Orthostatic Hypotension in Multiple System Atrophy.

abstract：PURPOSE OF REVIEW:This review will examine the current evidence that genetic and/or epigenetic variation may influence the multiple sclerosis (MS) clinical course, phenotype, and measures of MS severity including disability progression and relapse rate. RECENT FINDINGS:There is little evidence that MS clinical phenoty...

journal_title：Current treatment options in neurology

authors： Jokubaitis VG,Zhou Y,Butzkueven H,Taylor BV

更新日期：2018-04-24 00:00:00

abstract：:Drug-induced parkinsonism (DIP) is condition that mimics Parkinson's disease. Characterized mainly by rigidity and bradykinesia, it has less prominent tremor and gait instability. DIP is generally caused by lipophilic drugs that "block" dopamine D2 receptors in the brain, although presynaptic dopamine depletion, false...

journal_title：Current treatment options in neurology

authors： Susatia F,Fernandez HH

更新日期：2009-05-01 00:00:00

abstract：:Migraine is a chronic paroxysmal neurological disorder characterized by multiphase attacks of head pain and a myriad of neurological symptoms. Chronic migraine causes a great personal and societal burden. Many patients are poorly responsive to, or non-compliant with, conventional migraine preventive therapies. For thi...

journal_title：Current treatment options in neurology

authors： Jain S,Silberstein SD

更新日期：2019-03-14 00:00:00

abstract：OPINION STATEMENT:CLIPPERS for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids, is a steroid-sensitive and steroid-dependent brainstem inflammatory disease of unknown origin. Since its first description in 2010, about 60 cases have been reported throughout the world. The me...

journal_title：Current treatment options in neurology

authors： Taieb G,Allou T,Labauge P

更新日期：2017-05-01 00:00:00

abstract：OPINION STATEMENT:Therapeutic hypothermia has proven neuroprotective effects in global cerebral ischemia. Indications for hypothermia induction include cardiac arrest and neonatal asphyxia. The two general methods of induced hypothermia are either surface cooling or endovascular cooling. Hypothermia should be induced a...

journal_title：Current treatment options in neurology

authors： Song SS,Lyden PD

更新日期：2012-12-01 00:00:00

abstract：OPINION STATEMENT:Use of cannabinoids as medications has a long history. Unfortunately, the prohibition of cannabis and its classification in 1970 as a schedule 1 drug has been a major obstacle in studying these agents in a systematic, controlled manner. The number of class 1 studies (randomized, double-blind, placebo-...

journal_title：Current treatment options in neurology

authors： Catlow B,Sanchez-Ramos J

更新日期：2015-09-01 00:00:00

abstract：:The mainstay of treatment of amyotrophic lateral sclerosis (ALS) is management of symptoms. Health care providers involved in the care of ALS patients should be armed with the most current knowledge about symptomatic management of these patients so that an aggressive approach to controlling symptoms can be undertaken ...

journal_title：Current treatment options in neurology

authors： Thibodeaux LS,Gutierrez A

更新日期：2008-03-01 00:00:00

abstract：:Meningiomas are extra-axial brain tumors of middle-to-late adult life and show a predominance in women. Overall, 90% of meningiomas are benign, 6% atypical, and 2% are malignant. Most patients diagnosed with a meningioma decide to have it removed surgically, and are advised to do so based on their neurologic symptoms....

journal_title：Current treatment options in neurology

authors： Chamberlain MC

更新日期：2001-01-01 00:00:00

abstract：:Acute viral meningitis is the most common infection of the central nervous system. Most cases occur in children and young adults and are due to enteroviruses. Although the common causes of acute viral meningitis still lack treatment with an effective antiviral agent, management of patients is changing because of bette...

journal_title：Current treatment options in neurology

authors： Davis LE

更新日期：2008-05-01 00:00:00

abstract：:Allodynia is a normal part of the untreated migraine attack in most people with episodic migraine and is prevalent in chronic migraine. The extent to which allo-dynia contributes to the pain and disability of migraine attacks is unclear, as is its clinical importance. The presence of allodynia correlates with the seve...

