeback?

Abstract:

:Thalidomide, a synthetic glutamic acid derivative first marketed in 1954 as a sedative, rapidly gained worldwide notoriety as a cause of phocomelia. To prevent further cases of this severe birth defect, thalidomide was removed from the market. Over the last few years, however, thalidomide has been found to exhibit properties of potential usefulness in a range of conditions. Trials are under way in rheumatic diseases, and safer analogs have been developed.

journal_name

Joint Bone Spine

journal_title

Joint bone spine

authors

Wendling D,Toussirot E,Michel F

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

259-61

issue

4

eissn

1297-319X

issn

1778-7254

journal_volume

67

pub_type

社论,评审
  • Usefulness of intra-articular botulinum toxin injections. A systematic review.

    abstract:UNLABELLED:Botulinum toxin is a proven and widely used treatment for numerous conditions characterized by excessive muscular contractions. Recent studies have assessed the analgesic effect of botulinum toxin in joint pain and started to unravel its mechanisms. LITERATURE-SEARCH-METHODOLOGY:We searched the internationa...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2015.10.001

    authors: Khenioui H,Houvenagel E,Catanzariti JF,Guyot MA,Agnani O,Donze C

    更新日期:2016-03-01 00:00:00

  • Development of temporomandibular joint arthritis: The use of animal models.

    abstract::Osteoarthritis is the most common joint disease affecting roughly one sixth of the human population. It is also the most common arthritis affecting the temporomandibular joint, often leading to severe pain and the inability to masticate. Animal models are essential to investigate the disease in part because they lend ...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2016.05.016

    authors: Ghassemi Nejad S,Kobezda T,Tar I,Szekanecz Z

    更新日期:2017-03-01 00:00:00

  • New treatment targets in osteoporosis.

    abstract::Postmenopausal osteoporosis is characterized by bone remodeling alterations with an imbalance between excessive bone resorption and inadequate bone formation. At present, osteoporosis treatment rests on bone resorption inhibitors and, more specifically, on bisphosphonates. However, the introduction of anabolic agents ...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2010.02.004

    authors: Roux S

    更新日期:2010-05-01 00:00:00

  • Upper cervical spine surgery in rheumatoid arthritis: retrospective study of 30 patients followed for two years or more after Cotrel-Dubousset instrumentation.

    abstract:PURPOSE:To evaluate the efficacy of upper cervical spine surgery in symptomatic atlantoaxial instability due to rheumatoid arthritis (RA). MATERIAL AND METHODS:Thirty RA patients (29 women and one man) with a mean age of 56 years were studied retrospectively. Symptomatic forward slippage of the atlas on the axis with ...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:

    authors: Pham XV,Bancel P,Menkès CJ,Kahan A

    更新日期:2000-01-01 00:00:00

  • Tocilizumab controls bone turnover in early polymyalgia rheumatica.

    abstract:OBJECTIVES:This study explores changes in the bone homeostasis by testing the N-terminal collagen type I extension propeptide (PINP) marker for osteo-formation and the carboxy-terminal region of collagen type I (CTX-I) marker for osteo-resorption in patients taking tocilizumab for polymyalgia rheumatica (PMR). METHODS...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2020.105117

    authors: Carvajal Alegria G,Garrigues F,Bettacchioli E,Loeuille D,Saraux A,Cornec D,Devauchelle-Pensec V,Renaudineau Y

    更新日期:2020-12-07 00:00:00

  • Kimura disease of extremity: unusual manifestation in a long bone.

    abstract::Kimura's disease is a rare, chronic inflammatory disorder, presenting usually as head and neck swellings and regional cervical lymphadenopathy. The disease is more often described from oriental literature but the osseous manifestations and involvement of extremity are rare and unidentified in literature. We present an...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2007.07.020

    authors: Varshney MK,Kumar A,Khan SA,Yadav CS

    更新日期:2008-07-01 00:00:00

  • TNFalpha antagonist therapy in ankylosing spondylitis and psoriatic arthritis: recommendations of the French Society for Rheumatology.

    abstract:OBJECTIVES:To develop recommendations for TNFalpha antagonist therapy in patients with spondyloarthropathies. METHODS:The Delphi consensus procedure was used to select questions, to which evidence-based answers were sought in the literature. Expert opinion was used when needed to estimate the risks and benefits of TNF...

    journal_title:Joint bone spine

    pub_type: 杂志文章,实务指引

    doi:10.1016/j.jbspin.2006.02.005

    authors: Pham T,Guillemin F,Claudepierre P,Luc M,Miceli-Richard C,Fautrel B,de Bandt M,Breban M,Goupille P,Maillefert JF,Masson C,Saraux A,Schaeverbeke T,Wendling D,Mariette X,Combe B,Club Rhumatismes et Inflammation (CRI).,Soci

