Update on therapy for narcolepsy.

abstract：PURPOSE OF REVIEW:This review will examine the current evidence that genetic and/or epigenetic variation may influence the multiple sclerosis (MS) clinical course, phenotype, and measures of MS severity including disability progression and relapse rate. RECENT FINDINGS:There is little evidence that MS clinical phenoty...

journal_title：Current treatment options in neurology

authors： Jokubaitis VG,Zhou Y,Butzkueven H,Taylor BV

更新日期：2018-04-24 00:00:00

abstract：:Given our current knowledge, there is a need for the early institution of immunomodulatory therapy, especially for patients with poor prognostic factors (motor and cerebellar symptoms, frequent disease exacerbations, and a high level of activity on magnetic resonance imaging ). Patients who progress despite immunomodu...

journal_title：Current treatment options in neurology

authors： Bielekova B,Martin R

更新日期：1999-07-01 00:00:00

abstract：OPINION STATEMENT:Paraneoplastic brain stem encephalitis can occur as an isolated clinical syndrome or, more often, may be part of a more widespread encephalitis. Different antineuronal autoantibodies, such as anti-Hu, anti-Ri, and anti-Ma2 can be associated with the syndrome, and the most frequent tumors are lung and ...

journal_title：Current treatment options in neurology

authors： Blaes F

更新日期：2013-04-01 00:00:00

abstract：:Sleep disorders can have a significant impact on the growth and development of children. Behavioral intervention is the first step in the management of many sleep disorders. Limit-setting is particularly challenging in younger children but must be consistent. Good sleep hygiene practices must be emphasized to adolesce...

journal_title：Current treatment options in neurology

authors： Lam JC,Mason TB

更新日期：2007-11-01 00:00:00

abstract：OPINION STATEMENT:Impaired sleep and alertness affect the majority of Parkinson's disease (PD) patients, negatively impacting safety and quality of life. The etiology of impaired sleep-wake cycle in PD is multifactorial and encompasses medication side effects, nocturnal PD motor symptoms, and presence of co-existent sl...

journal_title：Current treatment options in neurology

authors： Amara AW,Chahine LM,Videnovic A

更新日期：2017-07-01 00:00:00

abstract：OPINION STATEMENT:The purpose of this review is to provide an overview of visual snow (VS) and provide information regarding current treatment options for VS. Visual snow (VS) is a rare disorder manifesting with a persistent visual phenomenon of seeing numerous tiny snow-like dots throughout the visual field, and it ca...

journal_title：Current treatment options in neurology

authors： Bou Ghannam A,Pelak VS

更新日期：2017-03-01 00:00:00

abstract：:Drug-induced parkinsonism (DIP) is condition that mimics Parkinson's disease. Characterized mainly by rigidity and bradykinesia, it has less prominent tremor and gait instability. DIP is generally caused by lipophilic drugs that "block" dopamine D2 receptors in the brain, although presynaptic dopamine depletion, false...

journal_title：Current treatment options in neurology

authors： Susatia F,Fernandez HH

更新日期：2009-05-01 00:00:00

abstract：:All patients who present with subarachnoid hemorrhage should be admitted to the intensive care unit for close neurologic and cardiorespiratory monitoring. Neurosurgical consultation should be obtained if external ventricular drain placement, arteriography, or surgical planning are considered. Seizure prophylaxis, anti...

journal_title：Current treatment options in neurology

authors： Flemming KD,Brown RD Jr,Wiebers DO

更新日期：1999-05-01 00:00:00

abstract：OPINION STATEMENT:The problem of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA) management remains unsolved. Despite a myriad of therapeutic trials, no convincingly e...

journal_title：Current treatment options in neurology

authors： Pareja JA,Alvarez M,Montojo T

更新日期：2013-02-01 00:00:00

abstract：:Cysticercosis, the consequence of ingesting viable eggs of the porcine tapeworm Taenia solium, currently remains one of the most common human parasitic conditions worldwide. Although preventable by the proper disposal of human wastes, cysticercosis of the central nervous system (neurocysticercosis) accounts for a subs...

