Allodynia as a complication of migraine: background and management.

Abstract:

:Allodynia is a normal part of the untreated migraine attack in most people with episodic migraine and is prevalent in chronic migraine. The extent to which allo-dynia contributes to the pain and disability of migraine attacks is unclear, as is its clinical importance. The presence of allodynia correlates with the severity and other features of migraine, including aura, migraine-associated symptoms, and motor symptoms. The development of allodynia is associated with resistance to triptan treatment. It is uncertain whether this treatment resistance is due to the accompanying increase in headache severity or whether the development of allo-dynia is the fundamental biologic event causing the new treatment-refractory state. Animal models support the relationship to allodynia. Intravenous ketorolac may be effective at treating migraine with allodynia several hours after the development of the throbbing pain, but prior treatment with opioid analgesics may confer treatment resistance. Occipital nerve blocks rapidly treat migraine pain and allodynia. Uncontrolled studies have successfully used dihydroergotamine to treat episodic and chronic migraine with allodynia.

authors

Young WB

doi

10.1007/s11940-009-0001-0

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

3-9

issue

1

eissn

1092-8480

issn

1534-3138

journal_volume

11

pub_type

杂志文章
  • Therapeutic Approaches in CLIPPERS.

    abstract:OPINION STATEMENT:CLIPPERS for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids, is a steroid-sensitive and steroid-dependent brainstem inflammatory disease of unknown origin. Since its first description in 2010, about 60 cases have been reported throughout the world. The me...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s11940-017-0455-4

    authors: Taieb G,Allou T,Labauge P

    更新日期:2017-05-01 00:00:00

  • Respiratory Failure or Impairment in Amyotrophic Lateral Sclerosis.

    abstract::Respiratory complications account for the majority of deaths occurring in patients suffering from amyotrophic lateral sclerosis (ALS). Patients normally succumb to their illness within an average of 3 to 5 years from the time of diagnosis from complications such as hypoventilation, hypoxemia, hypercarbia, aspiration, ...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-001-0048-z

    authors: Gelanis DF

    更新日期:2001-03-01 00:00:00

  • Apathy and its treatment.

    abstract::Apathy is a common problem observed in numerous neurologic, psychiatric, and other medical conditions. It is independent from other symptoms and has been associated with a variety of negative outcomes. However, little empirical research has been conducted on potential psychologic or pharmacologic treatments for apathy...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:

    authors: Roth RM,Flashman LA,McAllister TW

    更新日期:2007-09-01 00:00:00

  • Myotonic Dystrophy Type 1 Management and Therapeutics.

    abstract:OPINION STATEMENT:Myotonic dystrophy (DM1) is the most common form of adult muscular dystrophy. It is a multisystem disorder with a complex pathophysiology. Although inheritance is autosomal dominant, disease variability is attributed to anticipation, a maternal expansion bias, variable penetrance, somatic mosaicism, a...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s11940-016-0434-1

    authors: Smith CA,Gutmann L

    更新日期:2016-12-01 00:00:00

  • Modern treatment options for intracerebral hemorrhage.

    abstract::Spontaneous intracerebral hemorrhage (ICH) is a devastating neurological event with a 30-day mortality of approximately 40%. Recent research provides new insights into the pathophysiology of ICH-associated edema, with potential molecular and cellular targets for future therapy. Neuroimaging techniques such as gradient...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-006-0005-y

    authors: Freeman WD,Brott TG

    更新日期:2006-03-01 00:00:00

  • Cysticercosis.

    abstract::Cysticercosis, the consequence of ingesting viable eggs of the porcine tapeworm Taenia solium, currently remains one of the most common human parasitic conditions worldwide. Although preventable by the proper disposal of human wastes, cysticercosis of the central nervous system (neurocysticercosis) accounts for a subs...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-000-0052-8

    authors: Bale JF Jr

    更新日期:2000-07-01 00:00:00

  • Treatment Opportunities in Patients With Metabolic Myopathies.

    abstract::Metabolic myopathies are disorders affecting utilization of carbohydrates or fat in the skeletal muscle. Adult patients with metabolic myopathies typically present with exercise-induced pain, contractures or stiffness, fatigue, and myoglobinuria. Symptoms are related to energy failure. Purpose of review In this review...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s11940-017-0473-2

    authors: Ørngreen MC,Vissing J

    更新日期:2017-09-21 00:00:00

  • Infantile spasms: treatment challenges.

    abstract:OPINION STATEMENT:Infantile spasms (IS) represent a major therapeutic challenge, as cessation of spasms and normalization of the electroencephalogram (elimination of hypsarrhythmia) are mandatory to prevent cognitive deterioration in previously healthy infants, or to preserve neurocognitive function among those neurolo...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-012-0181-x

    authors: Watemberg N

    更新日期:2012-08-01 00:00:00

  • Postintensive Care Syndrome in Pediatric Critical Care Survivors: Therapeutic Options to Improve Outcomes After Acquired Brain Injury.

