Abstract:
:Neurobehavioral impairments are frequently reported following treatment for childhood cancers, with cranial irradiation (CRT). This study investigated attention and information processing skills, predicting that these skills would be impaired due to the vulnerability of cerebral white matter in early childhood. Three treatment groups were studied: (i) CRT+chemotherapy (n = 35); (ii) chemotherapy alone (n = 19); (iii) healthy children (n = 35). All children were aged 9 to 16 years at time of assessment, with no pre-diagnosis history of neurologic, developmental, or psychiatric disorder. Children were administered a series of task measuring processing speed and sustained, selective, and shifting attention. For children treated with CRT + chemo, results identified residual deficits in processing speed for complex tasks, selective and shifting attention. In contrast, processing speed was intact for simple tasks, and there was no clear evidence of deterioration in performance over time, as might be expected in the presence of a sustained attention deficit. Children treated with chemotherapy alone demonstrated generally intact attentional skills. However, this group did record an increasing number of attentional lapses over time on tasks tapping sustained attention skills.
journal_name
J Clin Exp Neuropsycholjournal_title
Journal of clinical and experimental neuropsychologyauthors
Anderson VA,Godber T,Smibert E,Weiskop S,Ekert Hdoi
10.1080/13803390409609792subject
Has Abstractpub_date
2004-08-01 00:00:00pages
684-97issue
5eissn
1380-3395issn
1744-411Xpii
DYFLYG8UDV9PQW95journal_volume
26pub_type
杂志文章abstract::Previous neuropsychological research suggests that psychometrically defined subclinical obsessive-compulsive (OC) individuals perform worse than non-OC controls on specific tests of executive functioning. This study aimed to extend these findings by comparing the performance of 25 subclinical OC and 28 non-OC control ...
journal_title:Journal of clinical and experimental neuropsychology
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更新日期:2003-09-01 00:00:00
abstract::Stroke disrupts motor, sensory, and cognitive systems in survivors. Unlike in physical impairments, assessment of cognitive function is often inadequate, as no standardized procedure to monitor cognitive recovery post stroke exists. We evaluated a number of novel task-orientated tools designed to assess subtle cogniti...
journal_title:Journal of clinical and experimental neuropsychology
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doi:10.1080/13803395.2012.690368
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abstract::Proficient, nonnative English-speaking neurosurgery candidates are assessed for language function in English. In order to understand whether it is necessary to also assess native-language function, we examined the influence of native language on the bilingual language network of early, proficient bilinguals using func...
journal_title:Journal of clinical and experimental neuropsychology
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abstract:INTRODUCTION:Previous studies have demonstrated that students with attention-deficit/hyperactivity disorder (ADHD) struggle particularly with grasping the implicit, inferential level of narratives that is crucial for story comprehension. However, these studies used offline tasks (i.e., after story presentation), used i...
journal_title:Journal of clinical and experimental neuropsychology
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abstract::Estimation of premorbid IQ in traumatic brain injury (TBI) is clinically and scientifically valuable because it permits the quantification of the cognitive impact of injury. This is achieved by comparing performances on tests of current ability to estimates of premorbid IQ, thereby enabling current capacity to be inte...
journal_title:Journal of clinical and experimental neuropsychology
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abstract::In attempting to memorize a sentence about an action, such as "Pick up the glass," performing the action (motor encoding) results in better memory performance than simply memorizing the words (verbal encoding). Such enhancement of memory is known as the enactment effect. Several theories have been proposed to explain ...
journal_title:Journal of clinical and experimental neuropsychology
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abstract::Tests of paced serial addition are used to detect diminished information-processing capacity. Nonetheless, performance might be influenced by modality-specific interference or by variables that specifically affect numerical processing. In a series of three experiments with normal adults, we manipulated, respectively, ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Journal of clinical and experimental neuropsychology
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doi:10.1080/13803390701380591
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abstract::To examine the progression of neuropsychologic and metabolic changes in the early stages of dementia of the Alzheimer type (DAT), we studied 11 midly demented patients longitudinally. Three aspects of neuropsychological function were measured: memory, attention to complex sets and abstract reasoning, and lateralized f...
journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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abstract:INTRODUCTION:The cognitive reserve (CR) hypothesis attempts to explain the discrepancy between brain damage and clinical manifestations in neurodegenerative diseases. Recently the concept of CR was applied to the multiple sclerosis (MS) model. Our aim is to investigate the impact of demographic and clinical variables o...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2016.1200538
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abstract::This study compared children with ADHD (n = 19), reading disorder (RD; n = 17), ADHD+RD (n = 21), and control children (n = 19) on linguistic and executive function measures. We found no evidence of response inhibition problems in ADHD or RD when a baseline measure of functioning was taken into account. General workin...
journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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abstract::To evaluate the construct and predictive validity of a brief neuropsychological assessment battery, consecutive admissions to a hospital receiving inpatient treatment for stroke were tested with the Repeatable Battery for Assessment of Neuropsychological Status (RBANS) and other neuropsychological measures. Discrimina...
journal_title:Journal of clinical and experimental neuropsychology
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abstract::Past research has found links among cerebrovascular risk factors (CVRFs), depression, and cognition in older adults. This study investigated how well baseline cerebrovascular burden and depression predicted verbal fluency three and six months later. Participants were 139 medical rehabilitation patients, age 60 and abo...
journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章,评审
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abstract::Asymptomatic persons at risk for Huntington's disease (HD) (N = 28) were assessed with neuropsychological, psychiatric, and neurologic tests while undergoing genetic linkage studies to determine their probability of carrying the HD gene. Those participants who were subsequently identified as probable gene carriers did...
journal_title:Journal of clinical and experimental neuropsychology
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abstract::This study explores the presence of homogeneous subgroups among 156 normal elderly subjects based on their performance on a battery of neuropsychological tests. Subjects ranged in age between 57 and 85 years and included 62 males and 94 females with a mean age 70.7 years, mean education 14.1 years, and mean Full Scale...
journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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abstract::The diagnostic validity of new demographically corrected WAIS-III norms was investigated using a sample of 100 patients with traumatic brain injury (TBI) and a matched control group from the standardization sample. Demographically corrected norms were compared to traditional age-corrected norms. Although education acc...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
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更新日期:2005-08-01 00:00:00
abstract:INTRODUCTION:The cognitive processing in patients with functional dyspepsia (FD) has not been well established. Decision-making is an important component of cognitive function. Most brain regions involved in decision-making are abnormal in FD patients. This study aimed to investigate the decision-making under ambiguity...
journal_title:Journal of clinical and experimental neuropsychology
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abstract::Although recognized as one of the most common hereditary diseases of the nervous system, the neuropsychological deficits in Friedreich's ataxia (FA) have rarely been studied. A protocol was constructed to assess the major cognitive areas in patients with FA and pair-matched normal controls. Motor difficulties, dysarth...
journal_title:Journal of clinical and experimental neuropsychology
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更新日期:2002-08-01 00:00:00
abstract:INTRODUCTION:This study was designed to assess sex differences in older adults (55-65 years old) in executive functions and to examine the influence of hormone therapy (HT) in postmenopausal women. METHOD:We have assessed task performance in memory, visuospatial, and executive functions in 29 women using HT, 29 women ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
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abstract::Previous studies have attributed poor memory for words after left temporal lobectomy (LTL) to a verbal memory deficit and poor memory for abstract designs after right temporal lobectomy (RTL) to a difficulty in remembering nonverbal/visual stimuli. In this investigation, the contribution of stimulus novelty to lateral...
journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章,评审
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abstract::Dual-task studies have employed various cognitive tasks to evaluate the relationship between gait and cognition. Most of these tests are not specific to a single cognitive ability or sensory modality and have limited ecological validity. In this study, we employed a dual-task paradigm using Dichotic Listening (DL) as ...
journal_title:Journal of clinical and experimental neuropsychology
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