Treatment of epilepsy in the elderly.

abstract：OPINION STATEMENT:Narcolepsy is a severe, incurable, neurological disorder that is treated by pharmacological management of its symptoms. The main symptoms are excessive daytime sleepiness (EDS) and cataplexy, although addition symptoms that may require treatment include sleep paralysis, hypnagogic hallucinations, and ...

journal_title：Current treatment options in neurology

authors： Thorpy MJ

更新日期：2015-05-01 00:00:00

abstract：OPINION STATEMENT:Restless legs syndrome (RLS) is a common, sensorimotor, circadian sleep disorder characterized by the urge to move the legs, particularly at nighttime. It is important to differentiate primary and secondary RLS from other conditions, which can mimic the symptoms of RLS, in particular neuropathy and cr...

journal_title：Current treatment options in neurology

authors： Rios Romenets S,Postuma RB

更新日期：2013-08-01 00:00:00

abstract：:All patients who present with subarachnoid hemorrhage should be admitted to the intensive care unit for close neurologic and cardiorespiratory monitoring. Neurosurgical consultation should be obtained if external ventricular drain placement, arteriography, or surgical planning are considered. Seizure prophylaxis, anti...

journal_title：Current treatment options in neurology

authors： Flemming KD,Brown RD Jr,Wiebers DO

更新日期：1999-05-01 00:00:00

abstract：:Standard therapy does not exist for the treatment of primary central nervous system lymphoma. This is because of low patient numbers, slow accrual to clinical trials, and the absence of phase III randomized clinical trials. Neuro-oncologists agree that whole brain irradiation alone is no longer the best treatment opti...

journal_title：Current treatment options in neurology

authors： Damek DM

更新日期：2003-05-01 00:00:00

abstract：OPINION STATEMENT:Magnetic resonance imaging (MRI) is the gold standard guiding diagnostic and therapeutic management in glioma with its high resolution and possibility to depict blood-brain-barrier disruption when contrast medium is applied. In light of the shifting paradigms revealing distinct tumor subtypes based on...

journal_title：Current treatment options in neurology

authors： Suchorska B,Albert NL,Tonn JC

更新日期：2016-01-01 00:00:00

abstract：OPINION STATEMENT:The recognition of the diagnosis of migraine in the pediatric population is increasing. Early and aggressive treatment of migraine in children and adolescents with the use of over-the-counter medications has proven effective. In addition, the off-label use of many migraine-specific medications is ofte...

journal_title：Current treatment options in neurology

authors： O'Brien HL,Kabbouche MA,Hershey AD

更新日期：2010-05-01 00:00:00

abstract：:The neurorehabilitation program for cerebral palsy changes over time. During the first 2 years of life, an infant stimulation program with an emphasis on more than just improving motor deficits is emphasized. The importance of involvement of a knowledgeable therapist cannot be overemphasized. Realistic expectations mu...

journal_title：Current treatment options in neurology

authors： Russman BS

更新日期：2000-03-01 00:00:00

abstract：OPINION STATEMENT:Neurofibromatosis type 1 (NF1) is a genetic multisystemic disorder involving the skin, the central and peripheral nervous systems, bones, and the cardiovascular and endocrine systems. This condition is caused by inherited or de novo mutations of the NF1 gene at the 17q11.2 chromosomal region, a gene t...

journal_title：Current treatment options in neurology

authors： Sabatini C,Milani D,Menni F,Tadini G,Esposito S

更新日期：2015-06-01 00:00:00

abstract：:Allodynia is a normal part of the untreated migraine attack in most people with episodic migraine and is prevalent in chronic migraine. The extent to which allo-dynia contributes to the pain and disability of migraine attacks is unclear, as is its clinical importance. The presence of allodynia correlates with the seve...

journal_title：Current treatment options in neurology

authors： Young WB

更新日期：2009-01-01 00:00:00

abstract：:Medical management, the mainstay of treatment for partial epilepsy, involves choosing from an array of antiseizure drugs, most of which have comparable efficacy against partial-onset seizures. Effective treatment strategies involve matching the characteristics of drug and patient to control seizures without adverse ef...