journal_title：Current treatment options in neurology

authors： Bale JF Jr

更新日期：2000-07-01 00:00:00

abstract：:Classic maple syrup disease can be managed to allow a benign neonatal course, normal growth, and low hospitalization rates. The majority of affected infants that are prospectively managed have good neurodevelopmental outcome; however, acute metabolic intoxication and neurologic deterioration can develop rapidly at any...

journal_title：Current treatment options in neurology

authors： Strauss KA,Morton DH

更新日期：2003-07-01 00:00:00

abstract：OPINION STATEMENT:Restless Legs Syndrome/Willis-Ekbom Disease (RLS/WED) is a common condition characterized by an irresistible urge to move the legs, concomitant with an unpleasant sensation in the lower limbs, which is typically relieved by movement. Symptoms occur predominantly at rest and prevail in the afternoon or...

journal_title：Current treatment options in neurology

authors： Rinaldi F,Galbiati A,Marelli S,Ferini Strambi L,Zucconi M

更新日期：2016-02-01 00:00:00

abstract：:There has been a recent resurgence of interest in therapeutic modalities using transcranial weak electrical stimulation through scalp electrodes, such as trans-cranial direct current stimulation (tDCS), as a means of experimentally modifying and studying brain function and possibly treating psychiatric conditions. A r...

journal_title：Current treatment options in neurology

authors： Bikson M,Bulow P,Stiller JW,Datta A,Battaglia F,Karnup SV,Postolache TT

更新日期：2008-09-01 00:00:00

abstract：:Dystonia is a neurologic disorder that can occur at any age and often results in significant disability. The therapeutic application of botulinum toxin has revolutionized the treatment of this disorder, particularly for the adult-onset focal forms such as cervical dystonia and blepharospasm. The two available commerci...

journal_title：Current treatment options in neurology

authors： Cardona-Garcia OD,Higgins DS,Molho ES

更新日期：2007-05-01 00:00:00

abstract：:Multiple pharmacologic treatments have been studied, but propranolol and primidone have proven to be the most effective medications. It is unlikely that a patient will respond miraculously to another medication if his or her response to propranolol and primidone is minimal. Some subsets of essential tremor, however, s...

journal_title：Current treatment options in neurology

authors： Lambert D,Waters CH

更新日期：1999-03-01 00:00:00

abstract：:Subdural empyema represents loculated infection between the outermost layer of the meninges, the dura, and the arachnoid. The empyema may develop intracranially or in the spinal canal. Intracranial subdural empyema is most frequently a complication of sinusitis or, less frequently, otitis or neurosurgical procedures. ...

journal_title：Current treatment options in neurology

authors： Greenlee JE

更新日期：2003-01-01 00:00:00

abstract：:The primary goal of treatment in nonepileptic seizures (NES) is to improve the patient's quality of life by terminating seizure production or reducing seizure frequency. Initial treatment consists of explaining the diagnosis and its psychological nature to patients without judging them or giving the NES excessive atte...

journal_title：Current treatment options in neurology

authors： Bowman ES

更新日期：2000-11-01 00:00:00

abstract：:Hemifacial spasm (HFS) is a peripheral movement disorder caused by direct or indirect compression or distortion of the root exit zone of the seventh cranial nerve, which is most commonly compressed by an arterial loop, but also may be compressed by a tumor, cyst, or aneurysm. All patients with HFS should undergo magne...

journal_title：Current treatment options in neurology

authors： Kemp LW,Reich SG

更新日期：2004-05-01 00:00:00

abstract：OPINION STATEMENT:Pervasive developmental disorders (PDDs), including autistic disorder (autism), Asperger's disorder, and pervasive developmental disorder not otherwise specified (PDD NOS), are neurodevelopmental disorders of childhood onset. These disorders persist throughout the lifespan of affected individuals and ...

journal_title：Current treatment options in neurology

authors： Wink LK,Erickson CA,McDougle CJ

更新日期：2010-11-01 00:00:00

abstract：:The epidemiologic link between increased low-density-lipoprotein (LDL) cholesterol and ischemic stroke is controversial. However, recent trials make it clear that LDL reduction by statin agents in high-risk patients reduces the risk of ischemic stroke. The risk of first stroke is reduced within 1 to 2 years of statin ...

