Feasibility study of oral cyclophosphamide salvage therapy for the treatment of heavily pretreated patients with recurrent epithelial ovarian cancer.

abstract：BACKGROUND:We have performed 26 vaginal radical trachelectomies (RTs) for patients with early invasive uterine cervical cancer since 2003 and, to date, have experienced 8 deliveries. The procedure has a high risk for preterm labor and the subsequent occurrence of preterm premature rupture of membranes (pPROM). We repor...

journal_title：International journal of clinical oncology

authors： Takada S,Ishioka S,Endo T,Baba T,Morishita M,Akashi Y,Mizuuchi M,Adachi H,Kim M,Saito T

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Although several reports have discussed the potential of the indocyanine green (ICG) fluorescence technique, its effectiveness and limitations have not been fully evaluated. For the accurate detection of sentinel lymph node (SLN) in cutaneous melanoma, which can arise in a wide variety of sites throughout th...

journal_title：International journal of clinical oncology

authors： Namikawa K,Tsutsumida A,Tanaka R,Kato J,Yamazaki N

更新日期：2014-02-01 00:00:00

abstract：:In Japan, the first actual survey of morbidity from cancer was conducted by Dr. Mitsuo Segi in Miyagi Prefecture from 1951 to 1953. Population-based cancer registries were started in 1957 in Hiroshima and 1958 in Nagasaki for the follow-up of survivors of the atomic bombings. Public population-based cancer registries,...

journal_title：International journal of clinical oncology

authors： Okamoto N

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Radiofrequency ablation (RFA) can be a minimally invasive therapeutic option in patients with lung metastasis from colorectal caner. We aimed to elucidate the safety and survival benefit of computed tomography (CT)-guided percutaneous RFA for lung metastasis from colorectal cancer. METHODS:A total 188 lesio...

journal_title：International journal of clinical oncology

authors： Hiyoshi Y,Miyamoto Y,Kiyozumi Y,Sawayama H,Eto K,Nagai Y,Iwatsuki M,Iwagami S,Baba Y,Yoshida N,Kawanaka K,Yamashita Y,Baba H

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:We evaluated clinical outcomes of region target focal therapy with high-intensity focused ultrasound (HIFU) for the localized prostate cancer (PCa) based on magnetic resonance imaging-based biopsy and systematic prostate biopsy for Asian. METHODS:We prospectively recruited patients with localized PCa, locat...

journal_title：International journal of clinical oncology

authors： Shoji S,Hiraiwa S,Uemura K,Nitta M,Hasegawa M,Kawamura Y,Hashida K,Hasebe T,Tajiri T,Miyajima A

更新日期：2020-10-01 00:00:00

abstract：:Standard definitive radiotherapy for cervical cancer consists of whole pelvic external beam radiotherapy (EBRT) and intracavitary brachytherapy (ICBT). In Japan, high-dose-rate ICBT (HDR-ICBT) has been utilized in clinical practice for more than 40 years. Several randomized clinical trials demonstrated that HDR-ICBT a...

journal_title：International journal of clinical oncology

authors： Toita T

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Evaluation of the prognosis in patients with spinal metastases is important in decision making regarding surgical treatment. The purpose of this study was to investigate overall survival in patients with spinal metastases from lung cancer by histological subtype, and to investigate prognostic factors in pati...

journal_title：International journal of clinical oncology

authors： Dohzono S,Sasaoka R,Takamatsu K,Nakamura H

更新日期：2017-08-01 00:00:00

abstract：:Pseudoaneurysm complicating osteochondroma is extremely rare. We describe a pseudoaneurysm in the popliteal fossa of a 21-year-old man, occurring 5 years after apparently incomplete resection of an osteochondroma at that site. We found magnetic resonance imaging and magnetic resonance angiography to be of great diagno...

journal_title：International journal of clinical oncology

authors： Otsuka T,Yonezawa M,Kamiyama F,Matusita Y,Matui N

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the prognostic role of the pretreatment neutrophil-to-lymphocyte ratio (NLR) as a predictive marker prior to treatment of cervical cancer with radiation therapy (RT) alone or concurrent chemoradiation therapy (CCRT). METHODS:Fifty-six patients with squamous cell carc...

journal_title：International journal of clinical oncology

authors： Mizunuma M,Yokoyama Y,Futagami M,Aoki M,Takai Y,Mizunuma H

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:Boron neutron capture therapy (BNCT) is among the radiation treatments known to have a selective lethal effect on tumor cells. This study summarizes the tumor responses and the acute and late adverse effects of BNCT in the treatment of patients with both recurrent and newly diagnosed T4 salivary gland carcinoma...