journal_title：Current treatment options in neurology

authors： Liu L,Henry JC

更新日期：2009-07-01 00:00:00

abstract：:The challenge for the neurologist in the treatment of Lyme neuroborreliosis is not in the treatment per se, but in the diagnosis. Neurological manifestations of Lyme disease can present in many forms, and diagnostic techniques which detect the spirochete directly; the culture or polymerase chain reaction of the spiroc...

journal_title：Current treatment options in neurology

authors： Pachner AR

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will examine the current evidence that genetic and/or epigenetic variation may influence the multiple sclerosis (MS) clinical course, phenotype, and measures of MS severity including disability progression and relapse rate. RECENT FINDINGS:There is little evidence that MS clinical phenoty...

journal_title：Current treatment options in neurology

authors： Jokubaitis VG,Zhou Y,Butzkueven H,Taylor BV

更新日期：2018-04-24 00:00:00

abstract：PURPOSE OF REVIEW:Children surviving the pediatric intensive care unit (PICU) with neurologic illness or injury have long-term morbidities in physical, cognitive, emotional, and social functioning termed postintensive care syndrome (PICS). In this article, we review acute and longitudinal management strategies availabl...

journal_title：Current treatment options in neurology

authors： Williams CN,Hartman ME,Guilliams KP,Guerriero RM,Piantino JA,Bosworth CC,Leonard SS,Bradbury K,Wagner A,Hall TA

更新日期：2019-09-27 00:00:00

abstract：OPINION STATEMENT:Autoimmune neuromuscular disorders in childhood include Guillain-Barré syndrome and its variants, chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), juvenile myasthenia gravis (JMG), and juvenile dermatomyositis (JDM), along with other disorders rarely seen in childhood. In general, the...

journal_title：Current treatment options in neurology

authors： McMillan HJ,Darras BT,Kang PB

更新日期：2011-12-01 00:00:00

abstract：OPINION STATEMENT:The treatment of anaplastic glioma (AG) varies depending on histopathology of the tumor, molecular markers, and individual patient characteristics. Maximal surgical resection is desirable for all types of AG if technically feasible, with an acceptable level of risk, and with the goal of preserving neu...

journal_title：Current treatment options in neurology

authors： Paleologos NA,Merrell RT

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Idiopathic normal pressure hydrocephalus (iNPH) is a surgically treatable neurological disorder of the elderly population that is characterized by abnormal ventricular enlargement due to cerebrospinal fluid (CSF) accumulation and gait disturbance, cognitive impairment, or urinary incontinence. The obj...

journal_title：Current treatment options in neurology

authors： Isaacs AM,Williams MA,Hamilton MG

更新日期：2019-12-03 00:00:00

abstract：:Dystonia is a neurologic disorder that can occur at any age and often results in significant disability. The therapeutic application of botulinum toxin has revolutionized the treatment of this disorder, particularly for the adult-onset focal forms such as cervical dystonia and blepharospasm. The two available commerci...

journal_title：Current treatment options in neurology

authors： Cardona-Garcia OD,Higgins DS,Molho ES

更新日期：2007-05-01 00:00:00

abstract：OPINION STATEMENT:Use of cannabinoids as medications has a long history. Unfortunately, the prohibition of cannabis and its classification in 1970 as a schedule 1 drug has been a major obstacle in studying these agents in a systematic, controlled manner. The number of class 1 studies (randomized, double-blind, placebo-...

journal_title：Current treatment options in neurology

authors： Catlow B,Sanchez-Ramos J

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Sleep-related movement disorders (SRMD) include several different motor activities during sleep. Few of them are well known and well classified, whereas others are minor motor disorders of sleep which are neither thoroughly characterized and classified nor have been extensively investigated to clarify...

journal_title：Current treatment options in neurology

authors： Stefani A,Högl B

更新日期：2019-01-19 00:00:00

abstract：:Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by degeneration of spinal cord motor neurons and muscular atrophy. Advances in recent research have led to understanding of the molecular genetics of SMA. Therapeutic strategies have been developed according to the unique genomic structure o...

