New-onset partial epilepsy in adults.

abstract：:The treatment of complex partial seizure (CPS) begins with accurate diagnosis. Episodes of staring and unresponsiveness due to nonepileptic causes must be ruled out. Absence seizures (typical and atypical petit mal) must be considered because the treatment strategy and prognosis for these seizures are very different f...

journal_title：Current treatment options in neurology

authors： Buchhalter JR

更新日期：1999-09-01 00:00:00

abstract：OPINION STATEMENT:Infantile spasms (IS) represent a major therapeutic challenge, as cessation of spasms and normalization of the electroencephalogram (elimination of hypsarrhythmia) are mandatory to prevent cognitive deterioration in previously healthy infants, or to preserve neurocognitive function among those neurolo...

journal_title：Current treatment options in neurology

authors： Watemberg N

更新日期：2012-08-01 00:00:00

abstract：:After a patient has initiated an antiepileptic drug (AED) and achieved a sustained period of seizure freedom, the bias towards continuing therapy indefinitely can be substantial. Studies show that the rate of seizure recurrence after AED withdrawal is about two to three times the rate in patients who continue AEDs, bu...

journal_title：Current treatment options in neurology

authors： Hixson JD

更新日期：2010-09-01 00:00:00

abstract：OPINION STATEMENT:CADASIL is a life-threatening and disabling disease. Despite the progress achieved so far, no therapies able to limit the disease progression have been found and only empiric treatments can be employed to relieve the main disease symptoms. Further in vivo studies as well as data aggregation and multi-...

journal_title：Current treatment options in neurology

authors： Bersano A,Bedini G,Oskam J,Mariotti C,Taroni F,Baratta S,Parati EA

更新日期：2017-09-01 00:00:00

abstract：:Acute hearing loss (AHL) is a medical urgency. The management of patients presenting with sudden deafness involves detecting the causal mechanism and administering emergency therapeutic drugs to restore hearing by minimizing the period of cellular ischemia to the inner ear. Acute management of AHL consists of administ...

journal_title：Current treatment options in neurology

authors： Tamhankar M,Solomon D

更新日期：2004-01-01 00:00:00

abstract：OPINION STATEMENT:Restless legs syndrome (RLS) is a common, sensorimotor, circadian sleep disorder characterized by the urge to move the legs, particularly at nighttime. It is important to differentiate primary and secondary RLS from other conditions, which can mimic the symptoms of RLS, in particular neuropathy and cr...

journal_title：Current treatment options in neurology

authors： Rios Romenets S,Postuma RB

更新日期：2013-08-01 00:00:00

abstract：:Myasthenia gravis (MG) is an autoimmune disorder characterized clinically by proximal weakness and bulbar symptoms and pathologically by damage to the post-synaptic membrane at the neuromuscular junction. Ocular myasthenia gravis (ocular MG) is a form of myasthenia gravis whereby the patients' weakness is limited to t...

journal_title：Current treatment options in neurology

authors： Porter NC,Salter BC

更新日期：2005-01-01 00:00:00

abstract：OPINION STATEMENT:To date, there are no approved and established pharmacologic treatment options for tauopathies, a very heterogenous group of neuropsychiatric diseases often leading to dementia and clinically diagnosed as atypical Parkinson syndromes. Among these so-called Parkinson plus syndromes are progressive supr...

journal_title：Current treatment options in neurology

authors： Karakaya T,Fußer F,Prvulovic D,Hampel H

更新日期：2012-04-01 00:00:00

abstract：OPINION STATEMENT:Neurofibromatosis type 1 (NF1) is a genetic multisystemic disorder involving the skin, the central and peripheral nervous systems, bones, and the cardiovascular and endocrine systems. This condition is caused by inherited or de novo mutations of the NF1 gene at the 17q11.2 chromosomal region, a gene t...

journal_title：Current treatment options in neurology

authors： Sabatini C,Milani D,Menni F,Tadini G,Esposito S

更新日期：2015-06-01 00:00:00

abstract：:Dystonia is a neurologic disorder that can occur at any age and often results in significant disability. The therapeutic application of botulinum toxin has revolutionized the treatment of this disorder, particularly for the adult-onset focal forms such as cervical dystonia and blepharospasm. The two available commerci...