journal_title：Current treatment options in neurology

authors： Young WB

更新日期：2009-01-01 00:00:00

abstract：:Spontaneous intracerebral hemorrhage (ICH) is a devastating neurological event with a 30-day mortality of approximately 40%. Recent research provides new insights into the pathophysiology of ICH-associated edema, with potential molecular and cellular targets for future therapy. Neuroimaging techniques such as gradient...

journal_title：Current treatment options in neurology

authors： Freeman WD,Brott TG

更新日期：2006-03-01 00:00:00

abstract：OPINION STATEMENT:A patient presenting with suspected primary central nervous system (CNS) vasculitis is often difficult to manage. Once the diagnosis is suspected, the clinical course may already be severe and warrant timely aggressive treatment with potentially toxic drugs. Definitive diagnosis is often delayed, requ...

journal_title：Current treatment options in neurology

authors： Gotkine M,Vaknin-Dembinsky A

更新日期：2013-06-01 00:00:00

abstract：:Although estimates vary, the nervous system appears to be involved in 10% to 15% of patients infected with Borrelia burgdorferi. The resulting disorders, known collectively as neuroborreliosis or nervous system Lyme disease, generally respond well to antimicrobial therapy. Definitive treatment of nervous system infect...

journal_title：Current treatment options in neurology

authors： Halperin JJ

更新日期：2007-03-01 00:00:00

abstract：OPINION STATEMENT:Restless Legs Syndrome/Willis-Ekbom Disease (RLS/WED) is a common condition characterized by an irresistible urge to move the legs, concomitant with an unpleasant sensation in the lower limbs, which is typically relieved by movement. Symptoms occur predominantly at rest and prevail in the afternoon or...

journal_title：Current treatment options in neurology

authors： Rinaldi F,Galbiati A,Marelli S,Ferini Strambi L,Zucconi M

更新日期：2016-02-01 00:00:00

abstract：:Dystonia is a neurologic disorder that can occur at any age and often results in significant disability. The therapeutic application of botulinum toxin has revolutionized the treatment of this disorder, particularly for the adult-onset focal forms such as cervical dystonia and blepharospasm. The two available commerci...

journal_title：Current treatment options in neurology

authors： Cardona-Garcia OD,Higgins DS,Molho ES

更新日期：2007-05-01 00:00:00

abstract：OPINION STATEMENT:Pervasive developmental disorders (PDDs), including autistic disorder (autism), Asperger's disorder, and pervasive developmental disorder not otherwise specified (PDD NOS), are neurodevelopmental disorders of childhood onset. These disorders persist throughout the lifespan of affected individuals and ...

journal_title：Current treatment options in neurology

authors： Wink LK,Erickson CA,McDougle CJ

更新日期：2010-11-01 00:00:00

abstract：OPINION STATEMENT:Treatment of myoclonus requires an understanding of the physiopathology of the condition. The first step in treatment is to determine if there is an epileptic component to the myoclonus and treat accordingly. Secondly, a review of medications (e.g., opiates) and comorbidities (e.g., hepatic or renal f...

journal_title：Current treatment options in neurology

authors： Levy A,Chen R

更新日期：2016-05-01 00:00:00

abstract：:Herpes simplex virus (HSV) infections are ubiquitous. Children are infected with HSV resulting in totally asymptomatic acquisition to life-threatening disease. Therapy of HSV diseases of children can be considered according to severity and time of acquisition. Neonatal herpes simplex virus infections take one of three...

journal_title：Current treatment options in neurology

authors： Whitley RJ

更新日期：2002-05-01 00:00:00

abstract：:Arteriovenous malformations (AVM) are a leading cause of intracerebral hemorrhage, especially among the young. Because they pose a lifelong risk of serious bleeding, definitive treatment to obliterate the AVM should be pursued in the majority of patients. Microsurgical resection of a small AVM located in the superfici...

journal_title：Current treatment options in neurology

authors： Graham GD

更新日期：2002-11-01 00:00:00

abstract：OPINION STATEMENT:Myotonic dystrophy (DM1) is the most common form of adult muscular dystrophy. It is a multisystem disorder with a complex pathophysiology. Although inheritance is autosomal dominant, disease variability is attributed to anticipation, a maternal expansion bias, variable penetrance, somatic mosaicism, a...

