Trigeminal Neuralgia.

Abstract:

:The initial treatment for trigeminal neuralgia is medical. Carbamazepine is the drug of choice. If the patient proves to be intolerant of carbamazepine, a number of second-line drugs are available, though data on their relative efficacy are nonexistent. Phenytoin, baclofen, clonazepam, and sodium valproate are all worthy of consideration. Oxcarbazepine may be as effective as carbamazepine, but its availability is limited. Newer agents being tried in this condition include lamotrigine and gabapentin. Their comparative value has not been established. For patients resistant to or intolerant of drug therapy, interventional or surgical procedures are necessary. For younger, fit patients, particularly with involvement of the first division or all three divisions of the nerve, microvascular decompression is recommended. For older patients, for those not shown to have microvascular cross-compression, and for those not willing to undergo craniectomy, radiofrequency thermal rhizotomy is probably the next treatment of choice. Dogmatic recommendations are not appropriate in the absence of truly comparable data. Other techniques to be considered, if thermal rhizotomy is unsuccessful, include glycerol rhizotomy, balloon compression, partial sensory trigeminal rhizotomy, and peripheral neurectomy. The choice is given in no particular order. Patients offered such treatments require data on the track record of the relevant institution in performing that procedure. Stereotactic radiosurgery is still being evaluated for this condition. Because the associated morbidity is very low, it may become the treatment of choice for the elderly frail patient if longer-term follow-up establishes its continuing benefit.

authors

Perkin GD

doi

10.1007/s11940-996-0009-7

subject

Has Abstract

pub_date

1999-11-01 00:00:00

pages

458-465

issue

5

eissn

1092-8480

issn

1534-3138

journal_volume

1

pub_type

杂志文章
  • Drug-induced parkinsonism.

    abstract::Drug-induced parkinsonism (DIP) is condition that mimics Parkinson's disease. Characterized mainly by rigidity and bradykinesia, it has less prominent tremor and gait instability. DIP is generally caused by lipophilic drugs that "block" dopamine D2 receptors in the brain, although presynaptic dopamine depletion, false...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-009-0019-3

    authors: Susatia F,Fernandez HH

    更新日期:2009-05-01 00:00:00

  • Modern treatment options for intracerebral hemorrhage.

    abstract::Spontaneous intracerebral hemorrhage (ICH) is a devastating neurological event with a 30-day mortality of approximately 40%. Recent research provides new insights into the pathophysiology of ICH-associated edema, with potential molecular and cellular targets for future therapy. Neuroimaging techniques such as gradient...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-006-0005-y

    authors: Freeman WD,Brott TG

    更新日期:2006-03-01 00:00:00

  • Advances in treatment of obstructive sleep apnea syndrome.

    abstract::The treatments for obstructive sleep apnea (OSA) described in this paper represent the latest information and data. Nasal continuous positive airway pressure, initially described in 1981, remains the cornerstone of therapy. Advances in mask interfaces, the use of humidification, the downloading of usage information, t...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-009-0038-0

    authors: Collop NA

    更新日期:2009-09-01 00:00:00

  • Postintensive Care Syndrome in Pediatric Critical Care Survivors: Therapeutic Options to Improve Outcomes After Acquired Brain Injury.

    abstract:PURPOSE OF REVIEW:Children surviving the pediatric intensive care unit (PICU) with neurologic illness or injury have long-term morbidities in physical, cognitive, emotional, and social functioning termed postintensive care syndrome (PICS). In this article, we review acute and longitudinal management strategies availabl...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s11940-019-0586-x

    authors: Williams CN,Hartman ME,Guilliams KP,Guerriero RM,Piantino JA,Bosworth CC,Leonard SS,Bradbury K,Wagner A,Hall TA

    更新日期:2019-09-27 00:00:00

  • Hemifacial Spasm.

