Fluorometric characterization of dityrosine: complex formation with boric acid and borate ion.

abstract：:To analyse the species of genes expressed in a cleavage stage mouse embryo, we have constructed a cDNA library containing 3.0 x 10(5) independent clones from about 2 x 10(3) embryos at the 8-cell stage of development. Endo A cDNA prepared from parietal yolk sac endoderm like PYS-2 cells was used to screen the library....

journal_title：Biochemical and biophysical research communications

authors： Nozaki M,Murata K,Morita T,Matsushiro A

更新日期：1988-08-15 00:00:00

abstract：:Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that mediates rapid degradation of transcripts bearing premature translation termination codons (PTCs) and thereby limits the expression of unproductively processed mRNAs and the synthesis of C-terminally truncated peptides. Both its importance as a means to...

journal_title：Biochemical and biophysical research communications

authors： Boelz S,Neu-Yilik G,Gehring NH,Hentze MW,Kulozik AE

更新日期：2006-10-13 00:00:00

abstract：:To identify the target autoantigens in Vogt-Koyanagi-Harada disease, we made use of an immunoscreening of a bovine uveal cDNA expression library with serum samples obtained from patients with Vogt-Koyanagi-Harada disease. We identified a novel bovine antigen and homologous human autoantigen and designated it as UACA (...

journal_title：Biochemical and biophysical research communications

authors： Yamada K,Senju S,Nakatsura T,Murata Y,Ishihara M,Nakamura S,Ohno S,Negi A,Nishimura Y

更新日期：2001-02-02 00:00:00

abstract：:Parathyroid hormone-related protein (PTHrP) is produced by various normal and neoplastic tissues. Even if the physiological function(s) of PTHrP is unclear, evidence suggests that the protein may participate in the local regulation of smooth muscle contractility. We show here that PTHrP is produced in endothelial cell...

journal_title：Biochemical and biophysical research communications

authors： Rian E,Jemtland R,Olstad OK,Endresen MJ,Grasser WA,Thiede MA,Henriksen T,Bucht E,Gautvik KM

更新日期：1994-01-28 00:00:00

abstract：:Phenylenediamine derivatives can function as a hydrogen donor and reportedly exert various biological actions including cytoprotective effects against oxidative stress, possibly by acting as an antioxidant. Previous studies showed that feeding of such compounds to mice reduced their body weight, but the precise mechan...

journal_title：Biochemical and biophysical research communications

authors： Yanagitai M,Kitagawa T,Okawa K,Koyama H,Satoh T

更新日期：2012-01-06 00:00:00

abstract：:Affinity column-purified GABA-benzodiazepine receptor protein from bovine brain was photoaffinity labeled with both [3H]flunitrazepam and [3H]muscimol. Gel electrophoresis in sodium dodecyl sulfate revealed that the benzodiazepine binding site labeled with [3H]flunitrazepam was primarily associated with a major peptid...

journal_title：Biochemical and biophysical research communications

authors： Deng L,Ransom RW,Olsen RW

更新日期：1986-08-14 00:00:00

abstract：:Urokinase plasminogen activator (uPA) and its receptor uPAR play a major role in immune cell-mediated, including natural killer (NK) cell-mediated, degradation of extracellular matrices. Herein, we investigate the effects of IL-2 on NK cell uPA and uPAR. RNA and protein analyses showed upregulation of uPA and uPAR fol...

journal_title：Biochemical and biophysical research communications

authors： Al-Atrash G,Shetty S,Idell S,Xue Y,Kitson RP,Halady PK,Goldfarb RH

更新日期：2002-03-22 00:00:00

abstract：:The crystal structure of the NTF2-like domain of the Drosophila homolog of Ras GTPase SH3 Binding Protein (G3BP), Rasputin, was determined at 2.7Å resolution. The overall structure is highly similar to nuclear transport factor 2: It is a homodimer comprised of a β-sheet and three α-helices forming a cone-like shape. H...

journal_title：Biochemical and biophysical research communications

authors： Vognsen T,Kristensen O

更新日期：2012-03-30 00:00:00

abstract：:Electrophoretic analysis of murine anterior pituitary extract revealed five major proteins of Mr 13,000-18,000 (designated P13, P14, P16, P17, and P18 according to Mr), three of which, P16, P17, and P18, were markedly influenced by estradiol benzoate and perphenazine in a manner similar to that of growth hormone, and ...

journal_title：Biochemical and biophysical research communications

authors： Sinha YN,Jacobsen BP

更新日期：1988-10-14 00:00:00

abstract：:Actin-related proteins share significant homology with conventional actins and are classified into subfamilies based on the similarity of their sequences and functions. The Arp4 subfamily of Arps is localized in the nucleus, and a mammalian isoform, ArpNbeta (also known as BAF53), is a component of the chromatin remod...

journal_title：Biochemical and biophysical research communications

authors： Kuroda Y,Oma Y,Nishimori K,Ohta T,Harata M

更新日期：2002-11-29 00:00:00

abstract：:PARP1 is an important enzyme involved in various patho-physiological phenomena such as ischemia/reperfusion (I/R) injury, which occurs when blood flow is restored after cerebral infarction, myocardial infarction and transplantation of various organs. I/R-induced PARP1 over-activation is mediated by production of react...

