Abstract:
:New hetero(micro(3)-oxo)trinuclear iron(III) furoates with the general formulas [Fe(2)MO(alpha-Fur)(6)(L)(H(2)O)(2)], where L = THF (1-3), DMF (4-5), M = Mn(2+) (1, 4), Co(2+) (2, 5), Ni(2+) (3, 6) and [Fe(2)MO(alpha-Fur)(6)(3Cl-Py)(3)], where M = Mn(2+) (7), Co(2+) (8), Ni(2+) (9); have been synthesised and investigated by Mössbauer and IR spectroscopies. The X-ray crystal structure has been determined for the 4 and 8 complexes, indicating that they are related to the monoclinic crystal system (P2(1)/n) and have a structure typical of mu(3)-O-bridged trinuclear iron (III) compounds. The (57)Fe Mössbauer spectra of microcrystalline samples of the compounds indicate the presence of high-spin iron (III) (S = 5/2) with a near symmetrical environments. The iron(III)-cobalt(II) containing compounds 2, 5 and 8 displayed MIC values between 0.83 / 4.00 microg/mL.
journal_name
Eur J Med Chemjournal_title
European journal of medicinal chemistryauthors
Melnic S,Prodius D,Stoeckli-Evans H,Shova S,Turta Cdoi
10.1016/j.ejmech.2009.12.053subject
Has Abstractpub_date
2010-04-01 00:00:00pages
1465-9issue
4eissn
0223-5234issn
1768-3254pii
S0223-5234(10)00019-Xjournal_volume
45pub_type
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