Abstract:
:Determining the order of events is essential for accurate memory recollection: an ability previously linked to both frontal and medial temporal functioning. Frontal-subcortical and medial temporal dysfunction typify vascular dementia (VaD) and Alzheimer's disease (AD), respectively. Therefore, we assessed patients' ordering abilities using a novel sequencing task that progressively increased memory load. VaD patients made more errors and selected more previously encountered stimuli than did AD. Curve analysis revealed a general decline in ordering for VaD whereas error production in AD is more dependent on memory load. These findings generally support the role of frontal-subcortical functioning in temporal order memory.
journal_name
J Clin Exp Neuropsycholjournal_title
Journal of clinical and experimental neuropsychologyauthors
Hampstead BM,Libon DJ,Moelter ST,Swirsky-Sacchetti T,Scheffer L,Platek SM,Chute Ddoi
10.1080/13803390903418918subject
Has Abstractpub_date
2010-07-01 00:00:00pages
645-54issue
6eissn
1380-3395issn
1744-411Xpii
918677255journal_volume
32pub_type
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