Abstract:
OPINION STATEMENT:The recognition of the diagnosis of migraine in the pediatric population is increasing. Early and aggressive treatment of migraine in children and adolescents with the use of over-the-counter medications has proven effective. In addition, the off-label use of many migraine-specific medications is often accepted in the absence of sufficient evidence-based trials. Mild to severe cases of migraine should be treated with NSAIDs, with triptans used for moderate to severe headaches that are unresponsive to over-the-counter therapy. Rescue medication including dihydroergotamine (DHE) should be used for intractable migraines, preferably in the hospital setting. In patients with associated symptoms of nausea and vomiting, antiemetics with antidopaminergic properties can be helpful through their action on central migraine generation. Furthermore, patients and families should be educated about nonpharmacologic aspects of management such as preventing episodic migraine through lifestyle modification and avoidance of triggers.
journal_name
Curr Treat Options Neuroljournal_title
Current treatment options in neurologyauthors
O'Brien HL,Kabbouche MA,Hershey ADdoi
10.1007/s11940-010-0069-6subject
Has Abstractpub_date
2010-05-01 00:00:00pages
178-85issue
3eissn
1092-8480issn
1534-3138journal_volume
12pub_type
杂志文章abstract:OPINION STATEMENT:Treatment of myoclonus requires an understanding of the physiopathology of the condition. The first step in treatment is to determine if there is an epileptic component to the myoclonus and treat accordingly. Secondly, a review of medications (e.g., opiates) and comorbidities (e.g., hepatic or renal f...
journal_title:Current treatment options in neurology
pub_type: 杂志文章,评审
doi:10.1007/s11940-016-0404-7
更新日期:2016-05-01 00:00:00
abstract:OPINION STATEMENT:Status epilepticus is a neurologic emergency with significant potential morbidity and even mortality. It should be diagnosed and treated as quickly as possible, with concurrent rapid identification of the underlying cause. Nonconvulsive status epilepticus can be difficult to diagnose due to its protea...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-012-0179-4
更新日期:2012-08-01 00:00:00
abstract:OPINION STATEMENT:The diagnosis and appropriate treatment of hyperkinetic movement disorders require a work up of potentially reversible metabolic, infectious and structural disorders as well as side effects of current medication. In pharmacoresistant movement disorders with a disabling impact on quality of life, deep ...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-015-0373-2
更新日期:2015-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Idiopathic normal pressure hydrocephalus (iNPH) is a surgically treatable neurological disorder of the elderly population that is characterized by abnormal ventricular enlargement due to cerebrospinal fluid (CSF) accumulation and gait disturbance, cognitive impairment, or urinary incontinence. The obj...
journal_title:Current treatment options in neurology
pub_type: 杂志文章,评审
doi:10.1007/s11940-019-0604-z
更新日期:2019-12-03 00:00:00
abstract:OPINION STATEMENT:Restless legs syndrome (RLS) is a common, sensorimotor, circadian sleep disorder characterized by the urge to move the legs, particularly at nighttime. It is important to differentiate primary and secondary RLS from other conditions, which can mimic the symptoms of RLS, in particular neuropathy and cr...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-013-0241-x
更新日期:2013-08-01 00:00:00
abstract::The treatment of progressive myoclonus epilepsy (PME) remains a major therapeutic challenge in neurology. Generalized convulsive seizures are often well controlled through classic antiepileptic drugs (AEDs) like valproate and clonazepam, whereas myoclonus, the main symptom that is affecting patients most in their dail...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-002-0001-9
更新日期:2002-01-01 00:00:00
abstract::Although estimates vary, the nervous system appears to be involved in 10% to 15% of patients infected with Borrelia burgdorferi. The resulting disorders, known collectively as neuroborreliosis or nervous system Lyme disease, generally respond well to antimicrobial therapy. Definitive treatment of nervous system infect...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-007-0035-0
更新日期:2007-03-01 00:00:00
abstract:OPINION STATEMENT:CADASIL is a life-threatening and disabling disease. Despite the progress achieved so far, no therapies able to limit the disease progression have been found and only empiric treatments can be employed to relieve the main disease symptoms. Further in vivo studies as well as data aggregation and multi-...
