B-cell targeting agents in the treatment of multiple sclerosis.

abstract：OPINION STATEMENT:Therapeutic hypothermia has proven neuroprotective effects in global cerebral ischemia. Indications for hypothermia induction include cardiac arrest and neonatal asphyxia. The two general methods of induced hypothermia are either surface cooling or endovascular cooling. Hypothermia should be induced a...

journal_title：Current treatment options in neurology

authors： Song SS,Lyden PD

更新日期：2012-12-01 00:00:00

abstract：OPINION STATEMENT:Cerebral vasospasm (cVSP) consists of the vasoconstriction of large and small intracranial vessels which can lead to cerebral hypoperfusion, and in extreme cases, delayed ischemic deficits with stroke. While most commonly observed after aneurysmal subarachnoid hemorrhage (aSAH), cVSP can also occur af...

journal_title：Current treatment options in neurology

authors： Izzy S,Muehlschlegel S

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Psychosis is broadly defined as a disengagement from reality. It describes syndromes that impair both thought content and thought process. Psychosis negatively impacts an individual's quality of life, in addition to the families caring for them. Psychosis with different types of hallucinations and...

journal_title：Current treatment options in neurology

authors： Rothenberg KG,Rajaram R

更新日期：2019-01-23 00:00:00

abstract：OPINION STATEMENT:The problem of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA) management remains unsolved. Despite a myriad of therapeutic trials, no convincingly e...

journal_title：Current treatment options in neurology

authors： Pareja JA,Alvarez M,Montojo T

更新日期：2013-02-01 00:00:00

abstract：:Dystonia is a neurologic disorder that can occur at any age and often results in significant disability. The therapeutic application of botulinum toxin has revolutionized the treatment of this disorder, particularly for the adult-onset focal forms such as cervical dystonia and blepharospasm. The two available commerci...

journal_title：Current treatment options in neurology

authors： Cardona-Garcia OD,Higgins DS,Molho ES

更新日期：2007-05-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease that usually results in death secondary to respiratory failure. The psychological reaction to the diagnosis of ALS in patient and caregiver has received increasing attention. Reports are highly variable as to the severity of depressive symptoms ...

journal_title：Current treatment options in neurology

authors： Stromberg SF,Weiss DB

更新日期：2006-09-01 00:00:00

abstract：:Cervicocranial arterial dissection (CCAD) occurs when there is a tear in the intimal layer of the carotid or vertebral arteries with subsequent extravasation of blood into the subintimal layers. The dissection may be extradural, intradural, or extend over both segments. The contents of the subintimal layers are highly...

journal_title：Current treatment options in neurology

authors： Shah Q,Messé SR

更新日期：2007-01-01 00:00:00

abstract：:Given our current knowledge, there is a need for the early institution of immunomodulatory therapy, especially for patients with poor prognostic factors (motor and cerebellar symptoms, frequent disease exacerbations, and a high level of activity on magnetic resonance imaging ). Patients who progress despite immunomodu...

journal_title：Current treatment options in neurology

authors： Bielekova B,Martin R

更新日期：1999-07-01 00:00:00

abstract：OPINION STATEMENT:The recognition of the diagnosis of migraine in the pediatric population is increasing. Early and aggressive treatment of migraine in children and adolescents with the use of over-the-counter medications has proven effective. In addition, the off-label use of many migraine-specific medications is ofte...

journal_title：Current treatment options in neurology

authors： O'Brien HL,Kabbouche MA,Hershey AD

更新日期：2010-05-01 00:00:00

abstract：:OPINION STATEMENT: Anemia develops in about 50% of patients hospitalized with traumatic brain injury (TBI) and is recognized as a cause of secondary brain injury. This review examines the effects of anemia and transfusion on TBI patients through a literature search to identify original research on anemia and transfusi...

journal_title：Current treatment options in neurology

authors： Kramer AH,Le Roux P

更新日期：2012-04-01 00:00:00

abstract：OPINION STATEMENT:Solid organ transplantation is frequently complicated by a spectrum of seizure types, including single partial-onset or generalized tonic-clonic seizures, acute repetitive seizures or status epilepticus, and sometimes the evolution of symptomatic epilepsy. There is currently no specific evidence invol...