journal_title：Current treatment options in neurology

authors： Bernstein RA

更新日期：2006-11-01 00:00:00

abstract：:Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by degeneration of spinal cord motor neurons and muscular atrophy. Advances in recent research have led to understanding of the molecular genetics of SMA. Therapeutic strategies have been developed according to the unique genomic structure o...

journal_title：Current treatment options in neurology

authors： Wang CH,Lunn MR

更新日期：2008-11-01 00:00:00

abstract：OPINION STATEMENT:The timely implementation of immunotherapy is key to successful treatment of autoimmune encephalopathies or dementias (from here on will be referred to as autoimmune encephalopathies). There are different levels of diagnostic certainty which should guide the immunological treatment of autoimmune encep...

journal_title：Current treatment options in neurology

authors： McKeon A

更新日期：2013-12-01 00:00:00

abstract：:Standard therapy does not exist for the treatment of primary central nervous system lymphoma. This is because of low patient numbers, slow accrual to clinical trials, and the absence of phase III randomized clinical trials. Neuro-oncologists agree that whole brain irradiation alone is no longer the best treatment opti...

journal_title：Current treatment options in neurology

authors： Damek DM

更新日期：2003-05-01 00:00:00

abstract：OPINION STATEMENT:The management of herpes zoster (HZ) usually involves a multidisciplinary approach aiming to reduce complications and morbidity. Patients with herpes zoster ophthalmicus (HZO) are referred to ophthalmologists for prevention or treatment of its potential complications. Without prompt detection and trea...

journal_title：Current treatment options in neurology

authors： Sanjay S,Huang P,Lavanya R

更新日期：2011-02-01 00:00:00

abstract：OPINION STATEMENT:The treatment of anaplastic glioma (AG) varies depending on histopathology of the tumor, molecular markers, and individual patient characteristics. Maximal surgical resection is desirable for all types of AG if technically feasible, with an acceptable level of risk, and with the goal of preserving neu...

journal_title：Current treatment options in neurology

authors： Paleologos NA,Merrell RT

更新日期：2012-08-01 00:00:00

abstract：:Transplantation of bone marrow or peripheral blood stem cells is increasingly being used to treat a variety of oncologic disorders. These procedures are associated with a large spectrum of neurologic complications that significantly contribute to patient morbidity and mortality. These complications may arise at any ti...

journal_title：Current treatment options in neurology

authors： Mathew RM,Rosenfeld MR

更新日期：2007-07-01 00:00:00

abstract：:Meningiomas are extra-axial brain tumors of middle-to-late adult life and show a predominance in women. Overall, 90% of meningiomas are benign, 6% atypical, and 2% are malignant. Most patients diagnosed with a meningioma decide to have it removed surgically, and are advised to do so based on their neurologic symptoms....

journal_title：Current treatment options in neurology

authors： Chamberlain MC

更新日期：2001-01-01 00:00:00

abstract：OPINION STATEMENT:Restless legs syndrome (RLS) is a common, sensorimotor, circadian sleep disorder characterized by the urge to move the legs, particularly at nighttime. It is important to differentiate primary and secondary RLS from other conditions, which can mimic the symptoms of RLS, in particular neuropathy and cr...

journal_title：Current treatment options in neurology

authors： Rios Romenets S,Postuma RB

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the current evidence regarding the impact of the exposure to anesthetic and sedative agents on neurodevelopment during the period of rapid brain growth in the first 3 years of life. Though much of the definitive data demonstrating anesthesia-induced neurotoxi...

journal_title：Current treatment options in neurology

authors： Vinson AE,Houck CS

更新日期：2018-10-13 00:00:00

abstract：:Neuromyelitis optica (NMO, Devic's syndrome) is characterized by concurrence of optic neuritis and transverse myelitis, typically associated with a lesion in the spinal cord extending over three or more vertebral segments. It is an inflammatory, demyelinating central nervous system disorder, and although it is most co...

journal_title：Current treatment options in neurology

authors： Wingerchuk DM,Weinshenker BG

更新日期：2008-01-01 00:00:00