    更新日期:2006-10-01 00:00:00

  • Multiple vertebral osteonecrosis.

    abstract::Vertebral osteonecrosis classically presents with an intravertebral vacuum cleft phenomenon or a fluid-filled cleft on MR images. These clefts are usually found in older patients presenting with more severe fractures, more significant collapse and instability. Therefore, although considered for a long time as pathogno...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2007.05.010

    authors: Javier RM,Moser T,Dietemann JL,Sparsa L,Natarajan-Ame S,Chenard MP,Kuntz JL

    更新日期:2008-05-01 00:00:00

  • Time trends in the incidence, prevalence, and severity of rheumatoid arthritis: A systematic literature review.

    abstract:INTRODUCTION:Rheumatoid arthritis (RA) generates a heavy socioeconomic burden. The ability to predict the frequency and severity of socioeconomic effects due to RA is crucial to the development of public health policies. OBJECTIVE:To conduct a systematic literature review of data on the prevalence, incidence, and seve...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2016.07.007

    authors: Minichiello E,Semerano L,Boissier MC

    更新日期:2016-12-01 00:00:00

  • Traditional cardiovascular risk factors in rheumatoid arthritis: a meta-analysis.

    abstract:OBJECTIVE:Rheumatoid arthritis is associated with increased cardiovascular morbidity and mortality. We performed a systematic review of the literature and a meta-analysis to look for differences in the prevalence of traditional cardiovascular risk factor between RA patients and controls. METHODS:Medline database was s...

    journal_title:Joint bone spine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jbspin.2010.07.016

    authors: Boyer JF,Gourraud PA,Cantagrel A,Davignon JL,Constantin A

    更新日期:2011-03-01 00:00:00

  • Intermittent parathyroid hormone therapy to increase bone formation.

    abstract::Clinical data suggested that parathyroid hormone (PTH) might be effective in improving bone mass in patients with osteoporosis, providing its resorptive effects, which are particularly marked at cortical sites, were kept under control. We reviewed the evidence that intermittent PTH therapy is a valid treatment option ...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2005.11.007

    authors: Thomas T

    更新日期:2006-05-01 00:00:00

  • Sonographic assessment of calcium pyrophosphate deposition disease at wrist. A focus on the dorsal scapho-lunate ligament.

    abstract:OBJECTIVES:To investigate the diagnostic accuracy of ultrasound and conventional radiography in the evaluation of calcium pyrophosphate crystal deposits at wrist level. METHODS:Consecutive patients with a "definite" diagnosis of calcium pyrophosphate deposition disease and disease-controls were prospectively included ...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2020.04.012

    authors: Cipolletta E,Smerilli G,Mashadi Mirza R,Di Matteo A,Carotti M,Salaffi F,Grassi W,Filippucci E

    更新日期:2020-12-01 00:00:00

  • Prospective randomized study comparing the medicoeconomic benefits of Hylan GF-20 vs. conventional treatment in knee osteoarthritis.

    abstract:OBJECTIVES:In a previous study, we determined the costs over 6 months to the French public health insurance system of Hylan GF-20 (Synvisc) in 66 patients with knee osteoarthritis. Here, we compared the medicoeconomic benefits over 9 months in 506 patients given Hylan GF-20 or conventional treatment for knee osteoarthr...

    journal_title:Joint bone spine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s1297-319x(03)00043-5

    authors: Kahan A,Lleu PL,Salin L

    更新日期:2003-08-01 00:00:00

  • Thoracic myelopathy caused by calcified ligamentum flavum.

    abstract::Calcification of the ligamentum flavum is a rare manifestation of the calcium pyrophosphate dihydrate deposition disease (CPPD). In CPPD deposition disease, spinal involvement is rare. Until now, thoracic spine CPPD causing thoracic cord compression has been reported in only sporadic cases. We report a new case of tho...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2007.01.029

    authors: Giulioni M,Zucchelli M,Damiani S

    更新日期:2007-10-01 00:00:00

  • Spontaneous giant expanding thigh hematoma mimicking soft tissue neoplasm.

    abstract::We present a case of giant chronic expanding hematoma occurring in the left lateral thigh without any history of trauma or chronic medical disease. In our case, a diagnosis was unable to perform through conventional diagnosis method, which was confirmed by histopathological examination after successful surgical treatm...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2007.01.041

    authors: Cebesoy O,Tutar E,Arpacioglu O

    更新日期:2008-01-01 00:00:00

  • Assessing damage in individual joints in rheumatoid arthritis: a new method based on the Larsen system.