journal_title：Biochemical and biophysical research communications

authors： Nagai W,Okita N,Matsumoto H,Okado H,Oku M,Higami Y

更新日期：2012-04-27 00:00:00

abstract：:We characterized the function of mouse organic cation transporter OCT2 (TC 2.A.19.1.5) in comparison with that of OCT1 (TC 2.A.19.1.1). Uptake of [(3)H]1-methyl-4-phenylpyridinium ([(3)H]MPP(+)) by Xenopus laevis oocytes injected with mOCT1 (Slc22a1) or mOCT2 (Slc22a2) cRNA was attenuated by an increase of extracellul...

journal_title：Biochemical and biophysical research communications

authors： Kakehi M,Koyabu N,Nakamura T,Uchiumi T,Kuwano M,Ohtani H,Sawada Y

更新日期：2002-08-23 00:00:00

abstract：:We have isolated, mapped and sequenced the 5' promoter region of the human SH3BGR (SH3-Binding Glutamine Rich) gene located in the Down syndrome region-2, between markers D21S55 and MX1 of human chromosome 21. This region has been postulated as the minimal region for congenital heart disease and 6 facial and dermatogl...

journal_title：Biochemical and biophysical research communications

authors： Vidal-Taboada JM,Bergoñon S,Scartezzini P,Egeo A,Nizetic D,Oliva R

更新日期：1997-12-18 00:00:00

abstract：:Myogenesis is regulated by the basic helix-loop-helix (bHLH) myogenic regulatory factor MyoD, which induces muscle-specific gene expression by binding to the E-box sequence as a heterodimer with ubiquitous bHLH E2A (E12/E47) proteins. Here, we report that a 31-kDa caspase-generated cleavage product of Crk-associated s...

journal_title：Biochemical and biophysical research communications

authors： Jeong DE,Lee EK,Song WK,Kim W

更新日期：2014-02-21 00:00:00

abstract：:Using a PCR-based cloning strategy we have isolated a cDNA from mouse brain and named it fex, because it codes for a novel putative G protein-coupled receptor expressed in follicles. The deduced amino acid sequence shows a higher degree of homology to the family of glycoprotein receptors, namely those for FSH, LH, and...

journal_title：Biochemical and biophysical research communications

authors： Hermey G,Methner A,Schaller HC,Hermans-Borgmeyer I

更新日期：1999-01-08 00:00:00

abstract：:The family C G protein-coupled receptor (GPCR) T1R2 and T1R3 heterodimer functions as a broadly acting sweet taste receptor. Perception of sweet taste is a species-dependent physiological process. It has been widely reported that New World monkeys and rodents are not able to perceive some of the artificial sweeteners ...

journal_title：Biochemical and biophysical research communications

authors： Liu B,Ha M,Meng XY,Khaleduzzaman M,Zhang Z,Li X,Cui M

更新日期：2012-10-19 00:00:00

abstract：:Neurofibromatosis type 1 is a common genetic disease that causes nervous system tumors, and cognitive deficits. It is due to mutations within the NF1 gene, which encodes the Nf1 protein. Nf1 has been shown to be involved in the regulation of Ras, cAMP and actin cytoskeleton dynamics. In this study, using immunofluores...

journal_title：Biochemical and biophysical research communications

authors： Godin F,Villette S,Vallée B,Doudeau M,Morisset-Lopez S,Ardourel M,Hevor T,Pichon C,Bénédetti H

更新日期：2012-02-24 00:00:00

abstract：:Multidrug resistance (MDR) cells can be sensitized to anticancer drugs when treated concomitantly with chemosensitizers. In this study, chemosensitizing effects of 5,6,7,3',4'-pentamethoxyflavone (sinensetin) and its analogs were investigated with respect to in vitro efficacy and structure-activity relationship. Sinen...

journal_title：Biochemical and biophysical research communications

authors： Choi CH,Sun KH,An CS,Yoo JC,Hahm KS,Lee IH,Sohng JK,Kim YC

更新日期：2002-07-26 00:00:00

abstract：:Astrocytes, a large population of glial cells, detect neurotransmitters and respond by increasing intracellular Ca2+ concentration ([Ca2+]i) and releasing chemical molecules called gliotransmitters. Recently discovered Ca2+ influx through transient receptor potential ankyrin 1 (TRPA1) channels is reported to cause spo...

journal_title：Biochemical and biophysical research communications

authors： Takizawa M,Harada K,Nakamura K,Tsuboi T

更新日期：2018-07-02 00:00:00

abstract：:Malignant mesothelioma (MM) is an aggressive and highly chemo-resistant tumour. In this study, we examined cisplatin-induced apoptosis in mouse models of this disease and investigated the role of constitutive and inducible expression of apoptosis related genes in this process. All of the four mouse MM cell lines exami...