journal_title:Current treatment options in neurology
pub_type: 杂志文章,评审
doi:10.1007/s11940-017-0468-z
更新日期:2017-09-01 00:00:00
abstract::The treatments for obstructive sleep apnea (OSA) described in this paper represent the latest information and data. Nasal continuous positive airway pressure, initially described in 1981, remains the cornerstone of therapy. Advances in mask interfaces, the use of humidification, the downloading of usage information, t...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-009-0038-0
更新日期:2009-09-01 00:00:00
abstract:OPINION STATEMENT:High-grade or malignant gliomas are aggressive cancers. The World Health Organization (WHO) grading system recognizes grade III and grade IV primary brain tumors of astrocytic, oligodendroglial, or mixed lineage. Identification of these tumors is prompted by symptoms such as insidious headaches, seizu...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-010-0077-6
更新日期:2010-07-01 00:00:00
abstract::The neurorehabilitation program for cerebral palsy changes over time. During the first 2 years of life, an infant stimulation program with an emphasis on more than just improving motor deficits is emphasized. The importance of involvement of a knowledgeable therapist cannot be overemphasized. Realistic expectations mu...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-000-0011-4
更新日期:2000-03-01 00:00:00
abstract:OPINION STATEMENT:Neurofibromatosis type 1 (NF1) is a genetic multisystemic disorder involving the skin, the central and peripheral nervous systems, bones, and the cardiovascular and endocrine systems. This condition is caused by inherited or de novo mutations of the NF1 gene at the 17q11.2 chromosomal region, a gene t...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-015-0355-4
更新日期:2015-06-01 00:00:00
abstract:OPINION STATEMENT:Magnetic resonance imaging (MRI) is the gold standard guiding diagnostic and therapeutic management in glioma with its high resolution and possibility to depict blood-brain-barrier disruption when contrast medium is applied. In light of the shifting paradigms revealing distinct tumor subtypes based on...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-015-0384-z
更新日期:2016-01-01 00:00:00
abstract::Hemifacial spasm (HFS) is a peripheral movement disorder caused by direct or indirect compression or distortion of the root exit zone of the seventh cranial nerve, which is most commonly compressed by an arterial loop, but also may be compressed by a tumor, cyst, or aneurysm. All patients with HFS should undergo magne...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-004-0009-4
更新日期:2004-05-01 00:00:00
abstract::Autistic spectrum disorders (ASD) are an often-disabling continuum of disorders affecting two to four in 1000 children. These disorders have a core set of defining features including impaired verbal and nonverbal communication, impaired social interaction, and restricted or repetitive patterns of behavior. The cause o...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-996-0030-x
更新日期:2004-09-01 00:00:00
abstract:OPINION STATEMENT:Therapeutic hypothermia has proven neuroprotective effects in global cerebral ischemia. Indications for hypothermia induction include cardiac arrest and neonatal asphyxia. The two general methods of induced hypothermia are either surface cooling or endovascular cooling. Hypothermia should be induced a...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-012-0201-x
更新日期:2012-12-01 00:00:00
abstract::OPINION STATEMENT: Anemia develops in about 50% of patients hospitalized with traumatic brain injury (TBI) and is recognized as a cause of secondary brain injury. This review examines the effects of anemia and transfusion on TBI patients through a literature search to identify original research on anemia and transfusi...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-012-0167-8
更新日期:2012-04-01 00:00:00
abstract::Standard therapy does not exist for the treatment of primary central nervous system lymphoma. This is because of low patient numbers, slow accrual to clinical trials, and the absence of phase III randomized clinical trials. Neuro-oncologists agree that whole brain irradiation alone is no longer the best treatment opti...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-003-0012-1
更新日期:2003-05-01 00:00:00
abstract::There has been a recent resurgence of interest in therapeutic modalities using transcranial weak electrical stimulation through scalp electrodes, such as trans-cranial direct current stimulation (tDCS), as a means of experimentally modifying and studying brain function and possibly treating psychiatric conditions. A r...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-008-0040-y
更新日期:2008-09-01 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease that usually results in death secondary to respiratory failure. The psychological reaction to the diagnosis of ALS in patient and caregiver has received increasing attention. Reports are highly variable as to the severity of depressive symptoms ...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-006-0030-x
更新日期:2006-09-01 00:00:00
abstract::Migraine is a chronic paroxysmal neurological disorder characterized by multiphase attacks of head pain and a myriad of neurological symptoms. Chronic migraine causes a great personal and societal burden. Many patients are poorly responsive to, or non-compliant with, conventional migraine preventive therapies. For thi...