    abstract:OBJECTIVES:To evaluate observer agreement using the Larsen system (LS) and a Modified Larsen system (ML) when assessing individual joints of the hands and wrists in rheumatoid arthritis, and to compare the two systems. To determine the minimally important difference (MID) for the ML. METHODS:Thirty radiographs of hand...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2003.07.009

    authors: Zangger P,Kachura JR,Bombardier C,Redelmeier DA,Badley EM,Bogoch ER

    更新日期:2004-09-01 00:00:00

  • The effect of periodontal treatment on patients with rheumatoid arthritis: The ESPERA randomised controlled trial.

    abstract:OBJECTIVES:To assess the effect of periodontal treatment on clinical and biochemical parameters of rheumatoid arthritis (RA) and quality of life (QoL) in patients with moderately active RA who were diagnosed with periodontitis. METHODS:In this open-label randomised controlled trial, RA subjects (n = 22) were allocated...

    journal_title:Joint bone spine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jbspin.2019.02.006

    authors: Monsarrat P,Fernandez de Grado G,Constantin A,Willmann C,Nabet C,Sixou M,Cantagrel A,Barnetche T,Mehsen-Cetre N,Schaeverbeke T,Arrivé E,Vergnes JN,ESPERA Group.

    更新日期:2019-10-01 00:00:00

  • Anthropometry at birth as a strong determinant factor of young women bone status: influence of high-level physical activity.

    abstract:OBJECTIVE:To analyze the influence of anthropometry at birth on bone status and physical activity aptitudes of adult women. METHODS:Our population was composed of 70 women (17-29 years): 40 athletes and 30 controls. Athletes participated in various long-lasting and high-level weight-bearing sports (10.2 ± 2.2h ours/we...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2010.07.020

    authors: Bréban S,Chappard C,Jaffré C,Briot K,Benhamou CL

    更新日期:2011-03-01 00:00:00

  • Osteitis pubis after Marshall-Marchetti-Krantz urethropexy.

    abstract::We report a case of osteitis pubis after Marshall-Marchetti-Krantz urethropexy. There are several theories on the pathogenesis of the postoperative osteitis pubis and inconsistent results with a wide variety of treatments. Also, osteomyelitis and osteitis pubis can have identical symptoms. In our case, the use of a Mi...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/s1297-319x(02)00013-1

    authors: Garcia-Porrua C,Picallo JA,Gonzalez-Gay MA

    更新日期:2003-02-01 00:00:00

  • A study on thrombophilic factors in Italian Behcet's patients.

    abstract:BACKGROUND:Behcet's disease (BD) may complicate with arterial and venous thrombosis. The purpose of this work is to evaluate in an Italian group of BD patients with thrombotic events a large panel of inherited and acquired thrombophilic factors. METHODS:Thirty BD patients, of which nine with previously arterial or ven...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2010.02.022

    authors: Caramaschi P,Poli G,Bonora A,Volpe A,Tinazzi I,Pieropan S,Bambara LM,Biasi D

    更新日期:2010-07-01 00:00:00

  • Longitudinal femoral shaft due to bone insufficiency. A review of three cases.

    abstract::We report three new cases of longitudinal femoral shaft fracture due to bone insufficiency and review the eight cases reported in the literature. The typical patient is a woman older than 65 years of age who present with mechanical pain in the thigh and/or groin. Palpation of the thigh may reproduce the pain. The diag...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/s1297-319x(03)00051-4

    authors: Maraval A,Grados F,Royant V,Damade R,Boulu G,Fardellone P

    更新日期:2003-12-01 00:00:00

  • Signal transduction pathways: new targets for treating rheumatoid arthritis.

    abstract::Biotherapies and other new treatments introduced over the last few years have considerably enriched the therapeutic armamentarium for rheumatoid arthritis. Nevertheless, primary refractoriness or secondary escape phenomenon may occur, indicating a need for identifying new treatment targets. Promising candidates can be...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2004.03.004

    authors: Morel J,Berenbaum F

    更新日期:2004-11-01 00:00:00

  • Monosodium urate and calcium pyrophosphate dihydrate (CPPD) crystals, inflammation, and cellular signaling.