    abstract::Hemifacial spasm (HFS) is a peripheral movement disorder caused by direct or indirect compression or distortion of the root exit zone of the seventh cranial nerve, which is most commonly compressed by an arterial loop, but also may be compressed by a tumor, cyst, or aneurysm. All patients with HFS should undergo magne...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-004-0009-4

    authors: Kemp LW,Reich SG

    更新日期:2004-05-01 00:00:00

  • Progressive Myoclonic Epilepsies.

    abstract::The treatment of progressive myoclonus epilepsy (PME) remains a major therapeutic challenge in neurology. Generalized convulsive seizures are often well controlled through classic antiepileptic drugs (AEDs) like valproate and clonazepam, whereas myoclonus, the main symptom that is affecting patients most in their dail...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-002-0001-9

    authors: Uthman BM,Reichl A

    更新日期:2002-01-01 00:00:00

  • Treatment of neurofibromatosis type 1.

    abstract:OPINION STATEMENT:Neurofibromatosis type 1 (NF1) is a genetic multisystemic disorder involving the skin, the central and peripheral nervous systems, bones, and the cardiovascular and endocrine systems. This condition is caused by inherited or de novo mutations of the NF1 gene at the 17q11.2 chromosomal region, a gene t...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-015-0355-4

    authors: Sabatini C,Milani D,Menni F,Tadini G,Esposito S

    更新日期:2015-06-01 00:00:00

  • Neuromyelitis optica.

    abstract::Neuromyelitis optica (NMO, Devic's syndrome) is characterized by concurrence of optic neuritis and transverse myelitis, typically associated with a lesion in the spinal cord extending over three or more vertebral segments. It is an inflammatory, demyelinating central nervous system disorder, and although it is most co...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-008-0007-z

    authors: Wingerchuk DM,Weinshenker BG

    更新日期:2008-01-01 00:00:00

  • Treatment of Sleep Dysfunction in Parkinson's Disease.

    abstract:OPINION STATEMENT:Impaired sleep and alertness affect the majority of Parkinson's disease (PD) patients, negatively impacting safety and quality of life. The etiology of impaired sleep-wake cycle in PD is multifactorial and encompasses medication side effects, nocturnal PD motor symptoms, and presence of co-existent sl...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s11940-017-0461-6

    authors: Amara AW,Chahine LM,Videnovic A

    更新日期:2017-07-01 00:00:00

  • Respiratory Failure or Impairment in Amyotrophic Lateral Sclerosis.

    abstract::Respiratory complications account for the majority of deaths occurring in patients suffering from amyotrophic lateral sclerosis (ALS). Patients normally succumb to their illness within an average of 3 to 5 years from the time of diagnosis from complications such as hypoventilation, hypoxemia, hypercarbia, aspiration, ...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-001-0048-z

    authors: Gelanis DF

    更新日期:2001-03-01 00:00:00

  • Central nervous system vasculitis.

    abstract:OPINION STATEMENT:A patient presenting with suspected primary central nervous system (CNS) vasculitis is often difficult to manage. Once the diagnosis is suspected, the clinical course may already be severe and warrant timely aggressive treatment with potentially toxic drugs. Definitive diagnosis is often delayed, requ...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-013-0227-8

    authors: Gotkine M,Vaknin-Dembinsky A

    更新日期:2013-06-01 00:00:00

  • Subdural Empyema.

    abstract::Subdural empyema represents loculated infection between the outermost layer of the meninges, the dura, and the arachnoid. The empyema may develop intracranially or in the spinal canal. Intracranial subdural empyema is most frequently a complication of sinusitis or, less frequently, otitis or neurosurgical procedures. ...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-003-0019-7

    authors: Greenlee JE

    更新日期:2003-01-01 00:00:00

  • DBS in Dystonia and Other Hyperkinetic Movement Disorders.

    abstract:OPINION STATEMENT:The diagnosis and appropriate treatment of hyperkinetic movement disorders require a work up of potentially reversible metabolic, infectious and structural disorders as well as side effects of current medication. In pharmacoresistant movement disorders with a disabling impact on quality of life, deep ...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-015-0373-2

    authors: Barbey A,Bloch J,Vingerhoets FJ

    更新日期:2015-09-01 00:00:00

  • Complex Partial Seizures in Children.

