Triptans: where things stand.

abstract：:Neuromyelitis optica (NMO, Devic's syndrome) is characterized by concurrence of optic neuritis and transverse myelitis, typically associated with a lesion in the spinal cord extending over three or more vertebral segments. It is an inflammatory, demyelinating central nervous system disorder, and although it is most co...

journal_title：Current treatment options in neurology

authors： Wingerchuk DM,Weinshenker BG

更新日期：2008-01-01 00:00:00

abstract：:Apathy is a common problem observed in numerous neurologic, psychiatric, and other medical conditions. It is independent from other symptoms and has been associated with a variety of negative outcomes. However, little empirical research has been conducted on potential psychologic or pharmacologic treatments for apathy...

journal_title：Current treatment options in neurology

authors： Roth RM,Flashman LA,McAllister TW

更新日期：2007-09-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease that usually results in death secondary to respiratory failure. The psychological reaction to the diagnosis of ALS in patient and caregiver has received increasing attention. Reports are highly variable as to the severity of depressive symptoms ...

journal_title：Current treatment options in neurology

authors： Stromberg SF,Weiss DB

更新日期：2006-09-01 00:00:00

abstract：Purpose of Review:Giant cell arteritis (GCA), a medium and large vessel vasculitis occurring in the aged, remains a formidable disease, capable of taking both vision and life, through a multitude of vascular complications. Our understanding of the spectrum of its manifestations has grown over the years, to include limb...

journal_title：Current treatment options in neurology

authors： Dinkin M,Johnson E

更新日期：2021-01-01 00:00:00

abstract：:Although estimates vary, the nervous system appears to be involved in 10% to 15% of patients infected with Borrelia burgdorferi. The resulting disorders, known collectively as neuroborreliosis or nervous system Lyme disease, generally respond well to antimicrobial therapy. Definitive treatment of nervous system infect...

journal_title：Current treatment options in neurology

authors： Halperin JJ

更新日期：2007-03-01 00:00:00

abstract：:Dystonia is a neurologic disorder that can occur at any age and often results in significant disability. The therapeutic application of botulinum toxin has revolutionized the treatment of this disorder, particularly for the adult-onset focal forms such as cervical dystonia and blepharospasm. The two available commerci...

journal_title：Current treatment options in neurology

authors： Cardona-Garcia OD,Higgins DS,Molho ES

更新日期：2007-05-01 00:00:00

abstract：:Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by degeneration of spinal cord motor neurons and muscular atrophy. Advances in recent research have led to understanding of the molecular genetics of SMA. Therapeutic strategies have been developed according to the unique genomic structure o...

journal_title：Current treatment options in neurology

authors： Wang CH,Lunn MR

更新日期：2008-11-01 00:00:00

abstract：OPINION STATEMENT:Infantile spasms (IS) represent a major therapeutic challenge, as cessation of spasms and normalization of the electroencephalogram (elimination of hypsarrhythmia) are mandatory to prevent cognitive deterioration in previously healthy infants, or to preserve neurocognitive function among those neurolo...

journal_title：Current treatment options in neurology

authors： Watemberg N

更新日期：2012-08-01 00:00:00

abstract：OPINION STATEMENT:The diagnosis and appropriate treatment of hyperkinetic movement disorders require a work up of potentially reversible metabolic, infectious and structural disorders as well as side effects of current medication. In pharmacoresistant movement disorders with a disabling impact on quality of life, deep ...

journal_title：Current treatment options in neurology

authors： Barbey A,Bloch J,Vingerhoets FJ

更新日期：2015-09-01 00:00:00

abstract：Purpose of review:The purpose of this paper is to comprehensively evaluate secondary causes of inflammatory myopathies (myositis) and to review treatment options. Recent findings:This review highlights recent advancements in our understanding of known causes of myositis, including newer drugs that may cause myositis s...

journal_title：Current treatment options in neurology

authors： Berth SH,Lloyd TE

更新日期：2020-01-01 00:00:00

abstract：OPINION STATEMENT:A patient presenting with suspected primary central nervous system (CNS) vasculitis is often difficult to manage. Once the diagnosis is suspected, the clinical course may already be severe and warrant timely aggressive treatment with potentially toxic drugs. Definitive diagnosis is often delayed, requ...