journal_title：International journal of clinical oncology

authors： Aihara T,Morita N,Kamitani N,Kumada H,Ono K,Hiratsuka J,Harada T

更新日期：2014-01-01 00:00:00

abstract：:The application of prostate-specific antigen (PSA) in prostate cancer (PC) screening, diagnosis, and prognosis has improved the clinical management of PC patients. However, the PSA assay has been faced with criticism due to its potential association with over-diagnosis and subsequent overtreatment of patients with ind...

journal_title：International journal of clinical oncology

authors： Hatakeyama S,Yoneyama T,Tobisawa Y,Ohyama C

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The efficacy of individual chemotherapy based on chemosensitivity has scarcely been studied. METHODS:We examined the chemosensitivites for four anticancer agents - 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3 (2-chloroethyl)-3-nitrosourea hydrochloride (ACNU), carboplatin, cisplatin, and etoposide - of 43 ma...

journal_title：International journal of clinical oncology

authors： Ono A,Kanno H,Hayashi A,Nishimura S,Kyuma Y,Sato H,Ito S,Shimizu N,Chang CC,Gondo G,Yamamoto I,Sasaki T,Tanaka M

更新日期：2007-04-01 00:00:00

abstract：:We report a patient with avascular necrosis of the bilateral femoral head resulting from long-term steroid administration for radiation pneumonitis that occurred after tangential irradiation of the breast. The patient was a 50-year-old postmenopausal woman with breast cancer, stage IIIB (T4bN0M0) in the right C area. ...

journal_title：International journal of clinical oncology

authors： Kosaka Y,Mitsumori M,Araki N,Yamauchi C,Nagata Y,Hiraoka M,Kodama H

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:The activity and synergy for the combination treatment of cisplatin and gemcitabine has been identified in a variety of human tumor cells, including ovarian cancer cells, and has been widely approved for the treatment of non-small cell lung cancer, pancreatic cancer and biliary tract cancer. As the gastroint...

journal_title：International journal of clinical oncology

authors： Tomita Y,Saito T,Okadome M,Eto T,Ariyoshi K,Shimamoto K

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Intrahepatic cholangiocarcinoma (IHCC) has a poor prognosis, and surgery remains the only effective treatment. However, tumor recurrence after primary hepatectomy is common. We examined the significance of repeat surgery for IHCC. METHODS:We collected data for all patients with IHCC between 1992 and 2018 (n...

journal_title：International journal of clinical oncology

authors： Tokuda K,Morine Y,Saito Y,Yamada S,Miyazaki K,Yamashita S,Okikawa S,Ikemoto T,Imura S,Shimada M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:To evaluate the survival benefit of gemcitabine and paclitaxel (GT) chemotherapy for patients with metastatic urothelial cancer (UC), a retrospective analysis was performed to compare the overall survival in two periods: before (group I) and after (group II) the introduction of GT chemotherapy. PATIENTS AND...

journal_title：International journal of clinical oncology

authors： Matsui Y,Nishiyama H,Yoshimura K,Xing ND,Sumiyoshi T,Saito R,Inoue T,Kamba T,Ogawa O

更新日期：2013-04-01 00:00:00

abstract：:Primary sarcoma of the fallopian tube is a very rare neoplasm. We report the case of a 69-year-old woman affected with leiomyosarcoma of the left fallopian tube. Her chief complaint was lower abdominal pain. The preoperative diagnosis was a left adnexal malignant tumor based on pelvic examination, abdominal computed t...

journal_title：International journal of clinical oncology

authors： Ueda T,Emoto M,Fukuoka M,Miyahara D,Horiuchi S,Tsujioka H,Kawarabayashi T

更新日期：2010-04-01 00:00:00

abstract：:Juvenile granulosa cell tumor (GCT) is a rare tumor, and the majority (90%) are reported in the prepubertal or under-30-year age group, in contrast to the adult type, which is more common in the fifth decade. On histopathological examination, juvenile GCTs are distinct from the adult type of GCT, and have a lower risk...

journal_title：International journal of clinical oncology

authors： Kaur H,Bagga R,Saha SC,Gainder S,Srinivasan R,Adhya AK,Dhaliwal LK

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:We retrospectively investigated the efficacy and safety profile of weekly low-dose docetaxel (DTX) with estramustine in comparison with triweekly standard-dose DTX treatment for Japanese patients with castration-resistant prostate cancer (CRPC). METHODS:Between April 2002 and January 2011, 75 CRPC patients ...

journal_title：International journal of clinical oncology

authors： Nakai Y,Nishimura K,Nakayama M,Uemura M,Takayama H,Nonomura N,Tsujimura A,Osaka CRPC Clinical Study Collaboration.

