Abstract:
BACKGROUND:Radiofrequency ablation (RFA) can be a minimally invasive therapeutic option in patients with lung metastasis from colorectal caner. We aimed to elucidate the safety and survival benefit of computed tomography (CT)-guided percutaneous RFA for lung metastasis from colorectal cancer. METHODS:A total 188 lesions were ablated in 43 patients from 2005 to 2017. The clinicopathological and survival data of patients were collected retrospectively. The short- and long-term outcomes and prognostic factors were analyzed. RESULTS:Eight patients (18.6%) had viable extrapulmonary metastasis at RFA treatment. The median number of treated lung tumors was 2, and the median maximum diameter was 12 mm. Complications, such as pneumothorax, pleural effusion and subcutaneous emphysema, occurred in 24 (55.8%) patients. Although chest tube drainage for pneumothorax was needed in 6 patients (14.0%), there were no mortalities. Repeated RFA for lung recurrence after primary RFA was performed in 14 patients (32.6%). In a median follow-up of 24.3 months, the median progression-free and overall survival (OS) were 6.8 months and 52.7 months, respectively. The presence of extrapulmonary metastasis and a maximum tumors size of > 15 mm were independently associated with a worse disease-free survival and OS. The OS of patients who underwent repeated RFA was significantly better than that of patients who underwent RFA only once. CONCLUSION:CT-guided percutaneous RFA for lung metastasis from colorectal cancer is a safe and effective procedure in patients not eligible for surgery, particularly for lesions smaller than 1.5 cm without extrapulmonary metastasis.
journal_name
Int J Clin Oncoljournal_title
International journal of clinical oncologyauthors
Hiyoshi Y,Miyamoto Y,Kiyozumi Y,Sawayama H,Eto K,Nagai Y,Iwatsuki M,Iwagami S,Baba Y,Yoshida N,Kawanaka K,Yamashita Y,Baba Hdoi
10.1007/s10147-018-1357-5subject
Has Abstractpub_date
2019-03-01 00:00:00pages
288-295issue
3eissn
1341-9625issn
1437-7772pii
10.1007/s10147-018-1357-5journal_volume
24pub_type
临床试验,杂志文章abstract::We report the case of a 65-year-old man with recurrent prostate cancer who presented with meningeal carcinomatosis. In September 2007, he had been diagnosed with mixed type small cell carcinoma and adenocarcinoma at clinical stage T4N1M1 (primary prostate tumor with multiple bone, liver, and lymph node metastases) and...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-008-0869-9
更新日期:2009-10-01 00:00:00
abstract::Distant metastasis from colorectal carcinoma most often occurs in the liver and lungs. Metastasis to bones, adrenals, lymph nodes, brain, and skin has also been reported. Metastatic colorectal carcinoma to the testes is very uncommon. Even more uncommon is testicular metastasis from rectal carcinoma. Researchers throu...
journal_title:International journal of clinical oncology
pub_type: 杂志文章,评审
doi:10.1007/s10147-010-0140-z
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Several factors related to the immune system, such as a history of allergies and virus infections, may be associated with acute lymphoblastic leukemia (ALL). The purpose of this study was to analyze whether the presence of atopic diseases and previous infection with parvovirus B19 and Epstein-Barr virus (EBV...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-016-0988-7
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:When soft-tissue sarcomas occur near neurovascular structures, preoperative images cannot always reveal the accurate relationship between the tumor and these structures. Therefore, in some patients, neurovascular structures are sacrificed unnecessarily. In other patients, neurovascular structures are preserv...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s101470200006
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:Cesarean radical hysterectomy (CRH) for invasive cervical cancer during pregnancy is characterized by heavy blood loss. Any surgical modifications made in an attempt to reduce the blood loss are valuable. Our study was designed to evaluate the efficacy of amputating the uterine corpus during CRH. METHODS:All...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-009-0014-4
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Intravesical recurrence (IVR) after radical nephroureterectomy (RNU) for urothelial carcinoma of the upper urinary tract (UCUUT) is common. One of the mechanisms driving this is the implantation of cancer cells from the UCUUT at the RNUs. Therefore, their detection after RNU can assist in predicting IVR. Thi...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-020-01785-9
更新日期:2021-01-01 00:00:00
abstract::We report four patients with pancreatic metastasis of renal cell carcinoma who were successfully treated with radiation therapy. The patients were one woman and three men with a median age of 55 years (range, 49 to 62 years) who underwent radical nephrectomy for primary renal cell carcinoma. The median interval from n...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-008-0833-8
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:In treatment of locally advanced squamous cell carcinoma of the head and neck (SCCHN), the use of docetaxel, cisplatin, and 5-fluorouracil (TPF) followed by high-dose cisplatin chemoradiotherapy (CRT) carries concerns over toxicity. We evaluated the feasibility of TPF as induction chemotherapy (IC) to Japane...