journal_title：Current treatment options in neurology

authors： Shepard PW,St Louis EK

更新日期：2012-08-01 00:00:00

abstract：:Myasthenia gravis (MG) is an autoimmune disorder characterized clinically by proximal weakness and bulbar symptoms and pathologically by damage to the post-synaptic membrane at the neuromuscular junction. Ocular myasthenia gravis (ocular MG) is a form of myasthenia gravis whereby the patients' weakness is limited to t...

journal_title：Current treatment options in neurology

authors： Porter NC,Salter BC

更新日期：2005-01-01 00:00:00

abstract：:Subdural empyema represents loculated infection between the outermost layer of the meninges, the dura, and the arachnoid. The empyema may develop intracranially or in the spinal canal. Intracranial subdural empyema is most frequently a complication of sinusitis or, less frequently, otitis or neurosurgical procedures. ...

journal_title：Current treatment options in neurology

authors： Greenlee JE

更新日期：2003-01-01 00:00:00

abstract：:A sleep history should be taken routinely in patients with epilepsy. Treatment of sleep disorders and improvement in sleep hygiene may improve seizure control, daytime cognitive functioning, and quality of life. Patients with recurrent sleepiness interfering with daily activities or an Epworth Sleepiness Scale score m...

journal_title：Current treatment options in neurology

authors： Herman ST

更新日期：2006-07-01 00:00:00

abstract：:There has been a recent resurgence of interest in therapeutic modalities using transcranial weak electrical stimulation through scalp electrodes, such as trans-cranial direct current stimulation (tDCS), as a means of experimentally modifying and studying brain function and possibly treating psychiatric conditions. A r...

journal_title：Current treatment options in neurology

authors： Bikson M,Bulow P,Stiller JW,Datta A,Battaglia F,Karnup SV,Postolache TT

更新日期：2008-09-01 00:00:00

abstract：:Apathy is a common problem observed in numerous neurologic, psychiatric, and other medical conditions. It is independent from other symptoms and has been associated with a variety of negative outcomes. However, little empirical research has been conducted on potential psychologic or pharmacologic treatments for apathy...

journal_title：Current treatment options in neurology

authors： Roth RM,Flashman LA,McAllister TW

更新日期：2007-09-01 00:00:00

abstract：OPINION STATEMENT:Paraneoplastic brain stem encephalitis can occur as an isolated clinical syndrome or, more often, may be part of a more widespread encephalitis. Different antineuronal autoantibodies, such as anti-Hu, anti-Ri, and anti-Ma2 can be associated with the syndrome, and the most frequent tumors are lung and ...

journal_title：Current treatment options in neurology

authors： Blaes F

更新日期：2013-04-01 00:00:00

abstract：OPINION STATEMENT:Triptans, selective serotonin receptor agonists, were developed almost 20 years ago and represented a major breakthrough in the treatment of acute migraine attacks. Since then, the triptans have become first-line agents for most patients with migraine, both with and without aura, unless contraindicate...

journal_title：Current treatment options in neurology

authors： Cole AK,Marmura MJ

更新日期：2010-09-01 00:00:00

abstract：OPINION STATEMENT:Restless legs syndrome (RLS) is a common, sensorimotor, circadian sleep disorder characterized by the urge to move the legs, particularly at nighttime. It is important to differentiate primary and secondary RLS from other conditions, which can mimic the symptoms of RLS, in particular neuropathy and cr...

journal_title：Current treatment options in neurology

authors： Rios Romenets S,Postuma RB

更新日期：2013-08-01 00:00:00

abstract：:Metabolic myopathies are disorders affecting utilization of carbohydrates or fat in the skeletal muscle. Adult patients with metabolic myopathies typically present with exercise-induced pain, contractures or stiffness, fatigue, and myoglobinuria. Symptoms are related to energy failure. Purpose of review In this review...