    abstract:PURPOSE OF REVIEW:Children surviving the pediatric intensive care unit (PICU) with neurologic illness or injury have long-term morbidities in physical, cognitive, emotional, and social functioning termed postintensive care syndrome (PICS). In this article, we review acute and longitudinal management strategies availabl...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s11940-019-0586-x

    authors: Williams CN,Hartman ME,Guilliams KP,Guerriero RM,Piantino JA,Bosworth CC,Leonard SS,Bradbury K,Wagner A,Hall TA

    更新日期:2019-09-27 00:00:00

  • Spinal muscular atrophy: advances in research and consensus on care of patients.

    abstract::Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by degeneration of spinal cord motor neurons and muscular atrophy. Advances in recent research have led to understanding of the molecular genetics of SMA. Therapeutic strategies have been developed according to the unique genomic structure o...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-008-0044-7

    authors: Wang CH,Lunn MR

    更新日期:2008-11-01 00:00:00

  • Treatment options for tauopathies.

    abstract:OPINION STATEMENT:To date, there are no approved and established pharmacologic treatment options for tauopathies, a very heterogenous group of neuropsychiatric diseases often leading to dementia and clinically diagnosed as atypical Parkinson syndromes. Among these so-called Parkinson plus syndromes are progressive supr...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-012-0168-7

    authors: Karakaya T,Fußer F,Prvulovic D,Hampel H

    更新日期:2012-04-01 00:00:00

  • Usefulness of PET Imaging to Guide Treatment Options in Gliomas.

    abstract:OPINION STATEMENT:Magnetic resonance imaging (MRI) is the gold standard guiding diagnostic and therapeutic management in glioma with its high resolution and possibility to depict blood-brain-barrier disruption when contrast medium is applied. In light of the shifting paradigms revealing distinct tumor subtypes based on...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-015-0384-z

    authors: Suchorska B,Albert NL,Tonn JC

    更新日期:2016-01-01 00:00:00

  • Treatment of restless legs syndrome.

    abstract:OPINION STATEMENT:Restless legs syndrome (RLS) is a common, sensorimotor, circadian sleep disorder characterized by the urge to move the legs, particularly at nighttime. It is important to differentiate primary and secondary RLS from other conditions, which can mimic the symptoms of RLS, in particular neuropathy and cr...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-013-0241-x

    authors: Rios Romenets S,Postuma RB

    更新日期:2013-08-01 00:00:00

  • Orthostatic Hypotension in Multiple System Atrophy.

    abstract::There is no known way to cure multiple system atrophy or even to slow its insidious progression, but there are opportunities to treat many of its symptoms and complications. Of all the autonomic disturbances it causes, orthostatic hypotension is associated with one of the better chances for successful intervention. Mi...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-000-0005-2

    authors: Riley DE

    更新日期:2000-05-01 00:00:00

  • Non-Rapid Eye Movement Parasomnias.

    abstract::Non-rapid eye movement parasomnias are unique physical or experiential phenomena that disrupt sleep. Non-rapid eye movement parasomnias are common in children, but they typically outgrow them. Sleep-stage shifts caused by sleep-disordered breathing and associated arousals may be precipitating events for episodes of pa...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-004-0032-5

    authors: Farid M,Kushida CA

    更新日期:2004-07-01 00:00:00

  • Thrombolysis in the Treatment of Acute Ischemic Stroke.

    abstract::Unfortunately, intravenous alteplase, when administered within 3 hours of symptom onset, remains the only US Food and Drug Administration-approved treatment for acute ischemic stroke; it is now 7 years since its approval. Intra-arterial thrombolysis of middle cerebral and basilar artery occlusions within 6 hours of st...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-003-0028-6

    authors: Haley EC

    更新日期:2003-09-01 00:00:00

  • Cervicocranial arterial dissection.

    abstract::Cervicocranial arterial dissection (CCAD) occurs when there is a tear in the intimal layer of the carotid or vertebral arteries with subsequent extravasation of blood into the subintimal layers. The dissection may be extradural, intradural, or extend over both segments. The contents of the subintimal layers are highly...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-007-0031-4

    authors: Shah Q,Messé SR

    更新日期:2007-01-01 00:00:00

  • Acute Treatment of Migraine Headache.

    abstract::Migraine is a common, chronic neurologic disorder that affects approximately 12% of the adult population in Western countries. Once migraine is diagnosed, illness severity must be assessed. Clinicians and patients should then work together to develop a treatment plan based on patient needs and preferences. The goals o...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-996-0011-0

    authors: Bigal ME,Lipton RB

    更新日期:2003-11-01 00:00:00

  • Treatment of neurofibromatosis type 1.

    abstract:OPINION STATEMENT:Neurofibromatosis type 1 (NF1) is a genetic multisystemic disorder involving the skin, the central and peripheral nervous systems, bones, and the cardiovascular and endocrine systems. This condition is caused by inherited or de novo mutations of the NF1 gene at the 17q11.2 chromosomal region, a gene t...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-015-0355-4

    authors: Sabatini C,Milani D,Menni F,Tadini G,Esposito S

    更新日期:2015-06-01 00:00:00

  • Current and future treatments in progressive supranuclear palsy.

