Abstract：
:The present review integrates findings of published studies that have evaluated the cognitive function of treated and untreated type 2 diabetic patients and provides a detailed overview of the neuropsychological assessments conducted. Cognitive deficits are observed in older people with glucose intolerance or untreated diabetes but these deficits appear to be attenuated by treatments that improve glycemic control. Cognitive decrements in treated type 2 diabetic patients are most consistently observed on measures of verbal memory (35% of the measures) and processing speed (45% of the measures) while preserved function is observed on measures of visuospatial, attention, semantic and language function. Some studies suggest that deficits in cognitive functions are associated with poorer glycemic control. A number of other factors, such as depression, cardiovascular and cerebrovascular disease, increase these deficits. We conclude that, in diabetic patients who achieve and maintain good glycemic control, type 2 diabetes only has a small impact on cognitive functions before the age of 70 years. However, early onset of type 2 diabetes, poor glycemic control and the presence of micro- and macrovascular disease may interact to produce early cognitive deficits. In older adults (70 years and over), diabetes likely interacts with other dementing processes such as vascular disease and Alzheimer's disease to hasten cognitive decline.
journal_name
J Clin Exp Neuropsycholjournal_title
Journal of clinical and experimental neuropsychologyauthors
Awad N,Gagnon M,Messier Cdoi
10.1080/13803390490514875subject
Has Abstractpub_date
2004-11-01 00:00:00pages
1044-80issue
8eissn
1380-3395issn
1744-411Xpii
T65J2EV8RC9WLLD3journal_volume
26pub_type
杂志文章,评审abstract：:This study investigated executive aspects of working memory in a severe closed-head injured (CHI) population. Thirty-four severe CHI participants (>1 year postinjury) and 34 controls completed an abstract design version of Petrides and Milner's (1982) self-ordered pointing task. CHI participants made more errors than ...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1076/jcen.25.7.918.16484
更新日期：2003-10-01 00:00:00
abstract：INTRODUCTION:Language dysfunction has recently been suggested to be one route to alexithymia, an impairment in recognizing and communicating one's own emotions. Neuropsychological evidence is needed to investigate the possibility that acquired language problems could underlie acquired alexithymia. METHOD:This project ...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803395.2020.1770703
更新日期：2020-07-01 00:00:00
abstract：:The literature suggests that nondeclarative, or nonconscious, learning might be impaired among HIV-seropositive (HIV+) individuals compared with HIV-seronegative (HIV-) matched control groups, but these studies have included relatively few women. We administered measures of motor skill and probabilistic learning, task...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803395.2010.493150
更新日期：2011-01-01 00:00:00
abstract：:Introduction: Multiple Sclerosis (MS) is achronic neurological condition that requires costly treatment for aconstellation of motor and sensory symptoms, as well as fatigue, depression, and cognitive problems. Given that this pharmacological treatment often results in side effects, there is acrucial need for low-costb...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803395.2019.1614535
更新日期：2019-09-01 00:00:00
abstract：:Alcohol and substance (drugs and/or alcohol) abuse are major risk factors for traumatic brain injury (TBI); however, it remains unclear whether outcomes differ for those with and without a history of preinjury abuse. A meta-analysis was performed to examine this issue. The PubMed, Embase, and PsycINFO databases were s...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章,meta分析,评审
doi：10.1080/13803395.2016.1248812
更新日期：2017-08-01 00:00:00
abstract：:Parkinson's disease (PD) is a neurodegenerative movement disorder presenting with subcortical pathology and characterized by motor deficits. However, as is frequently reported in the literature, patients with PD can also exhibit cognitive and behavioral (i.e., nonmotor) impairments, cognitive executive deficits and de...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803390500246910
更新日期：2006-10-01 00:00:00
abstract：:The study aimed to provide independent data on the specificity of the Nonverbal Medical Symptom Validity Test (NV-MSVT; Green, 2008 ), a new test that combines conventional decision making based on cutoffs with profile analyses in order to identify invalid test performance and to reduce false positive classifications....