    abstract::The treatment of complex partial seizure (CPS) begins with accurate diagnosis. Episodes of staring and unresponsiveness due to nonepileptic causes must be ruled out. Absence seizures (typical and atypical petit mal) must be considered because the treatment strategy and prognosis for these seizures are very different f...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-999-0023-7

    authors: Buchhalter JR

    更新日期:1999-09-01 00:00:00

  • Cholesterol lowering to prevent stroke: who, when, and how?

    abstract::The epidemiologic link between increased low-density-lipoprotein (LDL) cholesterol and ischemic stroke is controversial. However, recent trials make it clear that LDL reduction by statin agents in high-risk patients reduces the risk of ischemic stroke. The risk of first stroke is reduced within 1 to 2 years of statin ...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-006-0039-1

    authors: Bernstein RA

    更新日期:2006-11-01 00:00:00

  • Treatment of sleep disorders in children.

    abstract::Sleep disorders can have a significant impact on the growth and development of children. Behavioral intervention is the first step in the management of many sleep disorders. Limit-setting is particularly challenging in younger children but must be consistent. Good sleep hygiene practices must be emphasized to adolesce...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-007-0042-1

    authors: Lam JC,Mason TB

    更新日期:2007-11-01 00:00:00

  • Acute Hearing Loss.

    abstract::Acute hearing loss (AHL) is a medical urgency. The management of patients presenting with sudden deafness involves detecting the causal mechanism and administering emergency therapeutic drugs to restore hearing by minimizing the period of cellular ischemia to the inner ear. Acute management of AHL consists of administ...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-004-0039-y

    authors: Tamhankar M,Solomon D

    更新日期:2004-01-01 00:00:00

  • Spinal muscular atrophy: advances in research and consensus on care of patients.

    abstract::Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by degeneration of spinal cord motor neurons and muscular atrophy. Advances in recent research have led to understanding of the molecular genetics of SMA. Therapeutic strategies have been developed according to the unique genomic structure o...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-008-0044-7

    authors: Wang CH,Lunn MR

    更新日期:2008-11-01 00:00:00

  • Myotonic Dystrophy Type 1 Management and Therapeutics.

    abstract:OPINION STATEMENT:Myotonic dystrophy (DM1) is the most common form of adult muscular dystrophy. It is a multisystem disorder with a complex pathophysiology. Although inheritance is autosomal dominant, disease variability is attributed to anticipation, a maternal expansion bias, variable penetrance, somatic mosaicism, a...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s11940-016-0434-1

    authors: Smith CA,Gutmann L

    更新日期:2016-12-01 00:00:00

  • Acute and recurrent viral meningitis.

    abstract::Acute viral meningitis is the most common infection of the central nervous system. Most cases occur in children and young adults and are due to enteroviruses. Although the common causes of acute viral meningitis still lack treatment with an effective antiviral agent, management of patients is changing because of bette...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-008-0018-9

    authors: Davis LE

    更新日期:2008-05-01 00:00:00

  • Neuralgic amyotrophy.

    abstract::Neuralgic amyotrophy has a broad variety of clinical manifestations. Although it was initially thought to be a plexopathy, its diverse presentation can include isolated sensory nerves or even cranial nerves. Although neuralgic amyotrophy is usually a benign condition with a good recovery, pain can be a disabling featu...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-009-0011-y

    authors: Santana L,Gutierrez A

    更新日期:2009-03-01 00:00:00

  • Antiphospholipid Antibody Syndrome.

    abstract::When the diagnosis of antiphospholipid antibody syndrome (aPS) is being considered in persons who have experienced an ischemic stroke or a transient ischemic attack, it is important to gauge how well the history and laboratory data fit with this diagnosis as opposed to other causes of infarct. The fewer the number of ...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-000-0043-9

    authors: Jacobs BS,Levine SR

    更新日期:2000-09-01 00:00:00

  • Cerebral vasospasm after aneurysmal subarachnoid hemorrhage and traumatic brain injury.

