HIV-1 Nef associates with p22-phox, a component of the NADPH oxidase protein complex.

abstract：:Mucus production by goblet cells in the gastrointestinal tract following Salmonella typhimurium infection using a ligated ileal loop model in mice was investigated. Assessment of the morphology of the loop tissue after Salmonella challenge revealed generalized tissue inflammation, characterized by edema and an inflamm...

journal_title：Cellular immunology

authors： Arnold JW,Klimpel GR,Niesel DW

更新日期：1993-10-15 00:00:00

abstract：:Human K cells are able to lyse human lymphoblastoid B cells in the presence of specific anti-human immunoglobulin isotype antibodies. The human lymphoblastoid B-cell line DAUDI (surface mu- and kappa-chains positive) was lysed in the presence of anti-mu and anti-kappa antisera, or IgG fraction of these antisera, and B...

journal_title：Cellular immunology

authors： Caraux J,Weigle WO

更新日期：1983-03-01 00:00:00

abstract：:Two interleukin-2 (IL-2)-dependent cytotoxic T-cell clones were obtained by limiting dilution from a lymphocyte culture stimulated in vitro with the autologous Epstein-Barr virus-transformed lymphoblastoid cell line (LCL) in the presence of fetal calf serum (FCS). Both clones uniformly had a T3+, T4+, Dr+ phenotype an...

journal_title：Cellular immunology

authors： Torsteinsdottir S,Masucci MG,Brautbar C,Lenoir G,Klein G,Klein E

更新日期：1986-04-01 00:00:00

abstract：:Activation of lck-fyn kinases during T cell receptor signaling leads to Vav phosphorylation, activation of downstream targets including Rac1, and a transient decline in ezrin and moesin phosphorylation. We have shown that age increases Rac1 activity and lowers ezrin and moesin phosphorylation in resting mouse CD4 cell...

journal_title：Cellular immunology

authors： Garcia GG,Miller RA

更新日期：2009-01-01 00:00:00

abstract：:The functional specificity of three types of macrophage chemotactic factors ( MCFs ), -a, -b, and -c, from purified protein derivative of tuberculin (PPD)-induced delayed hypersensitivity reaction (DHR) skin sites on guinea pigs, was analyzed using macrophage cell line cells, M1, established from myeloid leukemia cell...

journal_title：Cellular immunology

authors： Honda M,Masuda T,Yoshimura T,Hayashi H

更新日期：1984-06-01 00:00:00

abstract：:Macrophages are key cell types of innate immunity and play a central role in inflammation and host defense. Leukocyte-associated Ig-like receptor-1 (LAIR-1) is highly expressed on macrophages and regulates macrophage functions in several conditions. However, whether LAIR-1 is involved in governing macrophage polarizat...

journal_title：Cellular immunology

authors： Jin J,Wang Y,Ma Q,Wang N,Guo W,Jin B,Fang L,Chen L

更新日期：2018-09-01 00:00:00

abstract：:Several studies have demonstrated that addition of soluble anti-CD6 mAbs to 12-O-tetradecanoylphorbol 13-acetate (TPA)-treated naive T cells can induce cell proliferation. We showed in the present study that cell proliferation in TPA-treated T cell cultures can be enhanced several fold when the anti-CD6 mAbs are eithe...

journal_title：Cellular immunology

authors： Osorio LM,Ordonez C,Garcia CA,Jondal M,Chow SC

更新日期：1995-11-01 00:00:00

abstract：:The pim-1 gene encodes a serine/threonine protein kinase with expression restricted primarily to cells of hematopoietic lineage and is thought to play a role in the signal transduction events associated with lymphocyte activation. A rapid increase in pim-1 mRNA levels was found after stimulation of normal unseparated ...

journal_title：Cellular immunology

authors： Wingett D,Stone D,Davis WC,Magnuson NS

更新日期：1995-04-15 00:00:00

abstract：:Adenomatous polyposis coli (APC) functions are involved in the heterotypic interactions occurring between intestinal epithelial cells (IECs) and intra-epithelial lymphocytes (IELs). These interactions may be of interest in cancer prevention, since recent data provide evidence for lymphocyte mediated immunosurveillance...

journal_title：Cellular immunology

authors： Forest V,Pierre F,Bassonga E,Meflah K,Olivier C,Menanteau J

更新日期：2003-05-01 00:00:00

abstract：:Two monoclonal antibodies specific for different rat T-cell subpopulations, the anti-helper-T-cell antibody, W3/25, and the OX8 suppressor cell antibody were used to investigate lectin-stimulated T-lymphocyte differentiation of F-344 rat bone marrow cells in culture. Cytofluorometric analysis of freshly isolated lymph...

