Abstract：
:Acute hearing loss (AHL) is a medical urgency. The management of patients presenting with sudden deafness involves detecting the causal mechanism and administering emergency therapeutic drugs to restore hearing by minimizing the period of cellular ischemia to the inner ear. Acute management of AHL consists of administering a 10-day course of high-dose corticosteroids (prednisone 60 to 80 mg) until a cause can be established. Magnetic resonance imaging with gadolinium is indicated, with a study dedicated to the internal auditory canals. The natural history of idiopathic AHL is characterized by spontaneous improvement in two thirds of patients. Maximum improvement occurs within 2 weeks of onset of AHL. In the vast majority of patients (>90%), the AHL is idiopathic. For an identifiable etiology, the treatment is specific and may consist of stopping ototoxic medications, repair of perilymphatic fistulas, administering antimicrobial agents for viral or bacterial infections, correction of metabolic imbalances, management of stroke, and possible surgery for cerebellopontine angle tumors. Management of idiopathic AHL is controversial. Various therapeutic agents, such as vasodilators, diuretics, anticoagulants, plasma expanders, contrast agents, and carbogen inhalation, have been tried in single therapy or as a combination therapy. The empiric use of these drugs is mainly based on improving the blood circulation and restoring the oxygen tension to the inner ear. The use of interventional procedures, such as low-density lipoprotein apheresis as well as newer drug delivery systems for corticosteroids, and immunosuppressive agents have opened new options in the treatment of AHL secondary to immune-mediated diseases of the inner ear. Prognosis for AHL is best when patients are seen early, begin recovery within 2 weeks, and have a mild hearing loss (<90 dB) with upward-sloping audiograms. Greater than 90 dB of hearing loss along with flat or down sloping audiogram, advanced age, and presence of vertigo are adverse prognostic factors for recovery of hearing loss.
journal_name
Curr Treat Options Neuroljournal_title
Current treatment options in neurologyauthors
Tamhankar M,Solomon Ddoi
10.1007/s11940-004-0039-ysubject
Has Abstractpub_date
2004-01-01 00:00:00pages
55-65issue
1eissn
1092-8480issn
1534-3138journal_volume
6pub_type
杂志文章abstract：OPINION STATEMENT:When treating a person with epilepsy, one must consider many factors in addition to the obvious need to treat the seizures. Both epilepsy itself and treatment with antiepileptic drugs (AEDs) subject one to numerous potential secondary long-term health concerns. Poor bone health is one of these concern...
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
pub_type： 杂志文章,评审
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journal_title：Current treatment options in neurology
pub_type： 杂志文章
doi：10.1007/s11940-002-0011-7
更新日期：2002-11-01 00:00:00
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journal_title：Current treatment options in neurology
pub_type： 杂志文章
doi：10.1007/s11940-015-0350-9
更新日期：2015-06-01 00:00:00
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journal_title：Current treatment options in neurology
pub_type： 杂志文章,评审
doi：10.1007/s11940-019-0555-4
更新日期：2019-03-14 00:00:00
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journal_title：Current treatment options in neurology
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更新日期：2014-01-01 00:00:00
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
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journal_title：Current treatment options in neurology
pub_type： 杂志文章
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更新日期：2006-11-01 00:00:00
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journal_title：Current treatment options in neurology
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更新日期：2001-11-01 00:00:00
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journal_title：Current treatment options in neurology
pub_type： 杂志文章
doi：
更新日期：2007-09-01 00:00:00
abstract：OPINION STATEMENT:High-grade or malignant gliomas are aggressive cancers. The World Health Organization (WHO) grading system recognizes grade III and grade IV primary brain tumors of astrocytic, oligodendroglial, or mixed lineage. Identification of these tumors is prompted by symptoms such as insidious headaches, seizu...
journal_title：Current treatment options in neurology
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更新日期：2010-07-01 00:00:00
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journal_title：Current treatment options in neurology
pub_type： 杂志文章
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journal_title：Current treatment options in neurology
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