journal_title:International journal of clinical oncology
pub_type: 临床试验,杂志文章
doi:10.1007/s10147-019-01418-w
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:The use of adjuvant treatment has not been sufficiently investigated in duodenal adenocarcinoma. This study evaluated the effect of postoperative radiotherapy (PORT) on survival outcomes in this rare malignancy. METHODS:We identified patients who were diagnosed between 2004 and 2013 in the Surveillance, Epidem...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-017-1226-7
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:High-risk factors for recurrence of head and neck squamous cell carcinoma after surgical resection include involvement of ≥ 2 regional lymph nodes, extracapsular spread, and microscopic involvement of resected mucosal margins. Adjuvant chemoradiotherapy is thought to improve postoperative locoregional contro...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-013-0532-y
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Previous reports concerning the prevalence of human papillomavirus (HPV) in oral squamous cell carcinoma (OSCC) have observed varied results. The aim of this study was to evaluate the prevalence of HPV in oral premalignant lesions (OPL) and OSCC. For accurate HPV detection in oral lesions, comparative analys...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-011-0236-0
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:The purpose of this study was to determine if quantitative SUV-related, volumetric FDG PET parameters, and texture features (SPs, VPs, and TFs, respectively) were useful to evaluate and predict response and recurrence after chemotherapy in follicular lymphoma (FL). METHODS:Pre- and posttreatment FDG PET examin...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-019-01482-2
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:This multi-center, phase III trial assesses the efficacy of daikenchuto (TU-100) on gastrointestinal disorders after hepatic resection (UMIN Registration No. 000003103). MATERIALS AND METHODS:A total of 231 patients, who underwent hepatic resection at 26 Japanese centers, were enrolled. Patients were random...
journal_title:International journal of clinical oncology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s10147-014-0678-2
更新日期:2015-02-01 00:00:00
abstract::A 32-year-old Japanese woman was diagnosed as having stage Ib1 adenocarcinoma by diagnostic laser conization at a local hospital. She was admitted to our hospital for fertility-sparing treatment. A radical trachelectomy (RT) was performed using the laparoscopic vaginal procedure. The procedure was started with a lapar...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-005-0536-3
更新日期:2006-04-01 00:00:00
abstract::Complex carbohydrates are major components of the cell membrane and they play crucial roles in cell-cell and cell-extracellular matrix interactions, as well as in signal transduction. They consist of three kinds of molecular species; glycoproteins, proteoglycans, and glycosphingolipids. There is a distinct difference ...
journal_title:International journal of clinical oncology
pub_type: 杂志文章,评审
doi:10.1007/s10147-008-0809-8
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:No investigation of S-1 monotherapy in previously treated advanced non-small-cell lung cancer (NSCLC) patients has yet been reported. We conducted a retrospective study to evaluate the efficacy and tolerability of S-1 in patients with failure of second- or further-line chemotherapy. PATIENTS AND METHODS:The...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-010-0034-0
更新日期:2010-04-01 00:00:00
abstract::Despite major improvements in the treatment of early-stage breast cancer over the past 15 years, many controversies exist surrounding the optimal adjuvant therapies for these patients. Adjuvant chemotherapy has been demonstrated to reduce recurrence and improve mortality, but questions persist as to what is the optima...
journal_title:International journal of clinical oncology
pub_type: 杂志文章,评审
doi:10.1007/s10147-003-0338-4
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:To fill the data gap between clinical trials and real-world settings, this study assessed the overall effectiveness and safety of nivolumab in patients with head and neck cancer (HNC) during Japanese real-world clinical practice. METHODS:This was a multicenter, retrospective study in Japanese patients with ...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-020-01829-0
更新日期:2020-11-21 00:00:00
abstract:BACKGROUND:Total pharyngolaryngectomy (TPL) is a conventional and standard surgical method for locoregional control of advanced hypopharyngeal cancer (HPC). This study aimed to define the clinicopathological prognostic factors of TPL by evaluating our surgical experience of TPL in the treatment of HPCs. METHODS:We ret...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-014-0709-z
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:The standard treatment for cervical cancer is chemoradiation although some patients showed treatment resistance. The purpose of this study was to investigate the clinical efficacy of surgery after chemoradiation for cervical cancer. METHODS:Patients with FIGO stage IB2 to IIB cervical cancer were included i...