journal_title：Current treatment options in neurology

authors： Cardona-Garcia OD,Higgins DS,Molho ES

更新日期：2007-05-01 00:00:00

abstract：:Vision disturbances following traumatic brain injury (TBI) include anomalies of accommodation, version, vergence (nonstrabismic, as well as strabismic), photosensitivity, visual field integrity, and ocular health. Traumatic brain injury patients with complex diplopia patterns, noncomitant strabismic anomalies, and adv...

journal_title：Current treatment options in neurology

authors： Kapoor N,Ciuffreda KJ

更新日期：2002-07-01 00:00:00

abstract：OPINION STATEMENT:CLIPPERS for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids, is a steroid-sensitive and steroid-dependent brainstem inflammatory disease of unknown origin. Since its first description in 2010, about 60 cases have been reported throughout the world. The me...

journal_title：Current treatment options in neurology

authors： Taieb G,Allou T,Labauge P

更新日期：2017-05-01 00:00:00

abstract：:Spontaneous intracerebral hemorrhage (ICH) is a devastating neurological event with a 30-day mortality of approximately 40%. Recent research provides new insights into the pathophysiology of ICH-associated edema, with potential molecular and cellular targets for future therapy. Neuroimaging techniques such as gradient...

journal_title：Current treatment options in neurology

authors： Freeman WD,Brott TG

更新日期：2006-03-01 00:00:00

abstract：OPINION STATEMENT:The problem of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA) management remains unsolved. Despite a myriad of therapeutic trials, no convincingly e...

journal_title：Current treatment options in neurology

authors： Pareja JA,Alvarez M,Montojo T

更新日期：2013-02-01 00:00:00

abstract：OPINION STATEMENT:Solid organ transplantation is frequently complicated by a spectrum of seizure types, including single partial-onset or generalized tonic-clonic seizures, acute repetitive seizures or status epilepticus, and sometimes the evolution of symptomatic epilepsy. There is currently no specific evidence invol...

journal_title：Current treatment options in neurology

authors： Shepard PW,St Louis EK

更新日期：2012-08-01 00:00:00

abstract：OPINION STATEMENT:Parkinson's disease (PD) has been increasingly recognized as having a multitude of nonmotor symptoms including psychosis, cognitive impairment and dementia, mood disturbances, fatigue, apathy, and sleep disorders. Psychosis and dementia, in particular, greatly affect quality of life for both patients ...

journal_title：Current treatment options in neurology

authors： Goldman JG,Holden S

更新日期：2014-03-01 00:00:00

abstract：PURPOSE OF REVIEW:People with epilepsy have an increased risk of mortality when compared to the general population. Sudden unexpected death in epilepsy (SUDEP) is the most common cause of epilepsy-related death in children and adults. The purpose of this review is to discuss SUDEP, with an emphasis on SUDEP risk factor...

journal_title：Current treatment options in neurology

authors： Whitney R,Donner EJ

更新日期：2019-02-13 00:00:00

abstract：PURPOSE OF THE REVIEW:Psychosis is broadly defined as a disengagement from reality. It describes syndromes that impair both thought content and thought process. Psychosis negatively impacts an individual's quality of life, in addition to the families caring for them. Psychosis with different types of hallucinations and...

journal_title：Current treatment options in neurology

authors： Rothenberg KG,Rajaram R

更新日期：2019-01-23 00:00:00

abstract：OPINION STATEMENT:Magnetic resonance imaging (MRI) is the gold standard guiding diagnostic and therapeutic management in glioma with its high resolution and possibility to depict blood-brain-barrier disruption when contrast medium is applied. In light of the shifting paradigms revealing distinct tumor subtypes based on...

journal_title：Current treatment options in neurology

authors： Suchorska B,Albert NL,Tonn JC

更新日期：2016-01-01 00:00:00

abstract：:Standard therapy does not exist for the treatment of primary central nervous system lymphoma. This is because of low patient numbers, slow accrual to clinical trials, and the absence of phase III randomized clinical trials. Neuro-oncologists agree that whole brain irradiation alone is no longer the best treatment opti...