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803390902791653
更新日期：2010-01-01 00:00:00
abstract：:There is an increasing need for standardized assessment of cognition in older patients that is relatively brief, easy to administer, and has normative data adjusted for age and educational attainment. We tested 332 literate, cognitively normal, Spanish persons older than 49 years from the Memory Clinic of Fundació ACE...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803395.2011.630652
更新日期：2012-01-01 00:00:00
abstract：:Memory for pairs of unfamiliar children's faces was investigated in 29 children and adolescents suffering from left (LTLE) or right (RTLE) temporal-lobe epilepsy, before and after temporal-lobe surgery. Both immediate and delayed memory were tested. Before surgery, RTLE subjects performed worse than either LTLE subjec...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/01688639408402670
更新日期：1994-08-01 00:00:00
abstract：:The neuropsychological functioning of adults with Attention Deficit Hyperactivity Disorder (ADHD) was compared to that of healthy controls and individuals with mild psychiatric disorders including attentional complaints. Thirty adults in each group were examined on the Conners' Continuous Performance Test (CPT) and me...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1076/1380-3395(200002)22:1;1-8;FT115
更新日期：2000-02-01 00:00:00
abstract：:Prior to anesthesia with propofol for gastrointestinal endoscopy, sets of pictures were presented to 20 children and adolescents (M age = 12 years). Word pairs (e.g., "hiking-woods") were presented via earphones after the children were anesthetized. Upon regaining consciousness, the children were tested for explicit m...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1076/jcen.21.4.535.888
更新日期：1999-08-01 00:00:00
abstract：:Eight malingerers (MPs) were identified via significantly below-chance symptom validity testing (SVT) within a sample of 106 consecutive admissions for neuropsychological evaluation. The resulting incidence of 7.5% is seen as a minimal estimate of malingering within the sample. Eight individuals who "passed" SVT but p...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/01688639308402580
更新日期：1993-07-01 00:00:00
abstract：INTRODUCTION:There have been suggestions of hypofrontality in cannabis users. To understand cannabis-related differences in decisional processes, Janis and Mann's conflict model of decision making was applied to recreational cannabis smokers who varied in their alcohol use and level of psychological distress. METHOD:A...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803395.2016.1255311
更新日期：2017-09-01 00:00:00
abstract：:A sample of 278 men and 353 elderly women who resided in the community received the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) as part of a study of health in mature adult Oklahomans. Females attained significantly higher scores on the Immediate and Delayed Memory and the Language Index...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1076/jcen.25.8.1065.16732
更新日期：2003-12-01 00:00:00
abstract：:Impulsivity is considered a core feature of problem gambling; however, self-reported impulsivity and inhibitory control may reflect disparate constructs. We examined self-reported impulsivity and inhibitory control in 39 treatment-seeking problem gamblers and 41 matched controls using a range of self-report questionna...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803395.2013.873773
更新日期：2014-01-01 00:00:00
abstract：:Differences in the responses of an elderly biracial group of cognitively normal subjects to a 15-item short version of the Boston Naming Test developed for the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) were examined. The subjects consisted of 103 Whites and 136 African Americans who were 70 ye...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 临床试验,杂志文章
doi：10.1080/01688639708403851
更新日期：1997-04-01 00:00:00
abstract：:Huntington disease (HD) is a neurodegenerative disease associated with cognitive, motor, and psychiatric deterioration over time. Although there is currently no cure for HD, there has been a surge of clinical trials available to patients with HD over the past 5 years. However, cognitive measures have generally been la...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803390903313564
更新日期：2010-07-01 00:00:00
abstract：:The course of decline was studied in 16 patients with probable or definite dementia of the Alzheimer type (DAT) over 2.7 to 6.8 years from first to last evaluation. Overall severity of dementia was measured with the Wechsler Adult Intelligence Scale (WAIS), the Dementia Rating Scale (DRS), and the Mini-Mental State Ex...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/01688639208402846
更新日期：1992-07-01 00:00:00
abstract：:Forty-one patients with putative Alzheimer's Disease (AD) were evaluated to determine the diagnostic utility of a profile of Wechsler Adult Intelligence Scale (WAIS) subtests which has been proposed by Fuld (1984) to identify cholinergic dysfunction. Only nine (21.9%) of these patients had positive Wechsler profiles. ...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/01688638708405359