journal_title:International journal of clinical oncology
pub_type: 临床试验,杂志文章
doi:10.1007/s10147-019-01551-6
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:We evaluated the association between subclinical interstitial lung disease (ILD) and fatal radiation pneumonitis (RP) in patients with thoracic tumors treated with thoracic radiotherapy (RT). METHODS:Sixty-two consecutive patients with thoracic tumors treated with thoracic RT were retrospectively analyzed. ...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-014-0679-1
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:The efficacy of direct oral anti-coagulants (DOACs) for the treatment of venous thromboembolism (VTE) in Japanese patients with advanced cancer is largely unknown. METHODS:This prospective single-center observational study enrolled Japanese patients with unresectable advanced cancer who started DOAC treatme...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-019-01415-z
更新日期:2019-07-01 00:00:00
abstract::The fourth edition of the Japan Society of Gynecologic Oncology guidelines for the treatment of ovarian cancer including primary peritoneal cancer and fallopian tube cancer was published in 2015. The guidelines contain seven chapters and six flow charts. The major changes in this new edition are as follows-(1) the for...
journal_title:International journal of clinical oncology
pub_type: 杂志文章,实务指引
doi:10.1007/s10147-016-0985-x
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:The mechanisms underlying cognitive decline after radiotherapy not directed at brain areas remains unclear. We previously suggested that adjuvant breast radiotherapy in breast conservation therapy could lower memory function soon after therapy, and that the process might be partially mediated by plasma inter...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-018-1330-3
更新日期:2019-01-01 00:00:00
abstract::Among head and neck squamous cell carcinoma (HNSCC), the incidence of oropharyngeal SCC (OPSCC) is increasing in contrast to carcinoma with origin in other subsites. Human papillomavirus (HPV) is now recognized as a significant risk factor of the carcinogenesis of OPSCC. The HPV-related OPSCC patients tend to be relat...
journal_title:International journal of clinical oncology
pub_type: 杂志文章,评审
doi:10.1007/s10147-016-1009-6
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:In patients with relapsed ovarian cancer, the objectives of salvage therapy are considered to be maintenance of quality of life and prolongation of patient survival. Chemotherapy using oral agents could be a good choice for salvage therapy. We reassessed the usefulness of oral cyclophosphamide (CPA) salvage ...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-010-0094-1
更新日期:2010-10-01 00:00:00
abstract::Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Recently, the incidence of oropharyngeal cancer (OPC) has increased markedly in comparison to that of HNSCC, which is associated with the use of tobacco or alcohol or both. This increase has resulted mainly from the global rise in...
journal_title:International journal of clinical oncology
pub_type: 杂志文章,评审
doi:10.1007/s10147-016-1005-x
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:We conducted a phase I dose escalation study to determine the maximum tolerated dose (MTD), the recommended dose (RD) and the safety profile of amrubicin (AMR) plus paclitaxel (PTX) combination regimen for patients with previously treated non-small cell lung cancer (NSCLC). PATIENTS AND METHODS:PTX was admi...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-015-0883-7
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:The efficacy of carbon-ion radiotherapy (C-ion RT) for lymph node (LN) oligo-recurrence has only been evaluated in limited single-center studies. We aimed to investigate the benefit of C-ion RT for LN oligo-recurrence in a large multi-center study. METHODS:Patients who received C-ion RT between December 199...
journal_title:International journal of clinical oncology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/s10147-019-01440-y
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Neoplastic cardiac tamponade (NCT) is a life-threatening complication of cancer. The interval between cancer diagnosis and NCT onset and the prognosis after pericardiocentesis may differ according to cancer type. METHODS AND RESULTS:We performed a retrospective study of 113 patients (54 % male) with NCT who...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
doi:10.1007/s10147-015-0794-7
更新日期:2015-10-01 00:00:00