Abstract:
OBJECTIVE:Cesarean radical hysterectomy (CRH) for invasive cervical cancer during pregnancy is characterized by heavy blood loss. Any surgical modifications made in an attempt to reduce the blood loss are valuable. Our study was designed to evaluate the efficacy of amputating the uterine corpus during CRH. METHODS:All cases of radical hysterectomy (RH) were evaluated. Cases were divided into: (a) cesarean section immediately followed by RH for invasive cervical cancer complicating pregnancy (CRH group); and (b) RH for nonpregnant subjects (RH group). The information abstracted included estimated blood loss (EBL), operative time, intraoperative transfusion, and use of amputation of uterine corpus during CRH. Nonparametric tests were used for the statistical analysis. RESULTS:There were five CRH cases (3 for CRH with amputation, 2 for CRH without amputation) and 209 RH cases were evaluated for statistics during the study period. The difference in mean operative time between the CRH group and the RH group was not statistically significant: 276.6 min (range 160-425) versus 297.3 min (range 147-645), p = 0.66. The mean EBL for the CRH group was significantly larger than that for the RH group: 2106.6 ml (range 730-4150) versus 858.8 ml (range 150-4770), p < 0.001. Mean operative time and mean EBL for CRH with amputation of uterine corpus were significantly less than those for CRH without amputation of uterine corpus: operative time, 186.0 min (range 160-228) versus 412.5 min (range 400-425), p = 0.043; EBL, 1034.3 ml (range 730-1540) versus 3715.0 ml (range 3280-4150), p = 0.043. No intraoperative tumor exposures were observed in the amputated cases. CONCLUSION:Amputation of uterine corpus during CRH for invasive cervical cancer during pregnancy significantly improves the intraoperative performance, although it should be used with care.
journal_name
Int J Clin Oncoljournal_title
International journal of clinical oncologyauthors
Matsuo K,Enomoto T,Yamasaki Mdoi
10.1007/s10147-009-0014-4subject
Has Abstractpub_date
2010-02-01 00:00:00pages
77-81issue
1eissn
1341-9625issn
1437-7772journal_volume
15pub_type
杂志文章abstract:BACKGROUND:Sternal resection is occasionally required for patients with malignant tumors, particularly sarcomas, in the sternal region. Few reports have described post-operative respiratory and shoulder function after sternal resection for patients with bone and soft-tissue sarcomas. METHODS:Eight consecutive patients...
journal_title:International journal of clinical oncology
pub_type: 杂志文章
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journal_title:International journal of clinical oncology
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更新日期:2011-12-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,实务指引
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pub_type: 临床试验,杂志文章
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