journal_title：Current treatment options in neurology

authors： Ørngreen MC,Vissing J

更新日期：2017-09-21 00:00:00

abstract：:The elderly are the most rapidly growing segment of the population, and the incidence of epilepsy in persons over 65 is higher than in any other age group. In nursing homes, its incidence is even higher than in community-dwelling persons of similar ages. About 10% of nursing home residents are being treated with antie...

journal_title：Current treatment options in neurology

authors： Leppik IE

更新日期：2008-07-01 00:00:00

abstract：:When the diagnosis of antiphospholipid antibody syndrome (aPS) is being considered in persons who have experienced an ischemic stroke or a transient ischemic attack, it is important to gauge how well the history and laboratory data fit with this diagnosis as opposed to other causes of infarct. The fewer the number of ...

journal_title：Current treatment options in neurology

authors： Jacobs BS,Levine SR

更新日期：2000-09-01 00:00:00

abstract：:Drug-induced parkinsonism (DIP) is condition that mimics Parkinson's disease. Characterized mainly by rigidity and bradykinesia, it has less prominent tremor and gait instability. DIP is generally caused by lipophilic drugs that "block" dopamine D2 receptors in the brain, although presynaptic dopamine depletion, false...

journal_title：Current treatment options in neurology

authors： Susatia F,Fernandez HH

更新日期：2009-05-01 00:00:00

abstract：:Meningiomas are extra-axial brain tumors of middle-to-late adult life and show a predominance in women. Overall, 90% of meningiomas are benign, 6% atypical, and 2% are malignant. Most patients diagnosed with a meningioma decide to have it removed surgically, and are advised to do so based on their neurologic symptoms....

journal_title：Current treatment options in neurology

authors： Chamberlain MC

更新日期：2001-01-01 00:00:00

abstract：OPINION STATEMENT:Paroxysmal dyskinesia represents a group of uncommon movement disorders that are characterized by episodes of abnormal movements arising from a baseline of normal or nearly normal movement. Recent advances in the genetics of these disorders have helped provide some unification of classification scheme...

journal_title：Current treatment options in neurology

authors： Mink JW

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Idiopathic normal pressure hydrocephalus (iNPH) is a surgically treatable neurological disorder of the elderly population that is characterized by abnormal ventricular enlargement due to cerebrospinal fluid (CSF) accumulation and gait disturbance, cognitive impairment, or urinary incontinence. The obj...

journal_title：Current treatment options in neurology

authors： Isaacs AM,Williams MA,Hamilton MG

更新日期：2019-12-03 00:00:00

abstract：OPINION STATEMENT:The diagnosis and appropriate treatment of hyperkinetic movement disorders require a work up of potentially reversible metabolic, infectious and structural disorders as well as side effects of current medication. In pharmacoresistant movement disorders with a disabling impact on quality of life, deep ...

journal_title：Current treatment options in neurology

authors： Barbey A,Bloch J,Vingerhoets FJ

更新日期：2015-09-01 00:00:00

abstract：OPINION STATEMENT:Narcolepsy is a severe, incurable, neurological disorder that is treated by pharmacological management of its symptoms. The main symptoms are excessive daytime sleepiness (EDS) and cataplexy, although addition symptoms that may require treatment include sleep paralysis, hypnagogic hallucinations, and ...

journal_title：Current treatment options in neurology

authors： Thorpy MJ

更新日期：2015-05-01 00:00:00

abstract：OPINION STATEMENT:Neurofibromatosis type 1 (NF1) is a genetic multisystemic disorder involving the skin, the central and peripheral nervous systems, bones, and the cardiovascular and endocrine systems. This condition is caused by inherited or de novo mutations of the NF1 gene at the 17q11.2 chromosomal region, a gene t...

journal_title：Current treatment options in neurology

authors： Sabatini C,Milani D,Menni F,Tadini G,Esposito S

更新日期：2015-06-01 00:00:00

abstract：:Standard therapy does not exist for the treatment of primary central nervous system lymphoma. This is because of low patient numbers, slow accrual to clinical trials, and the absence of phase III randomized clinical trials. Neuro-oncologists agree that whole brain irradiation alone is no longer the best treatment opti...

journal_title：Current treatment options in neurology

authors： Damek DM

更新日期：2003-05-01 00:00:00