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Synthesis of indazole motifs and their medicinal importance: an overview.

Abstract：

:Indazoles is an important class of heterocyclic compounds having a wide range of biological and pharmaceutical applications. There is enormous potential in the synthesis of novel heterocyclic systems to be used as building blocks for the next generation of pharmaceuticals as anti-bacterial, anti-depressant and anti-inflammatory. Fused aromatic 1H and 2H-indazoles are well recognized for anti-hypertensive and anti-cancer properties. The present review focuses on novel routes of their synthesis and various biological activities.

journal_name

Eur J Med Chem

journal_title

European journal of medicinal chemistry

authors

Gaikwad DD,Chapolikar AD,Devkate CG,Warad KD,Tayade AP,Pawar RP,Domb AJ

doi

10.1016/j.ejmech.2014.11.029

subject

Has Abstract

pub_date

2015-01-27 00:00:00

pages

707-31

eissn

0223-5234

issn

1768-3254

pii

S0223-5234(14)01061-7

journal_volume

90

pub_type

杂志文章,评审

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