journal_title：Cellular immunology

authors： Pfeifer RW,Stillman WS,Irons RD

更新日期：1983-12-01 00:00:00

abstract：:We have systematically studied uncloned human cell lines derived from anti-influenza A virus or anti-Epstein-Barr virus (EBV) bulk cultures, or from cultures highly enriched for CD4+ or CD8+ lymphocytes. The most noteworthy results are the following: (1) Anti-viral bulk cultures consisted of more than 90% of CD8+ cell...

journal_title：Cellular immunology

authors： Gomez A,Bourgault I,Gomard E,Picard F,Levy JP

更新日期：1989-02-01 00:00:00

abstract：PURPOSE:We aim to evaluate the effects of atorvastatin on the expression of Toll-like receptor (TLR4) protein and mRNA, and to explore their effects on TLR4-dependent downstream signaling in human monocytic leukemia (THP-1) cells. METHODS:TLR4 protein and mRNA expression, levels of NF-κB protein, and expression of TNF...

journal_title：Cellular immunology

authors： Yang SS,Li R,Qu X,Fang W,Quan Z

更新日期：2012-09-01 00:00:00

abstract：:This study was conducted to investigate the effects of sex hormones upon the nature of soluble immune response suppressor (SIRS) produced by concanavalin A-stimulated Lyt-2+ T cells. Conventional SIRS affected IgM PFC only. However, SIRS made with progesterone (20-400 ng/ml or Prog-SIRS) suppressed IgM PFC, one-way ML...

journal_title：Cellular immunology

authors： Kita E,Hamuro A,Oku D,Nishikawa F,Yasui K,Emoto M,Katsui N,Kashiba S

更新日期：1990-10-01 00:00:00

abstract：:Abnormalities in immune response play a major role in the increased susceptibility to infection after hemorrhage and trauma. Infections occurring after injury often originate in the intestine. In order to determine the effects of hemorrhage on intestinal B cell function, we examined hemorrhage-induced alterations in a...

journal_title：Cellular immunology

authors： Abraham E,Chang YH

更新日期：1990-06-01 00:00:00

abstract：:The effects of oral administration of methylated bovine serum albumin (mBSA) on antigen-induced arthritis (AIA) in rats that was induced by immunization with mBSA followed by the intraarticular injection of the same antigen were investigated. When mBSA was orally given to animals before immunization with the antigen, ...

journal_title：Cellular immunology

authors： Yoshino S

更新日期：1995-06-01 00:00:00

abstract：:As an atypical guanine nucleotide exchange factor (GEF), Dock5 has been extensively studied in cellular functions. However, the role of Dock5 on B-cell immunity still remain elusive. In this study, we generated a Dock5 knockout mouse model to study the effect of Dock5 deficiency on B cell development, differentiation ...

journal_title：Cellular immunology

authors： Chen A,Yang D,Xuan X,Miller H,Luo X,Yu J,Yang G,Wang H,Liu C

更新日期：2019-03-01 00:00:00

abstract：:Stimulation via the CD3/TCR molecular complex induces proliferation of resting T cells, but triggers programmed cell death (apoptosis) in immature thymocytes and preactivated mature T cells. Activation-induced cell death (AICD) triggered by anti-CD3/TCR mAb or by staphylococcus enterotoxin superantigen is associated w...

journal_title：Cellular immunology

authors： Pohl T,Pechhold K,Oberg HH,Wilbert OM,Kabelitz D

更新日期：1995-12-01 00:00:00

abstract：:TNF-alpha plays an important role in the development of secondary lymphoid tissues. Earlier studies showed that fibroblastic reticular cells express TNF-alpha receptor, suggesting that TNF-alpha may affect the development of FRCs. To test this, we analyzed the development and function of FRCs in wild-type or TNF-alpha...

journal_title：Cellular immunology

authors： Zhao L,Chen J,Liu L,Gao J,Guo B,Zhu B

更新日期：2015-02-01 00:00:00

abstract：:Thymic (T) or bursal (B) lymphocytes from chicks sensitized to Mycobacterium tuberculosis produce an avian lymphocyte inhibitory factor (LyIF). The physiochemical properties of both T and B LyIF were established by ultrafiltration which yielded four fractions with molecular weight ranges of greater than 100,000; 50,00...

journal_title：Cellular immunology

authors： Martin DE,Glick B

更新日期：1983-07-15 00:00:00

abstract：:Purified monomorphic monoclonal antibodies against Class I and Class II antigens in the inhibition of in vitro allogenic response were assayed. As expected, anti-Class II antibodies are highly inhibitory when used in concentrations greater than 5 micrograms/ml in MLRI and 50 micrograms/ml in MLRII. Surprisingly, anti-...

journal_title：Cellular immunology

authors： Kalil J,Wollman EE

更新日期：1983-07-15 00:00:00

abstract：:This paper investigates the presence of HLA class I-restricted and tumor-specific cytotoxic T lymphocytes (CTL) in tumor sites of esophageal cancers. Five CTL lines were established from the metastatic lymph nodes or pleural effusion by incubation with interleukin-2 of tumor-infiltrating lymphocytes: cases 1 and 5, HL...