journal_title：Current treatment options in neurology

authors： Gotkine M,Vaknin-Dembinsky A

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Children surviving the pediatric intensive care unit (PICU) with neurologic illness or injury have long-term morbidities in physical, cognitive, emotional, and social functioning termed postintensive care syndrome (PICS). In this article, we review acute and longitudinal management strategies availabl...

journal_title：Current treatment options in neurology

authors： Williams CN,Hartman ME,Guilliams KP,Guerriero RM,Piantino JA,Bosworth CC,Leonard SS,Bradbury K,Wagner A,Hall TA

更新日期：2019-09-27 00:00:00

abstract：:Progressive supranuclear palsy (PSP) is an atypical parkinsonian disorder that, in spite of its growing recognition, is still underdiagnosed. For management, prognosis, and research, an accurate and early diagnosis is essential. PSP is a relentlessly progressive neurodegenerative disorder, clinically characterized by ...

journal_title：Current treatment options in neurology

authors： van Balken I,Litvan I

更新日期：2006-05-01 00:00:00

abstract：:Antiepileptic drug (AED) treatment is associated with multiple short- and long-term side effects. Effects on endocrine function, including weight change, reproductive function, thyroid function, and bone health are examples of these side effects. Some AEDs affect weight, resulting in weight gain or loss. Levetiracetam...

journal_title：Current treatment options in neurology

authors： Pack A

更新日期：2005-07-01 00:00:00

abstract：OPINION STATEMENT:The aims of this article are to discuss the potential role of B lymphocytes in the pathogenesis of multiple sclerosis (MS) and in the mechanisms of action of approved and emerging disease modifying therapies. Over the last few years, significant progress has been made in the introduction of novel phar...

journal_title：Current treatment options in neurology

authors： Braley TJ,Segal BM

更新日期：2013-06-01 00:00:00

abstract：OPINION STATEMENT:Magnetic resonance imaging (MRI) is the gold standard guiding diagnostic and therapeutic management in glioma with its high resolution and possibility to depict blood-brain-barrier disruption when contrast medium is applied. In light of the shifting paradigms revealing distinct tumor subtypes based on...

journal_title：Current treatment options in neurology

authors： Suchorska B,Albert NL,Tonn JC

更新日期：2016-01-01 00:00:00

abstract：:All patients who present with subarachnoid hemorrhage should be admitted to the intensive care unit for close neurologic and cardiorespiratory monitoring. Neurosurgical consultation should be obtained if external ventricular drain placement, arteriography, or surgical planning are considered. Seizure prophylaxis, anti...

journal_title：Current treatment options in neurology

authors： Flemming KD,Brown RD Jr,Wiebers DO

更新日期：1999-05-01 00:00:00

abstract：OPINION STATEMENT:When treating a person with epilepsy, one must consider many factors in addition to the obvious need to treat the seizures. Both epilepsy itself and treatment with antiepileptic drugs (AEDs) subject one to numerous potential secondary long-term health concerns. Poor bone health is one of these concern...

journal_title：Current treatment options in neurology

authors： Pack AM

更新日期：2011-08-01 00:00:00

abstract：:There is no standard therapy for acute disseminated encephalomyelitis (ADEM), and treatments are based on the analogy of the pathogenesis of ADEM with that of multiple sclerosis (MS), namely an inflammatory perivenular demyelination. High-dose intravenous corticosteroids, such as methylprednisolone, at a dosage standa...

journal_title：Current treatment options in neurology

authors： Tselis A

更新日期：2001-11-01 00:00:00

abstract：:Drug-induced parkinsonism (DIP) is condition that mimics Parkinson's disease. Characterized mainly by rigidity and bradykinesia, it has less prominent tremor and gait instability. DIP is generally caused by lipophilic drugs that "block" dopamine D2 receptors in the brain, although presynaptic dopamine depletion, false...