journal_title：Biochemical and biophysical research communications

authors： Fox SA,Kusmiaty,Loh SS,Dharmarajan AM,Garlepp MJ

更新日期：2005-11-25 00:00:00

abstract：:We have recently isolated a rat homologue of the Caenorrhabditis elegans lin-10 product. Although rat lin-10 is expressed in the cytosol and membrane fractions of various tissues, it is distributed only in the membrane fraction in brain where it is enriched in the synaptic plasma membrane and postsynaptic density frac...

journal_title：Biochemical and biophysical research communications

authors： Ide N,Hata Y,Hirao K,Irie M,Deguchi M,Yao I,Satoh A,Wada M,Takahashi K,Nakanishi H,Takai Y

更新日期：1998-03-06 00:00:00

abstract：:Global rise in obesity at early age due to overconsumption of energy-dense food is the major health problem which increases the exposure to obesity over longer duration. Recently we reported that the severity of ovarian dysfunction depends on the duration of obesity. In the present study, we examined the consequences ...

journal_title：Biochemical and biophysical research communications

authors： Kannan S,Bhaskaran RS

更新日期：2019-11-12 00:00:00

abstract：:Various bacteria and bacterial products induce in pure, lymphocyte-free bone marrow-derived mononuclear phagocytes (BMMø) the generation of tumor necrosis factor, nitric oxide (NO) synthase, NO and nitrite (NO2-), the flow of L-arginine to citrulline, and tumoricidal activity. The flow of L-arginine to citrulline and ...

journal_title：Biochemical and biophysical research communications

authors： Keller R,Bassetti S,Keist R,Mülsch A,Klauser S

更新日期：1992-05-15 00:00:00

abstract：:A dose-dependent increase in cholesterol absorption was induced by glucose addition (0-75 mM) to the apical medium of TC7 cells, a well-characterized clone of Caco-2. The uptake into the cells and the secretion rate to the basolateral space were both enhanced by glucose and galactose. This up-regulation was suppressed...

journal_title：Biochemical and biophysical research communications

authors： Play B,Salvini S,Haikal Z,Charbonnier M,Harbis A,Roussel M,Lairon D,Jourdheuil-Rahmani D

更新日期：2003-10-17 00:00:00

abstract：:Near infrared spectroscopy with aquaphotomics as a novel approach was assessed for the diagnosis of soybean plants (Glycine max) infected with soybean mosaic virus (SMV) at latent symptomless stage of the disease. Near infrared (NIR) leaf spectra (in the range of 730-1025nm) acquired from soybean plants with and witho...

journal_title：Biochemical and biophysical research communications

authors： Jinendra B,Tamaki K,Kuroki S,Vassileva M,Yoshida S,Tsenkova R

更新日期：2010-07-09 00:00:00

abstract：:Fura-2 loaded pancreatic beta-cells, isolated from obese hyperglycemic mice, were studied with respect to cytoplasmic free Ca2+ concentration ([Ca2+]i), insulin release and efflux of indicator. In the absence of glucose there was a continuous efflux of fura-2, which was markedly increased by stimulation with a high co...

journal_title：Biochemical and biophysical research communications

authors： Arkhammar P,Nilsson T,Berggren PO

更新日期：1989-02-28 00:00:00

abstract：:Cell extracts from wheat embryos have been widely used for mRNA-directed protein production. Here, we found that a significant fraction of exogenous linear RNAs are circularized in a wheat embryo extract. The circularization was seen only in uncapped RNAs. The amount of the circular species reached around 1% of the in...

journal_title：Biochemical and biophysical research communications

authors： Makino S,Sawasaki T,Tozawa Y,Endo Y,Takai K

更新日期：2006-09-08 00:00:00

abstract：:Posttranslational histone modifications play an important role in modulating gene expression and chromatin structure. Here we report the identification of histone H3K79 dimethylation in the simple eukaryote Dictyostelium discoideum. We have deleted the D. discoideum Dot1/KMT4 homologue and demonstrate that it is the s...

journal_title：Biochemical and biophysical research communications

authors： Müller-Taubenberger A,Bönisch C,Fürbringer M,Wittek F,Hake SB

更新日期：2011-01-28 00:00:00

abstract：:We investigated the contributions of dietary fat and dietary carbohydrate to the development of fatty liver induced by western diet (WD). Compared with WD-fed wild type (WT) mice, livers of WD-fed ChREBP(-/-) mice showed lipid droplets of varying sizes around the hepatic lobules, while hepatic triglyceride and cholest...

journal_title：Biochemical and biophysical research communications

authors： Wu W,Tsuchida H,Kato T,Niwa H,Horikawa Y,Takeda J,Iizuka K

更新日期：2015-06-12 00:00:00

abstract：:Lecithin-cholesterol acyltransferase (LCAT) is responsible for the formation of cholesterol esters in plasma and is implicated in the removal of excess cholesterol from peripheral tissues. It is generally accepted that the catalytic mechanism of LCAT is similar to that of serine proteases and lipases involving a Ser, ...

journal_title：Biochemical and biophysical research communications

authors： Adimoolam S,Lee YP,Jonas A

更新日期：1998-02-13 00:00:00