journal_title：Cellular immunology

authors： Toh U,Yamana H,Nakao M,Imai Y,Seki N,Takasu H,Kaneshige T,Fujita H,Shirouzu K,Itoh K

更新日期：1997-05-01 00:00:00

abstract：:The expression and function of surface immunoglobulin (sIg) receptors was analyzed using antigen-specific monoclonal B cells and T cells. When B cells were incubated with antigen (hapten carrier), hapten-specific sIg receptor expression was greatly reduced. The specific antigen-presentation activity of the B cells was...

journal_title：Cellular immunology

authors： Watanabe M,Watts TH,Gariepy J,Hozumi N

更新日期：1988-03-01 00:00:00

abstract：:Phagocytosis of pathogens by macrophages is crucial for the successful resolution of inflammation induced by microbial infection. Taurine chloramine (TauCl), an endogenous anti-inflammatory and antioxidative substance, is produced by reaction between taurine and hypochlorous acid by myeloperoxidase activity in neutrop...

journal_title：Cellular immunology

authors： Kim W,Kim SH,Jang JH,Kim C,Kim K,Suh YG,Joe Y,Chung HT,Cha YN,Surh YJ

更新日期：2018-05-01 00:00:00

abstract：:Six OKT4+ human T-cell lines that require continuing PHA stimulation and TCGF for continuous growth were established. The cells from all six of these T-cell lines became smaller in size and lost the cell surface Ia antigen when they were grown in phytohemagglutinin (PHA)-depleted growth factor. These cells were unable...

journal_title：Cellular immunology

authors： Tsui F,Underdown BJ,Klein M,Zimmerman B

更新日期：1984-04-15 00:00:00

abstract：:PNK-E and G7 mAbs regulate porcine NK and ADCC activities by binding to distinct NK function-associated trigger molecules on porcine NK cells. Previous work demonstrates that PNK-E mAb binds to a 205-kDa tetrameric molecule composed of two 47-kDa peptides and two 50-kDa peptides and G7 mAb binds to a distinct 40-kDa h...

journal_title：Cellular immunology

authors： Wierda WG,Johnson BD,Dato ME,Kim YB

更新日期：1993-02-01 00:00:00

abstract：:A low culture temperature of 27 degrees C inhibited mouse primary in vitro anti-hapten plaque-forming cell responses to a thymus-dependent (TD) antigen (Ag) (trinitrophenyl-keyhole limpet hemocyanin, TNP-KLH). In contrast, the magnitudes of secondary responses to TNP-KLH or primary responses to a thymus-independent (T...

journal_title：Cellular immunology

authors： Wang-Yang MC,Buttke TM,Miller NW,Clem LW

更新日期：1990-04-01 00:00:00

abstract：:The cytokine interleukin 6 (IL-6) has been shown to have multiple biological activities against many cellular targets. The present studies were designed to determine whether these activities extended to the neutrophil (PMN). Initially, we investigated the ability of IL-6 to modulate PMN-mediated antibody-dependent cel...

journal_title：Cellular immunology

authors： Borish L,Rosenbaum R,Albury L,Clark S

更新日期：1989-07-01 00:00:00

abstract：:Previous studies have validated the capacity of classical (HLA-A,B,C) and nonclassical (HLA-G) MHC class I antigens expressed by target cells to influence natural killer (NK) cell-mediated cytolysis. Generally, elevated expression of these HLA class I molecules is correlated with enhanced resistance to lysis by NK cel...

journal_title：Cellular immunology

authors： Storkus WJ,Wei M,Cresswell P,Dawson JR

更新日期：1996-01-10 00:00:00

abstract：:A new mechanism for regulation of delayed-type hypersensitivity (DTH) was investigated. The subcutaneous injection without adjuvant of syngeneic epidermal Langerhans' cells (LC) pulsed with keyhole limpet hemocyanin (KLH) into BALB/c mice gave rise to DTH upon challenge of the ear with the same antigen. When such cell...

journal_title：Cellular immunology

authors： Morikawa Y,Furotani M,Matsuura N,Kakudo K

更新日期：1993-11-01 00:00:00

abstract：:BENTA (B cell Expansion with NF-κB and T cell Anergy) is a novel lymphoproliferative disorder caused by germline, gain-of-function (GOF) mutations in the lymphocyte-restricted scaffolding protein CARD11. Similar somatic CARD11 mutations are found in lymphoid malignancies such as diffuse large B cell lymphoma (DLBCL). ...

journal_title：Cellular immunology

authors： Stinson JR,Dorjbal B,McDaniel DP,David L,Wu H,Snow AL

更新日期：2020-07-01 00:00:00