    abstract:OPINION STATEMENT:Cerebral vasospasm (cVSP) consists of the vasoconstriction of large and small intracranial vessels which can lead to cerebral hypoperfusion, and in extreme cases, delayed ischemic deficits with stroke. While most commonly observed after aneurysmal subarachnoid hemorrhage (aSAH), cVSP can also occur af...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-013-0278-x

    authors: Izzy S,Muehlschlegel S

    更新日期:2014-01-01 00:00:00

  • Cervicocranial arterial dissection.

    abstract::Cervicocranial arterial dissection (CCAD) occurs when there is a tear in the intimal layer of the carotid or vertebral arteries with subsequent extravasation of blood into the subintimal layers. The dissection may be extradural, intradural, or extend over both segments. The contents of the subintimal layers are highly...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-007-0031-4

    authors: Shah Q,Messé SR

    更新日期:2007-01-01 00:00:00

  • Meningiomas.

    abstract::Meningiomas are extra-axial brain tumors of middle-to-late adult life and show a predominance in women. Overall, 90% of meningiomas are benign, 6% atypical, and 2% are malignant. Most patients diagnosed with a meningioma decide to have it removed surgically, and are advised to do so based on their neurologic symptoms....

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-001-0025-6

    authors: Chamberlain MC

    更新日期:2001-01-01 00:00:00

  • Treatment of psychosis and dementia in Parkinson's disease.

    abstract:OPINION STATEMENT:Parkinson's disease (PD) has been increasingly recognized as having a multitude of nonmotor symptoms including psychosis, cognitive impairment and dementia, mood disturbances, fatigue, apathy, and sleep disorders. Psychosis and dementia, in particular, greatly affect quality of life for both patients ...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-013-0281-2

    authors: Goldman JG,Holden S

    更新日期:2014-03-01 00:00:00

  • Immunotherapeutics for autoimmune encephalopathies and dementias.

    abstract:OPINION STATEMENT:The timely implementation of immunotherapy is key to successful treatment of autoimmune encephalopathies or dementias (from here on will be referred to as autoimmune encephalopathies). There are different levels of diagnostic certainty which should guide the immunological treatment of autoimmune encep...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-013-0251-8

    authors: McKeon A

    更新日期:2013-12-01 00:00:00

  • Treatment of nonconvulsive status epilepticus.

    abstract:OPINION STATEMENT:Status epilepticus is a neurologic emergency with significant potential morbidity and even mortality. It should be diagnosed and treated as quickly as possible, with concurrent rapid identification of the underlying cause. Nonconvulsive status epilepticus can be difficult to diagnose due to its protea...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-012-0179-4

    authors: Pang T,Drislane FW

    更新日期:2012-08-01 00:00:00

  • One Giant Step for Giant Cell Arteritis: Updates in Diagnosis and Treatment.

    abstract:Purpose of Review:Giant cell arteritis (GCA), a medium and large vessel vasculitis occurring in the aged, remains a formidable disease, capable of taking both vision and life, through a multitude of vascular complications. Our understanding of the spectrum of its manifestations has grown over the years, to include limb...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s11940-020-00660-2

    authors: Dinkin M,Johnson E

    更新日期:2021-01-01 00:00:00

  • Cannabinoids for the Treatment of Movement Disorders.

    abstract:OPINION STATEMENT:Use of cannabinoids as medications has a long history. Unfortunately, the prohibition of cannabis and its classification in 1970 as a schedule 1 drug has been a major obstacle in studying these agents in a systematic, controlled manner. The number of class 1 studies (randomized, double-blind, placebo-...

    journal_title:Current treatment options in neurology

    pub_type: 杂志文章

    doi:10.1007/s11940-015-0370-5

    authors: Catlow B,Sanchez-Ramos J

    更新日期:2015-09-01 00:00:00