journal_title：Current treatment options in neurology

authors： Wang CH,Lunn MR

更新日期：2008-11-01 00:00:00

abstract：OPINION STATEMENT:CADASIL is a life-threatening and disabling disease. Despite the progress achieved so far, no therapies able to limit the disease progression have been found and only empiric treatments can be employed to relieve the main disease symptoms. Further in vivo studies as well as data aggregation and multi-...

journal_title：Current treatment options in neurology

authors： Bersano A,Bedini G,Oskam J,Mariotti C,Taroni F,Baratta S,Parati EA

更新日期：2017-09-01 00:00:00

abstract：:The treatment of progressive myoclonus epilepsy (PME) remains a major therapeutic challenge in neurology. Generalized convulsive seizures are often well controlled through classic antiepileptic drugs (AEDs) like valproate and clonazepam, whereas myoclonus, the main symptom that is affecting patients most in their dail...

journal_title：Current treatment options in neurology

authors： Uthman BM,Reichl A

更新日期：2002-01-01 00:00:00

abstract：:Antiepileptic drug (AED) treatment is associated with multiple short- and long-term side effects. Effects on endocrine function, including weight change, reproductive function, thyroid function, and bone health are examples of these side effects. Some AEDs affect weight, resulting in weight gain or loss. Levetiracetam...

journal_title：Current treatment options in neurology

authors： Pack A

更新日期：2005-07-01 00:00:00

abstract：OPINION STATEMENT:High-grade or malignant gliomas are aggressive cancers. The World Health Organization (WHO) grading system recognizes grade III and grade IV primary brain tumors of astrocytic, oligodendroglial, or mixed lineage. Identification of these tumors is prompted by symptoms such as insidious headaches, seizu...

journal_title：Current treatment options in neurology

authors： Giglio P,Villano JL

更新日期：2010-07-01 00:00:00

abstract：:Herpes simplex virus (HSV) infections are ubiquitous. Children are infected with HSV resulting in totally asymptomatic acquisition to life-threatening disease. Therapy of HSV diseases of children can be considered according to severity and time of acquisition. Neonatal herpes simplex virus infections take one of three...

journal_title：Current treatment options in neurology

authors： Whitley RJ

更新日期：2002-05-01 00:00:00

abstract：:Subdural empyema represents loculated infection between the outermost layer of the meninges, the dura, and the arachnoid. The empyema may develop intracranially or in the spinal canal. Intracranial subdural empyema is most frequently a complication of sinusitis or, less frequently, otitis or neurosurgical procedures. ...

journal_title：Current treatment options in neurology

authors： Greenlee JE

更新日期：2003-01-01 00:00:00

abstract：:Spontaneous intracerebral hemorrhage (ICH) is a devastating neurological event with a 30-day mortality of approximately 40%. Recent research provides new insights into the pathophysiology of ICH-associated edema, with potential molecular and cellular targets for future therapy. Neuroimaging techniques such as gradient...

journal_title：Current treatment options in neurology

authors： Freeman WD,Brott TG

更新日期：2006-03-01 00:00:00

abstract：:There is no standard therapy for acute disseminated encephalomyelitis (ADEM), and treatments are based on the analogy of the pathogenesis of ADEM with that of multiple sclerosis (MS), namely an inflammatory perivenular demyelination. High-dose intravenous corticosteroids, such as methylprednisolone, at a dosage standa...

journal_title：Current treatment options in neurology

authors： Tselis A

更新日期：2001-11-01 00:00:00

abstract：:Despite increasing recognition of childhood obstructive sleep apnea syndrome (OSAS) as a significant public health problem, treatment of the condition remains inconsistent. Some children are screened using polysomnography and treated only when objective respiratory disturbances are identified. Many others receive aden...

journal_title：Current treatment options in neurology

authors： Hoban TF

更新日期：2005-09-01 00:00:00

abstract：OPINION STATEMENT:To date, there are no approved and established pharmacologic treatment options for tauopathies, a very heterogenous group of neuropsychiatric diseases often leading to dementia and clinically diagnosed as atypical Parkinson syndromes. Among these so-called Parkinson plus syndromes are progressive supr...

journal_title：Current treatment options in neurology

authors： Karakaya T,Fußer F,Prvulovic D,Hampel H

更新日期：2012-04-01 00:00:00