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Zoledronic acid treatment reduces the incidence of skeletal-related events (SREs) in patients with bone metastases from breast, lung, and urologic cancers including prostate and renal cancer. The aim of this study was to evaluate the effect of zoledronic acid on SREs in patients with bone metastases from bla...

journal_title：International journal of clinical oncology

authors： Zaghloul MS,Boutrus R,El-Hossieny H,Kader YA,El-Attar I,Nazmy M

更新日期：2010-08-01 00:00:00

abstract：:When total mesorectal excision (TME) is accurately performed, dysfunction, theoretically, does not occur. However, there are differences among individuals in the running patterns and the volumes of nerve fibers, and if obesity or a narrow pelvis is present, nerve identification is difficult. Currently, the rate of uri...

journal_title：International journal of clinical oncology

authors： Moriya Y

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Testicular cancer is a rare type of cancer in males. Since the disease is seen in young men and long-term survival is ensured following a high treatment success rate, fertility in testicular cancer patients is much more important. Prior to commencement of cancer treatment, patients are given counselling with...

journal_title：International journal of clinical oncology

authors： Uçar MA,Arikan F,Coşkun HŞ,Kondak Y,Tatlı AM,Göksu SS

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Neoadjuvant cisplatin-based chemotherapy for patients with muscle-invasive bladder cancer (BC) has better survival benefit than radical cystectomy (RC) alone. However, optimal dosing schedule, including drug selection, number of cycles, and interval between chemotherapy and cystectomy, as well as acceptable ...

journal_title：International journal of clinical oncology

authors： Koie T,Ohyama C,Hashimoto Y,Hatakeyama S,Yamamoto H,Yoneyama T,Kamimura N

更新日期：2013-08-01 00:00:00

abstract：:We report the case of a 37-year-old Japanese man who presented with a left lower abdominal mass that was initially interpreted clinically as an inguinal hernia. The patient reported a swelling in his left lower abdomen over the past 6 months. Magnetic resonance imaging revealed a left inguinal mass extending from the ...

journal_title：International journal of clinical oncology

authors： Minagawa T,Matsushita K,Shimada R,Takayama H,Hiraga R,Uehara T,Murata Y

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Residual cancer burden or Ki67 expression levels in residual tumors reportedly provided significant prognostic information for a non-pathological complete response subset after neoadjuvant chemotherapy (NAC). However, the significance of Ki67 reduction for clinical response during chemotherapy in each subtyp...

journal_title：International journal of clinical oncology

authors： Enomoto Y,Morimoto T,Nishimukai A,Higuchi T,Yanai A,Miyagawa Y,Murase K,Imamura M,Takatsuka Y,Nomura T,Takeda M,Watanabe T,Hirota S,Miyoshi Y

更新日期：2016-04-01 00:00:00

abstract：:Sarcomas represent a rare and heterogeneous disease and the prognosis of patients remains poor, with a disease-free survival at 5 years of less than 10%. Only a few chemotherapeutic agents, such as doxorubicin and ifosfamide, have been identified to be active with response rates above 20%. The concept of angiostatic t...

journal_title：International journal of clinical oncology

authors： Kasper B,Ho AD,Egerer G

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Trachelectomy was developed as a fertility-sparing surgery for early-stage cervical cancer in patients of childbearing age. The purpose of this study is to evaluate oncologic and obstetric outcomes and complications after abdominal trachelectomy. METHODS:We began to perform abdominal trachelectomy in 2005. ...

journal_title：International journal of clinical oncology

authors： Okugawa K,Kobayashi H,Sonoda K,Kaneki E,Kawano Y,Hidaka N,Egashira K,Fujita Y,Yahata H,Kato K

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Japanese physicians' attitudes regarding the education of nurse practitioners (NPs) are not well described. PARTICIPANTS AND METHODS:A survey was mailed to 1,094 board members of the Japanese Society of Clinical Oncology (JSCO) and the Japanese Primary Care Association (JPCA), and the directors of the clini...

journal_title：International journal of clinical oncology

authors： Ishida Y,Hatao M,Fukushima O,Mori M,Isozaki F,Okuyama A

更新日期：2013-10-01 00:00:00

abstract：:We report four patients with hepatocellular carcinoma (all men, with liver cirrhosis and hepatitis C virus infections) who showed spontaneous regression of the tumor. When the spontaneous regression occurred all of the patients were over age 67 years. They showed a rapid increase of serum alpha-fetoprotein levels just...

journal_title：International journal of clinical oncology

authors： Kondo S,Okusaka T,Ueno H,Ikeda M,Morizane C

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:The aim of this phase II study was to evaluate the feasibility and safety of a carboplatin and gemcitabine combination regimen in the treatment of completely resected non-small cell lung cancer (NSCLC). METHODS:Patients with completely resected pathologically documented stage IB, II or IIIA NSCLC were treat...

journal_title：International journal of clinical oncology

authors： Usami N,Yokoi K,Hasegawa Y,Taniguchi H,Shindo J,Yamamoto M,Suzuki R,Imaizumi K,Kondo M,Shimokata K,Central Japan Lung Study Group.

更新日期：2010-12-01 00:00:00