journal_title:Current treatment options in neurology
pub_type: 杂志文章,评审
doi:10.1007/s11940-019-0555-4
更新日期:2019-03-14 00:00:00
abstract::A sleep history should be taken routinely in patients with epilepsy. Treatment of sleep disorders and improvement in sleep hygiene may improve seizure control, daytime cognitive functioning, and quality of life. Patients with recurrent sleepiness interfering with daily activities or an Epworth Sleepiness Scale score m...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-006-0017-7
更新日期:2006-07-01 00:00:00
abstract::The treatment of complex partial seizure (CPS) begins with accurate diagnosis. Episodes of staring and unresponsiveness due to nonepileptic causes must be ruled out. Absence seizures (typical and atypical petit mal) must be considered because the treatment strategy and prognosis for these seizures are very different f...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-999-0023-7
更新日期:1999-09-01 00:00:00
abstract:OPINION STATEMENT:Autoimmune neuromuscular disorders in childhood include Guillain-Barré syndrome and its variants, chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), juvenile myasthenia gravis (JMG), and juvenile dermatomyositis (JDM), along with other disorders rarely seen in childhood. In general, the...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-011-0146-5
更新日期:2011-12-01 00:00:00
abstract::Neuralgic amyotrophy has a broad variety of clinical manifestations. Although it was initially thought to be a plexopathy, its diverse presentation can include isolated sensory nerves or even cranial nerves. Although neuralgic amyotrophy is usually a benign condition with a good recovery, pain can be a disabling featu...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-009-0011-y
更新日期:2009-03-01 00:00:00
abstract:PURPOSE OF REVIEW:This review will examine the current evidence that genetic and/or epigenetic variation may influence the multiple sclerosis (MS) clinical course, phenotype, and measures of MS severity including disability progression and relapse rate. RECENT FINDINGS:There is little evidence that MS clinical phenoty...
journal_title:Current treatment options in neurology
pub_type: 杂志文章,评审
doi:10.1007/s11940-018-0505-6
更新日期:2018-04-24 00:00:00
abstract::Transplantation of bone marrow or peripheral blood stem cells is increasingly being used to treat a variety of oncologic disorders. These procedures are associated with a large spectrum of neurologic complications that significantly contribute to patient morbidity and mortality. These complications may arise at any ti...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-007-0016-3
更新日期:2007-07-01 00:00:00
abstract::Unfortunately, intravenous alteplase, when administered within 3 hours of symptom onset, remains the only US Food and Drug Administration-approved treatment for acute ischemic stroke; it is now 7 years since its approval. Intra-arterial thrombolysis of middle cerebral and basilar artery occlusions within 6 hours of st...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-003-0028-6
更新日期:2003-09-01 00:00:00
abstract::Herpes simplex virus (HSV) infections are ubiquitous. Children are infected with HSV resulting in totally asymptomatic acquisition to life-threatening disease. Therapy of HSV diseases of children can be considered according to severity and time of acquisition. Neonatal herpes simplex virus infections take one of three...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-002-0040-2
更新日期:2002-05-01 00:00:00
abstract:OPINION STATEMENT:Triptans, selective serotonin receptor agonists, were developed almost 20 years ago and represented a major breakthrough in the treatment of acute migraine attacks. Since then, the triptans have become first-line agents for most patients with migraine, both with and without aura, unless contraindicate...
journal_title:Current treatment options in neurology
pub_type: 杂志文章
doi:10.1007/s11940-010-0082-9
更新日期:2010-09-01 00:00:00