journal_title：Current treatment options in neurology

authors： Smith CA,Gutmann L

更新日期：2016-12-01 00:00:00

abstract：:Non-rapid eye movement parasomnias are unique physical or experiential phenomena that disrupt sleep. Non-rapid eye movement parasomnias are common in children, but they typically outgrow them. Sleep-stage shifts caused by sleep-disordered breathing and associated arousals may be precipitating events for episodes of pa...

journal_title：Current treatment options in neurology

authors： Farid M,Kushida CA

更新日期：2004-07-01 00:00:00

abstract：:Transplantation of bone marrow or peripheral blood stem cells is increasingly being used to treat a variety of oncologic disorders. These procedures are associated with a large spectrum of neurologic complications that significantly contribute to patient morbidity and mortality. These complications may arise at any ti...

journal_title：Current treatment options in neurology

authors： Mathew RM,Rosenfeld MR

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Psychosis is broadly defined as a disengagement from reality. It describes syndromes that impair both thought content and thought process. Psychosis negatively impacts an individual's quality of life, in addition to the families caring for them. Psychosis with different types of hallucinations and...

journal_title：Current treatment options in neurology

authors： Rothenberg KG,Rajaram R

更新日期：2019-01-23 00:00:00

abstract：:The neurorehabilitation program for cerebral palsy changes over time. During the first 2 years of life, an infant stimulation program with an emphasis on more than just improving motor deficits is emphasized. The importance of involvement of a knowledgeable therapist cannot be overemphasized. Realistic expectations mu...

journal_title：Current treatment options in neurology

authors： Russman BS

更新日期：2000-03-01 00:00:00

abstract：:Acute hearing loss (AHL) is a medical urgency. The management of patients presenting with sudden deafness involves detecting the causal mechanism and administering emergency therapeutic drugs to restore hearing by minimizing the period of cellular ischemia to the inner ear. Acute management of AHL consists of administ...

journal_title：Current treatment options in neurology

authors： Tamhankar M,Solomon D

更新日期：2004-01-01 00:00:00

abstract：OPINION STATEMENT:Narcolepsy is a severe, incurable, neurological disorder that is treated by pharmacological management of its symptoms. The main symptoms are excessive daytime sleepiness (EDS) and cataplexy, although addition symptoms that may require treatment include sleep paralysis, hypnagogic hallucinations, and ...

journal_title：Current treatment options in neurology

authors： Thorpy MJ

更新日期：2015-05-01 00:00:00

abstract：OPINION STATEMENT:Paroxysmal dyskinesia represents a group of uncommon movement disorders that are characterized by episodes of abnormal movements arising from a baseline of normal or nearly normal movement. Recent advances in the genetics of these disorders have helped provide some unification of classification scheme...

journal_title：Current treatment options in neurology

authors： Mink JW

更新日期：2015-06-01 00:00:00

abstract：:Multiple pharmacologic treatments have been studied, but propranolol and primidone have proven to be the most effective medications. It is unlikely that a patient will respond miraculously to another medication if his or her response to propranolol and primidone is minimal. Some subsets of essential tremor, however, s...

journal_title：Current treatment options in neurology

authors： Lambert D,Waters CH

更新日期：1999-03-01 00:00:00

abstract：:Despite increasing recognition of childhood obstructive sleep apnea syndrome (OSAS) as a significant public health problem, treatment of the condition remains inconsistent. Some children are screened using polysomnography and treated only when objective respiratory disturbances are identified. Many others receive aden...

journal_title：Current treatment options in neurology

authors： Hoban TF

更新日期：2005-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the current evidence regarding the impact of the exposure to anesthetic and sedative agents on neurodevelopment during the period of rapid brain growth in the first 3 years of life. Though much of the definitive data demonstrating anesthesia-induced neurotoxi...

journal_title：Current treatment options in neurology

authors： Vinson AE,Houck CS

更新日期：2018-10-13 00:00:00