    abstract::Progressive supranuclear palsy (PSP) is an atypical parkinsonian disorder that, in spite of its growing recognition, is still underdiagnosed. For management, prognosis, and research, an accurate and early diagnosis is essential. PSP is a relentlessly progressive neurodegenerative disorder, clinically characterized by ...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-006-0012-z

    authors: van Balken I,Litvan I

    更新日期:2006-05-01 00:00:00

  • Vagus Nerve Stimulation As Treatment for Epileptic Seizures.

    abstract::Vagus nerve stimulation is a unique therapy for epileptic seizures. Two randomized controlled trials in patients with medically refractory partial seizures have demonstrated efficacy, leading to US Food and Drug Administration approval of vagus nerve stimulation therapy in 1997. Extensive safety testing has not reveal...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-003-0002-3

    authors: Salinsky MC

    更新日期:2003-03-01 00:00:00

  • Treatment of epilepsy in the elderly.

    abstract::The elderly are the most rapidly growing segment of the population, and the incidence of epilepsy in persons over 65 is higher than in any other age group. In nursing homes, its incidence is even higher than in community-dwelling persons of similar ages. About 10% of nursing home residents are being treated with antie...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-008-0026-9

    authors: Leppik IE

    更新日期:2008-07-01 00:00:00

  • Branched-chain Ketoacyl Dehydrogenase Deficiency: Maple Syrup Disease.

    abstract::Classic maple syrup disease can be managed to allow a benign neonatal course, normal growth, and low hospitalization rates. The majority of affected infants that are prospectively managed have good neurodevelopmental outcome; however, acute metabolic intoxication and neurologic deterioration can develop rapidly at any...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-003-0039-3

    authors: Strauss KA,Morton DH

    更新日期:2003-07-01 00:00:00

  • Treatment of epilepsy to optimize bone health.

    abstract:OPINION STATEMENT:When treating a person with epilepsy, one must consider many factors in addition to the obvious need to treat the seizures. Both epilepsy itself and treatment with antiepileptic drugs (AEDs) subject one to numerous potential secondary long-term health concerns. Poor bone health is one of these concern...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-011-0133-x

    authors: Pack AM

    更新日期:2011-08-01 00:00:00

  • Treatment and prevention of cerebrovascular disorders in children.

    abstract::Cerebrovascular disorders are an important cause of mortality and chronic morbidity in children. Ischemic stroke is more common than cerebral venous thrombosis and hemorrhagic stroke in children. Several medical disorders have been associated with stroke in children, and a thorough evaluation of underlying causes is n...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-005-0047-6

    authors: Lynch JK,Pavlakis S,Deveber G

    更新日期:2005-11-01 00:00:00

  • Visual Snow: a Potential Cortical Hyperexcitability Syndrome.

    abstract:OPINION STATEMENT:The purpose of this review is to provide an overview of visual snow (VS) and provide information regarding current treatment options for VS. Visual snow (VS) is a rare disorder manifesting with a persistent visual phenomenon of seeing numerous tiny snow-like dots throughout the visual field, and it ca...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s11940-017-0448-3

    authors: Bou Ghannam A,Pelak VS

    更新日期:2017-03-01 00:00:00

  • Hemifacial Spasm.

    abstract::Hemifacial spasm (HFS) is a peripheral movement disorder caused by direct or indirect compression or distortion of the root exit zone of the seventh cranial nerve, which is most commonly compressed by an arterial loop, but also may be compressed by a tumor, cyst, or aneurysm. All patients with HFS should undergo magne...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-004-0009-4

    authors: Kemp LW,Reich SG

    更新日期:2004-05-01 00:00:00

  • Neurologic Complications of Bone Marrow and Stem-cell Transplantation in Patients with Cancer.

    abstract::Transplantation of bone marrow or peripheral blood stem cells is increasingly being used to treat a variety of oncologic disorders. These procedures are associated with a large spectrum of neurologic complications that significantly contribute to patient morbidity and mortality. These complications may arise at any ti...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-007-0016-3

    authors: Mathew RM,Rosenfeld MR

    更新日期:2007-07-01 00:00:00

  • Treatment of sleep disorders in children.

    abstract::Sleep disorders can have a significant impact on the growth and development of children. Behavioral intervention is the first step in the management of many sleep disorders. Limit-setting is particularly challenging in younger children but must be consistent. Good sleep hygiene practices must be emphasized to adolesce...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-007-0042-1

    authors: Lam JC,Mason TB

    更新日期:2007-11-01 00:00:00

  • B-cell targeting agents in the treatment of multiple sclerosis.

    abstract:OPINION STATEMENT:The aims of this article are to discuss the potential role of B lymphocytes in the pathogenesis of multiple sclerosis (MS) and in the mechanisms of action of approved and emerging disease modifying therapies. Over the last few years, significant progress has been made in the introduction of novel phar...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-013-0232-y

    authors: Braley TJ,Segal BM

    更新日期:2013-06-01 00:00:00