更新日期：1987-04-01 00:00:00
abstract：:The frequency and characteristics of apraxia in 63 stroke patients with left- or right-hemisphere damage were examined. Analyses focussing on five dimensions of gestural performance revealed an overall frequency of apraxia of 54% in patients with LHD and 30% in patients with RHD. Although both groups were impaired on ...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 临床试验,杂志文章
doi：10.1076/jcen.20.5.628.1128
更新日期：1998-10-01 00:00:00
abstract：:The effects of depressive symptoms on prospective and retrospective memory were examined in a population-based sample of elderly persons (n = 404). Depression was assessed using the Comprehensive Psychopathological Rating Scale and treated as a continuous variable. The variation in depressive symptoms ranged from no s...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803390701380591
更新日期：2008-04-01 00:00:00
abstract：:This study determined whether the Vocabulary-Digit Span difference score and discriminant function based on subtests of the Wechsler Adult Intelligence Scale-Revised (WAIS-R) developed by Mittenberg et al. (1995) could differentiate patients with moderate and severe traumatic brain injuries (n = 50) from persons with ...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1076/jcen.20.2.167.1171
更新日期：1998-04-01 00:00:00
abstract：:A battery of psychoeducational tests was administered to samples of high-functioning (IQ > 70) autistic subjects and normal controls. A previous psychoeducational study indicated the presence of preserved procedural and mechanical academic skills accompanied by impaired comprehension and interpretive skills in high-fu...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/01688639408402680
更新日期：1994-10-01 00:00:00
abstract：OBJECTIVE:Both working memory (WM; a brain system that provides temporary storage and manipulation of the information) and attention-deficit/hyperactivity disorder (ADHD) have been associated with educational deficits. Since WM deficits are prevalent in children with ADHD, the main aim of the present study was to exami...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803395.2015.1127896
更新日期：2016-01-01 00:00:00
abstract：:Semantic memory for generic knowledge was assessed in patients with probable Alzheimer's disease (AD; n = 142) and elderly normal control (NC; n = 78) subjects using the Number Information Test (NIT), a test that consists of 24 general knowledge questions that require a single number for an answer (e.g., "How many day...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 临床试验,杂志文章
doi：10.1080/01688639708403766
更新日期：1997-12-01 00:00:00
abstract：:In spite of demonstrated validity, Halstead's Category Test has been criticized as overly time consuming. In order to evaluate this assumption, groups of severely head-injured and general neurological cases were administered the Category Test as part of routine evaluation, and the time to completion of the test was re...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/01688638608405190
更新日期：1986-12-01 00:00:00
abstract：:In this study, we compared neuropsychological tests and parent-based ratings of flexibility in a sample of children with autism spectrum disorders (ASD). We investigated the discriminant validity of the domain-specific flexibility measures by comparison with the domain general measures, general behavioral problems, ge...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803395.2012.670209
更新日期：2012-01-01 00:00:00
abstract：:Meta-analytic methods were used to determine the sensitivity of neuropsychological, structural, and physiological measures to temporal-hippocampal system function in dementia of the Alzheimer's type. Effect sizes are reported for the California Verbal Learning Test, the Wechsler Memory Scale-Revised, structural (i.e.,...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章,meta分析
doi：10.1076/jcen.20.2.259.1174
更新日期：1998-04-01 00:00:00
abstract：INTRODUCTION:Functional magnetic resonance imaging studies have shown changes in the activity of medial prefrontal, medial temporal, and occipital regions in major depressive disorder patients during recall of autobiographical memories. Electrophysiological underpinning of these changes is not known. It is also not cle...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 杂志文章
doi：10.1080/13803395.2016.1219318
更新日期：2017-04-01 00:00:00
abstract：:Lang (1989) suggested that patients with Wilson's disease do not have memory deficits, unless they suffer from severe neurologic impairment. Results from three recent studies conflict with this view. The interaction of neurologic and cognitive deficits in Wilson's disease is discussed. ...
journal_title：Journal of clinical and experimental neuropsychology
pub_type： 评论,杂志文章
doi：10.1080/01688639108401049
更新日期：1991-03-01 00:00:00