journal_title：Current treatment options in neurology

authors： Damek DM

更新日期：2003-05-01 00:00:00

abstract：:Autistic spectrum disorders (ASD) are an often-disabling continuum of disorders affecting two to four in 1000 children. These disorders have a core set of defining features including impaired verbal and nonverbal communication, impaired social interaction, and restricted or repetitive patterns of behavior. The cause o...

journal_title：Current treatment options in neurology

authors： Pinto-Martin J,Levy SE

更新日期：2004-09-01 00:00:00

abstract：OPINION STATEMENT:Kleine-Levin Syndrome [KLS] is often under-recognized and also misdiagnosed. When suspicion for KLS is raised, a thorough clinical evaluation should be performed, including detailed history from family members and a neurologic and psychiatric examination. Additional studies may include PSG, EEG, neuro...

journal_title：Current treatment options in neurology

authors： Sum-Ping O,Guilleminault C

更新日期：2016-06-01 00:00:00

abstract：:Antiepileptic drug (AED) treatment is associated with multiple short- and long-term side effects. Effects on endocrine function, including weight change, reproductive function, thyroid function, and bone health are examples of these side effects. Some AEDs affect weight, resulting in weight gain or loss. Levetiracetam...

journal_title：Current treatment options in neurology

authors： Pack A

更新日期：2005-07-01 00:00:00

abstract：:Hemifacial spasm (HFS) is a peripheral movement disorder caused by direct or indirect compression or distortion of the root exit zone of the seventh cranial nerve, which is most commonly compressed by an arterial loop, but also may be compressed by a tumor, cyst, or aneurysm. All patients with HFS should undergo magne...

journal_title：Current treatment options in neurology

authors： Kemp LW,Reich SG

更新日期：2004-05-01 00:00:00

abstract：OPINION STATEMENT:Restless Legs Syndrome/Willis-Ekbom Disease (RLS/WED) is a common condition characterized by an irresistible urge to move the legs, concomitant with an unpleasant sensation in the lower limbs, which is typically relieved by movement. Symptoms occur predominantly at rest and prevail in the afternoon or...

journal_title：Current treatment options in neurology

authors： Rinaldi F,Galbiati A,Marelli S,Ferini Strambi L,Zucconi M

更新日期：2016-02-01 00:00:00

abstract：OPINION STATEMENT:Myotonic dystrophy (DM1) is the most common form of adult muscular dystrophy. It is a multisystem disorder with a complex pathophysiology. Although inheritance is autosomal dominant, disease variability is attributed to anticipation, a maternal expansion bias, variable penetrance, somatic mosaicism, a...

journal_title：Current treatment options in neurology

authors： Smith CA,Gutmann L

更新日期：2016-12-01 00:00:00

abstract：:The epidemiologic link between increased low-density-lipoprotein (LDL) cholesterol and ischemic stroke is controversial. However, recent trials make it clear that LDL reduction by statin agents in high-risk patients reduces the risk of ischemic stroke. The risk of first stroke is reduced within 1 to 2 years of statin ...

journal_title：Current treatment options in neurology

authors： Bernstein RA

更新日期：2006-11-01 00:00:00

abstract：:Arteriovenous malformations (AVM) are a leading cause of intracerebral hemorrhage, especially among the young. Because they pose a lifelong risk of serious bleeding, definitive treatment to obliterate the AVM should be pursued in the majority of patients. Microsurgical resection of a small AVM located in the superfici...

journal_title：Current treatment options in neurology

authors： Graham GD

更新日期：2002-11-01 00:00:00

abstract：:Neuromyelitis optica (Devic's syndrome) is an uncommon, idiopathic, demyelinating syndrome of the central nervous system that preferentially affects the optic nerves and spinal cord. It frequently is misdiagnosed as severe multiple sclerosis, but usually is readily distinguished from multiple sclerosis in fully develo...

journal_title：Current treatment options in neurology

authors： Wingerchuk DM,Weinshenker BG

更新日期：2005-05-01 00:00:00

abstract：OPINION STATEMENT:Paraneoplastic brain stem encephalitis can occur as an isolated clinical syndrome or, more often, may be part of a more widespread encephalitis. Different antineuronal autoantibodies, such as anti-Hu, anti-Ri, and anti-Ma2 can be associated with the syndrome, and the most frequent tumors are lung and ...

journal_title：Current treatment options in neurology

authors： Blaes F

更新日期：2013-04-01 00:00:00