journal_title：Current treatment options in neurology

authors： Susatia F,Fernandez HH

更新日期：2009-05-01 00:00:00

abstract：:The elderly are the most rapidly growing segment of the population, and the incidence of epilepsy in persons over 65 is higher than in any other age group. In nursing homes, its incidence is even higher than in community-dwelling persons of similar ages. About 10% of nursing home residents are being treated with antie...

journal_title：Current treatment options in neurology

authors： Leppik IE

更新日期：2008-07-01 00:00:00

abstract：OPINION STATEMENT:The purpose of this review is to provide an overview of visual snow (VS) and provide information regarding current treatment options for VS. Visual snow (VS) is a rare disorder manifesting with a persistent visual phenomenon of seeing numerous tiny snow-like dots throughout the visual field, and it ca...

journal_title：Current treatment options in neurology

authors： Bou Ghannam A,Pelak VS

更新日期：2017-03-01 00:00:00

abstract：OPINION STATEMENT:Autoimmune neuromuscular disorders in childhood include Guillain-Barré syndrome and its variants, chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), juvenile myasthenia gravis (JMG), and juvenile dermatomyositis (JDM), along with other disorders rarely seen in childhood. In general, the...

journal_title：Current treatment options in neurology

authors： McMillan HJ,Darras BT,Kang PB

更新日期：2011-12-01 00:00:00

abstract：:Vagus nerve stimulation is a unique therapy for epileptic seizures. Two randomized controlled trials in patients with medically refractory partial seizures have demonstrated efficacy, leading to US Food and Drug Administration approval of vagus nerve stimulation therapy in 1997. Extensive safety testing has not reveal...

journal_title：Current treatment options in neurology

authors： Salinsky MC

更新日期：2003-03-01 00:00:00

abstract：OPINION STATEMENT:The timely implementation of immunotherapy is key to successful treatment of autoimmune encephalopathies or dementias (from here on will be referred to as autoimmune encephalopathies). There are different levels of diagnostic certainty which should guide the immunological treatment of autoimmune encep...

journal_title：Current treatment options in neurology

authors： McKeon A

更新日期：2013-12-01 00:00:00

abstract：:Transplantation of bone marrow or peripheral blood stem cells is increasingly being used to treat a variety of oncologic disorders. These procedures are associated with a large spectrum of neurologic complications that significantly contribute to patient morbidity and mortality. These complications may arise at any ti...

journal_title：Current treatment options in neurology

authors： Mathew RM,Rosenfeld MR

更新日期：2007-07-01 00:00:00

abstract：:Autistic spectrum disorders (ASD) are an often-disabling continuum of disorders affecting two to four in 1000 children. These disorders have a core set of defining features including impaired verbal and nonverbal communication, impaired social interaction, and restricted or repetitive patterns of behavior. The cause o...

journal_title：Current treatment options in neurology

authors： Pinto-Martin J,Levy SE

更新日期：2004-09-01 00:00:00

abstract：OPINION STATEMENT:Atrial fibrillation (AF) is the most common sustained cardiac rhythm disorder, which can potentially increases the risk of stroke by five-fold, thus, resulting in high public healthcare burden. Stroke prevention is vital in the management of AF patients. Vitamin K antagonists (VKA, eg, warfarin) have ...

journal_title：Current treatment options in neurology

authors： Xiong Q,Lip GY

更新日期：2015-02-01 00:00:00

abstract：:The initial treatment for trigeminal neuralgia is medical. Carbamazepine is the drug of choice. If the patient proves to be intolerant of carbamazepine, a number of second-line drugs are available, though data on their relative efficacy are nonexistent. Phenytoin, baclofen, clonazepam, and sodium valproate are all wor...

journal_title：Current treatment options in neurology

authors： Perkin GD

更新日期：1999-11-01 00:00:00

abstract：:Patients with functional or nonorganic visual disturbances are often seen in general ophthalmology practice and then referred to neurology and/or neuro-ophthalmology. The diagnosis of functional vision loss requires comprehensive examinations and diagnostic testing to eliminate possible organic entities. Inconsistenci...

journal_title：Current treatment options in neurology

authors： Leavitt JA

更新日期：2006-01-01 00:00:00