    abstract::Monosodium urate (MSU) and calcium pyrophosphate dihydrate (CPPD) crystals are responsible for acute synovial inflammation but also contribute to cartilage degradation and bone lesions within the joint. They activate multiple signal transduction pathways leading to cell activation and recruitment. Some signalling path...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2004.12.010

    authors: Liu-Bryan R,Lioté F

    更新日期:2005-07-01 00:00:00

  • A comparison of three cell types as potential candidates for intervertebral disc therapy: annulus fibrosus cells, chondrocytes, and bone marrow derived cells.

    abstract:OBJECTIVES:Candidate cell types for disc cell transplantation therapy include anulus fibrosus (AF) cells, chondrocytes, and bone marrow derived cells (BMDCs). We compared the disc matrix production in these three types of cells, before and after stimulation with rhBMP-2. There is no study extant that compares these thr...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2008.02.021

    authors: Kuh SU,Zhu Y,Li J,Tsai KJ,Fei Q,Hutton WC,Yoon TS

    更新日期:2009-01-01 00:00:00

  • Anti-neutrophil cytoplasmic antibodies in patients with rheumatoid arthritis: clinical, biological, and radiological correlations.

    abstract:OBJECTIVES:To determine the prevalence and the associations of anti-neutrophil cytoplasmic antibodies (ANCA) and subtypes with clinical, biological, and radiological findings in patients with rheumatoid arthritis (RA). MATERIALS AND METHODS:This is a transversal study of 85 patients with RA (followed in Ibn-i Sina Hos...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2003.04.002

    authors: Tur BS,Süldür N,Ataman S,Tutkak H,Atay MB,Düzgün N

    更新日期:2004-05-01 00:00:00

  • Acromegaly is associated with vertebral deformations but not vertebral fractures: Results of a cross-sectional monocentric study.

    abstract:OBJECTIVES:Patients with acromegaly appear to be at increased risk of vertebral fractures despite normal bone mineral density. We investigated the prevalence of vertebral fractures in a cohort of acromegalic patients under 80 years of age. METHODS:Monocentric cross-sectional study performed at Nantes University Hospit...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2020.04.020

    authors: Plard C,Hochman C,Hadjadj S,Le Goff B,Maugars Y,Cariou B,Drui D,Guillot P

    更新日期:2020-12-01 00:00:00

  • Predictors of mortality in rheumatoid arthritis-associated lung disease: Monocentric experience of ten-years.

    abstract:OBJECTIVES:Rheumatoid arthritis (RA)-associated lung involvement is a cause of mortality. This study aimed to evaluate mortality rate and mortality-associated factors in RA patients with high-resolution computed tomography (HRCT)-proven lung involvement. METHODS:Patients followed-up for RA between 2010 and 2018 were e...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2021.105133

    authors: Ekici M,Baytar Y,Kardas RC,Sari A,Akdogan A,Durhan G,Ariyurek M,Kalyoncu U

    更新日期:2021-01-20 00:00:00

  • Schnitzler syndrome.

    abstract::Schnitzler syndrome is characterized by monoclonal IgM gammopathy, urticaria, recurrent fever, evidence of inflammation, bone pain, and arthralgia, occasionally in combination with lymphadenopathy and/or hepatosplenomegaly. Only about 80 cases have been reported to date. Development of a hematological malignancy is th...

    journal_title:Joint bone spine

    pub_type: 杂志文章,评审

    doi:10.1016/j.jbspin.2007.07.014

    authors: Soubrier M

    更新日期:2008-05-01 00:00:00

  • An unusual presentation of primary hyperparathyroidism: severe hypercalcemia and multiple brown tumors.

    abstract::Primary hyperparathyroidism is common, particularly in postmenopausal women. Since the introduction of routine automated serum calcium assays and the development of assays for intact 1-84 parathyroid hormone, the diagnosis is usually made fortuitously in asymptomatic patients or during evaluation for osteoporosis. As ...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2007.03.004

    authors: Jouan A,Zabraniecki L,Vincent V,Poix E,Fournié B

    更新日期:2008-03-01 00:00:00

  • Anti -citrullinated peptide antibodies profiling in established rheumatoid arthritis.

    abstract:OBJECTIVES:Anti-citrullinated protein/peptide antibodies (ACPA) represent an important tool for the diagnosis of rheumatoid arthritis (RA) and the presence of multiple ACPA specificities is highly correlated with the evolution towards RA. However, little is known about the association of single specificities with disea...

    journal_title:Joint bone spine

    pub_type: 杂志文章

    doi:10.1016/j.jbspin.2017.07.009

    authors: Manca ML,Alunno A,D'Amato C,Bistoni O,Puxeddu I,Gerli R,Migliorini P,Pratesi F

    更新日期:2018-07-01 00:00:00