Chemotherapy of leishmaniasis part III: synthesis and bioevaluation of novel aryl substituted terpenyl pyrimidines as antileishmanial agents.

Abstract:

:Some aryl substituted terpenyl pyrimidines 4 (a-p) have been synthesized using novel synthetic methods. The compounds were screened for in vitro antileishmanial activity against promastigotes. Compounds 4c, 4i and 4l showed IC(50) values as 35, 35 and 25 microg ml(-1).

journal_name

Eur J Med Chem

authors

Chandra N,Pandey S,Ramesh,Suryawanshi SN,Gupta S

doi

10.1016/j.ejmech.2006.02.004

subject

Has Abstract

pub_date

2006-06-01 00:00:00

pages

779-85

issue

6

eissn

0223-5234

issn

1768-3254

pii

S0223-5234(06)00075-4

journal_volume

41

pub_type

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